Anahita Dastur

Anahita Dastur

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Anahita Dastur

Anahita Dastur

Publications by authors named "Anahita Dastur"

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12Publications

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Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.

Nature 2014 Jul 22;511(7511):616-20. Epub 2014 Jun 22.

1] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA [2] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature13393DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4244910PMC
July 2014

mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.

Cancer Discov 2014 Jan 25;4(1):42-52. Epub 2013 Oct 25.

1Massachusetts General Hospital Cancer Center; 2Department of Medicine, Harvard Medical School; 3Division of Gastroenterology, Department of Medicine, Tufts Medical Center; 4Department of Pathology, Massachusetts General Hospital, Boston; and 5Radiation Oncology, Steele Lab for Tumor Biology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973435PMC
January 2014

Transposon activation mutagenesis as a screening tool for identifying resistance to cancer therapeutics.

BMC Cancer 2013 Feb 27;13:93. Epub 2013 Feb 27.

Center for Molecular Therapeutics, Center for Cancer Research, Massachusetts General Hospital, and Harvard Medical School, CNY 149-Rm7308, Thirteenth St. Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1186/1471-2407-13-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598783PMC
February 2013

Herc5, an interferon-induced HECT E3 enzyme, is required for conjugation of ISG15 in human cells.

J Biol Chem 2006 Feb 28;281(7):4334-8. Epub 2005 Dec 28.

Institute for Cellular and Molecular Biology, Section of Molecular Genetics and Microbiology, The University of Texas at Austin, 78712, USA.

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http://dx.doi.org/10.1074/jbc.M512830200DOI Listing
February 2006

Expression and assay of HECT domain ligases.

Methods Enzymol 2005 ;398:112-25

Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, TX 78712-1095, USA.

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http://dx.doi.org/10.1016/S0076-6879(05)98011-7DOI Listing
December 2005

The -4 phenylalanine is required for substrate ubiquitination catalyzed by HECT ubiquitin ligases.

J Biol Chem 2004 Apr 13;279(18):18935-43. Epub 2004 Feb 13.

Institute for Cellular and Molecular Biology, Section of Molecular Genetics and Microbiology, University of Texas at Austin, Austin, Texas 78712, USA.

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http://dx.doi.org/10.1074/jbc.M312201200DOI Listing
April 2004

Analysis of the initiator tRNA genes from a slow- and a fast-growing Mycobacterium.

Arch Microbiol 2002 Oct 24;178(4):288-96. Epub 2002 Jul 24.

Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, 560 012, India.

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http://dx.doi.org/10.1007/s00203-002-0460-0DOI Listing
October 2002