Amos J Simon

Amos J Simon

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Amos J Simon

Amos J Simon

Publications by authors named "Amos J Simon"

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63Publications

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Cardiac leptin overexpression in the context of acute MI and reperfusion potentiates myocardial remodeling and left ventricular dysfunction.

PLoS One 2018 12;13(10):e0203902. Epub 2018 Oct 12.

Department of Vascular Surgery, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Isreal.

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October 2018

Novel Mutations in RASGRP1 are Associated with Immunodeficiency, Immune Dysregulation, and EBV-Induced Lymphoma.

J Clin Immunol 2018 Aug 20;38(6):699-710. Epub 2018 Jul 20.

Pediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center; Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 52621, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2018

MHC II deficient infant identified by newborn screening program for SCID.

Immunol Res 2018 Aug;66(4):537-542

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2018

Correction to: Novel Mutations in RASGRP1 Are Associated with Immunodeficiency, Immune Dysregulation, and EBV-Induced Lymphoma.

J Clin Immunol 2018 Aug;38(6):711

Pediatric Department A and the Immunology Service, JeffreyModell Foundation Center; Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, 52621, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2018

Co-appearance of OPV and BCG vaccine-derived complications in two infants with severe combined immunodeficiency.

Immunol Res 2018 Jun;66(3):437-443

Pediatric Department A and the Immunology Services, "Edmond and Lily Safra" Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer affiliated with the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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June 2018

First Year of Israeli Newborn Screening for Severe Combined Immunodeficiency-Clinical Achievements and Insights.

Front Immunol 2017 6;8:1448. Epub 2017 Nov 6.

Pediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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November 2017

Zinc enhances temozolomide cytotoxicity in glioblastoma multiforme model systems.

Oncotarget 2016 Nov;7(46):74860-74871

Pediatric Hemato-Oncology, Edmond and Lilly Safra Children's Hospital and Cancer Research Center, Sheba Medical Center, Tel Hashomer Affiliated to The Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.

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November 2016

A Novel Mutation in a Critical Region for the Methyl Donor Binding in DNMT3B Causes Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome (ICF).

J Clin Immunol 2016 11 12;36(8):801-809. Epub 2016 Oct 12.

Pediatric Department A and the Immunology Service, Jeffrey Modell Foundation Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel-Hashomer, Ramat Gan, Israel.

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November 2016

Combined immunodeficiency in a patient with mosaic monosomy 21.

Immunol Res 2016 08;64(4):841-7

Pediatric Department A and the Immunology Service, "Edmond and Lily Safra" Children's Hospital, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2016

Mutations in STN1 cause Coats plus syndrome and are associated with genomic and telomere defects.

J Exp Med 2016 07 18;213(8):1429-40. Epub 2016 Jul 18.

Pediatric Department A and Immunology Service, Jeffrey Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel The Wohl Institute for Translational Medicine, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel

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July 2016

Highlighting the problematic reliance on CD18 for diagnosing leukocyte adhesion deficiency type 1.

Immunol Res 2016 Apr;64(2):476-82

Pediatric Department and the Immunology Service, "Edmond and Lily Safra" Children's Hospital, Chaim Sheba Medical Center, 52621, Tel Hashomer, Israel.

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April 2016

High metallothionein predicts poor survival in glioblastoma multiforme.

BMC Med Genomics 2015 Oct 22;8:68. Epub 2015 Oct 22.

Pediatric Hemato-Oncology, Edmond and Lilly Safra Children's Hospital and Cancer Research Center, Sheba Medical Center, Tel Hashomer affiliated to the Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.

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October 2015

Correlation between 'ACKR1/DARC null' polymorphism and benign neutropenia in Yemenite Jews.

Br J Haematol 2015 Sep 26;170(6):892-5. Epub 2015 Mar 26.

Cancer Research Centre, Sheba Medical Centre, Tel Hashomer, Israel.

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September 2015

Thymic and bone marrow output in individuals with 22q11.2 deletion syndrome.

Pediatr Res 2015 Apr 12;77(4):579-85. Epub 2015 Jan 12.

1] Pediatric Department B and Immunology Services, Jeffrey Modell Foundation Center, Sheba Medical Center, Tel Hashomer, Israel [2] Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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April 2015

Insight into normal thymic activity by assessment of peripheral blood samples.

Immunol Res 2015 Mar;61(3):198-205

Pediatric Department B, Pediatric Immunology Service, Jeffrey Modell Foundation (JMF) Center, Edmond and Lily Safra Children's Hospital, Chaim Sheba Medical Center, 52621, Tel Hashomer, Israel.

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March 2015

Timely and spatially regulated maturation of B and T cell repertoire during human fetal development.

Sci Transl Med 2015 Feb;7(276):276ra25

Pediatric Immunology Unit, Jeffrey Modell Foundation Center, and Department of Pediatrics, the Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 5262100, Israel.

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February 2015

Testicular failure in a patient with G6PC3 deficiency.

Pediatr Res 2014 Aug 5;76(2):197-201. Epub 2014 May 5.

1] Pediatric Department, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel [2] Cancer Research Center, Pediatric Immunology Service, Jeffrey Modell Foundation (JMF) Center, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2014

Disturbed B and T cell homeostasis and neogenesis in patients with ataxia telangiectasia.

J Clin Immunol 2014 Jul 1;34(5):561-72. Epub 2014 May 1.

Pediatric Immunology Unit, Jeffrey Modell Foundation (JMF) Center and Department of Pediatrics, Sheba Medical Center, Tel Hashomer, Israel.

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July 2014

Novel SMARCAL1 bi-allelic mutations associated with a chromosomal breakage phenotype in a severe SIOD patient.

J Clin Immunol 2014 Jan 7;34(1):76-83. Epub 2013 Nov 7.

Cancer Research Center, Chaim Sheba Medical Center, Tel Hashomer, 52621, Israel,

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January 2014

Characterizing T cells in SCID patients presenting with reactive or residual T lymphocytes.

Clin Dev Immunol 2012 20;2012:261470. Epub 2012 Nov 20.

Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, 69978 Tel Aviv, Israel.

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August 2013

Newborn screening for severe T and B cell immunodeficiency in Israel: a pilot study.

Isr Med Assoc J 2013 Aug;15(8):404-9

Cancer Research Center, Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.

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August 2013

Purine nucleoside phosphorylase deficiency presenting as severe combined immune deficiency.

Immunol Res 2013 May;56(1):150-4

Cancer Research Center, Pediatric Department, Pediatric Immunology Service, Jeffery Modell Foundation (JMF) Center, Edmond and Lily Safra Children's Hospital, Tel Aviv University, Tel Aviv, Israel.

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May 2013

Thymic function in MHC class II-deficient patients.

J Allergy Clin Immunol 2013 Mar 8;131(3):831-9. Epub 2012 Dec 8.

Cancer Research Center, Jeffery Modell Foundation Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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March 2013

Leptin locally synthesized in carotid atherosclerotic plaques could be associated with lesion instability and cerebral emboli.

J Am Heart Assoc 2012 Oct 25;1(5):e001727. Epub 2012 Oct 25.

Department of Vascular Surgery and the Gottesdiener Vascular Biology Laboratory, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.

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October 2012

Thymic functions and gene expression profile distinct double-negative cells from single positive cells in the autoimmune lymphoproliferative syndrome.

Autoimmun Rev 2012 Aug 18;11(10):723-30. Epub 2012 Jan 18.

Cancer Research Center, Sheba Medical Center, Tel Hashomer affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2012

T- and B-cell defects in a novel purine nucleoside phosphorylase mutation.

J Allergy Clin Immunol 2012 Aug 10;130(2):539-42. Epub 2012 May 10.

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August 2012

C1824T mutation in the LMNA gene has no association with senile cataract.

Neurobiol Aging 2012 Jul 10;33(7):1487.e15-9. Epub 2011 Nov 10.

The Krieger Eye Research Laboratory, Felsenstein Medical Research Center, Petah Tiqwa, Tel Aviv, Israel.

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July 2012

Increased RNA editing in children with cyanotic congenital heart disease.

Intensive Care Med 2011 Oct 1;37(10):1664-71. Epub 2011 Jul 1.

Department of Pediatric Critical Care Medicine, Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.

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October 2011

MeCP2 deficiency downregulates specific nuclear proteins that could be partially recovered by valproic acid in vitro.

Epigenetics 2010 Jan 13;5(1):61-7. Epub 2010 Jan 13.

Sagol Neuroscience Center, Sheba Medical Center, Tel Hashomer, Israel.

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January 2010

Reduced central tolerance in Omenn syndrome leads to immature self-reactive oligoclonal T cells.

J Allergy Clin Immunol 2009 Oct 19;124(4):793-800. Epub 2009 Sep 19.

Cancer Research Center, Safra Children's Hospital, Sheba Medical Center, Tel Hashomer and Sackler School of Medicine, Tel Aviv, Israel.

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October 2009

Elevated CO2 levels affect development, motility, and fertility and extend life span in Caenorhabditis elegans.

Proc Natl Acad Sci U S A 2009 Mar 23;106(10):4024-9. Epub 2009 Feb 23.

Department of Genetics, Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem 91904, Israel.

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March 2009

Leptin receptor is elevated in carotid plaques from neurologically symptomatic patients and positively correlated with augmented macrophage density.

J Vasc Surg 2008 Nov 30;48(5):1146-55. Epub 2008 Sep 30.

Department of Vascular Surgery and the Gottesdiener Vascular Biology Laboratory, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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November 2008

Synovial VLA-1+ T cells display an oligoclonal and partly distinct repertoire in rheumatoid and psoriatic arthritis.

Clin Immunol 2008 Jul 5;128(1):75-84. Epub 2008 May 5.

Cancer Research Center and Institute of Hematology, The Chaim Sheba Medical Center, Tel Aviv University, Israel.

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July 2008

The human granulocyte nucleus: Unusual nuclear envelope and heterochromatin composition.

Eur J Cell Biol 2008 May 8;87(5):279-90. Epub 2008 Apr 8.

Department of Biology, Bowdoin College, Brunswick, ME 04011, USA.

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May 2008

LAP2zeta binds BAF and suppresses LAP2beta-mediated transcriptional repression.

Eur J Cell Biol 2008 May 9;87(5):267-78. Epub 2008 Apr 9.

Sheba Cancer Research Center and the Institute of Hematology, Chaim Sheba Medical Center, Tel-Hashomer, 52621, Israel.

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May 2008

Mechanisms operative in the antitumor activity of temozolomide in glioblastoma multiforme.

Cancer J 2007 Sep-Oct;13(5):335-44

Department of Pediatric Hemato-Oncology, Safra Children's Hospital and the Institute of Hematology, Tel-Hashomer, Israel.

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January 2008

Enhanced expression of the nuclear envelope LAP2 transcriptional repressors in normal and malignant activated lymphocytes.

Ann Hematol 2007 Jun 16;86(6):393-401. Epub 2007 Mar 16.

Sheba Cancer Research Center, Institute of Hematology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

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June 2007

Nuclear lamina organization and new functions. The wall and yard guardians of gene expression.

Authors:
Amos J Simon

FEBS J 2007 Mar;274(6):1353

Sheba Cancer Research Center and the Institute of Hematology, The Chaim Sheba Medical Center, Tel Hashomer and the Sackler School of Medicine, Tel Aviv University, Israel.

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March 2007

Gene silencing at the nuclear periphery.

FEBS J 2007 Mar;274(6):1383-92

Sheba Cancer Research Center and the Institute of Hematology, The Chaim Sheba Medical Center, Tel Hashomer and the Sackler School of Medicine, Tel Aviv University, Israel.

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March 2007

BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphoma.

Blood 2006 Feb 25;107(4):1599-607. Epub 2005 Oct 25.

Pediatric Hematology-Oncology, Safra Children's Hospital, Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel.

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February 2006

The nuclear-envelope protein and transcriptional repressor LAP2beta interacts with HDAC3 at the nuclear periphery, and induces histone H4 deacetylation.

J Cell Sci 2005 Sep;118(Pt 17):4017-25

Sheba Cancer Research Center and Institute of Hematology, The Chaim Sheba Medical Center, Tel-Hashomer 52621, Israel.

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September 2005

Nuclear envelopathies--raising the nuclear veil.

Pediatr Res 2005 May 6;57(5 Pt 2):8R-15R. Epub 2005 Apr 6.

Sheba Cancer Research Center, Institute of Hematology, The Chaim Sheba Medical Center and Sackler School of Medicine, Tel-Aviv University, Israel.

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May 2005

Angiogenic factors in the cerebrospinal fluid of patients with astrocytic brain tumors.

Neurosurgery 2004 Sep;55(3):562-7; discussion 567-8

Department of Neurosurgery, Sheba Medical Center, Tel-Hashomer and Tel Aviv University, Sackler School of Medicine, Tel Aviv, Israel.

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September 2004

Histone deacetylase inhibitors--a new tool to treat cancer.

Cancer Treat Rev 2004 Aug;30(5):461-72

Laboratory of Molecular Hemato-Oncology, Sheba Cancer Research Center, Chaim Sheba Medical Center, Tel-Hashomer, Sackler School of Medicine, Tel-Aviv University, Israel.

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August 2004

Effect of CD3delta deficiency on maturation of alpha/beta and gamma/delta T-cell lineages in severe combined immunodeficiency.

N Engl J Med 2003 Nov;349(19):1821-8

Divisions of Immunology and Allergy and the Infection, Immunity, Injury and Repair Program, the Research Institute and the Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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November 2003