Ana Grenha

Ana Grenha

UNVERIFIED PROFILE

Are you Ana Grenha?   Register this Author

Register author
Ana Grenha

Ana Grenha

Publications by authors named "Ana Grenha"

Are you Ana Grenha?   Register this Author

36Publications

438Reads

44Profile Views

Inhalable locust bean gum microparticles co-associating isoniazid and rifabutin: Therapeutic assessment in a murine model of tuberculosis infection.

Eur J Pharm Biopharm 2020 Feb 30;147:38-44. Epub 2019 Nov 30.

Research Institute for Medicines, (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisboa, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejpb.2019.11.009DOI Listing
February 2020

Inhalable Spray-Dried Chondroitin Sulphate Microparticles: Effect of Different Solvents on Particle Properties and Drug Activity.

Polymers (Basel) 2020 Feb 12;12(2). Epub 2020 Feb 12.

Centre for Marine Sciences, Faculdade de Ciências e Tecnologia, Universidade do Algarve, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/polym12020425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077709PMC
February 2020

Multifunctional Nanocarriers for Lung Drug Delivery.

Nanomaterials (Basel) 2020 Jan 21;10(2). Epub 2020 Jan 21.

Centre for Marine Sciences (CCMAR), Universidade do Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nano10020183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074870PMC
January 2020

Inhalable chitosan microparticles for simultaneous delivery of isoniazid and rifabutin in lung tuberculosis treatment.

Drug Dev Ind Pharm 2019 Aug 17;45(8):1313-1320. Epub 2019 May 17.

a Centre for Biomedical Research , University of Algarve , Faro , Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/03639045.2019.1608231DOI Listing
August 2019

Spray-dried fucoidan microparticles for pulmonary delivery of antitubercular drugs.

J Microencapsul 2018 Jun;35(4):392-405

a Centre for Biomedical Research , University of Algarve , Faro , Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/02652048.2018.1513089DOI Listing
June 2018

Synthesis and characterization of Locust Bean Gum derivatives and their application in the production of nanoparticles.

Carbohydr Polym 2018 Feb 16;181:974-985. Epub 2017 Nov 16.

CIQA - Centre of Research in Chemistry of Algarve, Faculty of Sciences and Technology, Campus de Gambelas, 8005-139 Faro, Portugal; Department of Chemistry and Pharmacy, Faculty of Science and Technology, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2017.11.052DOI Listing
February 2018

Microencapsulated Solid Lipid Nanoparticles as a Hybrid Platform for Pulmonary Antibiotic Delivery.

Mol Pharm 2017 09 15;14(9):2977-2990. Epub 2017 Aug 15.

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa , Av. Professor Gama Pinto, 1649-003 Lisbon, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.molpharmaceut.7b00169DOI Listing
September 2017

Dual antibiotherapy of tuberculosis mediated by inhalable locust bean gum microparticles.

Int J Pharm 2017 Aug 30;529(1-2):433-441. Epub 2017 Jun 30.

Centre for Biomedical Research (CBMR), Faculty of Sciences and Technology, University of Algarve, Faro, Portugal; Centre for Marine Sciences (CCMar), Faculty of Sciences and Technology, University of Algarve, Faro, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpharm.2017.06.088DOI Listing
August 2017

Chitosan/sulfated locust bean gum nanoparticles: In vitro and in vivo evaluation towards an application in oral immunization.

Int J Biol Macromol 2017 Mar 31;96:786-797. Epub 2016 Dec 31.

i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; INEB, Instituto de Engenharia Biomédica, Biocarrier Group, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01418130163240
Publisher Site
http://dx.doi.org/10.1016/j.ijbiomac.2016.12.076DOI Listing
March 2017

Activation of Macrophages: Establishing a Role for Polysaccharides in Drug Delivery Strategies Envisaging Antibacterial Therapy.

Curr Pharm Des 2015 ;21(33):4869-87

Centre for Biomedical Research (CBMR) - Drug Delivery Laboratory, University of Algarve, Faculty of Sciences and Technology, Campus de Gambelas, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612821666150820103910DOI Listing
August 2016

Editorial: Exploring the Role of Polysaccharides in Drug Delivery.

Authors:
Ana Grenha

Curr Pharm Des 2015 ;21(33):4773-4

Centre for Biomedical Research (CBMR) - Drug Delivery Laboratory Faculty of Sciences and Technology - University of Algarve Campus Gambelas, Building 8 Room 3.1, Lab 2.22 8005-139 Faro Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612821999150903143853DOI Listing
August 2016

Polysaccharide nanoparticles for protein and Peptide delivery: exploring less-known materials.

Adv Protein Chem Struct Biol 2015 3;98:223-61. Epub 2015 Mar 3.

CBME-Centre for Molecular and Structural Biomedicine/IBB-Institute for Biotechnology and Bioengineering, Faculty of Sciences and Technology, University of Algarve, Campus de Gambelas, Faro, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/bs.apcsb.2014.11.003DOI Listing
July 2016

Inhalable Antitubercular Therapy Mediated by Locust Bean Gum Microparticles.

Molecules 2016 May 28;21(6). Epub 2016 May 28.

Center for Biomedical Research (CBMR), Faculty of Sciences and Technology, University of Algarve, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules21060702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273308PMC
May 2016

Sulfated Seaweed Polysaccharides as Multifunctional Materials in Drug Delivery Applications.

Mar Drugs 2016 Feb 25;14(3). Epub 2016 Feb 25.

Centre for Marine Sciences, University of Algarve, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/md14030042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820297PMC
February 2016

Biocompatibility and Stability of Polysaccharide Polyelectrolyte Complexes Aimed at Respiratory Delivery.

Materials (Basel) 2015 Aug 28;8(9):5647-5670. Epub 2015 Aug 28.

CBMR-Centre for Biomedical Research, University of Algarve, Faculty of Sciences and Technology, Campus de Gambelas, Faro 8005-139, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ma8095268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512620PMC
August 2015

Hybrid nanosystems based on natural polymers as protein carriers for respiratory delivery: Stability and toxicological evaluation.

Carbohydr Polym 2015 Jun 3;123:369-80. Epub 2015 Feb 3.

CBME - Centre for Molecular and Structural Biomedicine/IBB - Institute for Biotechnology and Bioengineering, University of Algarve, Faculty of Sciences and Technology, Campus de Gambelas, 8005-139 Faro, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2015.01.048DOI Listing
June 2015

Locust bean gum as an alternative polymeric coating for embryonic stem cell culture.

Mater Sci Eng C Mater Biol Appl 2014 Jul 16;40:336-44. Epub 2014 Apr 16.

Regenerative Medicine Program, Departamento de Ciências Biomédicas e Medicina, Universidade do Algarve, Portugal; IBB - Institute for Biotechnology and Bioengineering, Centre for Molecular and Structural Biomedicine (CBME), Universidade do Algarve, Portugal; Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Campo Mártires da Pátria 130, 1169-056 Lisboa, Portugal. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.msec.2014.04.022DOI Listing
July 2014

Pullulan-based nanoparticles: future therapeutic applications in transmucosal protein delivery.

Ther Deliv 2013 Nov;4(11):1339-41

University of Algarve, Centre for Molecular & Structural Biomedicine/Institute for Biotechnology & Bioengineering, Faculty of Sciences & Technology, Campus de Gambelas, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4155/tde.13.99DOI Listing
November 2013

Natural carriers for application in tuberculosis treatment.

J Microencapsul 2013 19;30(3):295-306. Epub 2012 Sep 19.

Centre for Molecular and Structural Biomedicine/Institute for Biotechnology and Bioengineering, Faculty of Sciences and Technology, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/02652048.2012.726283DOI Listing
September 2013

Pullulan-based nanoparticles as carriers for transmucosal protein delivery.

Eur J Pharm Sci 2013 Sep 25;50(1):102-13. Epub 2013 Apr 25.

CBME - Centre for Molecular and Structural Biomedicine/IBB - Institute for Biotechnology and Bioengineering, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2013.04.018DOI Listing
September 2013

Biocompatibility of chitosan carriers with application in drug delivery.

J Funct Biomater 2012 Sep 17;3(3):615-41. Epub 2012 Sep 17.

Centre for Molecular and Structural Biomedicine (CBME), Institute for Biotechnology and Bioengineering (IBB), Faculty of Sciences and Technology, University of Algarve, Campus de Gambelas, Faro 8005-139, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jfb3030615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4030999PMC
September 2012

Locust bean gum: Exploring its potential for biopharmaceutical applications.

J Pharm Bioallied Sci 2012 Jul;4(3):175-85

CBME - Centre for Molecular and Structural Biomedicine/IBB - Institute for Biotechnology and Bioengineering, Faculty of Sciences and Technology, University of Algarve, Campus de Gambelas, Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0975-7406.99013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425165PMC
July 2012

Chitosan/carrageenan nanoparticles: effect of cross-linking with tripolyphosphate and charge ratios.

Carbohydr Polym 2012 Jun 8;89(1):282-9. Epub 2012 Mar 8.

CBME - Centre for Molecular and Structural Biomedicine/IBB - Institute for Biotechnology and Bioengineering, University of Algarve, Faculty of Sciences and Technology, Campus de Gambelas, 8005-139 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2012.03.010DOI Listing
June 2012

Chitosan nanoparticles: a survey of preparation methods.

Authors:
Ana Grenha

J Drug Target 2012 May 2;20(4):291-300. Epub 2012 Feb 2.

CBME-Centre for Molecular and Structural Biomedicine, IBB-Institute for Biotechnology and Bioengineering, University of Algarve, Campus de Gambelas, Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/1061186X.2011.654121DOI Listing
May 2012

Systemic delivery of biopharmaceuticals: Parenteral forever?

Authors:
Ana Grenha

J Pharm Bioallied Sci 2012 Apr;4(2):95

Assistant Professor in Pharmaceutics, IBB-Institute for Biotechnology and Bioengineering, Centre for Molecular and Structural Biomedicine, Faculty of Sciences and Technology - University of Algarve, Campus Gambelas, Building 8, Room 2.4, Lab 2.22, 8005-139 Faro, Portugal. E-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0975-7406.94807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3341725PMC
April 2012

The era of nanomedicine.

Authors:
Ana Grenha

J Pharm Bioallied Sci 2011 Apr;3(2):181

IBB-Institute for Biotechnology and Bioengineering, CBME-Centre for Molecular and Structural Biomedicine, Faculty of Sciences and Technology, University of Algarve, 8005-139 Faro, Portugal. E-mail:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0975-7406.80757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103910PMC
April 2011

Mucosal delivery of liposome-chitosan nanoparticle complexes.

Methods Enzymol 2009 ;465:289-312

Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0076-6879(09)65015-1DOI Listing
February 2010

Evaluation of a sunscreen during a typical beach period.

J Pharm Bioallied Sci 2010 Jan;2(1):47-50

Escola Superior de Saúde da Universidade do Algarve, Avenida Dr. Adelino da Palma Carlos, 8000-510 Faro, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4103/0975-7406.62711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146092PMC
January 2010

Microspheres containing lipid/chitosan nanoparticles complexes for pulmonary delivery of therapeutic proteins.

Eur J Pharm Biopharm 2008 May 4;69(1):83-93. Epub 2007 Nov 4.

Department of Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Santiago de Compostela, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejpb.2007.10.017DOI Listing
May 2008

Surface characterization of lipid/chitosan nanoparticles assemblies, using X-ray photoelectron spectroscopy and time-of-flight secondary ion mass spectrometry.

J Nanosci Nanotechnol 2008 Jan;8(1):358-65

Department of Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Faculty of Pharmacy, Campus Sur, 15782 Santiago de Compostela, Spain.

View Article

Download full-text PDF

Source
January 2008

Chitosan nanoparticle-loaded mannitol microspheres: structure and surface characterization.

Biomacromolecules 2007 Jul 22;8(7):2072-9. Epub 2007 Jun 22.

Department of Pharmacy and Pharmaceutical Technology, University of Santiago de Compostela, Faculty of Pharmacy, Campus Sur, 15782 Santiago de Compostela, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bm061131gDOI Listing
July 2007

Chitosan nanoparticles are compatible with respiratory epithelial cells in vitro.

Eur J Pharm Sci 2007 Jun 25;31(2):73-84. Epub 2007 Feb 25.

University of Santiago de Compostela, Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, 15782 Santiago de Compostela, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2007.02.008DOI Listing
June 2007

Microencapsulated chitosan nanoparticles for lung protein delivery.

Eur J Pharm Sci 2005 Jul-Aug;25(4-5):427-37

University of Santiago de Compostela, Pharmacy and Pharmaceutical Technology, 15782 Santiago de Compostela, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2005.04.009DOI Listing
October 2005