Anders Albrechtsen

Anders Albrechtsen

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Anders Albrechtsen

Anders Albrechtsen

Publications by authors named "Anders Albrechtsen"

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Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing.

Nucleic Acids Res 2019 Aug 31. Epub 2019 Aug 31.

Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, DK-2200 Copenhagen N, Denmark.

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http://dx.doi.org/10.1093/nar/gkz736DOI Listing
August 2019

Ancestry-specific association mapping in admixed populations.

Genet Epidemiol 2019 07 18;43(5):506-521. Epub 2019 Mar 18.

Department of Biology, The Bioinformatics Centre, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/gepi.22200DOI Listing
July 2019

Testing for Hardy-Weinberg equilibrium in structured populations using genotype or low-depth next generation sequencing data.

Mol Ecol Resour 2019 Apr 11. Epub 2019 Apr 11.

Section for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1111/1755-0998.13019DOI Listing
April 2019

DamMet: ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage.

Gigascience 2019 04;8(4)

Lundbeck Foundation GeoGenetics Center, University of Copenhagen, Øster Voldgade 5-7, 1350K Copenhagen, Denmark.

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http://dx.doi.org/10.1093/gigascience/giz025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474913PMC
April 2019

Allele frequency-free inference of close familial relationships from genotypes or low-depth sequencing data.

Mol Ecol 2019 01;28(1):35-48

Section for Computational and RNA Biology, Department of Biology, University of Copenhagen, Copenhagen N, Denmark.

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http://dx.doi.org/10.1111/mec.14954DOI Listing
January 2019

Inferring Population Structure and Admixture Proportions in Low-Depth NGS Data.

Genetics 2018 10 21;210(2):719-731. Epub 2018 Aug 21.

The Bioinformatics Centre, Department of Biology, University of Copenhagen, DK-2200, Denmark.

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http://dx.doi.org/10.1534/genetics.118.301336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6216594PMC
October 2018

Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population.

Diabetologia 2018 09 20;61(9):2005-2015. Epub 2018 Jun 20.

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00125-018-4659-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096637PMC
September 2018

Diabetes in Population Isolates: Lessons from Greenland.

Rev Diabet Stud 2015 Fall-Winter;12(3-4):320-9. Epub 2016 Feb 10.

Section for Metabolic Genetics, The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1900/RDS.2015.12.320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5275757PMC
July 2018

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population.

Eur J Hum Genet 2018 06 26;26(6):868-875. Epub 2018 Feb 26.

The Novo Nordisk Foundation Center for Basic Metabolic Research, Section for Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41431-018-0109-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974304PMC
June 2018

Genetic architecture of obesity and related metabolic traits-recent insights from isolated populations.

Curr Opin Genet Dev 2018 06 3;50:74-78. Epub 2018 Mar 3.

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2018.02.010DOI Listing
June 2018

A southern African origin and cryptic structure in the highly mobile plains zebra.

Nat Ecol Evol 2018 03 22;2(3):491-498. Epub 2018 Jan 22.

Department of Biology, Section for Computational and RNA Biology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41559-017-0453-7DOI Listing
March 2018

Powerful Inference with the D-Statistic on Low-Coverage Whole-Genome Data.

G3 (Bethesda) 2018 02 2;8(2):551-566. Epub 2018 Feb 2.

Center for Bioinformatics, Faculty of Science, University of Copenhagen, 2100, Denmark.

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http://dx.doi.org/10.1534/g3.117.300192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919751PMC
February 2018

fastNGSadmix: admixture proportions and principal component analysis of a single NGS sample.

Bioinformatics 2017 Oct;33(19):3148-3150

Department of Biology, The Bioinformatics Centre, University of Copenhagen, 2200 Copenhagen N, Denmark.

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http://dx.doi.org/10.1093/bioinformatics/btx474DOI Listing
October 2017

Archaic Adaptive Introgression in TBX15/WARS2.

Mol Biol Evol 2017 03;34(3):509-524

Department of Integrative Biology, University of California Berkeley, Berkeley, CA.

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http://dx.doi.org/10.1093/molbev/msw283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430617PMC
March 2017

Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation.

J Hum Genet 2017 Feb 13;62(2):151-157. Epub 2016 Oct 13.

Centre for Genomic Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/jhg.2016.118DOI Listing
February 2017

Next-generation biology: Sequencing and data analysis approaches for non-model organisms.

Mar Genomics 2016 Dec 13;30:3-13. Epub 2016 May 13.

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.margen.2016.04.012DOI Listing
December 2016

A genomic history of Aboriginal Australia.

Nature 2016 Oct 21;538(7624):207-214. Epub 2016 Sep 21.

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nature18299DOI Listing
October 2016

Estimating IBD tracts from low coverage NGS data.

Bioinformatics 2016 07 22;32(14):2096-102. Epub 2016 Apr 22.

Department of Biology, University of Copenhagen, Copenhagen, Denmark and Department of Integrative Biology, University of California, Berkeley, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw212DOI Listing
July 2016

Genetics of Type 2 Diabetes: the Power of Isolated Populations.

Curr Diab Rep 2016 07;16(7):65

The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 1, 2100, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s11892-016-0757-zDOI Listing
July 2016

Partial USH2A deletions contribute to Usher syndrome in Denmark.

Eur J Hum Genet 2015 Dec 25;23(12):1646-51. Epub 2015 Mar 25.

Clinical Genetics Clinic, The Kennedy Center, Rigshospitalet, University of Copenhagen, Glostrup, Denmark.

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http://dx.doi.org/10.1038/ejhg.2015.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795208PMC
December 2015

Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis.

Mult Scler 2015 Oct 22;21(11):1414-22. Epub 2014 Dec 22.

Department of Neurology, Rigshospitalet, Copenhagen University Hospital, Danish Multiple Sclerosis Center, Denmark.

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http://journals.sagepub.com/doi/10.1177/1352458514563590
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http://dx.doi.org/10.1177/1352458514563590DOI Listing
October 2015

Greenlandic Inuit show genetic signatures of diet and climate adaptation.

Science 2015 Sep;349(6254):1343-7

Department of Integrative Biology, University of California-Berkeley, Berkeley, CA 94720, USA. Department of Statistics, University of California-Berkeley, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1126/science.aab2319DOI Listing
September 2015

POPULATION GENETICS. Genomic evidence for the Pleistocene and recent population history of Native Americans.

Authors:
Maanasa Raghavan Matthias Steinrücken Kelley Harris Stephan Schiffels Simon Rasmussen Michael DeGiorgio Anders Albrechtsen Cristina Valdiosera María C Ávila-Arcos Anna-Sapfo Malaspinas Anders Eriksson Ida Moltke Mait Metspalu Julian R Homburger Jeff Wall Omar E Cornejo J Víctor Moreno-Mayar Thorfinn S Korneliussen Tracey Pierre Morten Rasmussen Paula F Campos Peter de Barros Damgaard Morten E Allentoft John Lindo Ene Metspalu Ricardo Rodríguez-Varela Josefina Mansilla Celeste Henrickson Andaine Seguin-Orlando Helena Malmström Thomas Stafford Suyash S Shringarpure Andrés Moreno-Estrada Monika Karmin Kristiina Tambets Anders Bergström Yali Xue Vera Warmuth Andrew D Friend Joy Singarayer Paul Valdes Francois Balloux Ilán Leboreiro Jose Luis Vera Hector Rangel-Villalobos Davide Pettener Donata Luiselli Loren G Davis Evelyne Heyer Christoph P E Zollikofer Marcia S Ponce de León Colin I Smith Vaughan Grimes Kelly-Anne Pike Michael Deal Benjamin T Fuller Bernardo Arriaza Vivien Standen Maria F Luz Francois Ricaut Niede Guidon Ludmila Osipova Mikhail I Voevoda Olga L Posukh Oleg Balanovsky Maria Lavryashina Yuri Bogunov Elza Khusnutdinova Marina Gubina Elena Balanovska Sardana Fedorova Sergey Litvinov Boris Malyarchuk Miroslava Derenko M J Mosher David Archer Jerome Cybulski Barbara Petzelt Joycelynn Mitchell Rosita Worl Paul J Norman Peter Parham Brian M Kemp Toomas Kivisild Chris Tyler-Smith Manjinder S Sandhu Michael Crawford Richard Villems David Glenn Smith Michael R Waters Ted Goebel John R Johnson Ripan S Malhi Mattias Jakobsson David J Meltzer Andrea Manica Richard Durbin Carlos D Bustamante Yun S Song Rasmus Nielsen Eske Willerslev

Science 2015 Aug 21;349(6250):aab3884. Epub 2015 Jul 21.

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.

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http://dx.doi.org/10.1126/science.aab3884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733658PMC
August 2015

Uncovering the genetic history of the present-day Greenlandic population.

Am J Hum Genet 2015 Jan 31;96(1):54-69. Epub 2014 Dec 31.

The Bioinformatics Centre, Department of Biology, University of Copenhagen, 2200 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289681PMC
January 2015

ANGSD: Analysis of Next Generation Sequencing Data.

BMC Bioinformatics 2014 Nov 25;15:356. Epub 2014 Nov 25.

Centre for GeoGenetics, Natural History Museum of Denmark, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/s12859-014-0356-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248462PMC
November 2014

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population.

Eur J Hum Genet 2014 Aug 22;22(8):1040-5. Epub 2014 Jan 22.

1] Bioinformatics Research Centre, Aarhus University, C.F. Mollers Alle, 8000 Aarhus C, Denmark [2] Department of Bioscience, Aarhus University, Ny Munkegade, 8000 Aarhus C., Denmark.

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http://dx.doi.org/10.1038/ejhg.2013.282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350597PMC
August 2014

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes.

Nature 2014 Aug 18;512(7513):190-3. Epub 2014 Jun 18.

1] The Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark [2] Faculty of Health Sciences, University of Southern Denmark, 5000 Odense, Denmark.

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http://dx.doi.org/10.1038/nature13425DOI Listing
August 2014

RelateAdmix: a software tool for estimating relatedness between admixed individuals.

Bioinformatics 2014 Apr 8;30(7):1027-8. Epub 2013 Nov 8.

Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA and Department of Biology, The Bioinformatics Centre, University of Copenhagen, 2200 Copenhagen N, Denmark.

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http://dx.doi.org/10.1093/bioinformatics/btt652DOI Listing
April 2014

Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation.

Genome Res 2013 Nov 15;23(11):1852-61. Epub 2013 Aug 15.

Department of Integrative Biology, University of California, Berkeley, Berkeley, California 94720, USA;

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http://dx.doi.org/10.1101/gr.157388.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814885PMC
November 2013

Quantifying population genetic differentiation from next-generation sequencing data.

Genetics 2013 Nov 26;195(3):979-92. Epub 2013 Aug 26.

Department of Integrative Biology, University of California, Berkeley, California 94720.

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http://dx.doi.org/10.1534/genetics.113.154740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813878PMC
November 2013

Estimating individual admixture proportions from next generation sequencing data.

Genetics 2013 Nov 11;195(3):693-702. Epub 2013 Sep 11.

The Bioinformatics Centre, Department of Biology, University of Copenhagen, DK-2200 Copenhagen N.

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http://dx.doi.org/10.1534/genetics.113.154138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813857PMC
November 2013

Calculation of Tajima's D and other neutrality test statistics from low depth next-generation sequencing data.

BMC Bioinformatics 2013 Oct 2;14:289. Epub 2013 Oct 2.

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Oestervoldgade 5-7, DK-1350, Copenhagen, Denmark.

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http://dx.doi.org/10.1186/1471-2105-14-289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015034PMC
October 2013

Association testing for next-generation sequencing data using score statistics.

Genet Epidemiol 2012 Jul 8;36(5):430-7. Epub 2012 May 8.

Department of Biology, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/gepi.21636DOI Listing
July 2012

A method for detecting IBD regions simultaneously in multiple individuals--with applications to disease genetics.

Genome Res 2011 Jul 14;21(7):1168-80. Epub 2011 Apr 14.

The Bioinformatics Centre, Department of Biology, University of Copenhagen, Copenhagen, Denmark.

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http://genome.cshlp.org/cgi/doi/10.1101/gr.115360.110
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http://dx.doi.org/10.1101/gr.115360.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129259PMC
July 2011

Genotype and SNP calling from next-generation sequencing data.

Nat Rev Genet 2011 Jun;12(6):443-51

Department of Integrative Biology, University of California, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.1038/nrg2986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593722PMC
June 2011

Ascertainment biases in SNP chips affect measures of population divergence.

Mol Biol Evol 2010 Nov 17;27(11):2534-47. Epub 2010 Jun 17.

Department of Biostatistics, Copenhagen University, Copenhagen, Denmark.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
Publisher Site
http://dx.doi.org/10.1093/molbev/msq148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107607PMC
November 2010

Natural selection and the distribution of identity-by-descent in the human genome.

Genetics 2010 Sep 30;186(1):295-308. Epub 2010 Jun 30.

Department of Biostatistics, University of Copenhagen, Copenhagen, 1014, Denmark.

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http://dx.doi.org/10.1534/genetics.110.113977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940294PMC
September 2010

The validation and assessment of machine learning: a game of prediction from high-dimensional data.

PLoS One 2009 Aug 4;4(8):e6287. Epub 2009 Aug 4.

Tune H Pers Center for Biological Sequence Analysis, Department of Systems Biology, The Technical University of Denmark, Kongens Lyngby, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0006287PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716515PMC
August 2009

Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families.

Breast Cancer Res Treat 2009 May 12;115(2):315-23. Epub 2008 Jun 12.

Department of Clinical Biochemistry 4111, Rigshospitalet, Blegdamsvej 9, Copenhagen 2100, Denmark.

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http://dx.doi.org/10.1007/s10549-008-0088-0DOI Listing
May 2009

Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium.

Genet Epidemiol 2009 Apr;33(3):266-74

Department of Biostatistics, Copenhagen University, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/gepi.20378DOI Listing
April 2009

A Bayesian multilocus association method: allowing for higher-order interaction in association studies.

Genetics 2007 Jun 15;176(2):1197-208. Epub 2007 Apr 15.

Bioinformatics Centre, University of Copenhagen, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1534/genetics.107.071696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894584PMC
June 2007

Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.

J Clin Endocrinol Metab 2007 Jan 31;92(1):363-6. Epub 2006 Oct 31.

Steno Diabetes Center, Niels Steensens Vej 2, 2820 Gentofte, Denmark.

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http://dx.doi.org/10.1210/jc.2006-1958DOI Listing
January 2007