Ana Vivancos

Ana Vivancos

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Ana Vivancos

Ana Vivancos

Publications by authors named "Ana Vivancos"

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53Publications

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Multicenter Phase II Study of Lurbinectedin in BRCA-Mutated and Unselected Metastatic Advanced Breast Cancer and Biomarker Assessment Substudy.

J Clin Oncol 2018 11 21;36(31):3134-3143. Epub 2018 Sep 21.

Cristina Cruz and Judith Balmaña, Vall d'Hebron Hospital; Cristina Cruz, Alba Llop-Guevara, Joaquín Arribas, Ana Vivancos, Violeta Serra, and Judith Balmaña, Vall d'Hebron Institute of Oncology; José A. Pérez Fidalgo, Ana Lluch, Joaquín Arribas, and Violeta Serra, Centro de Investigación Biomédica en Red; Joaquín Arribas, Institució Catalana de Recerca i Estudis Avançats, Barcelona; José A. Pérez Fidalgo and Ana Lluch, Hospital Clínico de Valencia, Valencia; Cristian Fernández, Carmen Kahatt, Carlos M. Galmarini, Arturo Soto-Matos, Vicente Alfaro, and Aitor Pérez de la Haza, PharmaMar, Madrid; Silvia Antolin, Complejo Universitario Hospitalario La Coruña, La Coruña; Rafael Lopez, Complejo Hospitalario Universitario Santiago de Compostela, Santiago de Compostela, Spain; Judy E. Garber, Dana Farber Cancer Institute; Nadine M. Tung, Beth Israel Deaconess Medical Center; José Baselga and Steven J. Isakoff, Massachusetts General Hospital Cancer Center, Boston, MA; Banu K. Arun, MD Anderson Cancer Center, Houston, TX; Melinda L. Telli, Stanford University School of Medicine, Stanford, CA; Susan M. Domchek, University of Pennsylvania, Philadelphia, PA; and Linda Vahdat, Weill Cornell Medicine, New York, NY.

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http://dx.doi.org/10.1200/JCO.2018.78.6558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209089PMC
November 2018

Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations.

Genome Med 2018 03 28;10(1):25. Epub 2018 Mar 28.

Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Medical, Research Institute and Pompeu Fabra University, Barcelona, Spain.

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http://dx.doi.org/10.1186/s13073-018-0531-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5875005PMC
March 2018

Genetic profile of GNAQ-mutated blue melanocytic neoplasms reveals mutations in genes linked to genomic instability and the PI3K pathway.

Oncotarget 2016 May;7(19):28086-95

Biomedical Research in Melanoma-Animal Models and Cancer Laboratory, Oncology Program, Vall d'Hebron Research institute, VHIR-Vall d'Hebron Hospital, Barcelona-UAB 08035, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053711PMC
http://dx.doi.org/10.18632/oncotarget.8578DOI Listing
May 2016

Genetic evolution of nevus of Ota reveals clonal heterogeneity acquiring BAP1 and TP53 mutations.

Pigment Cell Melanoma Res 2016 Mar;29(2):247-53

Biomedical Research in Melanoma-Animal Models and Cancer Laboratory, Vall dHebron Research Institute-VHIR Vall d'Hebron Hospital, Autonomous University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/pcmr.12452DOI Listing
March 2016

Spatiotemporal Control of Forkhead Binding to DNA Regulates the Meiotic Gene Expression Program.

Cell Rep 2016 Feb 21;14(4):885-895. Epub 2016 Jan 21.

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona 08003, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.074DOI Listing
February 2016

Defining a minimal cell: essentiality of small ORFs and ncRNAs in a genome-reduced bacterium.

Mol Syst Biol 2015 Jan 21;11(1):780. Epub 2015 Jan 21.

EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), Barcelona, Spain Universitat Pompeu Fabra (UPF), Barcelona, Spain Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332154PMC
http://dx.doi.org/10.15252/msb.20145558DOI Listing
January 2015

New approach to cancer therapy based on a molecularly defined cancer classification.

CA Cancer J Clin 2014 Jan-Feb;64(1):70-4. Epub 2013 Nov 18.

Head of the Breast Cancer and Melanoma Programs, Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Barcelona, Spain; Medical Oncologist, Medica Scientia Innovation Research (MedSIR), Barcelona, Spain.

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http://dx.doi.org/10.3322/caac.21211DOI Listing
March 2014

A personalized preclinical model to evaluate the metastatic potential of patient-derived colon cancer initiating cells.

Clin Cancer Res 2013 Dec 29;19(24):6787-801. Epub 2013 Oct 29.

Authors' Affiliations: Translational Program, Stem Cells and Cancer Laboratory; Molecular Oncology Group; Genomics Cancer Group; and Translational Genomics Group, Vall d'Hebron Institute of Oncology (VHIO); Parc de Recerca Biomèdica de Barcelona (PRBB), Centre d'Imatge Molecular (CRC) Corporació Sanitària; Departments of Pathology, Medical Oncology, and HBP Surgery and Transplantation, Vall d'Hebron University Hospital, Universidad Autónoma de Barcelona; and General Surgery Service, Vall d'Hebron University Hospital, Barcelona, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-1740DOI Listing
December 2013

Genomic analyses across six cancer types identify basal-like breast cancer as a unique molecular entity.

Sci Rep 2013 Dec 18;3:3544. Epub 2013 Dec 18.

1] Breast Cancer Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain [2] Medical Oncology Department, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.

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http://dx.doi.org/10.1038/srep03544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506566PMC
December 2013

Clinical response to a lapatinib-based therapy for a Li-Fraumeni syndrome patient with a novel HER2V659E mutation.

Cancer Discov 2013 Nov 15;3(11):1238-44. Epub 2013 Aug 15.

1Vall d'Hebron Institut d'Oncologia; 2Vall d'Hebron Institut de Recerca; 3Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona; 4Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo, Spain; and 5Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0132DOI Listing
November 2013

Circulating tumour cells and cell-free DNA as tools for managing breast cancer.

Nat Rev Clin Oncol 2013 Jul 28;10(7):377-89. Epub 2013 May 28.

Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Paseo Vall d'Hebron 119-129, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1038/nrclinonc.2013.80DOI Listing
July 2013

Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.

Mol Cancer Ther 2012 Sep 21;11(9):2062-71. Epub 2012 Jun 21.

Molecular Therapeutics Research Unit, Medical Oncology Department, Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://mct.aacrjournals.org/content/11/9/2062.full.pdf
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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-12
Publisher Site
http://dx.doi.org/10.1158/1535-7163.MCT-12-0290DOI Listing
September 2012

Transcription start site associated RNAs in bacteria.

Mol Syst Biol 2012 May 22;8:585. Epub 2012 May 22.

Center for Genomic Regulation (CRG), UPF, Barcelona, Spain.

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http://dx.doi.org/10.1038/msb.2012.16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377991PMC
May 2012

Molecular prescreening to select patient population in early clinical trials.

Nat Rev Clin Oncol 2012 04 3;9(6):359-66. Epub 2012 Apr 3.

Medical Oncology Department, Vall d'Hebrón University Hospital, Spain.

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http://dx.doi.org/10.1038/nrclinonc.2012.48DOI Listing
April 2012

Strand-specific deep sequencing of the transcriptome.

Genome Res 2010 Jul 2;20(7):989-99. Epub 2010 Jun 2.

Centre for Genomic Regulation (CRG), UPF, 08003 Barcelona, Spain.

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http://genome.cshlp.org/cgi/doi/10.1101/gr.094318.109
Publisher Site
http://dx.doi.org/10.1101/gr.094318.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892100PMC
July 2010

C-terminal truncation of the peroxiredoxin Tpx1 decreases its sensitivity for hydrogen peroxide without compromising its role in signal transduction.

Genes Cells 2008 Feb;13(2):171-9

Oxidative Stress and Cell Cycle Group, Universitat Pompeu Fabra, C/Dr. Aiguader 88, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1365-2443.2007.01160.xDOI Listing
February 2008

The peroxiredoxin Tpx1 is essential as a H2O2 scavenger during aerobic growth in fission yeast.

Mol Biol Cell 2007 Jun 4;18(6):2288-95. Epub 2007 Apr 4.

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1091/mbc.e06-11-1039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1877099PMC
June 2007

Oxidative stress in Schizosaccharomyces pombe: different H2O2 levels, different response pathways.

Mol Genet Genomics 2006 Dec 17;276(6):495-502. Epub 2006 Oct 17.

Cell Signalling Unit, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Dr. Aiguader 80, Barcelona, 08003, Spain.

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http://dx.doi.org/10.1007/s00438-006-0175-zDOI Listing
December 2006

The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe.

J Biol Chem 2005 Nov 1;280(44):36708-13. Epub 2005 Sep 1.

Cell Signaling Unit, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Dr. Aiguader 80, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1074/jbc.M508400200DOI Listing
November 2005

A cysteine-sulfinic acid in peroxiredoxin regulates H2O2-sensing by the antioxidant Pap1 pathway.

Proc Natl Acad Sci U S A 2005 Jun 13;102(25):8875-80. Epub 2005 Jun 13.

Cell Signaling Unit, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Dr. Aiguader 80, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1073/pnas.0503251102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1157045PMC
June 2005

Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration.

Mol Microbiol 2004 Jun;52(5):1427-35

Cell Signalling Unit, Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Dr Aiguader 80, E-08003 Barcelona, Spain.

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http://dx.doi.org/10.1111/j.1365-2958.2004.04065.xDOI Listing
June 2004

Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1.

J Biol Chem 2003 Oct 1;278(42):40565-72. Epub 2003 Aug 1.

Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, C/Dr Aiguader 80, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1074/jbc.M305859200DOI Listing
October 2003