Amy Q Wang

Amy Q Wang

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Amy Q Wang

Amy Q Wang

Publications by authors named "Amy Q Wang"

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24Publications

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Quantitation of cytidine-5'-monophospho-N-acetylneuraminic acid in human leukocytes using LC-MS/MS: method development and validation.

Biomed Chromatogr 2019 Nov 6:e4735. Epub 2019 Nov 6.

Therapeutic Development Branch, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.

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http://dx.doi.org/10.1002/bmc.4735DOI Listing
November 2019

Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors.

Bioorg Med Chem Lett 2018 11 6;28(20):3356-3362. Epub 2018 Sep 6.

National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Bethesda, MD 20892-3370, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X183073
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http://dx.doi.org/10.1016/j.bmcl.2018.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218249PMC
November 2018

Discovery and lead identification of quinazoline-based BRD4 inhibitors.

Bioorg Med Chem Lett 2018 11 31;28(21):3483-3488. Epub 2018 Aug 31.

National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.08.039DOI Listing
November 2018

Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine.

J Psychopharmacol 2018 Nov 29:269881118812095. Epub 2018 Nov 29.

1 Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/0269881118812095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541551PMC
November 2018

Quantification of cyclocreatine in mouse and rat plasma using hydrophilic-interaction ultra-performance liquid chromatography-tandem mass spectrometry.

J Pharm Biomed Anal 2017 Oct 31;145:629-633. Epub 2017 Jul 31.

Therapeutics for Rare and Neglected Diseases, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD 20850, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S07317085173008
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http://dx.doi.org/10.1016/j.jpba.2017.07.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5587398PMC
October 2017

Safety, pharmacokinetics and sialic acid production after oral administration of N-acetylmannosamine (ManNAc) to subjects with GNE myopathy.

Mol Genet Metab 2017 09 26;122(1-2):126-134. Epub 2017 Apr 26.

Therapeutics for Rare and Neglected Diseases, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD 20892, USA; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2017.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949875PMC
September 2017

An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software.

Drug Metab Dispos 2016 10 14;44(10):1653-61. Epub 2016 Jul 14.

Division of Preclinical Innovation, National Center for Advancing Translational Sciences, Rockville Maryland (P.S, E.K, D-T.N, A Q.W, A.Z, J.M, A.S, X.X.); Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer. Groton, Connecticut (R.S.O.); and Department of Drug Metabolism and Pharmacokinetics, Genentech Inc., South San Francisco, California (C.E.C.A.H)

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034701PMC
http://dx.doi.org/10.1124/dmd.116.072017DOI Listing
October 2016

Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.

PLoS Pathog 2016 06 23;12(6):e1005717. Epub 2016 Jun 23.

Department of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919066PMC
June 2016

Discovery, Optimization, and Characterization of Novel Chlorcyclizine Derivatives for the Treatment of Hepatitis C Virus Infection.

J Med Chem 2016 Feb 1;59(3):841-53. Epub 2016 Feb 1.

Division of Pre-Clinical Innovations, National Center for Advancing Translational Sciences, National Institutes of Health , 9800 Medical Center Drive, Rockville, Maryland 20850, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.5b00752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753534PMC
February 2016