Ana J García-Sáez

Ana J García-Sáez

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Ana J García-Sáez

Ana J García-Sáez

Publications by authors named "Ana J García-Sáez"

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MERLIN: a novel BRET-based proximity biosensor for studying mitochondria-ER contact sites.

Life Sci Alliance 2020 Jan 9;3(1). Epub 2019 Dec 9.

Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany

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http://dx.doi.org/10.26508/lsa.201900600DOI Listing
January 2020

BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL.

Cell Death Differ 2019 Oct 18;26(10):1880-1894. Epub 2018 Dec 18.

Instituto Biofisika (CSIC, UPV/EHU), Parque Científico de la UPV/EHU, Barrio Sarriena s/n, Leioa, 48940, Bizkaia, Spain.

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http://www.nature.com/articles/s41418-018-0258-5
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http://dx.doi.org/10.1038/s41418-018-0258-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748131PMC
October 2019

The Incomplete Puzzle of the BCL2 Proteins.

Cells 2019 Sep 29;8(10). Epub 2019 Sep 29.

Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen 72076, Germany.

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http://dx.doi.org/10.3390/cells8101176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830314PMC
September 2019

Quantitative analysis of super-resolved structures using ASAP.

Nat Methods 2019 08 1;16(8):711-714. Epub 2019 Jul 1.

Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41592-019-0472-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675600PMC
August 2019

AFM to Study Pore-Forming Proteins.

Methods Mol Biol 2019 ;1886:191-202

Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.

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http://link.springer.com/10.1007/978-1-4939-8894-5_10
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http://dx.doi.org/10.1007/978-1-4939-8894-5_10DOI Listing
June 2019

Dynein light chain binding determines complex formation and posttranslational stability of the Bcl-2 family members Bmf and Bim.

Cell Death Differ 2019 Jun 12. Epub 2019 Jun 12.

Institute of Medical Microbiology and Hygiene, Faculty of Medicine, Medical Center - University of Freiburg, 79104, Freiburg, Germany.

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http://dx.doi.org/10.1038/s41418-019-0365-yDOI Listing
June 2019

Quantification of the Interactions Between BCL-2 Proteins by Fluorescence Correlation Spectroscopy.

Methods Mol Biol 2019 ;1877:337-350

Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1007/978-1-4939-8861-7_20DOI Listing
May 2019

MAVS-induced mitochondrial membrane remodeling.

FEBS J 2019 Apr 8;286(8):1540-1542. Epub 2019 Apr 8.

Interfaculty Institute of Biochemistry, Eberhard Karls University, Tübingen, Germany.

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http://dx.doi.org/10.1111/febs.14822DOI Listing
April 2019

Topology of active, membrane-embedded Bax in the context of a toroidal pore.

Cell Death Differ 2018 11 5;25(10):1717-1731. Epub 2018 Sep 5.

Department of Chemistry and Biochemistry, Ruhr-University Bochum, Universitätsstr. 150, 44801, Bochum, Germany.

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http://www.nature.com/articles/s41418-018-0184-6
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http://dx.doi.org/10.1038/s41418-018-0184-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180131PMC
November 2018

Scanning Fluorescence Correlation Spectroscopy for Quantification of the Dynamics and Interactions in Tube Organelles of Living Cells.

Chemphyschem 2018 Oct 18. Epub 2018 Oct 18.

Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1002/cphc.201800705DOI Listing
October 2018

MIM through MOM: the awakening of Bax and Bak pores.

EMBO J 2018 09 22;37(17). Epub 2018 Aug 22.

Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.15252/embj.2018100340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120657PMC
September 2018

Early activation of CD95 is limited and localized to the cytotoxic synapse.

FEBS J 2018 08 19;285(15):2813-2827. Epub 2018 Jun 19.

Instituto de Investigación Médica Mercedes y Martín Ferreyra (INIMEC), CONICET-Universidad Nacional de Córdoba, Argentina.

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http://dx.doi.org/10.1111/febs.14518DOI Listing
August 2018

Drp1 polymerization stabilizes curved tubular membranes similar to those of constricted mitochondria.

J Cell Sci 2018 04 19;132(4). Epub 2018 Apr 19.

Interfaculty Institute of Biochemistry, University of Tübingen, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1242/jcs.208603DOI Listing
April 2018

Bax retrotranslocation potentiates Bcl-x's antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance.

Cell Death Dis 2018 04 1;9(4):430. Epub 2018 Apr 1.

Department of Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/s41419-018-0464-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864878PMC
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Bax, Bak and beyond - mitochondrial performance in apoptosis.

FEBS J 2018 02 4;285(3):416-431. Epub 2017 Sep 4.

Interfaculty Institute of Biochemistry, Tübingen University, Germany.

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http://dx.doi.org/10.1111/febs.14186DOI Listing
February 2018

Improving certainty in single molecule imaging.

Curr Opin Struct Biol 2017 10 5;46:24-30. Epub 2017 May 5.

Max Planck Institute for Intelligent Systems, Heisenbergstraße 3, 70569 Stuttgart, Germany; Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Straße 4, 72076 Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.sbi.2017.04.007DOI Listing
October 2017

Bcl-2 proteins: Unraveling the details of a complex and dynamic network.

Mol Cell Oncol 2018 30;5(1):e1384880. Epub 2017 Oct 30.

ZEMOS, Ruhr-University Bochum, Universitätsstrasse 150, 44801 Bochum, Germany.

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http://dx.doi.org/10.1080/23723556.2017.1384880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791859PMC
October 2017

Apoptotic foci at mitochondria: in and around Bax pores.

Philos Trans R Soc Lond B Biol Sci 2017 Aug;372(1726)

Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe Seyler Straße 4, 72076 Tübingen, Germany

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http://dx.doi.org/10.1098/rstb.2016.0217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483519PMC
August 2017

Does Ceramide Form Channels? The Ceramide-Induced Membrane Permeabilization Mechanism.

Biophys J 2017 Aug;113(4):860-868

Biofisika Institute (CSIC, UPV/EHU) and Department of Biochemistry, University of the Basque Country, Leioa, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.06.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567600PMC
August 2017

Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation.

Nat Commun 2017 07 13;8(1):73. Epub 2017 Jul 13.

Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569, Stuttgart, Germany.

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http://dx.doi.org/10.1038/s41467-017-00086-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509671PMC
July 2017

Bax and Bak Pores: Are We Closing the Circle?

Trends Cell Biol 2017 04 5;27(4):266-275. Epub 2016 Dec 5.

Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076 Tübingen, Germany; Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, Stuttgart, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2016.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898608PMC
April 2017

Determinants of BH3 Sequence Specificity for the Disruption of Bcl-xL/cBid Complexes in Membranes.

ACS Chem Biol 2017 04 17;12(4):989-1000. Epub 2017 Feb 17.

Interfaculty Institute of Biochemistry, Eberhard Karls University Tübingen , Hoppe-Seyler-Str. 4, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1021/acschembio.6b01084DOI Listing
April 2017

Necroptosis Execution Is Mediated by Plasma Membrane Nanopores Independent of Calcium.

Cell Rep 2017 04;19(1):175-187

Interfaculty Institute of Biochemistry, Tübingen University, 72076 Tübingen, Germany; Max-Planck Institute for Intelligent Systems, 70569 Stuttgart, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247173035
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http://dx.doi.org/10.1016/j.celrep.2017.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465952PMC
April 2017

Pro-apoptotic cBid and Bax exhibit distinct membrane remodeling activities: An AFM study.

Biochim Biophys Acta Biomembr 2017 Jan 15;1859(1):17-27. Epub 2016 Oct 15.

Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076 Tübingen, Germany; Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569 Stuttgart, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2016.10.007DOI Listing
January 2017

Pushing the size limit of de novo structure ensemble prediction guided by sparse SDSL-EPR restraints to 200 residues: The monomeric and homodimeric forms of BAX.

J Struct Biol 2016 07 27;195(1):62-71. Epub 2016 Apr 27.

Department of Chemistry and Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2016.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912045PMC
July 2016

MOMP in the absence of BH3-only proteins.

Genes Dev 2016 Apr;30(8):878-80

Division of Developmental Immunology, Biocenter, Medical University Innsbruck, A-6020 Innsbruck, Austria; Tyrolean Cancer Research Institute, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1101/gad.281519.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840294PMC
April 2016

Assembling the puzzle: Oligomerization of α-pore forming proteins in membranes.

Biochim Biophys Acta 2016 Mar 12;1858(3):457-466. Epub 2015 Sep 12.

Interfaculty Institute of Biochemistry (IFIB), University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.bbamem.2015.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869852PMC
March 2016

Bax assembly into rings and arcs in apoptotic mitochondria is linked to membrane pores.

EMBO J 2016 Feb 18;35(4):389-401. Epub 2016 Jan 18.

Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany Max Planck Institute for Intelligent Systems, Stuttgart, Germany

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http://dx.doi.org/10.15252/embj.201593384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755116PMC
February 2016

Membrane Disintegration Caused by the Steroid Saponin Digitonin Is Related to the Presence of Cholesterol.

Molecules 2015 Nov 9;20(11):20146-60. Epub 2015 Nov 9.

Department of Biology, Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, INF 364, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/molecules201119682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332127PMC
November 2015

Differences in activity of actinoporins are related with the hydrophobicity of their N-terminus.

Biochimie 2015 Sep 29;116:70-8. Epub 2015 Jun 29.

Center for Protein Studies, Biology Faculty, University of Havana, Havana, Cuba. Electronic address:

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http://dx.doi.org/10.1016/j.biochi.2015.06.024DOI Listing
September 2015

Bax monomers form dimer units in the membrane that further self-assemble into multiple oligomeric species.

Nat Commun 2015 Aug 14;6:8042. Epub 2015 Aug 14.

1] Membrane Biophysics, Max Planck Institute for Intelligent Systems, Heisenbergstrasse 3, 70569 Stuttgart, Germany [2] Membrane Biophysics, Interfaculty Institute of Biochemistry, University of Tuebingen, Hoppe-Seyler-Strasse 4, 72076 Tuebingen, Germany.

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http://dx.doi.org/10.1038/ncomms9042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557355PMC
August 2015

Scanning fluorescence correlation spectroscopy on biomembranes.

Methods Mol Biol 2015 ;1232:181-97

Max Planck Institute for Intelligent Systems, Heisenbergstr 3, 70569, Stuttgart, Germany,

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http://dx.doi.org/10.1007/978-1-4939-1752-5_15DOI Listing
July 2015

Atomic Force Microscopy Imaging and Force Spectroscopy of Supported Lipid Bilayers.

J Vis Exp 2015 Jul 22(101):e52867. Epub 2015 Jul 22.

Interfaculty Institute for Biochemistry; Max Planck Institute for Intelligent Systems.

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http://dx.doi.org/10.3791/52867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545161PMC
July 2015

More Than a Pore: The Interplay of Pore-Forming Proteins and Lipid Membranes.

J Membr Biol 2015 Jun 19;248(3):545-61. Epub 2015 Jun 19.

Center for Protein Studies, Faculty of Biology, Calle 25 # 455, Plaza de la Revolución, Havana, Cuba.

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http://dx.doi.org/10.1007/s00232-015-9820-yDOI Listing
June 2015

New biophysical methods to study the membrane activity of Bcl-2 proteins.

Methods Mol Biol 2014 ;1176:191-207

Membrane Biophysics, Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569, Stuttgart, Germany.

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http://dx.doi.org/10.1007/978-1-4939-0992-6_16DOI Listing
March 2015

Toxicity of an α-pore-forming toxin depends on the assembly mechanism on the target membrane as revealed by single molecule imaging.

J Biol Chem 2015 Feb 18;290(8):4856-65. Epub 2014 Dec 18.

From the Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569 Stuttgart, Germany, the German Cancer Research Center, Bioquant, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany, the Interfaculty Institute of Biochemistry, University of Tübingen, Hoppe-Seyler-Str. 4, 72076 Tübingen, Germany

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.600676
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http://dx.doi.org/10.1074/jbc.M114.600676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335225PMC
February 2015

Structural model of active Bax at the membrane.

Mol Cell 2014 Nov 30;56(4):496-505. Epub 2014 Oct 30.

Laboratory of Physical Chemistry, ETH Zurich, Vladimir-Prelog-Weg 2, 8093 Zurich, Switzerland; Fachbereich Physik, Freie Universität Berlin, Arnimallee 14, 14195 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869853PMC
November 2014

Dynamin-related protein 1 (Drp1) promotes structural intermediates of membrane division.

J Biol Chem 2014 Oct 18;289(44):30645-56. Epub 2014 Sep 18.

From the Max-Planck Institute for Intelligent Systems, 70569 Stuttgart, Germany, the Interfaculty Institute of Biochemistry, University of Tübingen, 72076 Tübingen, Germany, and

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http://dx.doi.org/10.1074/jbc.M114.575779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215243PMC
October 2014

Mitochondrial alterations in apoptosis.

Chem Phys Lipids 2014 Jul 13;181:62-75. Epub 2014 Apr 13.

German Cancer Research Center, Heidelberg, Germany; Max-Planck Institute for Intelligent Systems, Stuttgart, Germany; Interfaculty Institute of Biochemistry (IFIB), University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chemphyslip.2014.04.001DOI Listing
July 2014

Automated analysis of giant unilamellar vesicles using circular Hough transformation.

Bioinformatics 2014 Jun 18;30(12):1747-54. Epub 2014 Feb 18.

Max-Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569 Stuttgart and Interfaculty Institute for Biochemistry, University of Tübingen, Hoppe-Seyler-Straße 4, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btu102DOI Listing
June 2014

Scanning fluorescence correlation spectroscopy in model membrane systems.

Methods Mol Biol 2013 ;1033:185-205

German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-62703-487-6_13DOI Listing
March 2014

Cardiolipin effects on membrane structure and dynamics.

Langmuir 2013 Dec 10;29(51):15878-87. Epub 2013 Sep 10.

Max Planck Institute for Intelligent Systems , Heisenbergstr. 3, 70569 Stuttgart, Germany , and German Cancer Research Center , Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1021/la402669zDOI Listing
December 2013

Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size.

J Biol Chem 2013 Nov 7;288(46):33241-52. Epub 2013 Oct 7.

From the German Cancer Research Center, BioQuant, ImNeuenheimer Feld 267, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1074/jbc.M113.512087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829170PMC
November 2013

Dynamic interaction of cBid with detergents, liposomes and mitochondria.

PLoS One 2012 23;7(4):e35910. Epub 2012 Apr 23.

Department of Membrane Biochemistry, Max Planck Institute for Biochemistry, Martinsried, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0035910PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335097PMC
September 2012

Quantification of protein-protein interactions within membranes by fluorescence correlation spectroscopy.

Curr Protein Pept Sci 2011 Dec;12(8):691-8

Max-Planck for Metals Research and German Cancer Research Center, BIOQUANT, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.2174/138920311798841744DOI Listing
December 2011

All-or-none versus graded: single-vesicle analysis reveals lipid composition effects on membrane permeabilization.

Biophys J 2010 Dec;99(11):3619-28

Unidad de Biofísica, Consejo Superior de Investigaciones Científicas/University of the Basque Country, Bilbao, Spain.

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http://dx.doi.org/10.1016/j.bpj.2010.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998612PMC
December 2010

Yeast lipids can phase-separate into micrometer-scale membrane domains.

J Biol Chem 2010 Sep 20;285(39):30224-32. Epub 2010 Jul 20.

Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.123554
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http://dx.doi.org/10.1074/jbc.M110.123554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943255PMC
September 2010

Permeabilization of the outer mitochondrial membrane by Bcl-2 proteins.

Adv Exp Med Biol 2010 ;677:91-105

BIOTEC der TU Dresden, Tatzberg, Dresden, Germany.

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http://dx.doi.org/10.1007/978-1-4419-6327-7_8DOI Listing
August 2010

Stability of lipid domains.

FEBS Lett 2010 May 27;584(9):1653-8. Epub 2009 Dec 27.

Biophysics Group, BIOTEC, TU Dresden, Dresden, Germany.

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http://dx.doi.org/10.1016/j.febslet.2009.12.036DOI Listing
May 2010

Surface analysis of membrane dynamics.

Biochim Biophys Acta 2010 Apr 29;1798(4):766-76. Epub 2009 Sep 29.

Biophysics Group, BIOTEC, TU Dresden, Tatzberg 47-51, 01307 Dresden, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S000527360900334
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http://dx.doi.org/10.1016/j.bbamem.2009.09.016DOI Listing
April 2010

Confocal microscopy of giant vesicles supports the absence of HIV-1 neutralizing 2F5 antibody reactivity to plasma membrane phospholipids.

FEBS Lett 2010 Apr 17;584(8):1591-6. Epub 2010 Mar 17.

Biophysics Unit (CSIC-UPV/EHU), Biochemistry and Molecular Biology Department, University of the Basque Country, Bilbao, Spain.

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http://doi.wiley.com/10.1016/j.febslet.2010.03.021
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http://dx.doi.org/10.1016/j.febslet.2010.03.021DOI Listing
April 2010

Membrane promotes tBID interaction with BCL(XL).

Nat Struct Mol Biol 2009 Nov 11;16(11):1178-85. Epub 2009 Oct 11.

Biophysics Group, BIOTEC, TU Dresden, Dresden, Germany.

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http://dx.doi.org/10.1038/nsmb.1671DOI Listing
November 2009

Detergent-activated BAX protein is a monomer.

J Biol Chem 2009 Sep 29;284(36):23935-46. Epub 2009 Jun 29.

Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1074/jbc.M109.023853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781987PMC
September 2009

Fluorescence correlation spectroscopy for the study of membrane dynamics and protein/lipid interactions.

Methods 2008 Oct 15;46(2):116-22. Epub 2008 Jul 15.

Department of Biotec, Biophysics group, Biotechnologisches Zentrum, Tatzberg 47-51, TU Dresden, 1307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.ymeth.2008.06.011DOI Listing
October 2008

Effect of line tension on the lateral organization of lipid membranes.

J Biol Chem 2007 Nov 11;282(46):33537-44. Epub 2007 Sep 11.

Biotechnologisches Zentrum der Techische Universität Dresden, 1307 Dresden, Germany.

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http://dx.doi.org/10.1074/jbc.M706162200DOI Listing
November 2007

Single molecule techniques for the study of membrane proteins.

Appl Microbiol Biotechnol 2007 Aug 12;76(2):257-66. Epub 2007 May 12.

Biophysics Group, Biotechnologisches Zentrum (BIOTEC) der TU Dresden, Tatzberg 47-51, 01307 Dresden, Germany.

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http://link.springer.com/10.1007/s00253-007-1007-8
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http://dx.doi.org/10.1007/s00253-007-1007-8DOI Listing
August 2007

Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM.

Biophys J 2007 Jul 6;93(1):103-12. Epub 2007 Apr 6.

Biotechnologisches Zentrum der TU Dresden, Dresden, Germany.

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http://dx.doi.org/10.1529/biophysj.106.100370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914428PMC
July 2007

Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores.

FEBS J 2006 Mar;273(5):971-81

Department of Biochemistry and Molecular Biology, University of Valencia, Spain.

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http://dx.doi.org/10.1111/j.1742-4658.2006.05123.xDOI Listing
March 2006

Peptides derived from apoptotic Bax and Bid reproduce the poration activity of the parent full-length proteins.

Biophys J 2005 Jun 18;88(6):3976-90. Epub 2005 Mar 18.

Department of Biochemistry and Molecular Biology, University of Valencia, Burjassot, Spain.

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http://dx.doi.org/10.1529/biophysj.104.058008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1305629PMC
June 2005

Membrane-insertion fragments of Bcl-xL, Bax, and Bid.

Biochemistry 2004 Aug;43(34):10930-43

Departament de Bioquímica i Biologia Molecular, Universitat de València, Spain.

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http://dx.doi.org/10.1021/bi036044cDOI Listing
August 2004

Peptides in apoptosis research.

J Pept Sci 2002 Oct;8(10):543-60

Departament de Bíoquimica i Biologia Molecular, Universitat de València, E-461 00 Burjassot, Valencia, Spain.

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http://dx.doi.org/10.1002/psc.414DOI Listing
October 2002