Andre Bernards

Andre Bernards

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Andre Bernards

Andre Bernards

Publications by authors named "Andre Bernards"

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Passenger Hotspot Mutations in Cancer.

Cancer Cell 2019 Sep;36(3):288-301.e14

The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Center for Cancer Research, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Medical School, 250 Longwood Avenue, Boston, MA 02115, USA; Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.08.002DOI Listing
September 2019

p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity.

J Cell Biol 2018 09 22;217(9):3183-3201. Epub 2018 Jun 22.

GI Cell Biology Research Laboratory, Boston Children's Hospital and Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1083/jcb.201710058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122998PMC
September 2018

Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis.

J Biol Chem 2017 02 22;292(7):2679-2689. Epub 2016 Dec 22.

From the Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129

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http://www.jbc.org/lookup/doi/10.1074/jbc.M116.769216
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http://dx.doi.org/10.1074/jbc.M116.769216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314166PMC
February 2017

A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved in systemic and synaptic growth.

Rare Dis 2014 25;2:e28341. Epub 2014 Feb 25.

Massachusetts General Hospital Center for Cancer Research and Harvard Medical School; Charlestown, MA USA ; Center for Human Genetic Research; Massachusetts General Hospital; Boston, MA USA.

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http://dx.doi.org/10.4161/rdis.28341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091572PMC
July 2014

Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency.

PLoS Genet 2013 Nov 21;9(11):e1003958. Epub 2013 Nov 21.

Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts, United States of America ; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836801PMC
November 2013

The receptor tyrosine kinase Alk controls neurofibromin functions in Drosophila growth and learning.

PLoS Genet 2011 Sep 15;7(9):e1002281. Epub 2011 Sep 15.

Institute of Cellular and Developmental Biology, Biomedical Sciences Research Centre "Alexander Fleming," Vari, Greece.

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https://dx.plos.org/10.1371/journal.pgen.1002281
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http://dx.doi.org/10.1371/journal.pgen.1002281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174217PMC
September 2011

Loss of the Ras regulator RASAL1: another route to Ras activation in colorectal cancer.

Gastroenterology 2009 Jan 28;136(1):46-8. Epub 2008 Nov 28.

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http://dx.doi.org/10.1053/j.gastro.2008.11.024DOI Listing
January 2009

Ras superfamily and interacting proteins database.

Authors:
Andre Bernards

Methods Enzymol 2006 ;407:1-9

Massachusetts General Hospital, Center for Cancer Research, Charlestown, Massachusetts, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S007668790507001
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http://dx.doi.org/10.1016/S0076-6879(05)07001-1DOI Listing
June 2008

GEFs in growth factor signaling.

Growth Factors 2007 Oct;25(5):355-61

Harvard Medical School and Massachusetts General Hospital, Center for Cancer Research, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1080/08977190701830375DOI Listing
October 2007

Drosophila melanogaster neurofibromatosis-1: ROS, not Ras?

Nat Genet 2007 Apr;39(4):443-5

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http://dx.doi.org/10.1038/ng0407-443DOI Listing
April 2007

IQGAP1 regulates adult neural progenitors in vivo and vascular endothelial growth factor-triggered neural progenitor migration in vitro.

J Neurosci 2007 Apr;27(17):4716-24

Institut National de la Santé et de la Recherche Médicale, Unité 873, Laboratoire Transduction du Signal, F-38054 Grenoble, France.

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http://dx.doi.org/10.1523/JNEUROSCI.0830-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672986PMC
April 2007

Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons.

Genes Dev 2006 Dec 17;20(23):3311-23. Epub 2006 Nov 17.

Massachusetts General Hospital Center for Cancer Research and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1101/gad.1466806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1686607PMC
December 2006

GAPs in growth factor signalling.

Growth Factors 2005 Jun;23(2):143-9

Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA.

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http://www.tandfonline.com/doi/full/10.1080/0897719050013048
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http://dx.doi.org/10.1080/08977190500130480DOI Listing
June 2005

GAP control: regulating the regulators of small GTPases.

Trends Cell Biol 2004 Jul;14(7):377-85

MGH Cancer Center and Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1016/j.tcb.2004.05.003DOI Listing
July 2004

IQGAP2 functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization.

Blood 2003 Apr 19;101(8):3021-8. Epub 2002 Dec 19.

Department of Medicine and the Program in Genetics, State University of New York, Stony Brook, 11794, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2002-09-28
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http://dx.doi.org/10.1182/blood-2002-09-2807DOI Listing
April 2003

GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila.

Authors:
André Bernards

Biochim Biophys Acta 2003 Mar;1603(2):47-82

Massachusetts General Hospital Cancer Center, Building 149, 13th Street, Charlestown, MA 02129-2000, USA.

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http://dx.doi.org/10.1016/s0304-419x(02)00082-3DOI Listing
March 2003

Neurofibromin regulates G protein-stimulated adenylyl cyclase activity.

Nat Neurosci 2002 Feb;5(2):95-6

Cold Spring Harbor Laboratory, PO Box 100, Cold Spring Harbor, New York 11724, USA.

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http://www.nature.com/articles/nn792
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http://dx.doi.org/10.1038/nn792DOI Listing
February 2002

Defective proliferative responses in B lymphocytes and thymocytes that lack neurofibromin.

Mol Immunol 2002 Feb;38(9):701-8

Cancer Center, Massachusetts General Hospital, Building 149, 13th Street, Charlestown Navy Yard, Boston, MA 02129, USA.

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http://dx.doi.org/10.1016/s0161-5890(01)00101-8DOI Listing
February 2002