Publications by authors named "Andras Váradi"

100Publications

Pyrophosphate therapy prevents trauma-induced calcification in the mouse model of neurogenic heterotopic ossification.

J Cell Mol Med 2020 Oct 4;24(20):11791-11799. Epub 2020 Sep 4.

Institute of Enzymology, Research Center for Natural Sciences, Hungarian Academy of Sciences Centre of Excellence, Budapest, Hungary.

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http://dx.doi.org/10.1111/jcmm.15793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579705PMC
October 2020

Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain.

Cell Mol Neurobiol 2020 May 18. Epub 2020 May 18.

Center for Clinical Pharmacology, St Louis College of Pharmacy and Washington University School of Medicine, St Louis, MO, USA.

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http://dx.doi.org/10.1007/s10571-020-00867-6DOI Listing
May 2020

The coronavirus-induced COVID-19 pandemic. Previous experiences and scientific evidences at the end of March, 2020

Orv Hetil 2020 04 1;161(17):644-651. Epub 2020 Apr 1.

Általános Orvostudományi Kar, Genetikai, Sejt- és Immunbiológiai Intézet,Semmelweis EgyetemBudapest, Nagyvárad tér 4., 1089.

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http://dx.doi.org/10.1556/650.2020.31830DOI Listing
April 2020

Synthesis of spiro-2,6-dioxopiperazine and spiro-2,6-dioxopyrazine scaffolds using amino acids in a three-component reaction to generate potential Sigma-1 (σ) receptor selective ligands.

Eur J Med Chem 2019 Feb 22;164:241-251. Epub 2018 Dec 22.

Department of Neurology and Molecular Pharmacology, Memorial Sloan Kettering Cancer Center, NY, USA; Center for Clinical Pharmacology, St. Louis College of Pharmacy and Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.12.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361672PMC
February 2019

Dietary Pyrophosphate Modulates Calcification in a Mouse Model of Pseudoxanthoma Elasticum: Implication for Treatment of Patients.

J Invest Dermatol 2019 05 20;139(5):1082-1088. Epub 2018 Nov 20.

Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478508PMC
May 2019

PXE, a Mysterious Inborn Error Clarified.

Trends Biochem Sci 2019 02 13;44(2):125-140. Epub 2018 Nov 13.

Department of Dermatology and Cutaneous Biology and PXE International Center of Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.tibs.2018.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340748PMC
February 2019

In vitro transport of methotrexate by Drosophila Multidrug Resistance-associated Protein.

PLoS One 2018 12;13(10):e0205657. Epub 2018 Oct 12.

Institute of Enzymology, Research Center for Natural Sciences-Hungarian Academy of Sciences, Budapest, Hungary.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205657PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6185855PMC
April 2019

Tissue-nonspecific alkaline phosphatase: a promising target for pseudoxanthoma elasticum therapy.

Ann Transl Med 2017 Dec;5(24):489

Institute of Enzymology, RCNS, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.21037/atm.2017.10.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750270PMC
December 2017

14-O-Methylmorphine: A Novel Selective Mu-Opioid Receptor Agonist with High Efficacy and Affinity.

Eur J Pharmacol 2017 Nov 30;814:264-273. Epub 2017 Aug 30.

Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, P.O. Box 370, H-1445 Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2017.08.034DOI Listing
November 2017

New opioid receptor antagonist: Naltrexone-14-O-sulfate synthesis and pharmacology.

Eur J Pharmacol 2017 Aug 11;809:111-121. Epub 2017 May 11.

Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, Semmelweis University, Nagyvárad tér 4, P.O. Box 370, H-1445 Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2017.05.024DOI Listing
August 2017

Genetic dissociation of morphine analgesia from hyperalgesia in mice.

Psychopharmacology (Berl) 2017 Jun 25;234(12):1891-1900. Epub 2017 Mar 25.

Department of Neurology and Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s00213-017-4600-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520541PMC
June 2017

Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6 Mice.

J Invest Dermatol 2017 03 5;137(3):595-602. Epub 2016 Nov 5.

Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326614PMC
March 2017

New Morphine Analogs Produce Peripheral Antinociception within a Certain Dose Range of Their Systemic Administration.

J Pharmacol Exp Ther 2016 10 19;359(1):171-81. Epub 2016 Jul 19.

Departments of Pharmacology and Pharmacotherapy (E.L., P.R., Z.G., L.C., M.B., K.K., Z.S.Z., P.F., S.F., M.A.) and Pharmaceutical Chemistry (A.V., S.H.), Faculty of Medicine, Semmelweis University, Budapest, Hungary; Department of Anaesthesiology and Intensive Care Medicine, Charité University Berlin, Campus Virchow Klinikum and Campus Charité Mitte, Berlin, Germany (S.A.M., M.S.); Department of Pharmacology and Pharmacotherapy, Medical School, Szentágothai Research Centre (K.C., Z.H.), and MTA-PTE NAP B Chronic Pain Research Group, Faculty of Medicine (Z.H.), University of Pécs, Pécs, Hungary

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http://dx.doi.org/10.1124/jpet.116.233551DOI Listing
October 2016

New perspectives on rare connective tissue calcifying diseases.

Curr Opin Pharmacol 2016 06 27;28:14-23. Epub 2016 Feb 27.

The Roslin Institute, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Easter Bush, Midlothian, EH25 9RG Scotland, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2016.02.002DOI Listing
June 2016

Research Progress in Pseudoxanthoma Elasticum and Related Ectopic Mineralization Disorders.

J Invest Dermatol 2016 Mar;136(3):550-556

Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2015.10.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765001PMC
March 2016

Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles.

Molecules 2015 Dec 23;21(1):E19. Epub 2015 Dec 23.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

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http://www.mdpi.com/1420-3049/21/1/19
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http://dx.doi.org/10.3390/molecules21010019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782750PMC
December 2015

Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behavior.

ACS Chem Neurosci 2015 Nov 14;6(11):1813-24. Epub 2015 Sep 14.

Molecular Pharmacology and Chemistry Program, Department of Neurology, Memorial Sloan Kettering Cancer Center , 1275 York Avenue, New York, New York 10065, United States.

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http://dx.doi.org/10.1021/acschemneuro.5b00153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651729PMC
November 2015

Mild, Pd-catalyzed stannylation of radioiodination targets.

Bioorg Med Chem Lett 2015 Apr 2;25(8):1761-1764. Epub 2015 Mar 2.

Molecular Pharmacology and Chemistry Program, Department of Neurology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X150017
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http://dx.doi.org/10.1016/j.bmcl.2015.02.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385467PMC
April 2015

It is all about calcification.

Authors:
András Váradi

Cell Cycle 2014 ;13(24):3793

a Institute of Enyzmology, RCNS ; Hungarian Academy of Sciences.

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http://www.tandfonline.com/doi/full/10.4161/15384101.2014.98
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http://dx.doi.org/10.4161/15384101.2014.980706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614523PMC
May 2015

Hungary: Research agency will lose autonomy.

Nature 2014 Dec;516(7531):329

Central European University, Hungary.

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http://dx.doi.org/10.1038/516329cDOI Listing
December 2014

Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter.

Biochim Biophys Acta 2015 Feb 14;1848(2):477-87. Epub 2014 Nov 14.

Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar tudósok körútja 2., H-1117 Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2014.11.006DOI Listing
February 2015

ABCC6-mediated ATP secretion by the liver is the main source of the mineralization inhibitor inorganic pyrophosphate in the systemic circulation-brief report.

Arterioscler Thromb Vasc Biol 2014 Sep 26;34(9):1985-9. Epub 2014 Jun 26.

From the Division of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands (R.S.J., S.M., D.S., P.B., K.v.d.W.); Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands (S.D., R.P.J.O.E.); Institute of Enzymology, RCNS, Hungarian Academy of Sciences, Budapest, Hungary (F.S., A.V.); Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands (A.P., A.A.B.); and Netherlands Institute for Neuroscience, Amsterdam, The Netherlands (A.A.B.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743317PMC
September 2014

Three-component coupling approach for the synthesis of diverse heterocycles utilizing reactive nitrilium trapping.

Org Lett 2014 Mar 28;16(6):1668-71. Epub 2014 Feb 28.

Department of Neurology, Memorial Sloan Kettering Cancer Center , 1275 York Avenue, New York, New York 10065, United States.

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http://dx.doi.org/10.1021/ol500328tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969103PMC
March 2014

Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites.

Drug Metab Dispos 2014 Apr 2;42(4):575-85. Epub 2014 Jan 2.

Institute of Molecular Pharmacology, Research Centre for Natural Sciences, Hungarian Academy of Sciences (A.T., B.S.); Molecular Biophysics Research Group, Hungarian Academy of Sciences and Semmelweis University (C.H.); and Institute of Enzymology, Research Centre for Natural Sciences, Hungarian Academy of Sciences (A.V., C.O.-L.), Budapest, Hungary.

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http://dx.doi.org/10.1124/dmd.113.055731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965895PMC
April 2014

Analysis of pseudoxanthoma elasticum-causing missense mutants of ABCC6 in vivo; pharmacological correction of the mislocalized proteins.

J Invest Dermatol 2014 Apr 11;134(4):946-953. Epub 2013 Nov 11.

Institute of Enzymology, RCNS, Hungarian Academy of Sciences, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1038/jid.2013.482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962510PMC
April 2014

Novel 6β-acylaminomorphinans with analgesic activity.

Eur J Med Chem 2013 Nov 22;69:786-9. Epub 2013 Sep 22.

Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes E. u. 9, Budapest H-1092, Hungary; Molecular Pharmacology and Chemistry Program and Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2013.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839676PMC
November 2013

Synthetic and quantum chemical study on the regioselective addition of amines to methyl maleamate.

J Mol Model 2013 Sep 19;19(9):3683-94. Epub 2013 Jun 19.

Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes E. u. 9., 1092, Budapest, Hungary.

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http://dx.doi.org/10.1007/s00894-013-1905-xDOI Listing
September 2013

Pseudoxanthoma elasticum: progress in research toward treatment: summary of the 2012 PXE international research meeting.

J Invest Dermatol 2013 Jun;133(6):1444-9

Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1038/jid.2013.20DOI Listing
June 2013

The molecular and physiological roles of ABCC6: more than meets the eye.

Front Genet 2012 12;3:289. Epub 2012 Dec 12.

Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii Honolulu, HI, USA.

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http://dx.doi.org/10.3389/fgene.2012.00289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520154PMC
December 2012

Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein.

Biochem J 2013 Mar;450(2):387-95

Biomembrane Laboratory, Institute of Molecular Pharmacology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Diószegi ut 64, 1113 Budapest, Hungary.

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http://www.biochemj.org/content/ppbiochemj/450/2/387.full.pd
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http://biochemj.org/lookup/doi/10.1042/BJ20121485
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http://dx.doi.org/10.1042/BJ20121485DOI Listing
March 2013

Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters.

Biochem Biophys Res Commun 2012 Sep 16;426(2):172-6. Epub 2012 Aug 16.

Institute of Enzymology, Research Center for Natural Sciences, Hungarian Academy of Sciences, Karolina ut 29, 1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.bbrc.2012.08.046DOI Listing
September 2012

ABCC6 expression is regulated by CCAAT/enhancer-binding protein activating a primate-specific sequence located in the first intron of the gene.

J Invest Dermatol 2012 Dec 5;132(12):2709-17. Epub 2012 Jul 5.

Laboratory of Transcriptional Regulation, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.

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http://dx.doi.org/10.1038/jid.2012.218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509247PMC
December 2012

Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance.

Biochem Pharmacol 2012 Aug 21;84(3):260-7. Epub 2012 Apr 21.

Membrane Research Group of the Hungarian Academy of Sciences, Department of Biophysics, Semmelweis University and National Blood Center, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.bcp.2012.04.010DOI Listing
August 2012

PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter.

Biochem Biophys Res Commun 2012 Apr 24;420(4):869-74. Epub 2012 Mar 24.

Membrane Research Group of the Hungarian Academy of Sciences, Department of Biophysics, Semmelweis University and National Blood Center, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.bbrc.2012.03.090DOI Listing
April 2012

Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter.

Eur J Pharm Sci 2012 Jan 17;45(1-2):101-9. Epub 2011 Nov 17.

Membrane Research Group of Hungarian Academy of Sciences, Department of Biophysics, Semmelweis University and National Blood Center, Diószegi u 64, H-1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.ejps.2011.10.021DOI Listing
January 2012

Expression and in vivo rescue of human ABCC6 disease-causing mutants in mouse liver.

PLoS One 2011 14;6(9):e24738. Epub 2011 Sep 14.

Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024738PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173462PMC
February 2012

ABCC6 does not transport adenosine - relevance to pathomechanism of pseudoxanthoma elasticum.

Mol Genet Metab 2011 Nov 20;104(3):421; author reply 422. Epub 2011 Jul 20.

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http://dx.doi.org/10.1016/j.ymgme.2011.07.013DOI Listing
November 2011

ABCC6 as a target in pseudoxanthoma elasticum.

Curr Drug Targets 2011 May;12(5):671-82

Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324121PMC
http://dx.doi.org/10.2174/138945011795378612DOI Listing
May 2011

Sulfate esters of morphine derivatives: synthesis and characterization.

Eur J Pharm Sci 2011 Jan 27;42(1-2):65-72. Epub 2010 Oct 27.

Department of Pharmaceutical Chemistry, Semmelweis University, Hőgyes Endre u. 9, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.ejps.2010.10.007DOI Listing
January 2011

The abcc6a gene expression is required for normal zebrafish development.

J Invest Dermatol 2010 Nov 1;130(11):2561-8. Epub 2010 Jul 1.

Department of Dermatology and Cutaneous Biology, Jefferson Medical College and Jefferson Institute of Molecular Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1038/jid.2010.174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357064PMC
November 2010

Model system for the analysis of cell surface expression of human ABCA1.

BMC Cell Biol 2009 Dec 21;10:93. Epub 2009 Dec 21.

Membrane Biology Research Group, Hungarian Academy of Sciences, Department of Biophysics and Radiation Biology, Semmelweis University, Diószegi u 64, H-1113, Budapest, Hungary.

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http://dx.doi.org/10.1186/1471-2121-10-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804593PMC
December 2009

Clustering of disease-causing mutations on the domain-domain interfaces of ABCC6.

Biochem Biophys Res Commun 2009 Feb 6;379(3):706-9. Epub 2009 Jan 6.

Institute of Enzymology, Hungarian Academy of Sciences, Karolina ut 29, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.bbrc.2008.12.142DOI Listing
February 2009

The high turnover Drosophila multidrug resistance-associated protein shares the biochemical features of its human orthologues.

Biochim Biophys Acta 2009 Feb 20;1788(2):402-9. Epub 2008 Nov 20.

Institute of Enzymology, Hungarian Academy of Sciences, Budapest, P.O. Box 7, H-1518, Hungary.

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http://linkinghub.elsevier.com/retrieve/pii/S000527360800370
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http://dx.doi.org/10.1016/j.bbamem.2008.11.007DOI Listing
February 2009

Pseudoxanthoma elasticum: clinical phenotypes, molecular genetics and putative pathomechanisms.

Exp Dermatol 2009 Jan 22;18(1):1-11. Epub 2008 Oct 22.

Departments of Dermatology and Cutaneous Biology, and Biochemistry and Molecular Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1111/j.1600-0625.2008.00795.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349969PMC
January 2009

How segmental duplications shape our genome: recent evolution of ABCC6 and PKD1 Mendelian disease genes.

Mol Biol Evol 2008 Dec 12;25(12):2601-13. Epub 2008 Sep 12.

Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1093/molbev/msn202DOI Listing
December 2008

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

Drug Discov Today 2008 May 20;13(9-10):379-93. Epub 2008 Feb 20.

National Medical Center, Institute of Haematology and Immunology, Membrane Research Group of the Hungarian Academy of Sciences, H-1113 Budapest, Diószegi u. 64, Hungary.

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http://dx.doi.org/10.1016/j.drudis.2007.12.010DOI Listing
May 2008

Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter.

Biochim Biophys Acta 2007 Nov 10;1768(11):2698-713. Epub 2007 Jul 10.

National Medical Center, Institute of Hematology and Immunology, Membrane Research Group of Hung. Acad Sci, 1113, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.bbamem.2007.06.026DOI Listing
November 2007

Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity.

FEBS Lett 2006 Nov 16;580(26):6139-44. Epub 2006 Oct 16.

National Medical Center, Institute of Haematology and Immunology, Membrane Research Group of the Hungarian Academy of Sciences, H-1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.febslet.2006.10.012DOI Listing
November 2006

The BiSearch web server.

BMC Bioinformatics 2006 Oct 5;7:431. Epub 2006 Oct 5.

lnstitute of Enzymology, BRC, HAS, H-1113 Karolina út 29, Budapest, Hungary.

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http://dx.doi.org/10.1186/1471-2105-7-431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1609187PMC
October 2006

Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system.

Physiol Rev 2006 Oct;86(4):1179-236

National Medical Center, Institute of Hematology and Immunology, Membrane Research Group, Budapest, Hungary.

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http://physrev.physiology.org/content/physrev/86/4/1179.full
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http://physrev.physiology.org/cgi/doi/10.1152/physrev.00037.
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http://dx.doi.org/10.1152/physrev.00037.2005DOI Listing
October 2006

Genotype-phenotype correlations in Hungarian patients with hereditary medullary thyroid cancer.

Wien Klin Wochenschr 2006 Jul;118(13-14):417-21

2nd Department of Medicine, Faculty of Medicine, Semmelweis University, Szentkiralyi u. 46, 1088 Budapest, Hungary.

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http://dx.doi.org/10.1007/s00508-006-0635-9DOI Listing
July 2006

The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology.

Cancer Lett 2006 Mar 7;234(1):62-72. Epub 2005 Dec 7.

National Medical Center, Institute of Hematology and Immunology, Diószegi u. 64, 1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.canlet.2005.01.061DOI Listing
March 2006

Membrane topology of human ABC proteins.

FEBS Lett 2006 Feb 1;580(4):1017-22. Epub 2005 Dec 1.

Institute of Enzymology, Hungarian Academy of Sciences, Karolina út 29, 1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.febslet.2005.11.040DOI Listing
February 2006

Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6.

J Biol Chem 2005 May 9;280(19):18643-50. Epub 2005 Mar 9.

Institute of Enzymology, Hungarian Academy of Sciences, H-1113 Budapest, Hungary.

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http://dx.doi.org/10.1074/jbc.M501139200DOI Listing
May 2005

Functional expression of a multidrug P-glycoprotein transporter of Leishmania.

Biochem Biophys Res Commun 2005 Apr;329(2):502-7

Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, Parque Tecnológico de Ciencias de la Salud, Avda. del Conocimiento s/n, 18100 Armilla, Granada, Spain.

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http://dx.doi.org/10.1016/j.bbrc.2005.02.009DOI Listing
April 2005

Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition.

Biochim Biophys Acta 2005 Feb;1668(1):53-63

National Medical Center, Institute of Haematology and Immunology, Membrane Research Group of the Hungarian Academy of Sciences, Diószegi út 64., H-1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.bbamem.2004.11.005DOI Listing
February 2005

BiSearch: primer-design and search tool for PCR on bisulfite-treated genomes.

Nucleic Acids Res 2005 Jan 13;33(1):e9. Epub 2005 Jan 13.

Institute of Enzymology, BRC, Hungarian Academy of Sciences H-1113 Budapest, Karolina út 29, Hungary.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gni012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC546182PMC
January 2005

Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface.

J Biol Chem 2005 Feb 22;280(6):4219-27. Epub 2004 Nov 22.

National Medical Center, Institute of Haematology and Immunology, Membrane Research Group and Hungarian Academy of Sciences, 1113 Budapest, Hungary.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M411338200
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http://dx.doi.org/10.1074/jbc.M411338200DOI Listing
February 2005

The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers.

J Biol Chem 2004 Oct 12;279(40):41670-8. Epub 2004 Jul 12.

Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1074/jbc.M406484200DOI Listing
October 2004

ABCG2 -- a transporter for all seasons.

FEBS Lett 2004 Jun;567(1):116-20

National Medical Center, Institute of Haematology and Immunology, Membrane Research Group of the Hungarian Academy of Sciences, Diószegi u. 64, H-1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.febslet.2004.03.123DOI Listing
June 2004

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.

Mol Pharmacol 2004 Jun;65(6):1485-95

National Medical Center, Institute of Hematology and Immunology, Membrane Research Group of the Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1124/mol.65.6.1485DOI Listing
June 2004

Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells.

Biochem Biophys Res Commun 2003 Aug;308(2):263-9

Institute of Enzymology, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1016/s0006-291x(03)01349-4DOI Listing
August 2003

Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate.

Biofactors 2003 ;17(1-4):103-14

Membrane Research Group, Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1002/biof.5520170111DOI Listing
February 2004

Analysis of large structural changes of the factor VIII gene, involving intron 1 and 22, in severe hemophilia A.

Haematologica 2003 Jul;88(7):778-84

Institute of Hematology and Immunology, National Medical Center, Diószegi út 64, Budapest H-1113, Hungary.

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July 2003

Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions.

J Biol Chem 2003 Jun 19;278(26):23529-37. Epub 2003 Apr 19.

National Medical Center, Institute of Haematology and Immunology, Membrane Research Group of the Hungarian Academy of Sciences.

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http://dx.doi.org/10.1074/jbc.M303515200DOI Listing
June 2003

The role of multidrug transporters in drug availability, metabolism and toxicity.

Toxicol Lett 2003 Apr;140-141:133-43

National Medical Center, Institute of Haematology and Immunology, Membrane Research Group of the Hungarian Academy of Sciences, Budapest, Hungary.

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http://dx.doi.org/10.1016/s0378-4274(02)00497-6DOI Listing
April 2003

Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells.

Hum Gene Ther 2003 Mar;14(4):403-12

Institute of Hematology and Immunology, National Medical Center, Hungarian Academy of Sciences, Diószegi u. 64, H-1113 Budapest, Hungary.

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http://dx.doi.org/10.1089/104303403321209005DOI Listing
March 2003

C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins.

Biochem Biophys Res Commun 2003 Mar;302(3):454-61

Department of Molecular Cell Biology, Membrane Research Group of the Hungarian Academy of Sciences, National Medical Center, Diószegi u. 64, 1113 Budapest, Hungary.

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http://dx.doi.org/10.1016/s0006-291x(03)00196-7DOI Listing
March 2003