Ana Alfirevic

Ana Alfirevic

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Ana Alfirevic

Ana Alfirevic

Publications by authors named "Ana Alfirevic"

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Trends in BRCA testing and socioeconomic deprivation.

Eur J Hum Genet 2019 Sep 3;27(9):1351-1360. Epub 2019 May 3.

Liverpool Women's Hospital NHS Foundation Trust, Liverpool, UK.

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http://dx.doi.org/10.1038/s41431-019-0424-3DOI Listing
September 2019

Genetic testing for prevention of severe drug-induced skin rash.

Cochrane Database Syst Rev 2019 07 17;7:CD010891. Epub 2019 Jul 17.

Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Centre for Personalised Medicine, Block A: Waterhouse Building, 1-5 Brownlow Street, Liverpool, UK, L69 3GE.

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http://dx.doi.org/10.1002/14651858.CD010891.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636675PMC
July 2019

Public involvement in the dissemination of the North West Coast Household Health Survey: Experiences and lessons of co-producing research together.

Health Expect 2019 Jul 29. Epub 2019 Jul 29.

Collaboration for Leadership in Applied Health Research and Care North West Coast, Liverpool, UK.

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http://dx.doi.org/10.1111/hex.12940DOI Listing
July 2019

Processes and barriers to implementation of point-of-care genotype-guided dosing of warfarin into UK outpatient anticoagulation clinics.

Pharmacogenomics 2019 Jun 3;20(8):599-608. Epub 2019 May 3.

David Weatherall Chair of Medicine, University of Liverpool & Royal Liverpool & Broadgreen University Hospitals NHS Trust, Liverpool, UK.

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http://dx.doi.org/10.2217/pgs-2019-0021DOI Listing
June 2019

Genomewide Association Study of Statin-Induced Myopathy in Patients Recruited Using the UK Clinical Practice Research Datalink.

Clin Pharmacol Ther 2019 Jun 20. Epub 2019 Jun 20.

Wolfson Centre for Personalised Medicine, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1002/cpt.1557DOI Listing
June 2019

Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study.

BMC Med 2019 04 8;17(1):76. Epub 2019 Apr 8.

MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool and The Royal Liverpool and Broadgreen University Hospitals NHS Trust, members of Liverpool Health Partners, Liverpool, UK.

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http://dx.doi.org/10.1186/s12916-019-1308-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454722PMC
April 2019

Evaluation of agreement of placental growth factor (PlGF) tests and the soluble FMS-like tyrosine kinase 1 (sFlt-1)/PlGF ratio, comparison of predictive accuracy for pre-eclampsia, and relation to uterine artery Doppler and response to aspirin.

J Matern Fetal Neonatal Med 2019 Jan 11;32(2):179-187. Epub 2017 Sep 11.

a Centre for Women's Health Research, Institute of Translational Medicine , University of Liverpool , Liverpool , UK.

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http://dx.doi.org/10.1080/14767058.2017.1373760DOI Listing
January 2019

Trastuzumab uptake in HER2-positive breast cancer patients: a systematic review and meta-analysis of observational studies.

Crit Rev Oncol Hematol 2018 Oct 3;130:92-107. Epub 2018 Aug 3.

National Institute for Health Research, Collaborations for Leadership in Applied Health Research and Care, North West Coast (NIHR CLAHRC NWC), United Kingdom; Wolfson Centre for Personalised Medicine, University of Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/j.critrevonc.2018.07.012DOI Listing
October 2018

Application of in Vitro T Cell Assay Using Human Leukocyte Antigen-Typed Healthy Donors for the Assessment of Drug Immunogenicity.

Chem Res Toxicol 2018 03 14;31(3):165-167. Epub 2018 Feb 14.

MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology , University of Liverpool , Sherrington Building, Ashton Street , Liverpool L69 3GE , England.

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http://dx.doi.org/10.1021/acs.chemrestox.8b00030DOI Listing
March 2018

Aspirin non-responsiveness in pregnant women at high-risk of pre-eclampsia.

Eur J Obstet Gynecol Reprod Biol 2018 Feb 1;221:144-150. Epub 2018 Jan 1.

Centre for Women's Health Research, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool, L8 7SS, UK.

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http://dx.doi.org/10.1016/j.ejogrb.2017.12.052DOI Listing
February 2018

HLA-A 31:01 is not associated with the development of methotrexate pneumonitis in the UK population: results from a genome-wide association study.

Ann Rheum Dis 2017 12 12;76(12):e51. Epub 2017 May 12.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2017-211512DOI Listing
December 2017

How important is aspirin adherence when evaluating effectiveness of low-dose aspirin?

Eur J Obstet Gynecol Reprod Biol 2017 Dec 3;219:1-9. Epub 2017 Oct 3.

The Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Brownlow Street, Liverpool, L69 3GL, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S03012115173046
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http://dx.doi.org/10.1016/j.ejogrb.2017.10.004DOI Listing
December 2017

An assessment of the impact of pharmacogenomics on health disparities: a systematic literature review.

Pharmacogenomics 2017 Nov 2;18(16):1541-1550. Epub 2017 Nov 2.

NIHR CLAHRC NWC Wolfson Centre for Personalised Medicine, University of Liverpool, Block A: Waterhouse Buildings, 1-5 Brownlow Street, Liverpool, L69 3GL, UK.

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http://dx.doi.org/10.2217/pgs-2017-0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694021PMC
November 2017

Cost effectiveness analysis of HLA-B*58:01 genotyping prior to initiation of allopurinol for gout.

Rheumatology (Oxford) 2017 10;56(10):1729-1739

Centre for Health Economics and Medicines Evaluation, Bangor University, Wales.

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http://dx.doi.org/10.1093/rheumatology/kex253DOI Listing
October 2017

Patient ethnicity and the risk of immune-mediated adverse drug reactions.

Authors:
Ana Alfirevic

Pharmacogenomics 2017 10 4;18(15):1375-1378. Epub 2017 Oct 4.

The Wolfson Centre for Personalised Medicine, Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Block A: Waterhouse Buildings, 1-5, Brownlow Street, Liverpool L69 3GL, UK.

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http://dx.doi.org/10.2217/pgs-2017-0124DOI Listing
October 2017

The Effect of Inhibitory Signals on the Priming of Drug Hapten-Specific T Cells That Express Distinct Vβ Receptors.

J Immunol 2017 08 7;199(4):1223-1237. Epub 2017 Jul 7.

Department of Molecular and Clinical Pharmacology, Medical Research Council Centre for Drug Safety Science, University of Liverpool, Liverpool L69 3GE, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1602029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551967PMC
August 2017

Glu83Gly Is Associated With Blunted Creatine Kinase Variation, but Not With Myalgia.

Circ Cardiovasc Genet 2017 Aug;10(4)

From the Pat McPherson Centre for Pharmacogenetics and Pharmacogenomics, Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, United Kingdom (M.K.S., A.V., C.M., R.T., F.C., E.P., J.G., A.D., C.N.A.P.); Centre for Genomic and Experimental Medicine (H.C.) and Usher Institute of Population Health Sciences and Informatics (A.D.M.), University of Edinburgh, United Kingdom; Institute of Translational Medicine, University of Liverpool, United Kingdom (M.P., A.A.); Department of Medical Sciences, Clinical Pharmacology and Science of Life Laboratory, Uppsala University, Sweden (M.W.); Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, The Netherlands (A.H.M.v.d.Z.); Department of Respiratory Medicine, Academic Medical Center, University of Amsterdam, The Netherlands (A.H.M.v.d.Z.); Brigham and Women's Hospital and Harvard Medical School, Boston, MA (P.M.R., D.I.C.).

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001737DOI Listing
August 2017

Effect of Genetic Variability in the , , and Genes on Liver mRNA Levels and Warfarin Response.

Front Pharmacol 2017 31;8:323. Epub 2017 May 31.

Wolfson Centre for Personalized Medicine, Department of Molecular and Clinical Pharmacology, The University of LiverpoolLiverpool, United Kingdom.

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http://dx.doi.org/10.3389/fphar.2017.00323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449482PMC
May 2017

Genomics of Adverse Drug Reactions.

Trends Pharmacol Sci 2017 01 10;38(1):100-109. Epub 2016 Dec 10.

Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Block A Waterhouse Buildings, 1-5 Brownlow Street, Liverpool, L69 3GL, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2016.11.003DOI Listing
January 2017

Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.

Toxicol Sci 2016 12 16;154(2):416-429. Epub 2016 Sep 16.

Department of Molecular and Clinical Pharmacology, Centre for Drug Safety Science;

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http://dx.doi.org/10.1093/toxsci/kfw177DOI Listing
December 2016

Identification of the Additional Mitochondrial Liabilities of 2-Hydroxyflutamide When Compared With its Parent Compound, Flutamide in HepG2 Cells.

Toxicol Sci 2016 10 13;153(2):341-51. Epub 2016 Jul 13.

*Department of Molecular and Clinical Pharmacology, MRC Centre for Drug Safety Science, University of Liverpool, Liverpool L69 3GE, UK.

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http://dx.doi.org/10.1093/toxsci/kfw126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036617PMC
October 2016

Pathway analysis of genetic factors associated with spontaneous preterm birth and pre-labor preterm rupture of membranes.

PLoS One 2014 29;9(9):e108578. Epub 2014 Sep 29.

Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108578PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4181300PMC
November 2015

HLA-allelotype associations with nevirapine-induced hypersensitivity reactions and hepatotoxicity: a systematic review of the literature and meta-analysis.

Pharmacogenet Genomics 2015 Apr;25(4):186-98

aWolfson Centre for Personalised Medicine, Department of Molecular and Clinical Pharmacology bDepartment of Biostatistics, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1097/FPC.0000000000000124DOI Listing
April 2015

Allele frequency net 2015 update: new features for HLA epitopes, KIR and disease and HLA adverse drug reaction associations.

Nucleic Acids Res 2015 Jan 20;43(Database issue):D784-8. Epub 2014 Nov 20.

Transplant Immunology Laboratory, Royal Liverpool and Broadgreen University Hospital, University of Liverpool, UK Institute of Infection and Global Health, University of Liverpool, UK.

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http://dx.doi.org/10.1093/nar/gku1166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383964PMC
January 2015

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

Nat Commun 2014 Sep 4;5:4757. Epub 2014 Sep 4.

1] Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina 27599, USA [2] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA [3] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden [4].

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http://dx.doi.org/10.1038/ncomms5757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155508PMC
September 2014

Is the interleukin 8 promoter polymorphism rs4073/-251T >A associated with Clostridium difficile infection?

Clin Infect Dis 2014 Jun 14;58(12):e148-51. Epub 2014 Mar 14.

Wolfson Centre for Personalised Medicine, University of Liverpool Royal Liverpool and Broadgreen University Hospital NHS Trust.

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http://dx.doi.org/10.1093/cid/ciu152DOI Listing
June 2014

Pharmacogenomics: Current State-of-the-Art.

Genes (Basel) 2014 May 26;5(2):430-43. Epub 2014 May 26.

Wolfson Centre for Personalised Medicine, Department of Molecular and Clinical Pharmacology, University of Liverpool, Block A Waterhouse Buildings, 1-5 Brownlow Street, Liverpool, L69 3GL, UK.

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http://dx.doi.org/10.3390/genes5020430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094941PMC
May 2014

Pharmacogenetics of antiepileptic drug-induced hypersensitivity.

Pharmacogenomics 2014 Apr;15(6):857-68

The Wolfson Centre for Personalised Medicine, Department of Molecular & Clinical Pharmacology, University of Liverpool, Block A: Waterhouse Buildings, 1-5 Brownlow Street, Liverpool, L69 3GL, UK.

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http://dx.doi.org/10.2217/pgs.14.65DOI Listing
April 2014

HLA restriction of carbamazepine-specific T-Cell clones from an HLA-A*31:01-positive hypersensitive patient.

Chem Res Toxicol 2014 Feb 31;27(2):175-7. Epub 2014 Jan 31.

Department of Molecular and Clinical Pharmacology, University of Liverpool , Sherrington Building, Ashton Street, Liverpool L69 3GE, England.

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http://dx.doi.org/10.1021/tx400460wDOI Listing
February 2014

ABCB1 single nucleotide polymorphisms (1236C>T, 2677G>T, and 3435C>T) do not affect transport activity of human P-glycoprotein.

Pharmacogenet Genomics 2013 Jun;23(6):314-23

Department of Molecular and Clinical Pharmacology, The Wolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1097/FPC.0b013e328360d10cDOI Listing
June 2013

Institutional profile: the Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK.

Pharmacogenomics 2013 Jun;14(8):861-7

Department of Molecular & Clinical Pharmacology, University of Liverpool, Block A: Waterhouse Buildings, 1-5 Brownlow Street, Liverpool L69 3GL, UK.

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http://dx.doi.org/10.2217/pgs.13.73DOI Listing
June 2013

T-cells from HLA-B*57:01+ human subjects are activated with abacavir through two independent pathways and induce cell death by multiple mechanisms.

Chem Res Toxicol 2013 May 12;26(5):759-66. Epub 2013 Apr 12.

MRC Centre for Drug Safety Science, Department of Pharmacology, University of Liverpool , Sherrington Building, Ashton Street, Liverpool L69 3GE, England.

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http://dx.doi.org/10.1021/tx400060pDOI Listing
May 2013

Explanation for HLA-B*57:01-linked immune-mediated abacavir-induced hypersensitivity.

Pharmacogenomics 2012 Nov;13(14):1567-9

The Wolfson Centre for Personalised Medicine, Department of Molecular & Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Block A Waterhouse Buildings, 1-5 Brownlow Street, Liverpool L69 3GL, UK.

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http://dx.doi.org/10.2217/pgs.12.146DOI Listing
November 2012

In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers.

Genome Med 2012 Jun 25;4(6):51. Epub 2012 Jun 25.

Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, The Waterhouse Building, Brownlow Street 1-5, Liverpool, L69 3GL, UK.

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http://dx.doi.org/10.1186/gm350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698530PMC
June 2012

Lamotrigine is a substrate for OCT1 in brain endothelial cells.

Biochem Pharmacol 2012 Mar 29;83(6):805-14. Epub 2011 Dec 29.

Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1016/j.bcp.2011.12.032DOI Listing
March 2012

Pharmacogenomics and personalized medicine: the plunge into next-generation sequencing.

Genome Med 2011 Dec 28;3(12):78. Epub 2011 Dec 28.

Department of Medical Sciences, Clinical Pharmacology, Uppsala University, Uppsala University Hospital, entrance 61, SE-751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1186/gm294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334543PMC
December 2011

Metabolic acidosis with topiramate and zonisamide: an assessment of its severity and predictors.

Pharmacogenet Genomics 2011 May;21(5):297-302

Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1097/FPC.0b013e3283441b95DOI Listing
May 2011

Pharmacogenetics and pharmacogenomics: practical applications in routine medical practice.

Genome Med 2010 Sep 21;2(9):69. Epub 2010 Sep 21.

Utrecht Institute for Pharmaceutical Sciences, Division of Pharmacoepidemiology and Pharmacotherapy, Faculty of Science, Utrecht University, Sorbonnelaan 16, PO Box 80082, 3508 TB Utrecht, the Netherlands.

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http://dx.doi.org/10.1186/gm190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092120PMC
September 2010

Drug-induced hypersensitivity reactions and pharmacogenomics: past, present and future.

Pharmacogenomics 2010 Apr;11(4):497-9

The Wolfson Centre for Personalised Medicine, Department of Pharmacology, University of Liverpool, Block A, Waterhouse Buildings, 1-5 Brownlow Street, Liverpool, L69 3GL, UK.

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https://www.futuremedicine.com/doi/10.2217/pgs.10.12
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http://dx.doi.org/10.2217/pgs.10.12DOI Listing
April 2010

Pharmacogenetics in reproductive and perinatal medicine.

Pharmacogenomics 2010 Jan;11(1):65-79

Department of Pharmacology & Therapeutics, Sherrington Building, Ashton Street, University of Liverpool, Liverpool, Merseyside, L69 3GE, UK.

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http://dx.doi.org/10.2217/pgs.09.153DOI Listing
January 2010

Effects of CYP4F2 genetic polymorphisms and haplotypes on clinical outcomes in patients initiated on warfarin therapy.

Pharmacogenet Genomics 2009 Oct;19(10):781-9

Department of Pharmacology and Therapeutics, The University of Liverpool, Royal Liverpool University Hospital, UK.

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https://insights.ovid.com/crossref?an=01213011-200910000-000
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http://dx.doi.org/10.1097/FPC.0b013e3283311347DOI Listing
October 2009

TNF, LTA, HSPA1L and HLA-DR gene polymorphisms in HIV-positive patients with hypersensitivity to cotrimoxazole.

Pharmacogenomics 2009 Apr;10(4):531-40

Department of Pharmacology & Therapeutics, University of Liverpool, Sherrington Building, Ashton Street, Liverpool, Merseyside, L69 3GE, UK.

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http://dx.doi.org/10.2217/pgs.09.6DOI Listing
April 2009

Pharmacogenetics and pharmacogenomics: adverse drug reactions.

Pharmacogenomics 2008 Oct;9(10):1397-401

Center for Medical Statistics and Health Evaluation, Faculty of Medicine, University of Liverpool, Liverpool L693GS, UK.

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http://dx.doi.org/10.2217/14622416.9.10.1397DOI Listing
October 2008

Adverse drug reactions and pharmacogenomics: recent advances.

Per Med 2008 Jan;5(1):11-23

The University of Liverpool, Department of Pharmacology & Therapeutics, Sherrington Building, Ashton Street, Liverpool, Merseyside, L69 3GE, UK.

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http://dx.doi.org/10.2217/17410541.5.1.11DOI Listing
January 2008

Tacrine-induced liver damage: an analysis of 19 candidate genes.

Pharmacogenet Genomics 2007 Dec;17(12):1091-100

Department of Pharmacology and Therapeutics, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool, UK.

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http://pdfs.journals.lww.com/jpharmacogenetics/2007/12000/9.
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/FPC.0b013e3282f1f12bDOI Listing
December 2007

Molecular and genetic association of interleukin-6 in tacrine-induced hepatotoxicity.

Pharmacogenet Genomics 2007 Nov;17(11):961-72

Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1097/FPC.0b013e3282f00919DOI Listing
November 2007

The 2nd International Drug Hypersensitivity Meeting 18 - 21 April 2006, The University of Liverpool, Liverpool, UK.

Expert Opin Drug Saf 2006 Sep;5(5):729-34

University of Liverpool, Department of Pharmacology and Therapeutics, The Sherrington Buildings, Ashton Street, Liverpool L69 3GE, UK.

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http://www.tandfonline.com/doi/full/10.1517/14740338.5.5.729
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http://dx.doi.org/10.1517/14740338.5.5.729 DOI Listing
September 2006

HLA-B locus in Caucasian patients with carbamazepine hypersensitivity.

Pharmacogenomics 2006 Sep;7(6):813-8

Department of Pharmacology & Therapeutics, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool, L69 3GE, UK.

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https://www.futuremedicine.com/doi/10.2217/14622416.7.6.813
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http://dx.doi.org/10.2217/14622416.7.6.813DOI Listing
September 2006

Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster.

Pharmacogenet Genomics 2006 Apr;16(4):287-96

Department of Pharmacology and Therapeutics, The University of Liverpool, Sherrington Building, Ashton Street, Liverpool, UK.

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http://dx.doi.org/10.1097/01.fpc.0000189800.88596.7aDOI Listing
April 2006

Cost-effectiveness analysis of HLA B*5701 genotyping in preventing abacavir hypersensitivity.

Pharmacogenetics 2004 Jun;14(6):335-42

Department of Pharmacology and Therapeutics, University of Liverpool, Liverpool, L69 3GE, UK.

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June 2004

Slow acetylator phenotype and genotype in HIV-positive patients with sulphamethoxazole hypersensitivity.

Br J Clin Pharmacol 2003 Feb;55(2):158-65

Department of Pharmacology and Therapeutics, The University of Liverpool, Liverpool, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1894729PMC
http://dx.doi.org/10.1046/j.1365-2125.2003.01754.xDOI Listing
February 2003

TNF-alpha promoter region gene polymorphisms in HIV-positive patients with lipodystrophy.

AIDS 2002 Oct;16(15):2013-8

Department of Pharmacology, The University of Liverpool, Ashton Street, Liverpool, UK.

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http://dx.doi.org/10.1097/00002030-200210180-00005DOI Listing
October 2002