Publications by authors named "Amy Lum"

32Publications

SWI/SNF-deficiency defines highly aggressive undifferentiated endometrial carcinoma.

J Pathol Clin Res 2020 Oct 30. Epub 2020 Oct 30.

Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital and University of Alberta, Edmonton, Canada.

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October 2020

TRIM25 promotes Capicua degradation independently of ERK in the absence of ATXN1L.

BMC Biol 2020 10 28;18(1):154. Epub 2020 Oct 28.

Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

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October 2020

Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).

Authors:
Aline Talhouk Joshy George Chen Wang Timothy Budden Tuan Zea Tan Derek S Chiu Stefan Kommoss Huei San Leong Stephanie Chen Maria P Intermaggio Blake Gilks Tayyebeh M Nazeran Mila Volchek Wafaa Elatre Rex C Bentley Janine Senz Amy Lum Veronica Chow Hanwei Sudderuddin Robertson Mackenzie Samuel C Y Leong Geyi Liu Dustin Johnson Billy Chen Aocs Group Jennifer Alsop Susana N Banerjee Sabine Behrens Clara Bodelon Alison H Brand Louise Brinton Michael E Carney Yoke-Eng Chiew Kara L Cushing-Haugen Cezary Cybulski Darren Ennis Sian Fereday Renée T Fortner Jesús García-Donas Aleksandra Gentry-Maharaj Rosalind Glasspool Teodora Goranova Casey S Greene Paul Haluska Holly R Harris Joy Hendley Brenda Y Hernandez Esther Herpel Mercedes Jimenez-Linan Chloe Karpinskyj Scott H Kaufmann Gary L Keeney Catherine J Kennedy Martin Köbel Jennifer M Koziak Melissa C Larson Jenny Lester Liz-Anne Lewsley Jolanta Lissowska Jan Lubiński Hugh Luk Geoff Macintyre Sven Mahner Iain A McNeish Janusz Menkiszak Nikilyn Nevins Ana Osorio Oleg Oszurek José Palacios Samantha Hinsley Celeste L Pearce Malcolm C Pike Anna M Piskorz Isabelle Ray-Coquard Valerie Rhenius Cristina Rodriguez-Antona Raghwa Sharma Mark E Sherman Dilrini De Silva Naveena Singh Peter Sinn Dennis Slamon Honglin Song Helen Steed Euan A Stronach Pamela J Thompson Aleksandra Tołoczko Britton Trabert Nadia Traficante Chiu-Chen Tseng Martin Widschwendter Lynne R Wilkens Stacey J Winham Boris Winterhoff Alicia Beeghly-Fadiel Javier Benitez Andrew Berchuck James D Brenton Robert Brown Jenny Chang-Claude Georgia Chenevix-Trench Anna deFazio Peter A Fasching María J García Simon A Gayther Marc T Goodman Jacek Gronwald Michelle J Henderson Beth Y Karlan Linda E Kelemen Usha Menon Sandra Orsulic Paul D P Pharoah Nicolas Wentzensen Anna H Wu Joellen M Schildkraut Mary Anne Rossing Gottfried E Konecny David G Huntsman Ruby Yun-Ju Huang Ellen L Goode Susan J Ramus Jennifer A Doherty David D Bowtell Michael S Anglesio

Clin Cancer Res 2020 Oct 17;26(20):5411-5423. Epub 2020 Jun 17.

British Columbia's Gynecological Cancer Research Program (OVCARE), BC Cancer, Vancouver General Hospital, and University of British Columbia, Vancouver, British Columbia, Canada.

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October 2020

Molecular subtypes of clear cell carcinoma of the endometrium: Opportunities for prognostic and predictive stratification.

Gynecol Oncol 2020 07 21;158(1):3-11. Epub 2020 Apr 21.

Department of Obstetrics and Gynecology, Division of Gynecology Oncology, University of British Columbia, Vancouver, BC, Canada; BC Cancer Agency, Vancouver, BC, Canada. Electronic address:

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July 2020

Characterisation of isocitrate dehydrogenase 1/isocitrate dehydrogenase 2 gene mutation and the d-2-hydroxyglutarate oncometabolite level in dedifferentiated chondrosarcoma.

Histopathology 2020 Apr 10;76(5):722-730. Epub 2020 Mar 10.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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April 2020

Molecular classification defines outcomes and opportunities in young women with endometrial carcinoma.

Gynecol Oncol 2019 06 25;153(3):487-495. Epub 2019 Mar 25.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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June 2019

Novel EPC1 gene fusions in endometrial stromal sarcoma.

Genes Chromosomes Cancer 2018 11 24;57(11):598-603. Epub 2018 Aug 24.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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November 2018

Transcriptomic analysis of CIC and ATXN1L reveal a functional relationship exploited by cancer.

Oncogene 2019 01 9;38(2):273-290. Epub 2018 Aug 9.

Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

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January 2019

DICER1 hot-spot mutations in ovarian gynandroblastoma.

Histopathology 2018 Aug 5;73(2):306-313. Epub 2018 Jun 5.

Institute of Pathology, Medizin Campus Bodensee, Friedrichshafen, Germany.

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August 2018

LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers.

Gynecol Oncol 2017 12 9;147(3):642-647. Epub 2017 Oct 9.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Molecular Oncology, BC Cancer Agency, Vancouver, BC, Canada. Electronic address:

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December 2017

Cancer-Associated Mutations in Endometriosis without Cancer.

N Engl J Med 2017 05;376(19):1835-1848

From the Departments of Obstetrics and Gynaecology (M.S.A., C.A., C.W., P.J.Y., D.G.H.) and Pathology and Laboratory Medicine (M.S.A., T.M.N., J. Senz, B.T.-C., C.B.G., D.G.H.), University of British Columbia, the Department of Anatomical Pathology, Vancouver General Hospital (T.M.N., H.M.H., J.H., V.L., B.T.-C., A.W., C.B.G., D.G.H.), the Department of Molecular Oncology, British Columbia Cancer Agency (H.M.H., A.L., V.L., N.B., D.G.H.), and the BC Women's Centre for Pelvic Pain and Endometriosis, BC Women's Hospital and Health Centre (F.W., N.O., C.A., C.W., P.J.Y.) - all in Vancouver, BC, Canada; the Department of Oncology (N.P., C.T., K.W.K., L.D., T.-L.W., B.V., I.-M.S.) and Ludwig Center (N.P., Y.W., J.D.C., M.Z., M.P., W.M., A.M., K.W.K., L.D., B.V.), Sidney Kimmel Comprehensive Cancer Center, the Departments of Pathology (N.P., A.A., M.N., L.D.W., T.-L.W., B.V., I.-M.S.) and Gynecology and Obstetrics (J. Segars, I.-M.S.), Johns Hopkins Medical Institutions, Personal Genome Diagnostics (S.J.), and Johns Hopkins University Howard Hughes Medical Institute (B.V.) - all in Baltimore; the Department of Pathology, Seirei Mikatahara Hospital (A.A., H.O.), and the Department of Tumor Pathology, Hamamatsu University School of Medicine (A.A.), Hamamatsu, and the Department of Molecular Pathology, Hiroshima University School of Medicine, Hiroshima (A.A.) - all in Japan; the Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands (M.N.); the Departments of Obstetrics and Gynecology (T.S.) and Pathology (R.A., A.H.), Lenox Hill Hospital-Northwell Health (Hofstra University), New York; and the Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Tao-Yuan City, Taiwan (R.-C.W.).

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May 2017

Confirmation of ProMisE: A simple, genomics-based clinical classifier for endometrial cancer.

Cancer 2017 03 6;123(5):802-813. Epub 2017 Jan 6.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, Vancouver, British Columbia, Canada.

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March 2017

FOXL2 402C>G Mutation Can Be Identified in the Circulating Tumor DNA of Patients with Adult-Type Granulosa Cell Tumor.

J Mol Diagn 2017 01 1;19(1):126-136. Epub 2016 Nov 1.

Department of Pathology and Laboratory Medicine, University of British Columbia, and the Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada. Electronic address:

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January 2017

Molecular classification of endometrial carcinoma on diagnostic specimens is highly concordant with final hysterectomy: Earlier prognostic information to guide treatment.

Gynecol Oncol 2016 10 14;143(1):46-53. Epub 2016 Jul 14.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, 2775 Laurel St., 6th Floor, Vancouver, British Columbia V5Z 1M9, Canada. Electronic address:

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October 2016

ETV6-NTRK3 Is Expressed in a Subset of ALK-Negative Inflammatory Myofibroblastic Tumors.

Am J Surg Pathol 2016 08;40(8):1051-61

*Department of Pathology, Vancouver General Hospital §Genome Sciences Center ∥British Columbia Cancer Agency ¶British Columbia Children's Hospital #Department of Pathology, University of British Columbia, Vancouver, BC **Department of Pathology, Royal Alexandra Hospital, Edmonton, AB, Canada †Department of Pathology, King Abdulaziz Medical City, Riyadh, Saudi Arabia ‡Department of Pathology, Kuwait University, Kuwait.

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August 2016

Somatic mosaicism for the p.His1047Arg mutation in PIK3CA in a girl with mesenteric lipomatosis.

Am J Med Genet A 2014 Sep 5;164A(9):2360-4. Epub 2014 Jun 5.

Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; Child and Family Research Institute, British Columbia Children's Hospital, Vancouver, BC, Canada.

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September 2014

Diagnostic value of next-generation sequencing in an unusual sphenoid tumor.

Oncologist 2014 Jun 7;19(6):623-30. Epub 2014 May 7.

Centre for Translational and Applied Genomics, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada; Division of Oncology/Hematology/BMT, Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medical Oncology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada

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June 2014

Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer.

BMC Cancer 2010 Feb 11;10:40. Epub 2010 Feb 11.

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143-0414, USA.

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February 2010

A key developmental regulator controls the synthesis of the antibiotic erythromycin in Saccharopolyspora erythraea.

Proc Natl Acad Sci U S A 2008 Aug 6;105(32):11346-51. Epub 2008 Aug 6.

Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.

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August 2008

Pvt1-encoded microRNAs in oncogenesis.

Retrovirology 2008 Jan 14;5. Epub 2008 Jan 14.

Department of Microbiology and Immunology, University of California, San Francisco, CA 94143-0414, USA.

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January 2008

Retroviral activation of the mir-106a microRNA cistron in T lymphoma.

Retrovirology 2007 Jan 25;4. Epub 2007 Jan 25.

Picobella, L.L.C., Burlingame, CA, 94010, USA.

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January 2007

Reverse engineering of industrial pharmaceutical-producing actinomycete strains using DNA microarrays.

Metab Eng 2004 Jul;6(3):186-96

Department of Chemical Engineering, MC 5025, Stanford University, CA 94305, USA.

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July 2004