Publications by authors named "Ana Losada"

64Publications

Skeletal Anomalies in Senegalese Sole ( Kaup) Fed with Different Commercial Enriched A Study in Postlarvae and Juveniles.

Authors:
Ana Manuela de Azevedo Ana Paula Losada Isabel Ferreiro Ana Riaza Vanesa Losada Tommaso Russo Clara Boglione Sonia Vázquez María Isabel Quiroga

Animals (Basel) 2020 Dec 24;11(1). Epub 2020 Dec 24.

Department of Anatomy, Animal Production and Clinical Veterinary Sciences, Faculty of Veterinary Science, University of Santiago de Compostela, Campus Universitario S/N, 27002 Lugo, Spain.

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December 2020

The Teleost Thymus in Health and Disease: New Insights from Transcriptomic and Histopathological Analyses of Turbot, .

Authors:
Paolo Ronza Diego Robledo Ana Paula Losada Roberto Bermúdez Belén G Pardo Paulino Martínez María Isabel Quiroga

Biology (Basel) 2020 Aug 13;9(8). Epub 2020 Aug 13.

Departamento de Anatomía, Producción Animal y Ciencias Clínicas Veterinarias, Universidade de Santiago de Compostela, 27002 Lugo, Spain.

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August 2020

Essential Roles of Cohesin STAG2 in Mouse Embryonic Development and Adult Tissue Homeostasis.

Authors:
Magali De Koninck Eleonora Lapi Claudio Badía-Careaga Itziar Cossío Daniel Giménez-Llorente Miriam Rodríguez-Corsino Elena Andrada Andrés Hidalgo Miguel Manzanares Francisco X Real Ana Losada

Cell Rep 2020 08;32(6):108014

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain. Electronic address:

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August 2020

Regulatory CDH4 Genetic Variants Associate With Risk to Develop Capecitabine-Induced Hand-Foot Syndrome.

Authors:
Sara Ruiz-Pinto Guillermo Pita Miguel Martín Rocío Nuñez-Torres Ana Cuadrado Marta N Shahbazi Daniela Caronia Alexander Kojic Leticia T Moreno Julio C de la Torre-Montero María Lozano Luis A López-Fernández Nuria Ribelles Jose A García-Saenz Emilio Alba Roger L Milne Ana Losada Mirna Pérez-Moreno Javier Benítez Anna González-Neira

Clin Pharmacol Ther 2020 Aug 5. Epub 2020 Aug 5.

Human Genotyping Unit-Centro Nacional de Genotipado (CEGEN), Human Cancer Genetics Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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August 2020

Specialized functions of cohesins STAG1 and STAG2 in 3D genome architecture.

Authors:
Ana Cuadrado Ana Losada

Curr Opin Genet Dev 2020 04 12;61:9-16. Epub 2020 Apr 12.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain. Electronic address:

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April 2020

PDS5 proteins regulate the length of axial elements and telomere integrity during male mouse meiosis.

Authors:
Alberto Viera Inés Berenguer Miguel Ruiz-Torres Rocío Gómez Andrea Guajardo José Luis Barbero Ana Losada José A Suja

EMBO Rep 2020 06 14;21(6):e49273. Epub 2020 Apr 14.

Unidad de Biología Celular, Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, Spain.

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June 2020

Effects of Enteromyxum spp. (Myxozoa) infection in the regulation of intestinal E-cadherin: Turbot against gilthead sea bream.

Authors:
Paolo Ronza Itziar Estensoro Roberto Bermúdez Ana Paula Losada Gregorio Pérez-Cordón Belén G Pardo Ariadna Sitjà-Bobadilla Mª Isabel Quiroga

J Fish Dis 2020 Mar 26;43(3):337-346. Epub 2020 Jan 26.

Departamento de Anatomía, Producción Animal y Ciencias Clínicas Veterinarias, Universidade de Santiago de Compostela, Lugo, Spain.

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March 2020

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.

Authors:
Carmen Morales Miguel Ruiz-Torres Sara Rodríguez-Acebes Vanesa Lafarga Miriam Rodríguez-Corsino Diego Megías David A Cisneros Jan-Michael Peters Juan Méndez Ana Losada

J Biol Chem 2020 01 22;295(1):146-157. Epub 2019 Nov 22.

Chromosome Dynamics Group, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain

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January 2020

Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells.

Authors:
Ana Cuadrado Daniel Giménez-Llorente Aleksandar Kojic Miriam Rodríguez-Corsino Yasmina Cuartero Guillermo Martín-Serrano Gonzalo Gómez-López Marc A Marti-Renom Ana Losada

Cell Rep 2019 06;27(12):3500-3510.e4

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain. Electronic address:

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June 2019

Corrigendum: Integrating Genomic and Morphological Approaches in Fish Pathology Research: The Case of Turbot () Enteromyxosis.

Authors:
Paolo Ronza Diego Robledo Roberto Bermúdez Ana Paula Losada Belén G Pardo Paulino Martínez María Isabel Quiroga

Front Genet 2019 20;10:225. Epub 2019 Mar 20.

Departamento de Anatomía, Producción Animal y Ciencias Clínicas Veterinarias, Universidade de Santiago de Compostela, Lugo, Spain.

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March 2019

Integrating Genomic and Morphological Approaches in Fish Pathology Research: The Case of Turbot () Enteromyxosis.

Authors:
Paolo Ronza Diego Robledo Roberto Bermúdez Ana Paula Losada Belén G Pardo Paulino Martínez María Isabel Quiroga

Front Genet 2019 31;10:26. Epub 2019 Jan 31.

Departamento de Anatomía, Producción Animal y Ciencias Clínicas Veterinarias, Universidade de Santiago de Compostela, Lugo, Spain.

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January 2019

Skeletal Anomalies in Senegalese Sole ( Solea senegalensis), an Anosteocytic Boned Flatfish Species.

Authors:
Ana Manuela de Azevedo Ana Paula Losada Andrés Barreiro Sonia Vázquez María Isabel Quiroga

Vet Pathol 2019 03 3;56(2):307-316. Epub 2018 Oct 3.

1 Departamento de Anatomía, Producción Animal y Ciencias Clínicas Veterinarias, Facultade de Veterinaria, Universidade de Santiago de Compostela, Lugo, Spain.

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March 2019

First description of a natural infection with spleen and kidney necrosis virus in zebrafish.

Authors:
Roberto Bermúdez Ana Paula Losada Ana Manuela de Azevedo Jorge Guerra-Varela David Pérez-Fernández Laura Sánchez Francesc Padrós Barbara Nowak María Isabel Quiroga

J Fish Dis 2018 Jun 7. Epub 2018 Jun 7.

Department of Anatomy, Animal Production and Veterinary Clinical Sciences, Faculty of Veterinary, University of Santiago de Compostela, Lugo, Spain.

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June 2018

Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization.

Authors:
Aleksandar Kojic Ana Cuadrado Magali De Koninck Daniel Giménez-Llorente Miriam Rodríguez-Corsino Gonzalo Gómez-López François Le Dily Marc A Marti-Renom Ana Losada

Nat Struct Mol Biol 2018 06 4;25(6):496-504. Epub 2018 Jun 4.

Chromosome Dynamics Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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June 2018

Establishing and dissolving cohesion during the vertebrate cell cycle.

Authors:
Carmen Morales Ana Losada

Curr Opin Cell Biol 2018 06 10;52:51-57. Epub 2018 Feb 10.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain. Electronic address:

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June 2018

Susceptibility of Zebrafish to Vesicular Stomatitis Virus Infection.

Authors:
Jorge Guerra-Varela Maite Baz-Martínez Sabela Da Silva-Álvarez Ana Paula Losada María Isabel Quiroga Manuel Collado Carmen Rivas Laura Sánchez

Zebrafish 2018 04 5;15(2):124-132. Epub 2018 Jan 5.

1 Departamento de Zoología, Genética y Antropología Física, Facultad de Veterinaria, Universidade de Santiago de Compostela , Lugo, Spain .

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April 2018

The human Cranio Facial Development Protein 1 (Cfdp1) gene encodes a protein required for the maintenance of higher-order chromatin organization.

Authors:
Giovanni Messina Maria Teresa Atterrato Yuri Prozzillo Lucia Piacentini Ana Losada Patrizio Dimitri

Sci Rep 2017 04 3;7:45022. Epub 2017 Apr 3.

Istituto Pasteur Italia-Fondazione Cenci Bolognetti and Dipartimento di Biologia e Biotecnologie "Charles Darwin", Sapienza Università di Roma, Italy.

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April 2017

Cohesin Mutations in Cancer.

Authors:
Magali De Koninck Ana Losada

Cold Spring Harb Perspect Med 2016 Dec 1;6(12). Epub 2016 Dec 1.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid E-28029, Spain.

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December 2016

Chromatin determinants of the inner-centromere rely on replication factors with functions that impart cohesion.

Authors:
Takuya Abe Ryotaro Kawasumi Hiroshi Arakawa Tetsuya Hori Katsuhiko Shirahige Ana Losada Tatsuo Fukagawa Dana Branzei

Oncotarget 2016 10;7(42):67934-67947

IFOM, The FIRC Institute for Molecular Oncology Foundation, Milan, Italy.

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October 2016

Immunohistochemical study of inducible nitric oxide synthase and tumour necrosis factor alpha response in turbot (Scophthalmus maximus) experimentally infected with Aeromonas salmonicida subsp. salmonicida.

Authors:
Germán Coscelli Roberto Bermúdez Paolo Ronza Ana Paula Losada María Isabel Quiroga

Fish Shellfish Immunol 2016 Sep 16;56:294-302. Epub 2016 Jul 16.

Departamento de Ciencias Clínicas Veterinarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, Campus Universitario s/n, 27002, Lugo, Spain.

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September 2016

Bub1 targeting to centromeres is sufficient for Sgo1 recruitment in the absence of kinetochores.

Authors:
Samantha J Williams Ariane Abrieu Ana Losada

Chromosoma 2017 03 26;126(2):279-286. Epub 2016 Apr 26.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029, Madrid, Spain.

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March 2017

RNA-seq analysis of early enteromyxosis in turbot (Scophthalmus maximus): new insights into parasite invasion and immune evasion strategies.

Authors:
Paolo Ronza Diego Robledo Roberto Bermúdez Ana Paula Losada Belén G Pardo Ariadna Sitjà-Bobadilla María Isabel Quiroga Paulino Martínez

Int J Parasitol 2016 07 21;46(8):507-17. Epub 2016 Apr 21.

Departamento de Genética, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002 Lugo, Spain.

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July 2016

Sororin loads to the synaptonemal complex central region independently of meiotic cohesin complexes.

Authors:
Rocío Gómez Natalia Felipe-Medina Miguel Ruiz-Torres Inés Berenguer Alberto Viera Sara Pérez José Luis Barbero Elena Llano Tomoyuki Fukuda Manfred Alsheimer Alberto M Pendás Ana Losada José A Suja

EMBO Rep 2016 05 7;17(5):695-707. Epub 2016 Mar 7.

Unidad de Biología Celular, Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, Spain

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May 2016

Immunohistochemical detection and gene expression of TNFα in turbot (Scophthalmus maximus) enteromyxosis.

Authors:
Paolo Ronza Roberto Bermúdez Ana Paula Losada Ariadna Sitjà-Bobadilla Belén G Pardo María Isabel Quiroga

Fish Shellfish Immunol 2015 Nov 16;47(1):368-76. Epub 2015 Sep 16.

Departamento de Ciencias Clínicas Veterinarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002, Lugo, Spain. Electronic address:

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November 2015

Immunolocalization of tumor necrosis factor alpha in turbot (Scophthalmus maximus, L.) tissues.

Authors:
Paolo Ronza Ana Paula Losada Antonio Villamarín Roberto Bermúdez María Isabel Quiroga

Fish Shellfish Immunol 2015 Aug 7;45(2):470-6. Epub 2015 May 7.

Departamento de Ciencias Clínicas Veterinarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002, Lugo, Spain. Electronic address:

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August 2015

The contribution of cohesin-SA1 to gene expression and chromatin architecture in two murine tissues.

Authors:
Ana Cuadrado Silvia Remeseiro Osvaldo Graña David G Pisano Ana Losada

Nucleic Acids Res 2015 Mar 3;43(6):3056-67. Epub 2015 Mar 3.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain

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March 2015

The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts.

Authors:
Iva Krizaic Samantha J Williams Patricia Sánchez Miriam Rodríguez-Corsino P Todd Stukenberg Ana Losada

Nucleus 2015 8;6(2):133-43. Epub 2015 Jan 8.

a Chromosome Dynamics Group ; Molecular Oncology Program ; Spanish National Cancer Research Center (CNIO) ; Madrid , Spain.

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January 2016

RNA-seq analysis reveals significant transcriptome changes in turbot (Scophthalmus maximus) suffering severe enteromyxosis.

Authors:
Diego Robledo Paolo Ronza Peter W Harrison Ana Paula Losada Roberto Bermúdez Belén G Pardo María José Redondo Ariadna Sitjà-Bobadilla María Isabel Quiroga Paulino Martínez

BMC Genomics 2014 Dec 19;15:1149. Epub 2014 Dec 19.

Departamento de Ciencias Clínicas Veterinarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, Lugo 27002, Spain.

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December 2014

Evaluation of immune response in turbot (Psetta maxima L.) tenacibaculosis: haematological and immunohistochemical studies.

Authors:
Luis Daniel Faílde Ana Paula Losada Roberto Bermúdez Ysabel Santos M Isabel Quiroga

Microb Pathog 2014 Nov 16;76:1-9. Epub 2014 Sep 16.

Departamento de Ciencias Clínicas Veterinarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain. Electronic address:

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November 2014

Cohesin in cancer: chromosome segregation and beyond.

Authors:
Ana Losada

Nat Rev Cancer 2014 Jun;14(6):389-93

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.

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June 2014

T-cell profiling and the immunodiagnosis of latent tuberculosis infection in patients with inflammatory bowel disease.

Authors:
Miguel Arias-Guillén Sabino Riestra Ruth de Francisco Juan José Palacios José Belda Patricio Escalante Isabel Pérez-Martínez Luis M Molinos Marta Garcia-Clemente Ana Pando-Sandoval Luis Rodrigo Amador Prieto Pablo Martínez-Camblor Ana Losada Pere Casan

Inflamm Bowel Dis 2014 Feb;20(2):329-38

*Department of Respiratory Medicine, Instituto Nacional de Silicosis, Hospital Universitario Central de Asturias, Oviedo, Spain; †Department of Digestive Diseases, Hospital Universitario Central de Asturias, Oviedo, Spain; ‡Department of Microbiology, Mycobacterial Reference Unit, Hospital Universitario Central de Asturias, Oviedo, Spain; §Department of Respiratory Medicine, Hospital Arnau de Villanova, Valencia, Spain; ‖Division of Pulmonary and Critical Care Medicine and Mayo Clinic Center for Tuberculosis, Mayo Clinic, Rochester, Minnesota; ¶Department of Radiology, Hospital Universitario Central de Asturias, Oviedo; and **Oficina de Investigación Biosanitaria, Hospital Universitario Central de Asturias, Oviedo, Spain.

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February 2014

Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.

Authors:
María Carretero Miguel Ruiz-Torres Miriam Rodríguez-Corsino Isabel Barthelemy Ana Losada

EMBO J 2013 Nov 18;32(22):2938-49. Epub 2013 Oct 18.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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November 2013

Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy.

Authors:
Cristina Balbás-Martínez Ana Sagrera Enrique Carrillo-de-Santa-Pau Julie Earl Mirari Márquez Miguel Vazquez Eleonora Lapi Francesc Castro-Giner Sergi Beltran Mònica Bayés Alfredo Carrato Juan C Cigudosa Orlando Domínguez Marta Gut Jesús Herranz Núria Juanpere Manolis Kogevinas Xavier Langa Elena López-Knowles José A Lorente Josep Lloreta David G Pisano Laia Richart Daniel Rico Rocío N Salgado Adonina Tardón Stephen Chanock Simon Heath Alfonso Valencia Ana Losada Ivo Gut Núria Malats Francisco X Real

Nat Genet 2013 Dec 13;45(12):1464-9. Epub 2013 Oct 13.

Epithelial Carcinogenesis Group, Molecular Pathology Programme, CNIO (Spanish National Cancer Research Centre), Madrid, Spain.

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December 2013

Tenacibaculum maritimum infection: pathology and immunohistochemistry in experimentally challenged turbot (Psetta maxima L.).

Authors:
Luis Daniel Faílde Ana Paula Losada Roberto Bermúdez Ysabel Santos María Isabel Quiroga

Microb Pathog 2013 Dec 1;65:82-8. Epub 2013 Oct 1.

Departamento de Ciencias Clínicas Veterinarias, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002 Lugo, Spain. Electronic address:

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December 2013

Cohesin in development and disease.

Authors:
Silvia Remeseiro Ana Cuadrado Ana Losada

Development 2013 Sep;140(18):3715-8

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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September 2013

Reduction of Nipbl impairs cohesin loading locally and affects transcription but not cohesion-dependent functions in a mouse model of Cornelia de Lange Syndrome.

Authors:
Silvia Remeseiro Ana Cuadrado Shimako Kawauchi Anne L Calof Arthur D Lander Ana Losada

Biochim Biophys Acta 2013 Dec 3;1832(12):2097-102. Epub 2013 Aug 3.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain.

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December 2013

Understanding chromatin and chromosomes: from static views to dynamic thinking.

Authors:
Christian H Haering Ana Losada

EMBO Rep 2013 Feb 15;14(2):109-11. Epub 2013 Jan 15.

European Molecular Biology Laboratory, Heidelberg, Germany.

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February 2013

Cohesin, a chromatin engagement ring.

Authors:
Silvia Remeseiro Ana Losada

Curr Opin Cell Biol 2013 Feb 6;25(1):63-71. Epub 2012 Dec 6.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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February 2013

The specific contributions of cohesin-SA1 to cohesion and gene expression: implications for cancer and development.

Authors:
Ana Cuadrado Silvia Remeseiro Gonzalo Gómez-López David G Pisano Ana Losada

Cell Cycle 2012 Jun 15;11(12):2233-8. Epub 2012 Jun 15.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre, Madrid, Spain.

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June 2012

A unique role of cohesin-SA1 in gene regulation and development.

Authors:
Silvia Remeseiro Ana Cuadrado Gonzalo Gómez-López David G Pisano Ana Losada

EMBO J 2012 May 13;31(9):2090-102. Epub 2012 Mar 13.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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May 2012

Cohesin-SA1 deficiency drives aneuploidy and tumourigenesis in mice due to impaired replication of telomeres.

Authors:
Silvia Remeseiro Ana Cuadrado María Carretero Paula Martínez William C Drosopoulos Marta Cañamero Carl L Schildkraut María A Blasco Ana Losada

EMBO J 2012 May 13;31(9):2076-89. Epub 2012 Mar 13.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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May 2012

Cohesin protects genes against γH2AX Induced by DNA double-strand breaks.

Authors:
Pierre Caron Francois Aymard Jason S Iacovoni Sébastien Briois Yvan Canitrot Beatrix Bugler Laurent Massip Ana Losada Gaëlle Legube

PLoS Genet 2012 Jan 19;8(1):e1002460. Epub 2012 Jan 19.

Université de Toulouse, UPS, LBCMCP, Toulouse, France.

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January 2012

Xenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complex.

Authors:
Teresa Rivera Cristina Ghenoiu Miriam Rodríguez-Corsino Satoru Mochida Hironori Funabiki Ana Losada

EMBO J 2012 Mar 24;31(6):1467-79. Epub 2012 Jan 24.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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March 2012

Morphological and immunohistochemical characterisation of the thymus in juvenile turbot (Psetta maxima, L.).

Authors:
Fabricio Andrés Vigliano Ana Paula Losada Marta Castello Roberto Bermúdez María Isabel Quiroga

Cell Tissue Res 2011 Dec 10;346(3):407-16. Epub 2011 Dec 10.

Cátedra de Histología y Embriología, Facultad de Ciencias Veterinarias, Universidad Nacional de Rosario, Casilda, Argentina.

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December 2011

New clues to understand how CENP-A maintains centromere identity.

Authors:
Patricia Sánchez Ana Losada

Cell Div 2011 May 9;6(1):11. Epub 2011 May 9.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, Madrid, E-28029, Spain.

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May 2011

Smc5 flies solo.

Authors:
Jordi Torres-Rosell Ana Losada

Cell Cycle 2011 Mar 15;10(6):874-5. Epub 2011 Mar 15.

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March 2011

Xenopus HJURP and condensin II are required for CENP-A assembly.

Authors:
Rafael Bernad Patricia Sánchez Teresa Rivera Miriam Rodríguez-Corsino Ekaterina Boyarchuk Isabelle Vassias Dominique Ray-Gallet Alexei Arnaoutov Mary Dasso Geneviève Almouzni Ana Losada

J Cell Biol 2011 Feb 14;192(4):569-82. Epub 2011 Feb 14.

Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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February 2011

Cohesin organizes chromatin loops at DNA replication factories.

Authors:
Emmanuelle Guillou Arkaitz Ibarra Vincent Coulon Juan Casado-Vela Daniel Rico Ignacio Casal Etienne Schwob Ana Losada Juan Méndez

Genes Dev 2010 Dec;24(24):2812-22

DNA Replication Group, Spanish National Cancer Research Centre (CNIO), E-28029 Madrid, Spain.

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December 2010

Recycling cohesin rings by deacetylation.

Authors:
Teresa Rivera Ana Losada

Mol Cell 2010 Sep;39(5):657-9

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre CNIO, 28029 Madrid, Spain.

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September 2010

Cohesin ties up the genome.

Authors:
María Carretero Silvia Remeseiro Ana Losada

Curr Opin Cell Biol 2010 Dec 31;22(6):781-7. Epub 2010 Jul 31.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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December 2010

Mutations and variants in the cohesion factor genes NIPBL, SMC1A, and SMC3 in a cohort of 30 unrelated patients with Cornelia de Lange syndrome.

Authors:
Juan Pié María Concepción Gil-Rodríguez Milagros Ciero Eduardo López-Viñas María Pilar Ribate María Arnedo Matthew A Deardorff Beatriz Puisac Jesús Legarreta Juan Carlos de Karam Encarnación Rubio Inés Bueno Antonio Baldellou M Teresa Calvo Nuria Casals José Luis Olivares Ana Losada Fausto G Hegardt Ian D Krantz Paulino Gómez-Puertas Feliciano J Ramos

Am J Med Genet A 2010 Apr;152A(4):924-9

Laboratory of Clinical Genetics and Functional Genomics, Department of Pharmacology, Medical School, University of Zaragoza, Zaragoza, Spain.

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April 2010

Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion.

Authors:
Alessia Errico Claudia Cosentino Teresa Rivera Ana Losada Etienne Schwob Tim Hunt Vincenzo Costanzo

EMBO J 2009 Dec 5;28(23):3681-92. Epub 2009 Nov 5.

Genome Stability and Cell Cycle Control Groups, Cancer Research UK, Clare Hall Laboratories, South Mimms, Herts, UK.

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December 2009

Epigenetic specification of centromeres by CENP-A.

Authors:
Rafael Bernad Patricia Sánchez Ana Losada

Exp Cell Res 2009 Nov 3;315(19):3233-41. Epub 2009 Aug 3.

Molecular Oncology Programme, Spanish National Cancer Research Center (CNIO), Madrid, Spain.

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November 2009

Heterochromatin protein 1 (HP1) proteins do not drive pericentromeric cohesin enrichment in human cells.

Authors:
Angel Serrano Miriam Rodríguez-Corsino Ana Losada

PLoS One 2009 8;4(4):e5118. Epub 2009 Apr 8.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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July 2009

Shugoshin regulates cohesion by driving relocalization of PP2A in Xenopus extracts.

Authors:
Teresa Rivera Ana Losada

Chromosoma 2009 Apr 6;118(2):223-33. Epub 2008 Nov 6.

Spanish National Cancer Research Centre, Madrid, Spain.

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April 2009

The regulation of sister chromatid cohesion.

Authors:
Ana Losada

Biochim Biophys Acta 2008 Sep 24;1786(1):41-8. Epub 2008 Apr 24.

Chromosome Dynamics Group, Spanish National Cancer Research Centre, Melchor Fernández Almagro 3, Madrid E-28029, Spain.

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September 2008

Cohesin regulation: fashionable ways to wear a ring.

Authors:
Ana Losada

Chromosoma 2007 Aug 1;116(4):321-9. Epub 2007 Mar 1.

Spanish National Cancer Research Center, Melchor Fernández Almagro 3, Madrid, 28029, Spain.

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August 2007

Shugoshin and PP2A, shared duties at the centromere.

Authors:
Teresa Rivera Ana Losada

Bioessays 2006 Aug;28(8):775-9

Chromosome Dynamics Group, Spanish National Cancer Center (CNIO), Madrid, Spain.

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August 2006

Dynamic molecular linkers of the genome: the first decade of SMC proteins.

Authors:
Ana Losada Tatsuya Hirano

Genes Dev 2005 Jun;19(11):1269-87

Spanish National Cancer Center (CNIO), Madrid.

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June 2005

Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.

Authors:
Ana Losada Tomoki Yokochi Tatsuya Hirano

J Cell Sci 2005 May 26;118(Pt 10):2133-41. Epub 2005 Apr 26.

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

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May 2005

Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells.

Authors:
Takao Ono Ana Losada Michiko Hirano Michael P Myers Andrew F Neuwald Tatsuya Hirano

Cell 2003 Oct;115(1):109-21

Cold Spring Harbor Laboratory, One Bungtown Road, PO Box 100, Cold Spring Harbor, NY 11724, USA.

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October 2003

Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis.

Authors:
Ana Losada Michiko Hirano Tatsuya Hirano

Genes Dev 2002 Dec;16(23):3004-16

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.

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December 2002

Condensin and cohesin display different arm conformations with characteristic hinge angles.

Authors:
David E Anderson Ana Losada Harold P Erickson Tatsuya Hirano

J Cell Biol 2002 Feb 28;156(3):419-24. Epub 2002 Jan 28.

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA.

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February 2002

ISWI remodeling complexes in Xenopus egg extracts: identification as major chromosomal components that are regulated by INCENP-aurora B.

Authors:
David E MacCallum Ana Losada Ryuji Kobayashi Tatsuya Hirano

Mol Biol Cell 2002 Jan;13(1):25-39

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, NY 11724, USA.

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January 2002