Amr H Sawalha

Amr H Sawalha

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Amr H Sawalha

Publications by authors named "Amr H Sawalha"

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Genetics of Antiphospholipid Syndrome.

Curr Rheumatol Rep 2019 Dec 5;21(12):65. Epub 2019 Dec 5.

Division of Rheumatology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh, 7123 Rangos Research Center, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.

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http://dx.doi.org/10.1007/s11926-019-0869-yDOI Listing
December 2019

Inhibition of EZH2 Ameliorates Lupus-Like Disease in MRL/lpr Mice.

Arthritis Rheumatol 2019 Oct 12;71(10):1681-1690. Epub 2019 Aug 12.

University of Michigan, Ann Arbor, and University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/art.40931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764871PMC
October 2019

Takayasu arteritis risk locus in represses the anti-inflammatory gene through chromatin looping and recruiting MEF2-HDAC complex.

Ann Rheum Dis 2019 Oct 17;78(10):1388-1397. Epub 2019 Jul 17.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA

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http://dx.doi.org/10.1136/annrheumdis-2019-215567DOI Listing
October 2019

Elucidating the role of the epigenetic regulator EZH2 in lupus.

Authors:
Amr H Sawalha

Arthritis Rheumatol 2019 Oct 10. Epub 2019 Oct 10.

Division of Rheumatology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1002/art.41132DOI Listing
October 2019

Monogenic Lupus: A Developing Paradigm of Disease.

Front Immunol 2018 30;9:2496. Epub 2018 Oct 30.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fimmu.2018.02496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232876PMC
September 2019

BCL-6 and EZH2 cooperate to epigenetically repress anti-inflammatory miR-142-3p/5p in lupus CD4+T cells.

Authors:
Amr H Sawalha

Cell Mol Immunol 2019 Sep 11. Epub 2019 Sep 11.

Division of Rheumatology, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1038/s41423-019-0288-zDOI Listing
September 2019

Genome-wide DNA methylation analysis in ankylosing spondylitis identifies HLA-B*27 dependent and independent DNA methylation changes in whole blood.

J Autoimmun 2019 Aug 23;102:126-132. Epub 2019 May 23.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Division of Rheumatology, Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA; Division of Rheumatology, Department of Medicine & Lupus Center of Excellence, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2019.04.022DOI Listing
August 2019

Deoxyribonucleic Acid Methylation in Systemic Lupus Erythematosus: Implications for Future Clinical Practice.

Front Immunol 2018 24;9:875. Epub 2018 Apr 24.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fimmu.2018.00875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928134PMC
July 2019

Hypomethylation of and is associated with type-I interferon-dependent expression in lupus CD8+ T cells.

Ann Rheum Dis 2019 Apr 23;78(4):519-528. Epub 2019 Jan 23.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA

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http://dx.doi.org/10.1136/annrheumdis-2018-214323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679955PMC
April 2019

Inhibition of EZH2 prevents fibrosis and restores normal angiogenesis in scleroderma.

Proc Natl Acad Sci U S A 2019 02 12;116(9):3695-3702. Epub 2019 Feb 12.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109;

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http://dx.doi.org/10.1073/pnas.1813006116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397533PMC
February 2019

Clinical immunology: A special issue on epigenetics.

Authors:
Amr H Sawalha

Clin Immunol 2018 11 22;196:1-2. Epub 2018 Nov 22.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216616183067
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http://dx.doi.org/10.1016/j.clim.2018.11.012DOI Listing
November 2018

Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils.

Clin Immunol 2018 11 22;196:110-116. Epub 2018 Nov 22.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413498PMC
November 2018

Drug-induced lupus erythematosus: an update on drugs and mechanisms.

Authors:
Ye He Amr H Sawalha

Curr Opin Rheumatol 2018 09;30(5):490-497

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000522DOI Listing
September 2018

Methyl-CpG-binding protein 2 mediates antifibrotic effects in scleroderma fibroblasts.

Ann Rheum Dis 2018 08 14;77(8):1208-1218. Epub 2018 May 14.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1136/annrheumdis-2018-213022DOI Listing
August 2018

Caffeine inhibits STAT1 signaling and downregulates inflammatory pathways involved in autoimmunity.

Clin Immunol 2018 07 18;192:68-77. Epub 2018 Apr 18.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.04.008DOI Listing
July 2018

Management of Behçet's disease.

Curr Opin Rheumatol 2018 05;30(3):238-242

Division of Rheumatology, School of Medicine, Marmara University, Istanbul, Turkey.

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http://dx.doi.org/10.1097/BOR.0000000000000497DOI Listing
May 2018

Editorial: The Innate and Adaptive Immune Response Are Both Involved in Drug-Induced Autoimmunity.

Authors:
Amr H Sawalha

Arthritis Rheumatol 2018 03 30;70(3):330-333. Epub 2018 Jan 30.

University of Michigan, Ann Arbor.

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http://doi.wiley.com/10.1002/art.40371
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http://dx.doi.org/10.1002/art.40371DOI Listing
March 2018

Novel Transcriptional Activity and Extensive Allelic Imbalance in the Human MHC Region.

J Immunol 2018 02 8;200(4):1496-1503. Epub 2018 Jan 8.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109;

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http://dx.doi.org/10.4049/jimmunol.1701061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823012PMC
February 2018

An update on the role of epigenetics in systemic vasculitis.

Curr Opin Rheumatol 2018 Jan;30(1):4-15

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805392PMC
January 2018

CD4+CD28+KIR+CD11a T cells correlate with disease activity and are characterized by a pro-inflammatory epigenetic and transcriptional profile in lupus patients.

J Autoimmun 2018 01 20;86:19-28. Epub 2017 Oct 20.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821123PMC
January 2018

Sex chromosome contributions to sex differences in multiple sclerosis susceptibility and progression.

Mult Scler 2018 01;24(1):22-31

Multiple Sclerosis Program, Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1177/1352458517737394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823689PMC
January 2018

Behçet's disease in the United States: A single center descriptive and comparative study.

Eur J Rheumatol 2017 Dec 3;4(4):239-244. Epub 2017 Nov 3.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.5152/eurjrheum.2017.17112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741334PMC
December 2017

Unfolding the pathogenesis of scleroderma through genomics and epigenomics.

J Autoimmun 2017 Sep 16;83:73-94. Epub 2017 May 16.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573604PMC
September 2017

The genetics of Takayasu arteritis.

Presse Med 2017 Jul - Aug;46(7-8 Pt 2):e179-e187. Epub 2017 Jul 26.

University of Michigan, department of internal medicine, division of rheumatology, Ann Arbor, MI, USA; University of Michigan, center for computational medicine and bioinformatics, Ann Arbor, MI, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07554982173032
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http://dx.doi.org/10.1016/j.lpm.2016.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753771PMC
September 2017

Clinical Images: Black Esophagus in Antiphospholipid Syndrome.

Arthritis Rheumatol 2017 07 23;69(7):1460. Epub 2017 May 23.

University of Michigan, Ann Arbor, MI.

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http://doi.wiley.com/10.1002/art.40092
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http://dx.doi.org/10.1002/art.40092DOI Listing
July 2017

Epigenetic Variability in Systemic Lupus Erythematosus: What We Learned from Genome-Wide DNA Methylation Studies.

Curr Rheumatol Rep 2017 Jun;19(6):32

Division of Rheumatology, University of Michigan, 5520 MSRB-1, SPC 5680, 1150 W. Medical Center Drive, Ann Arbor, MI, 48109, USA.

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http://dx.doi.org/10.1007/s11926-017-0657-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819620PMC
June 2017

Age-associated DNA methylation changes in naive CD4 T cells suggest an evolving autoimmune epigenotype in aging T cells.

Epigenomics 2017 04 21;9(4):429-445. Epub 2017 Mar 21.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.2217/epi-2016-0143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549647PMC
April 2017

Interview with Amr H Sawalha: epigenetics and autoimmunity.

Authors:
Amr H Sawalha

Epigenomics 2017 04 21;9(4):379-382. Epub 2017 Mar 21.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.2217/epi-2017-0005DOI Listing
April 2017

Analysis of the common genetic component of large-vessel vasculitides through a meta-Immunochip strategy.

Sci Rep 2017 03 9;7:43953. Epub 2017 Mar 9.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1038/srep43953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344032PMC
March 2017

The human microbiome in rheumatic autoimmune diseases: A comprehensive review.

Clin Immunol 2016 Sep 2;170:70-9. Epub 2016 Aug 2.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.07.026DOI Listing
September 2016

Sequencing of 16S rRNA reveals a distinct salivary microbiome signature in Behçet's disease.

Clin Immunol 2016 08 7;169:28-35. Epub 2016 Jun 7.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.06.002DOI Listing
August 2016

Analysis of Systemic Sclerosis-associated Genes in a Turkish Population.

J Rheumatol 2016 07 1;43(7):1376-9. Epub 2016 May 1.

From the Instituto de Parasitología y Biomedicina "López-Neyra," IPBLN-CSIC, PTS Granada, Granada, Spain; Department of Rheumatology, University of Gaziantep, Gaziantep; Division of Rheumatology, Marmara University, School of Medicine; Department of Rheumatology, Istanbul Bilim University, Istanbul, Turkey; Division of Rheumatology, Department of Internal Medicine, University of Michigan; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.F.D. Carmona, PhD, Instituto de Parasitología y Biomedicina "López-Neyra," IPBLN-CSIC, PTS Granada; A.M. Onat, MD, Department of Rheumatology, University of Gaziantep; T. Fernández-Aranguren, BSc, Instituto de Parasitología y Biomedicina "López-Neyra," IPBLN-CSIC, PTS Granada; A. Serrano-Fernández, BSc, Instituto de Parasitología y Biomedicina "López-Neyra," IPBLN-CSIC, PTS Granada; G. Robledo, BSc, Instituto de Parasitología y Biomedicina "López-Neyra," IPBLN-CSIC, PTS Granada; H. Direskeneli, MD, Division of Rheumatology, Marmara University, School of Medicine; A.H. Sawalha, MD, Division of Rheumatology, Department of Internal Medicine, University of Michigan, and the Center for Computational Medicine and Bioinformatics, University of Michigan; S. Yavuz, MD, Department of Rheumatology, Istanbul Bilim University; J. Martín, MD, PhD, Instituto de Parasitología y Biomedicina "López-Neyra," IPBLN-CSIC, PTS Granada.

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http://dx.doi.org/10.3899/jrheum.160045DOI Listing
July 2016

DNA methylation analysis of the temporal artery microenvironment in giant cell arteritis.

Ann Rheum Dis 2016 06 2;75(6):1196-202. Epub 2015 Jun 2.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1136/annrheumdis-2014-207116DOI Listing
June 2016

Epigenetics and Vasculitis: a Comprehensive Review.

Clin Rev Allergy Immunol 2016 Jun;50(3):357-66

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1007/s12016-015-8495-6DOI Listing
June 2016

Histone H2AX phosphorylation as a measure of DNA double-strand breaks and a marker of environmental stress and disease activity in lupus.

Lupus Sci Med 2016 29;3(1):e000148. Epub 2016 Apr 29.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1136/lupus-2016-000148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854117PMC
May 2016

Epigenomic functional characterization of genetic susceptibility variants in systemic vasculitis.

J Autoimmun 2016 Feb 20;67:76-81. Epub 2015 Oct 20.

Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1016/j.jaut.2015.10.002DOI Listing
February 2016

Ethnicity-specific epigenetic variation in naïve CD4+ T cells and the susceptibility to autoimmunity.

Epigenetics Chromatin 2015 24;8:49. Epub 2015 Nov 24.

Division of Rheumatology, University of Michigan, 5520 MSRB-1, SPC 5680, 1150 W. Medical Center Drive, Ann Arbor, MI 48109 USA ; Center for Computational Medicine and Bioinformatics, University of Michigan, 100 Washtenaw Ave, #2017, Ann Arbor, MI 48109 USA.

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http://dx.doi.org/10.1186/s13072-015-0037-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659164PMC
November 2015

Magnetic Resonance Imaging and Computed Tomography in the Evaluation of Crowned Dens Syndrome Secondary to Calcium Pyrophosphate Dihydrate.

J Clin Rheumatol 2015 Oct;21(7):368-9

From the *Division of Rheumatology, Department of Internal Medicine, †Department of Radiology, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1097/RHU.0000000000000315DOI Listing
October 2015

Systemic lupus erythematosus complicated by diffuse alveolar haemorrhage: risk factors, therapy and survival.

Lupus Sci Med 2015 23;2(1):e000117. Epub 2015 Sep 23.

Division of Rheumatology, Department of Internal Medicine , University of Michigan , Ann Arbor, Michigan , USA.

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http://dx.doi.org/10.1136/lupus-2015-000117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586940PMC
October 2015

DNA methylation patterns in naïve CD4+ T cells identify epigenetic susceptibility loci for malar rash and discoid rash in systemic lupus erythematosus.

Lupus Sci Med 2015 15;2(1):e000101. Epub 2015 Sep 15.

Division of Rheumatology, Department of Internal Medicine , University of Michigan , Ann Arbor, Michigan , USA ; Center for Computational Medicine and Bioinformatics, University of Michigan , Ann Arbor, Michigan , USA.

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http://dx.doi.org/10.1136/lupus-2015-000101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577980PMC
September 2015

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies.

Ann Rheum Dis 2015 Aug 8;74(8):1612-20. Epub 2014 May 8.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1136/annrheumdis-2014-205303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224992PMC
August 2015

Renal involvement in lupus is characterized by unique DNA methylation changes in naïve CD4+ T cells.

J Autoimmun 2015 Jul 23;61:29-35. Epub 2015 May 23.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497927PMC
July 2015

T cell PKCδ kinase inactivation induces lupus-like autoimmunity in mice.

Clin Immunol 2015 Jun 28;158(2):193-203. Epub 2015 Mar 28.

Department of Medicine, University of Michigan, Ann Arbor, MI, USA; Ann Arbor VA Medical Center, Ann Arbor, MI, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15216616150011
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http://dx.doi.org/10.1016/j.clim.2015.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464903PMC
June 2015

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils.

J Autoimmun 2015 Apr 28;58:59-66. Epub 2015 Jan 28.

Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2015.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363276PMC
April 2015

The DNA methylation signature of human TCRαβ+CD4-CD8- double negative T cells reveals CG demethylation and a unique epigenetic architecture permissive to a broad stimulatory immune response.

Clin Immunol 2015 Jan 29;156(1):19-27. Epub 2014 Oct 29.

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216616140024
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http://dx.doi.org/10.1016/j.clim.2014.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278938PMC
January 2015

Autoimmune disease in the epigenetic era: how has epigenetics changed our understanding of disease and how can we expect the field to evolve?

Expert Rev Clin Immunol 2015 Jan;11(1):45-58

Department of Internal Medicine, Division of Rheumatology, Immunology and Allergy, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1586/1744666X.2015.994507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636192PMC
January 2015

Hydroxychloroquine-induced hyperpigmentation of the skin.

Authors:
Amr H Sawalha

J Rheumatol 2015 Jan;42(1):135-6

Division of Rheumatology, Department of Internal Medicine, and Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.3899/jrheum.140995DOI Listing
January 2015

DNA methylation and mRNA and microRNA expression of SLE CD4+ T cells correlate with disease phenotype.

J Autoimmun 2014 Nov 3;54:127-36. Epub 2014 Aug 3.

Department of Dermatology, The Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2014.07.002DOI Listing
November 2014

Epigenetics in the treatment of systemic lupus erythematosus: potential clinical application.

Clin Immunol 2014 Nov 16;155(1):79-90. Epub 2014 Sep 16.

Department of Dermatology and Epigenetic Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2014.09.002DOI Listing
November 2014

Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.

Arthritis Rheumatol 2014 Oct;66(10):2804-15

University of Oklahoma Health Sciences Center and Oklahoma Medical Research Foundation, Oklahoma City.

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http://dx.doi.org/10.1002/art.38762DOI Listing
October 2014

GFP affects human T cell activation and cytokine production following in vitro stimulation.

PLoS One 2013 5;8(4):e50068. Epub 2013 Apr 5.

Oklahoma Medical Research Foundation, Arthritis and Clinical Immunology Program, Oklahoma City, Oklahoma, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050068PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618152PMC
October 2013

Epigenetics in the pathogenesis of systemic lupus erythematosus.

Curr Opin Rheumatol 2013 Sep;25(5):569-76

Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1097/BOR.0b013e328364206fDOI Listing
September 2013

Impaired DNA methylation and its mechanisms in CD4(+)T cells of systemic lupus erythematosus.

J Autoimmun 2013 Mar 20;41:92-9. Epub 2013 Jan 20.

Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenetics, Changsha, Hunan 410011, PR China.

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https://linkinghub.elsevier.com/retrieve/pii/S08968411130000
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http://dx.doi.org/10.1016/j.jaut.2013.01.005DOI Listing
March 2013

Murine models of lupus induced by hypomethylated T cells (DNA hypomethylation and lupus…).

Methods Mol Biol 2012 ;900:169-80

University of Michigan and the Ann Arbor Veteran's Affairs Hospital, Ann Arbor, MI, USA.

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January 2013

The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus.

Arthritis Res Ther 2011 31;13(5):245. Epub 2011 Oct 31.

Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308098PMC
December 2012

Epigenetics in systemic lupus erythematosus: leading the way for specific therapeutic agents.

Int J Clin Rheumtol 2011 Aug;6(4):423-439

Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

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http://dx.doi.org/10.2217/ijr.11.32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241218PMC
August 2011

An update on belimumab for the treatment of lupus.

Biologics 2011 14;5:33-43. Epub 2011 Feb 14.

Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA;

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http://dx.doi.org/10.2147/BTT.S13804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044792PMC
July 2011

Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus.

Epigenetics 2011 May 1;6(5):593-601. Epub 2011 May 1.

Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

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http://dx.doi.org/10.4161/epi.6.5.15374DOI Listing
May 2011