Publications by authors named "Ana Novokmet"

18Publications

Assessment of TP53 Polymorphisms and MDM2 SNP309 in Premenopausal Breast Cancer Risk.

Hum Mutat 2017 03 23;38(3):265-268. Epub 2017 Jan 23.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/humu.23154DOI Listing
March 2017

Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility.

J Clin Oncol 2016 Oct;34(30):3697-3704

Nardin Samuel, Gavin Wilson, James Tran, Meredith Irwin, Rosanna Weksberg, Thomas J. Hudson, and David Malkin, University of Toronto; Nardin Samuel, Badr Id Said, Youliang Lou, Weili Li, Ana Novokmet, James Tran, Sanaa Choufani, Marc Remke, Vijay Ramaswamy, Florence M.G. Cavalli, Michael D. Taylor, Uri Tabori, Meredith Irwin, Rosanna Weksberg, Jonathan D. Wasserman, Andrew D. Paterson, and David Malkin, The Hospital for Sick Children; Nardin Samuel, Gavin Wilson, Mathieu Lemire, and Thomas J. Hudson, Ontario Institute for Cancer Research; Christine Elser, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Diana Merino, National Institutes of Health, Bethesda, MD; Kim E. Nichols, St Jude Children's Research Hospital, Memphis, TN; Jonathan L. Finlay, Nationwide Children's Hospital, Columbus, OH; Lynn Meister, Joe DiMaggio Children's Hospital, Hollywood, FL; Jordan R. Hansford, Children's Cancer Centre, Royal Children's Hospital, Melbourne, Victoria, Australia; and Maria Isabel W. Achatz, Hospital AC Camargo, São Paulo, Brazil.

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http://dx.doi.org/10.1200/JCO.2016.67.6940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366343PMC
October 2016

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study.

Lancet Oncol 2016 Sep 5;17(9):1295-305. Epub 2016 Aug 5.

Department of Pediatrics, University of Toronto, Toronto, ON, Canada; Division of Hematology/Oncology, University of Toronto, Toronto, ON, Canada; Genetics & Genomic Biology Program, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30249-2DOI Listing
September 2016

Super-Transactivation TP53 Variant in the Germline of a Family with Li-Fraumeni Syndrome.

Hum Mutat 2016 09 27;37(9):889-92. Epub 2016 Jun 27.

Department of Pediatrics, Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada.

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http://dx.doi.org/10.1002/humu.23025DOI Listing
September 2016

Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study.

J Clin Oncol 2015 Feb 12;33(6):602-9. Epub 2015 Jan 12.

Jonathan D. Wasserman, Ana Novokmet, Claudia Eichler-Jonsson, and David Malkin, The Hospital for Sick Children; Jonathan D. Wasserman and David Malkin, University of Toronto; Jonathan D. Wasserman and David Malkin, SickKids Research Institute, Toronto, Ontario, Canada; Raul C. Ribeiro and Gerard P. Zambetti, St Jude Children's Research Hospital, Memphis, TN; and Carlos Rodriguez-Galindo, Dana-Farber/Children's Hospital Cancer Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2013.52.6863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517369PMC
February 2015

Parent decision-making around the genetic testing of children for germline TP53 mutations.

Cancer 2015 Jan 15;121(2):286-93. Epub 2014 Sep 15.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.29027DOI Listing
January 2015

Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers.

Cancer 2014 Apr 30;120(7):1068-75. Epub 2013 Dec 30.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Pediatric Hematology/ Oncology, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; Howard Hughes Medical Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, Massachusetts; Joslin Diabetes Center, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncr.28507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173134PMC
April 2014

Routine TP53 testing for breast cancer under age 30: ready for prime time?

Fam Cancer 2012 Dec;11(4):607-13

Division of Gynecologic Oncology, Princess Margaret Hospital, University Health Network, 610 University Avenue, Toronto, Ontario, Canada.

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http://link.springer.com/content/pdf/10.1007/s10689-012-9557
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http://link.springer.com/10.1007/s10689-012-9557-z
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http://dx.doi.org/10.1007/s10689-012-9557-zDOI Listing
December 2012

Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study.

Lancet Oncol 2011 Jun 19;12(6):559-67. Epub 2011 May 19.

Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/S1470-2045(11)70119-XDOI Listing
June 2011

Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma.

Cancer Res 2010 Jan;70(1):160-71

Institute of Medical Science, Department of Medical Biophysics, University of Toronto, and Program in Genetics and Genome Biology, Department of Pediatric Laboratory Medicine, Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1902DOI Listing
January 2010

Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome.

Proc Natl Acad Sci U S A 2008 Aug 6;105(32):11264-9. Epub 2008 Aug 6.

Program in Genetics and Genome Biology, Departments of Medical Biophysics, Centre for Applied Genomics, and Division of Hematology/Oncology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1073/pnas.0802970105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516272PMC
August 2008