Amy J Wagers

Amy J Wagers

UNVERIFIED PROFILE

Are you Amy J Wagers?   Register this Author

Register author
Amy J Wagers

Amy J Wagers

Publications by authors named "Amy J Wagers"

Are you Amy J Wagers?   Register this Author

99Publications

3046Reads

44Profile Views

Steady-state and regenerative hematopoiesis occurs normally in mice in the absence of GDF11.

Blood 2019 11;134(20):1712-1716

Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood.2019002066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856987PMC
November 2019

Analysis of Cre-mediated genetic deletion of in cardiomyocytes of young mice.

Am J Physiol Heart Circ Physiol 2019 07 24;317(1):H201-H212. Epub 2019 May 24.

Department of Stem Cell and Regenerative Biology and the Harvard Stem Cell Institute, Harvard University , Cambridge, Massachusetts.

View Article

Download full-text PDF

Source
https://www.physiology.org/doi/10.1152/ajpheart.00615.2018
Publisher Site
http://dx.doi.org/10.1152/ajpheart.00615.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692736PMC
July 2019

In Situ Modification of Tissue Stem and Progenitor Cell Genomes.

Cell Rep 2019 04;27(4):1254-1264.e7

Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA 02115, USA; Joslin Diabetes Center, Boston, MA 02215, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2019.03.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858480PMC
April 2019

Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors.

EMBO J 2018 12 16;37(24). Epub 2018 Nov 16.

Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.2018100409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293338PMC
December 2018

What's in a (Sub)strain?

Stem Cell Reports 2018 08;11(2):303-305

Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA; Joslin Diabetes Center, Boston, MA 02215, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2018.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094162PMC
August 2018

Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors.

Stem Cell Reports 2018 05;10(5):1505-1521

Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Cancer Center, Massachusetts General Hospital, Boston, MA 02114, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2018.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995754PMC
May 2018

Established cell surface markers efficiently isolate highly overlapping populations of skeletal muscle satellite cells by fluorescence-activated cell sorting.

Skelet Muscle 2016 8;6:35. Epub 2016 Nov 8.

Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA 02138 USA.

View Article

Download full-text PDF

Source
http://skeletalmusclejournal.biomedcentral.com/articles/10.1
Publisher Site
http://dx.doi.org/10.1186/s13395-016-0106-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100091PMC
October 2017

Organism-Level Analysis of Vaccination Reveals Networks of Protection across Tissues.

Cell 2017 Oct 21;171(2):398-413.e21. Epub 2017 Sep 21.

Faculty of Arts & Sciences Center for Systems Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2017.08.024DOI Listing
October 2017

Age-associated NF-κB signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function.

Aging (Albany NY) 2016 11;8(11):2871-2896

Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.101098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191876PMC
November 2016

The Vitamin D Receptor Regulates Tissue Resident Macrophage Response to Injury.

Endocrinology 2016 Oct 15;157(10):4066-4075. Epub 2016 Aug 15.

Endocrine Unit (L.S., G.P., H.Z., H.F.L., M.B.D.) and Department of Pathology (R.M.N.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114; and Department of Stem Cell and Regenerative Biology (C.M., C.D., A.J.W.), Harvard University and Harvard Stem Cell Institute, Cambridge, Massachusetts 02138.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2016-1474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045513PMC
October 2016

A multifunctional AAV-CRISPR-Cas9 and its host response.

Nat Methods 2016 10 5;13(10):868-74. Epub 2016 Sep 5.

Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth.3993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374744PMC
October 2016

Phosphoproteomic profiling of mouse primary HSPCs reveals new regulators of HSPC mobilization.

Blood 2016 09 30;128(11):1465-74. Epub 2016 Jun 30.

Joslin Diabetes Center, Boston, MA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025898PMC
http://dx.doi.org/10.1182/blood-2016-05-711424DOI Listing
September 2016

Aging and Rejuvenation: Insights from Rusty Gage, Leonard Guarente, and Amy Wagers.

Trends Mol Med 2016 08 5;22(8):633-634. Epub 2016 Jul 5.

Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmed.2016.06.011DOI Listing
August 2016

Developmental regulation of myeloerythroid progenitor function by the Lin28b-let-7-Hmga2 axis.

J Exp Med 2016 07 11;213(8):1497-512. Epub 2016 Jul 11.

Stem Cell Transplantation Program, Stem Cell Program, Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, MA 02215 Harvard Stem Cell Institute, Cambridge, MA 02138 Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115 Howard Hughes Medical Institute, Boston, MA 02115 Division of Hematology, Brigham and Women's Hospital, Boston, MA 02115 Manton Center for Orphan Disease Research, Boston, MA 02115

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20151912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986532PMC
July 2016

Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease.

Nat Rev Mol Cell Biol 2016 05 9;17(5):267-79. Epub 2016 Mar 9.

Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, Massachusetts 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrm.2016.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918817PMC
May 2016

Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation.

Circ Res 2016 Apr;118(7):1125-41; discussion 1142

From the Department of Molecular Genetics, College of Medicine, University of Cincinnati, OH (R.G.W., T.B.T.); Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA (T.P., L.K., S.M.B., J.O., S.W., L.L.R., A.J.W., R.T.L.); Department of Neuroscience, Institut Pasteur, Paris, France (L.K.); Cardiovascular Division (T.P.), Department of Medicine, Brigham Regenerative Medicine Center, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (Y.W.F., R.T.L.); Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, MA (J.O., S.W., A.J.W.); Division of Cardiology, Universitäres Herzzentrum, Zürich, Switzerland (B.H.); Department of Medicine, University of California, San Francisco (B.H., P.G.); and Division of Cardiology, San Francisco General Hospital, CA (P.G.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.116.308391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818972PMC
April 2016

Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells.

Immunity 2016 Feb 9;44(2):355-67. Epub 2016 Feb 9.

Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA; Evergrande Center for Immunologic Diseases, Harvard Medical School and Brigham and Women's Hospital, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2016.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764071PMC
February 2016

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Cell 2016 Feb;164(5):884-95

Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2016.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819986PMC
February 2016

Hedgehog-driven myogenic tumors recapitulate skeletal muscle cellular heterogeneity.

Exp Cell Res 2016 Jan 13;340(1):43-52. Epub 2015 Oct 13.

Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2015.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718790PMC
January 2016

Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.

Circ Res 2016 Jan 21;118(1):29-37. Epub 2015 Oct 21.

From the Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA (T.P., A.V., P.Y., C.M.-T., A.U., F.S.L., J.R.P., M.C., J.G., R.M.T., E.G., A.J.W., Y.W.F., R.T.L.); Brigham Regenerative Medicine Center and Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA (T.P., A.V., P.Y., C.M.-T., A.U., F.S.L., J.R.P., R.M.T., E.G., Y.W.F., R.T.L.); Department of Molecular Genetics, College of Medicine, University of Cincinnati, OH (R.G.W., T.B.T.); and Howard Hughes Medical Institute, Section on Developmental and Stem Cell Biology, Joslin Diabetes Center, Boston, MA (M.C., J.G., A.J.W.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.115.307521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748736PMC
January 2016

Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells.

Genome Res 2015 Dec 1;25(12):1860-72. Epub 2015 Oct 1.

Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02140, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02140, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.192237.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4665007PMC
December 2015

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts.

Stem Cells Transl Med 2015 Oct 7;4(10):1101-8. Epub 2015 Aug 7.

Sections of Islet Cell and Regenerative Biology and Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5966/sctm.2014-0217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572895PMC
October 2015

Transcriptome analysis identifies regulators of hematopoietic stem and progenitor cells.

Stem Cell Reports 2013 15;1(3):266-80. Epub 2013 Aug 15.

Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA ; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA ; The Shraga Segal Department of Microbiology, Immunology, and Genetics, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2013.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849420PMC
May 2015

High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice.

Stem Cell Res 2015 May 18;14(3):307-22. Epub 2015 Feb 18.

Howard Hughes Medical Institute, USA; Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA; Joslin Diabetes Center, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02215, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18735061150002
Publisher Site
http://dx.doi.org/10.1016/j.scr.2015.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439311PMC
May 2015

Engineering Escherichia coli into a protein delivery system for mammalian cells.

ACS Synth Biol 2015 May 24;4(5):644-54. Epub 2015 Apr 24.

†Department of Medicine, Division of Infectious Diseases, Massachusetts General Hospital, Cambridge, Massachusetts 02139, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acssynbio.5b00002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487226PMC
May 2015

Young, proliferative thymic epithelial cells engraft and function in aging thymuses.

J Immunol 2015 May 13;194(10):4784-95. Epub 2015 Apr 13.

Joslin Diabetes Center, Boston, MA 02215; Harvard Stem Cell Institute, Cambridge, MA 02138;

View Article

Download full-text PDF

Source
http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1403158
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1403158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481326PMC
May 2015

Myogenic tumors in nevoid Basal cell carcinoma syndrome.

J Pediatr Hematol Oncol 2015 Mar;37(2):147-9

*Department of Pediatric Oncology, Dana-Farber Cancer Institute †Division of Pediatric Hematology/Oncology, Boston Children's Hospital ¶Department of Pathology, Boston Children's Hospital ‡Howard Hughes Medical Institute §Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University ∥Joslin Diabetes Center #Department of Pathology, Brigham and Women's Hospital, Boston, MA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPH.0000000000000115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127382PMC
March 2015

Distinct malignant behaviors of mouse myogenic tumors induced by different oncogenetic lesions.

Front Oncol 2015 24;5:50. Epub 2015 Feb 24.

Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University , Boston, MA , USA ; Howard Hughes Medical Institute , Chevy Chase, MD , USA ; Joslin Diabetes Center , Boston, MA , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2015.00050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338657PMC
March 2015

How stem cells get "turned on".

Authors:
Amy J Wagers

EMBO J 2014 Dec 24;33(23):2743-4. Epub 2014 Oct 24.

Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.201490272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282553PMC
December 2014

Testosterone is essential for skeletal muscle growth in aged mice in a heterochronic parabiosis model.

Cell Tissue Res 2014 Sep 24;357(3):815-21. Epub 2014 May 24.

Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00441-014-1900-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149819PMC
September 2014

The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.

Cancer Cell 2014 Aug 31;26(2):273-87. Epub 2014 Jul 31.

Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2014.05.029DOI Listing
August 2014

Stem cell aging: mechanisms, regulators and therapeutic opportunities.

Nat Med 2014 Aug;20(8):870-80

1] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA. [2] Joslin Diabetes Center, Boston, Massachusetts, USA. [3] Howard Hughes Medical Institute, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160113PMC
August 2014

Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.

Cell Rep 2014 Jul 4;8(1):256-71. Epub 2014 Jul 4.

Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096327PMC
July 2014

Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers.

Cancer 2014 Apr 30;120(7):1068-75. Epub 2013 Dec 30.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Division of Pediatric Hematology/ Oncology, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; Howard Hughes Medical Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, Massachusetts; Joslin Diabetes Center, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cncr.28507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173134PMC
April 2014

Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma.

PLoS Genet 2014 Jan 16;10(1):e1004107. Epub 2014 Jan 16.

Pediatric Cancer Biology Program, Papé Family Pediatric Research Institute, Department of Pediatrics, Oregon Health & Science University, Portland, Oregon, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894165PMC
January 2014

Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis.

Cell 2014 Jan;156(3):440-55

Stem Cell Program, Boston Children's Hospital, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00928674140000
Publisher Site
http://dx.doi.org/10.1016/j.cell.2013.12.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951122PMC
January 2014

Isolation of progenitors that exhibit myogenic/osteogenic bipotency in vitro by fluorescence-activated cell sorting from human fetal muscle.

Stem Cell Reports 2014 Jan 14;2(1):92-106. Epub 2014 Jan 14.

Howard Hughes Medical Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, MA 02138, USA ; Joslin Diabetes Center and the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stemcr.2013.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966115PMC
January 2014

New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism.

Cell Metab 2013 Dec 12;18(6):775-91. Epub 2013 Sep 12.

Section of Islet Cell and Regenerative Biology, Joslin Diabetes Center, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2013.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858409PMC
December 2013

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.

Nat Biotechnol 2013 Oct 8;31(10):898-907. Epub 2013 Sep 8.

1] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA. [2] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Department of Cardiology, Children's Hospital Boston, Boston, Massachusetts, USA. [4] Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital Boston, Boston, Massachusetts, USA. [5] Boston and Harvard Stem Cell Institute, Cambridge, Massachusetts, USA. [6].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.2682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058317PMC
October 2013

Mutations in Hedgehog pathway genes in fetal rhabdomyomas.

J Pathol 2013 Sep;231(1):44-52

Howard Hughes Medical Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/path.4229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875333PMC
September 2013

Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.

Cell Stem Cell 2013 Sep 11;13(3):285-99. Epub 2013 Jul 11.

Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, Division of Hematology/Oncology, Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2013.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769504PMC
September 2013

Overlapping roles for endothelial selectins in murine hematopoietic stem/progenitor cell homing to bone marrow.

Exp Hematol 2013 Jul 14;41(7):588-96. Epub 2013 Mar 14.

Department of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exphem.2013.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700604PMC
July 2013

A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development.

Development 2013 Jun 24;140(11):2354-64. Epub 2013 Apr 24.

Stem Cell Program and Division of Hematology/Oncology, Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dev.biologists.org/cgi/doi/10.1242/dev.088427
Publisher Site
http://dx.doi.org/10.1242/dev.088427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653557PMC
June 2013

Induction of histiocytic sarcoma in mouse skeletal muscle.

PLoS One 2012 31;7(8):e44044. Epub 2012 Aug 31.

Howard Hughes Medical Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, and Joslin Diabetes Center, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044044PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432091PMC
February 2013

Skeletal muscle degenerative diseases and strategies for therapeutic muscle repair.

Annu Rev Pathol 2013 Jan 1;8:441-75. Epub 2012 Nov 1.

Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1146/annurev-pathol-011811-132450DOI Listing
January 2013

Short-term calorie restriction enhances skeletal muscle stem cell function.

Cell Stem Cell 2012 May;10(5):515-9

Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, 7 Divinity Avenue, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2012.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561899PMC
May 2012

The stem cell niche in regenerative medicine.

Authors:
Amy J Wagers

Cell Stem Cell 2012 Apr;10(4):362-9

Howard Hughes Medical Institute, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19345909120007
Publisher Site
http://dx.doi.org/10.1016/j.stem.2012.02.018DOI Listing
April 2012

Efficient generation of iPS cells from skeletal muscle stem cells.

PLoS One 2011 18;6(10):e26406. Epub 2011 Oct 18.

Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Boston, Massachusetts, United Stated of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026406PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196574PMC
February 2012

Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.

Nature 2012 Feb 29;483(7388):227-31. Epub 2012 Feb 29.

Department of Dermatology and Harvard Skin Disease Research Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nature10851
Publisher Site
http://dx.doi.org/10.1038/nature10851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437663PMC
February 2012

Rejuvenation of regeneration in the aging central nervous system.

Cell Stem Cell 2012 Jan;10(1):96-103

MRC Centre for Stem Cell Biology and Regenerative Medicine & Cambridge Centre for Brain Repair & Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19345909110058
Publisher Site
http://dx.doi.org/10.1016/j.stem.2011.11.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714794PMC
January 2012

Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells.

Proc Natl Acad Sci U S A 2011 Dec 30;108(50):20002-7. Epub 2011 Nov 30.

The Howard Hughes Medical Institute and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1111733108
Publisher Site
http://dx.doi.org/10.1073/pnas.1111733108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3250188PMC
December 2011

Dynamic niches in the origination and differentiation of haematopoietic stem cells.

Nat Rev Mol Cell Biol 2011 Sep 2;12(10):643-55. Epub 2011 Sep 2.

Department of Stem Cell and Regenerative Biology, Harvard University, Harvard Stem Cell Institute, 7 Divinity Ave., Cambridge, Massachusetts 02138, USA. Leo.Wang@ childrens.harvard.edu

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrm3184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040463PMC
September 2011

Stem cells for skeletal muscle repair.

Philos Trans R Soc Lond B Biol Sci 2011 Aug;366(1575):2297-306

Department of Stem Cell and Regenerative Biology, Howard Hughes Medical Institute, Harvard University and Joslin Diabetes Center, Bauer Center, 7 Divinity Avenue, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1098/rstb.2011.0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130421PMC
August 2011

Use of the parabiotic model in studies of cutaneous wound healing to define the participation of circulating cells.

Wound Repair Regen 2010 Jul-Aug;18(4):426-32. Epub 2010 Jun 8.

Division of Plastic Surgery, Brigham & Women's Hospital, Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1524-475X.2010.00595.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935287PMC
November 2010

Pax3 induces differentiation of juvenile skeletal muscle stem cells without transcriptional upregulation of canonical myogenic regulatory factors.

J Cell Sci 2010 Aug 6;123(Pt 15):2632-9. Epub 2010 Jul 6.

Section on Developmental and Stem Cell Biology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.061606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908050PMC
August 2010

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.

Nat Biotechnol 2010 Aug 19;28(8):848-55. Epub 2010 Jul 19.

Howard Hughes Medical Institute and Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Medical School, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.1667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148605PMC
August 2010

Immuno-analysis and FACS sorting of adult muscle fiber-associated stem/precursor cells.

Methods Mol Biol 2010 ;621:165-73

Department of BioEngineering, University of California, Berkeley, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60761-063-2_11DOI Listing
July 2010

Muscling in: Uncovering the origins of rhabdomyosarcoma.

Nat Med 2010 Feb;16(2):171-3

Department of Stem Cell and Regenerative Biology, Howard Hughes Medical Institute, Harvard University and Joslin Diabetes Center, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm0210-171DOI Listing
February 2010

Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells.

PLoS One 2010 Jan 20;5(1):e8785. Epub 2010 Jan 20.

Institute for Biology of Stem Cells, Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008785PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808351PMC
January 2010

Systemic signals regulate ageing and rejuvenation of blood stem cell niches.

Nature 2010 Jan;463(7280):495-500

Department of Stem Cell and Regenerative Biology, Harvard University, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Joslin Diabetes Center, One Joslin Place, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature08749DOI Listing
January 2010

Improved cutaneous healing in diabetic mice exposed to healthy peripheral circulation.

J Invest Dermatol 2009 Sep 19;129(9):2265-74. Epub 2009 Mar 19.

Department of Stem Cell and Regenerative Biology, Joslin Diabetes Center, Harvard University, Boston, Massachusetts 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2009.60DOI Listing
September 2009

Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells.

Mol Biol Cell 2009 Jul 20;20(14):3170-7. Epub 2009 May 20.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.e08-12-1185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710837PMC
July 2009

Osteolineage niche cells initiate hematopoietic stem cell mobilization.

Blood 2008 Aug 2;112(3):519-31. Epub 2008 May 2.

Section on Developmental and Stem Cell Biology, Joslin Diabetes Center, Department of Stem Cell and Regenerative Biology, Harvard University, and Harvard Stem Cell Institute, Boston, MA 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2008-01-133710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481533PMC
August 2008

Highly efficient, functional engraftment of skeletal muscle stem cells in dystrophic muscles.

Cell 2008 Jul;134(1):37-47

Section on Developmental and Stem Cell Biology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2008.05.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665268PMC
July 2008

Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells.

Proc Natl Acad Sci U S A 2008 Jul 23;105(30):10420-5. Epub 2008 Jul 23.

Divisions of Endocrinology and Gastroenterology, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0804800105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2492454PMC
July 2008

The transcription factor EGR1 controls both the proliferation and localization of hematopoietic stem cells.

Cell Stem Cell 2008 Apr;2(4):380-91

Section on Developmental and Stem Cell Biology, Joslin Diabetes Center, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2008.01.015DOI Listing
April 2008