Ana Blas-Garcia

Ana Blas-Garcia

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Ana Blas-Garcia

Ana Blas-Garcia

Publications by authors named "Ana Blas-Garcia"

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Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases.

Redox Biol 2019 09 29;26:101263. Epub 2019 Jun 29.

Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), 28029, Madrid, Spain; Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERdem), ISCIII, 28029, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6624458PMC
September 2019

Mitophagy in human astrocytes treated with the antiretroviral drug Efavirenz: Lack of evidence or evidence of the lack.

Antiviral Res 2019 Aug 8;168:36-50. Epub 2019 May 8.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.antiviral.2019.04.015DOI Listing
August 2019

Ensuring the Consistency of Biosimilars.

Curr Pharm Des 2017 ;23(44):6733-6738

Departamento de Farmacologia, Facultad de Medicina, Universitat de Valencia, Valencia, Spain.

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http://dx.doi.org/10.2174/1381612824666171204101657DOI Listing
July 2019

Abacavir Induces Arterial Thrombosis in a Murine Model.

J Infect Dis 2018 06;218(2):228-233

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain.

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http://dx.doi.org/10.1093/infdis/jiy001DOI Listing
June 2018

Role of p62/SQSTM1 beyond autophagy: a lesson learned from drug-induced toxicity in vitro.

Br J Pharmacol 2018 02 6;175(3):440-455. Epub 2018 Jan 6.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain.

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http://dx.doi.org/10.1111/bph.14093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773949PMC
February 2018

Endoplasmic Reticulum and Mitochondria: Independent Roles and Crosstalk in Fatty Liver Diseases and Hepatic Inflammation.

Curr Pharm Des 2016 ;22(18):2607-18

Departamento de Farmacologia, Facultad de Medicina, Universitat de Valencia, Avda. Blasco Ibanez 15- 17, 46010 Valencia, Spain.

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http://dx.doi.org/10.2174/1381612822666160204120354DOI Listing
November 2017

Efavirenz: What is known about the cellular mechanisms responsible for its adverse effects.

Eur J Pharmacol 2017 Oct 8;812:163-173. Epub 2017 Jul 8.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia-Centro de Investigación Biomédica en Red-Enfermedades Hepáticas y Digestivas (CIBERehd), Valencia, Spain; FISABIO-Hospital Universitario Dr. Peset, Valencia, Spain.

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http://dx.doi.org/10.1016/j.ejphar.2017.07.016DOI Listing
October 2017

Tenofovir-induced toxicity in renal proximal tubular epithelial cells: involvement of mitochondria.

AIDS 2017 07;31(12):1679-1684

aDepartment of Pharmacology, Faculty of Medicine, University of Valencia bFISABIO cDepartment of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Valencia dServicio de Nefrología, Hospital Universitario Doctor Peset eDepartment of Nephrology, Hospital Clinico-University of Valencia fCIBERehd, Valencia, Spain.

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http://dx.doi.org/10.1097/QAD.0000000000001572DOI Listing
July 2017

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells.

Sci Rep 2017 03 3;7:42563. Epub 2017 Mar 3.

Division of Liver Diseases, Department of Medicine, Liver Cancer Program, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.1038/srep42563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335661PMC
March 2017

The purine analogues abacavir and didanosine increase acetaminophen-induced hepatotoxicity by enhancing mitochondrial dysfunction.

J Antimicrob Chemother 2016 Apr 7;71(4):916-26. Epub 2016 Jan 7.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain FISABIO-Hospital Universitario Doctor Peset, Valencia, Spain CIBERehd, Valencia, Spain.

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http://dx.doi.org/10.1093/jac/dkv424DOI Listing
April 2016

Is Autophagy Altered in the Leukocytes of Type 2 Diabetic Patients?

Antioxid Redox Signal 2015 Nov 19;23(13):1050-6. Epub 2015 Aug 19.

1 Service of Endocrinology, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region (FISABIO), University Hospital Doctor Peset , Valencia, Spain .

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http://dx.doi.org/10.1089/ars.2015.6447DOI Listing
November 2015

Is Autophagy Altered in the Leukocytes of Type 2 Diabetic Patients?

Antioxid Redox Signal 2015 Nov 19;23(13):1050-6. Epub 2015 Aug 19.

1 Service of Endocrinology, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region (FISABIO), University Hospital Doctor Peset , Valencia, Spain .

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http://dx.doi.org/10.1089/ars.2015.6447DOI Listing
November 2015

Differential effects of anti-TNF-α and anti-IL-12/23 agents on human leukocyte-endothelial cell interactions.

Eur J Pharmacol 2015 Oct 4;765:355-65. Epub 2015 Sep 4.

Departamento de Farmacología and CIBERehd, Facultad de Medicina, Universidad de Valencia, Valencia, Spain; Fundación General Universidad de Valencia, Valencia, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00142999153022
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http://dx.doi.org/10.1016/j.ejphar.2015.08.054DOI Listing
October 2015

Efavirenz alters mitochondrial respiratory function in cultured neuron and glial cell lines.

J Antimicrob Chemother 2015 Aug 29;70(8):2249-54. Epub 2015 Apr 29.

CIBERehd, Valencia, Spain Facultad de Ciencias de la Salud, Universitat Jaume I, Castellón de la Plana, Spain

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http://dx.doi.org/10.1093/jac/dkv098DOI Listing
August 2015

Involvement of nitric oxide in the mitochondrial action of efavirenz: a differential effect on neurons and glial cells.

J Infect Dis 2015 Jun 23;211(12):1953-8. Epub 2014 Dec 23.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia CIBERehd, Valencia FISABIO-Hospital Universitario Dr. Peset, Valencia, Spain.

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http://dx.doi.org/10.1093/infdis/jiu825DOI Listing
June 2015

Neuronal bioenergetics and acute mitochondrial dysfunction: a clue to understanding the central nervous system side effects of efavirenz.

J Infect Dis 2014 Nov 9;210(9):1385-95. Epub 2014 May 9.

Departamento de Farmacología, Facultad de Medicina FISABIO-Hospital Universitario Dr. Peset CIBERehd, Valencia.

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http://dx.doi.org/10.1093/infdis/jiu273DOI Listing
November 2014

Lack of mitochondrial toxicity of darunavir, raltegravir and rilpivirine in neurons and hepatocytes: a comparison with efavirenz.

J Antimicrob Chemother 2014 Nov 9;69(11):2995-3000. Epub 2014 Jul 9.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain FISABIO-Hospital Universitario Dr. Peset, Valencia, Spain CIBERehd, Valencia, Spain.

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http://dx.doi.org/10.1093/jac/dku262DOI Listing
November 2014

ER stress in human hepatic cells treated with Efavirenz: mitochondria again.

J Hepatol 2013 Oct 17;59(4):780-9. Epub 2013 Jun 17.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain; CIBERehd, Valencia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2013.06.005DOI Listing
October 2013

Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz.

Antiviral Res 2012 Jun 24;94(3):232-41. Epub 2012 Apr 24.

Departamento de Farmacología, Facultad de Medicina, Universitat de València, Valencia, Spain.

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http://dx.doi.org/10.1016/j.antiviral.2012.04.003DOI Listing
June 2012

Mitochondrial toxicity in HAART: an overview of in vitro evidence.

Curr Pharm Des 2011 ;17(20):2130-44

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Avda. Blasco Ibáñez n.15-17, 46010 Valencia, Spain.

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http://dx.doi.org/10.2174/138161211796904731DOI Listing
February 2012

Metabolomics of the effect of AMPK activation by AICAR on human umbilical vein endothelial cells.

Int J Mol Med 2012 Jan 28;29(1):88-94. Epub 2011 Sep 28.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia-CIBERehd, Valencia, Spain.

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http://dx.doi.org/10.3892/ijmm.2011.802DOI Listing
January 2012

Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition.

Trends Pharmacol Sci 2011 Dec 6;32(12):715-25. Epub 2011 Sep 6.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Avda Blasco Ibáñez n.15-17, 46010 Valencia, Spain.

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http://dx.doi.org/10.1016/j.tips.2011.07.007DOI Listing
December 2011

Mitochondria sentencing about cellular life and death: a matter of oxidative stress.

Curr Pharm Des 2011 Dec;17(36):4047-60

CIBERehd, Valencia, Spain.

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http://dx.doi.org/10.2174/138161211798764924DOI Listing
December 2011

Oxidative stress and mitochondrial impairment after treatment with anti-HIV drugs: clinical implications.

Curr Pharm Des 2011 Dec;17(36):4076-86

Departamento de Farmacologia, Universidad de Valencia, Valencia, Spain.

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http://dx.doi.org/10.2174/138161211798764951DOI Listing
December 2011

Autophagy as a rescue mechanism in efavirenz-induced mitochondrial dysfunction: a lesson from hepatic cells.

Autophagy 2011 Nov 1;7(11):1402-4. Epub 2011 Nov 1.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain.

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http://dx.doi.org/10.4161/auto.7.11.17653DOI Listing
November 2011

Compromising mitochondrial function with the antiretroviral drug efavirenz induces cell survival-promoting autophagy.

Hepatology 2011 Sep 2;54(3):1009-19. Epub 2011 Aug 2.

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia, Valencia, Spain.

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http://dx.doi.org/10.1002/hep.24459DOI Listing
September 2011

Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells.

Hepatology 2010 Jul;52(1):115-25

Departamento de Farmacología, Facultad de Medicina, Universidad de Valencia-CIBERehd, Valencia, Spain.

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http://dx.doi.org/10.1002/hep.23647DOI Listing
July 2010

Gastric antisecretory drugs induce leukocyte-endothelial cell interactions through gastrin release and activation of CCK-2 receptors.

J Pharmacol Exp Ther 2007 Oct 24;323(1):406-13. Epub 2007 Jul 24.

Centro de Investigación Biomédica en Red-Enfermedades Hépaticas y Digestivas, Facultad de Medicina, Universidad de Valencia, Avd. Blasco Ibáñez 15, 46010 Valencia, Spain.

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http://dx.doi.org/10.1124/jpet.107.122754DOI Listing
October 2007