Ana Pombo

Ana Pombo

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Ana Pombo

Publications by authors named "Ana Pombo"

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Inference of chromosome 3D structures from GAM data by a physics computational approach.

Methods 2019 Oct 8. Epub 2019 Oct 8.

Dipartimento di Fisica, Università di Napoli Federico II, and INFN Napoli, Complesso Universitario di Monte Sant'Angelo, 80126 Naples, Italy; Berlin Institute of Health (BIH), MDC-Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2019.09.018DOI Listing
October 2019

Fungal diversity and mycotoxin distribution in echinoderm aquaculture.

Mycotoxin Res 2019 Aug 22;35(3):253-260. Epub 2019 Mar 22.

H&TRC- Health & Technology Research Center, ESTeSL- Escola Superior de Tecnologia da Saúde, Instituto Politécnico de Lisboa, Lisbon, Portugal.

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http://link.springer.com/10.1007/s12550-019-00352-0
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http://dx.doi.org/10.1007/s12550-019-00352-0DOI Listing
August 2019

Editorial overview: Genome architecture and expression.

Curr Opin Genet Dev 2019 Apr;55:iii-iv

Berlin Institute for Medical Systems Biology, Germany.

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http://dx.doi.org/10.1016/j.gde.2019.09.001DOI Listing
April 2019

R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes.

Mol Cell 2019 03 29;73(5):930-945.e4. Epub 2019 Jan 29.

Berlin Institute for Medical Systems Biology, Max Delbrueck Centre for Molecular Medicine, Berlin-Buch 13092, Germany; Berlin Institute of Health, Berlin, Germany; Institute for Biology, Humboldt-Universitat zu Berlin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414425PMC
March 2019

Polymer physics predicts the effects of structural variants on chromatin architecture.

Nat Genet 2018 05 16;50(5):662-667. Epub 2018 Apr 16.

Dipartimento di Fisica, Università di Napoli Federico II, and INFN Napoli, Complesso di Monte Sant'Angelo, Naples, Italy.

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http://dx.doi.org/10.1038/s41588-018-0098-8DOI Listing
May 2018

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Cell cycle: Continuous chromatin changes.

Nature 2017 07;547(7661):34-35

Max Delbrück Center for Molecular Medicine, Berlin Institute for Medical Systems Biology, Berlin 13125, Germany.

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http://dx.doi.org/10.1038/547034aDOI Listing
July 2017

Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells.

Nat Struct Mol Biol 2017 Jun 24;24(6):515-524. Epub 2017 Apr 24.

Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max Delbrück Centre for Molecular Medicine, Berlin, Germany.

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http://dx.doi.org/10.1038/nsmb.3402DOI Listing
June 2017

Flipping between Polycomb repressed and active transcriptional states introduces noise in gene expression.

Nat Commun 2017 06 26;8(1):36. Epub 2017 Jun 26.

European Molecular Biology Laboratory-European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK.

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http://dx.doi.org/10.1038/s41467-017-00052-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484669PMC
June 2017

Keep Them Close: PRC2 Poises Enhancer-Promoter Interactions at Anterior Neuronal Genes.

Cell Stem Cell 2017 05;20(5):573-575

Epigenetic Regulation and Chromatin Architecture, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin-Buch, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.04.006DOI Listing
May 2017

Complex multi-enhancer contacts captured by genome architecture mapping.

Nature 2017 03 8;543(7646):519-524. Epub 2017 Mar 8.

Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine, Robert-Rössle Straße, Berlin-Buch 13125, Germany.

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http://dx.doi.org/10.1038/nature21411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366070PMC
March 2017

A Finer Print Than TADs: PRC1-Mediated Domains.

Mol Cell 2017 Feb;65(3):373-375

Epigenetic Regulation and Chromatin Architecture, Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin-Buch, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.01.028DOI Listing
February 2017

Examining Topological Domain Influence on Enhancer Function.

Dev Cell 2016 12;39(5):523-524

Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine, Robert-Rössle Strasse, Berlin-Buch 13092, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2016.11.011DOI Listing
December 2016

Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription.

Bioessays 2016 09 25;38(9):881-93. Epub 2016 Jul 25.

Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine, Berlin-Buch, Germany.

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http://dx.doi.org/10.1002/bies.201600032DOI Listing
September 2016

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment.

Nat Cell Biol 2016 08 11;18(8):864-75. Epub 2016 Jul 11.

Paul Gerson Unna Group 'Skin Homeostasis and Ageing', Max Planck Institute for Biology of Ageing, 50931 Cologne, Germany.

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http://dx.doi.org/10.1038/ncb3387DOI Listing
August 2016

Nuclear architecture in stem cells.

Adv Exp Med Biol 2010 ;695:14-25

Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.

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http://dx.doi.org/10.1007/978-1-4419-7037-4_2DOI Listing
April 2016

Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells.

Elife 2015 Dec 19;4. Epub 2015 Dec 19.

Epigenetic Regulation and Chromatin Architecture Group, Berlin Institute for Medical Systems Biology, Max-Delbrück Centre for Molecular Medicine, Berlin, Germany.

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http://elifesciences.org/content/elife/early/2015/12/19/eLif
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http://elifesciences.org/lookup/doi/10.7554/eLife.11215
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http://dx.doi.org/10.7554/eLife.11215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758952PMC
December 2015

Physical mechanisms behind the large scale features of chromatin organization.

Transcription 2014 ;5(2):e28447

a Berlin Institute for Medical Systems Biology; Max Delbrück Center for Molecular Medicine; Berlin-Buch, Germany.

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http://dx.doi.org/10.4161/trns.28447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214237PMC
October 2015

Three-dimensional genome architecture: players and mechanisms.

Nat Rev Mol Cell Biol 2015 Apr 11;16(4):245-57. Epub 2015 Mar 11.

Gene Regulation and Chromatin Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1038/nrm3965DOI Listing
April 2015

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Authors:
Erik Arner Carsten O Daub Kristoffer Vitting-Seerup Robin Andersson Berit Lilje Finn Drabløs Andreas Lennartsson Michelle Rönnerblad Olga Hrydziuszko Morana Vitezic Tom C Freeman Ahmad M N Alhendi Peter Arner Richard Axton J Kenneth Baillie Anthony Beckhouse Beatrice Bodega James Briggs Frank Brombacher Margaret Davis Michael Detmar Anna Ehrlund Mitsuhiro Endoh Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley Forrester Daniel Goldowitz Reto Guler Thomas Ha Mitsuko Hara Meenhard Herlyn Tomokatsu Ikawa Chieko Kai Hiroshi Kawamoto Levon M Khachigian S Peter Klinken Soichi Kojima Haruhiko Koseki Sarah Klein Niklas Mejhert Ken Miyaguchi Yosuke Mizuno Mitsuru Morimoto Kelly J Morris Christine Mummery Yutaka Nakachi Soichi Ogishima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Xian-Yang Qin Sugata Roy Hiroki Sato Suzana Savvi Alka Saxena Anita Schwegmann Daisuke Sugiyama Rolf Swoboda Hiroshi Tanaka Andru Tomoiu Louise N Winteringham Ernst Wolvetang Chiyo Yanagi-Mizuochi Misako Yoneda Susan Zabierowski Peter Zhang Imad Abugessaisa Nicolas Bertin Alexander D Diehl Shiro Fukuda Masaaki Furuno Jayson Harshbarger Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Yuri Ishizu Masayoshi Itoh Tsugumi Kawashima Miki Kojima Naoto Kondo Marina Lizio Terrence F Meehan Christopher J Mungall Mitsuyoshi Murata Hiromi Nishiyori-Sueki Serkan Sahin Sayaka Nagao-Sato Jessica Severin Michiel J L de Hoon Jun Kawai Takeya Kasukawa Timo Lassmann Harukazu Suzuki Hideya Kawaji Kim M Summers Christine Wells David A Hume Alistair R R Forrest Albin Sandelin Piero Carninci Yoshihide Hayashizaki

Science 2015 Feb 12;347(6225):1010-4. Epub 2015 Feb 12.

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http://dx.doi.org/10.1126/science.1259418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681433PMC
February 2015

A polymer model explains the complexity of large-scale chromatin folding.

Nucleus 2013 Jul-Aug;4(4):267-73. Epub 2013 Jun 19.

Universita' di Napoli "Federico II"; Dipartimento di Fisica; INFN Sezione di Napoli; CNR-SPIN, Complesso Universitario di Monte S. Angelo; Napoli, Italy; Department of Biochemistry and Goodman Cancer Research Center; McGill University; Montréal, Québec Canada; Berlin Institute for Medical Systems Biology; Max Delbrück Center for Molecular Medicine; Berlin-Buch, Germany; Genome Function Group; MRC Clinical Sciences Centre; Imperial College London; Hammersmith Hospital Campus; London, UK.

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http://dx.doi.org/10.4161/nucl.25432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810333PMC
October 2014

Models of chromosome structure.

Curr Opin Cell Biol 2014 Jun 4;28:90-5. Epub 2014 May 4.

Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, Robert Rössle Strasse 10, 13125 Berlin-Buch, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ceb.2014.04.004DOI Listing
June 2014

An H3K9/S10 methyl-phospho switch modulates Polycomb and Pol II binding at repressed genes during differentiation.

Mol Biol Cell 2014 Mar 15;25(6):904-15. Epub 2014 Jan 15.

Gene Regulation and Chromatin Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London W12 0NN, United Kingdom Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London W12 0NN, United Kingdom MRC Protein Phosphorylation Unit, Sir James Black Centre, University of Dundee, Dundee DD1 5EH, United Kingdom.

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http://dx.doi.org/10.1091/mbc.E13-10-0628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952858PMC
March 2014

Polymer models of chromatin organization.

Front Genet 2013 20;4:113. Epub 2013 Jun 20.

Dipartimento di Fisica, INFN Sezione di Napoli, CNR-SPIN, Universita' di Napoli Federico II Napoli, Italy.

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http://dx.doi.org/10.3389/fgene.2013.00113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687138PMC
June 2013

A model of the large-scale organization of chromatin.

Biochem Soc Trans 2013 Apr;41(2):508-12

Università di Napoli 'Federico II', Dipartimento di Scienze Fisiche, INFN Sezione di Napoli, CNR-SPIN, Complesso Universitario di Monte S. Angelo, Via Cintia, 80126 Napoli, Italy.

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http://dx.doi.org/10.1042/BST20120238DOI Listing
April 2013

Complexity of chromatin folding is captured by the strings and binders switch model.

Proc Natl Acad Sci U S A 2012 Oct 17;109(40):16173-8. Epub 2012 Sep 17.

Dipartimento di Scienze Fisiche, Università di Napoli Federico II, 80126 Naples, Italy.

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http://dx.doi.org/10.1073/pnas.1204799109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479593PMC
October 2012

Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.

Mol Cell Proteomics 2012 Jun 22;11(6):M111.011767. Epub 2011 Dec 22.

MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1074/mcp.M111.011767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433901PMC
June 2012

Code breaking: the RNAPII modification code in pluripotency.

Cell Cycle 2012 Apr 1;11(7):1267-8. Epub 2012 Apr 1.

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http://dx.doi.org/10.4161/cc.19990DOI Listing
April 2012

Nuclear cell biology.

Mol Biol Cell 2011 Mar;22(6):722

Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London W12 0NN, UK.

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http://www.molbiolcell.org/doi/10.1091/mbc.e10-12-0966
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http://dx.doi.org/10.1091/mbc.E10-12-0966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057694PMC
March 2011

Polycomb targets seek closest neighbours.

PLoS Genet 2011 Mar 24;7(3):e1002031. Epub 2011 Mar 24.

Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063758PMC
March 2011

CryoFISH: fluorescence in situ hybridization on ultrathin cryosections.

Methods Mol Biol 2010 ;659:219-30

MRC Clinical Sciences Centre, Imperial College School of Medicine, London, UK.

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http://dx.doi.org/10.1007/978-1-60761-789-1_15DOI Listing
December 2010

Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment.

Development 2010 Aug 23;137(15):2483-92. Epub 2010 Jun 23.

Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, Hammersmith Campus, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1242/dev.048363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927698PMC
August 2010

Gene positioning.

Cold Spring Harb Perspect Biol 2010 Jun 19;2(6):a000588. Epub 2010 May 19.

Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, United Kingdom.

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http://dx.doi.org/10.1101/cshperspect.a000588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869523PMC
June 2010

Nucleus and gene expression: the structure and function conundrum.

Curr Opin Cell Biol 2010 Jun 22;22(3):269-70. Epub 2010 May 22.

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http://dx.doi.org/10.1016/j.ceb.2010.04.010DOI Listing
June 2010

Poised transcription factories prime silent uPA gene prior to activation.

PLoS Biol 2010 Jan 5;8(1):e1000270. Epub 2010 Jan 5.

Laboratory of Molecular Dynamics of the Nucleus, Division of Genetics and Cell Biology, S Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1371/journal.pbio.1000270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797137PMC
January 2010

Modifications of RNA polymerase II are pivotal in regulating gene expression states.

EMBO Rep 2009 Nov 16;10(11):1213-9. Epub 2009 Oct 16.

Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1038/embor.2009.221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775184PMC
November 2009

The molecular basis for stability of heterochromatin-mediated silencing in mammals.

Epigenetics Chromatin 2009 Nov 4;2(1):14. Epub 2009 Nov 4.

Gene Control Mechanisms and Disease Group, MRC Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London W12 0NN, UK.

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http://dx.doi.org/10.1186/1756-8935-2-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2779788PMC
November 2009

3D chromatin regulation of Sonic hedgehog in the limb buds.

Dev Cell 2009 Jan;16(1):9-11

Genome Function Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London, UK.

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http://dx.doi.org/10.1016/j.devcel.2008.12.010DOI Listing
January 2009

Mechanisms regulating S phase progression in mammalian cells.

Front Biosci (Landmark Ed) 2009 Jan 1;14:4199-213. Epub 2009 Jan 1.

Faculty of Life Sciences, University of Manchester, MIB, 131 Princess Street, Manchester, M1 7DN, UK.

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http://dx.doi.org/10.2741/3523DOI Listing
January 2009

Eukaryotic gene regulation in three dimensions and its impact on genome evolution.

Curr Opin Genet Dev 2008 Dec 27;18(6):571-82. Epub 2008 Nov 27.

MRC Laboratory of Molecular Biology, Cambridge, UK.

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http://dx.doi.org/10.1016/j.gde.2008.10.002DOI Listing
December 2008

Changes in chromosome organization during PHA-activation of resting human lymphocytes measured by cryo-FISH.

Chromosome Res 2008 ;16(3):413-26

MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.

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http://link.springer.com/10.1007/s10577-008-1230-x
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http://dx.doi.org/10.1007/s10577-008-1230-xDOI Listing
August 2008

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells.

Nat Cell Biol 2007 Dec 25;9(12):1428-35. Epub 2007 Nov 25.

Nuclear Organisation, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1038/ncb1663DOI Listing
December 2007

Functional organisation of the genome during interphase.

Curr Opin Genet Dev 2007 Oct 24;17(5):451-5. Epub 2007 Oct 24.

Nuclear Organisation Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1016/j.gde.2007.08.008DOI Listing
October 2007

Advances in imaging the interphase nucleus using thin cryosections.

Authors:
Ana Pombo

Histochem Cell Biol 2007 Aug 17;128(2):97-104. Epub 2007 Jul 17.

Nuclear Organisation Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.

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http://link.springer.com/10.1007/s00418-007-0310-x
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http://dx.doi.org/10.1007/s00418-007-0310-xDOI Listing
August 2007

Desmin immunolocalisation in autosomal dominant Emery-Dreifuss muscular dystrophy.

Neuromuscul Disord 2007 Apr 27;17(4):297-305. Epub 2007 Feb 27.

Dubowitz Neuromuscular Unit, Department of Paediatrics, Hammersmith Hospital, Imperial College, London, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S096089660700007
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http://dx.doi.org/10.1016/j.nmd.2007.01.003DOI Listing
April 2007

Chromosome organization: new facts, new models.

Trends Cell Biol 2007 Mar 2;17(3):127-34. Epub 2007 Jan 2.

MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.

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http://dx.doi.org/10.1016/j.tcb.2006.12.006DOI Listing
March 2007

Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations.

PLoS Biol 2006 May 25;4(5):e138. Epub 2006 Apr 25.

MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.0040138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440941PMC
May 2006

Splicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain.

Mol Biol Cell 2006 Apr 8;17(4):1723-33. Epub 2006 Feb 8.

Medical Research Council Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1091/mbc.e05-08-0726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415300PMC
April 2006

Distribution of different phosphorylated forms of RNA polymerase II in relation to Cajal and PML bodies in human cells: an ultrastructural study.

Histochem Cell Biol 2006 Jan 27;125(1-2):21-31. Epub 2005 Sep 27.

MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.

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http://dx.doi.org/10.1007/s00418-005-0064-2DOI Listing
January 2006

Variant histone H3.3 marks promoters of transcriptionally active genes during mammalian cell division.

EMBO Rep 2005 Apr;6(4):354-60

Gene Regulation and Chromatin Group, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College, London W12 0NN, UK.

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http://dx.doi.org/10.1038/sj.embor.7400366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1299280PMC
April 2005

Measuring the size of biological nanostructures with spatially modulated illumination microscopy.

Mol Biol Cell 2004 May 12;15(5):2449-55. Epub 2004 Mar 12.

MRC, Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, United Kingdom.

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http://www.molbiolcell.org/doi/10.1091/mbc.e04-01-0045
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http://dx.doi.org/10.1091/mbc.e04-01-0045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC404036PMC
May 2004

Fixation-induced redistribution of hyperphosphorylated RNA polymerase II in the nucleus of human cells.

Exp Cell Res 2004 May;295(2):460-8

MRC-Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, London W12 0NN, UK.

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http://dx.doi.org/10.1016/j.yexcr.2004.01.020DOI Listing
May 2004

CD8 alpha is an activation marker for a subset of peripheral CD4 T cells.

Eur J Immunol 2004 May;34(5):1262-71

Sir William Dunn School of Pathology, University of Oxford, Oxford, GB.

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http://dx.doi.org/10.1002/eji.200324363DOI Listing
May 2004

Transcription factories: quantitative studies of nanostructures in the mammalian nucleus.

Chromosome Res 2003 ;11(5):461-70

MRC-Clinical Sciences Centre, Faculty of Medicine, Imperial College School of Science, Technology and Medicine, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK.

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April 2004

Interaction of proteins with promoter elements of the human U2 snRNA genes in vivo.

Gene 2003 Oct;315:103-12

Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

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http://dx.doi.org/10.1016/s0378-1119(03)00717-0DOI Listing
October 2003

From linear genome sequence to three-dimensional organization of the cell nucleus.

Genome Biol 2003 28;4(3):310. Epub 2003 Feb 28.

University of Massachusetts Medical School, Department of Biochemistry and Molecular Pharmacology, 377 Plantation Street, Worcester, MA 01605, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153456PMC
http://dx.doi.org/10.1186/gb-2003-4-3-310DOI Listing
March 2003

Cellular genomics: which genes are transcribed, when and where?

Authors:
Ana Pombo

Trends Biochem Sci 2003 Jan;28(1):6-9

MRC - Clinical Sciences Centre, Faculty of Medicine, Imperial College of Science, Technology and Medicine, Hammersmith Hospital Campus, Du Cane Road, W12 0NN, London, UK.

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http://dx.doi.org/10.1016/s0968-0004(02)00011-7DOI Listing
January 2003

Genomics meets nanoscience: probing genes and the cell nucleus at 10-9 meters.

Genome Biol 2002 25;3(3):REPORTS4007. Epub 2002 Feb 25.

MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139022PMC
http://dx.doi.org/10.1186/gb-2002-3-3-reports4007DOI Listing
July 2002