Publications by authors named "Amit U Joshi"

16Publications

Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy.

J Neuroinflammation 2020 Jan 27;17(1):36. Epub 2020 Jan 27.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

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January 2020

Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer's disease related pathology.

Acta Neuropathol Commun 2019 12 12;7(1):190. Epub 2019 Dec 12.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

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December 2019

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.

Nat Neurosci 2019 10 23;22(10):1635-1648. Epub 2019 Sep 23.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

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October 2019

Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes.

Circ Res 2019 06 20;125(1):90-103. Epub 2019 May 20.

From the Stanford Cardiovascular Institute (A.E., Y.D., S.S., H.C., Y.L., P.G., J.C.W.), Stanford University School of Medicine, CA.

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June 2019

Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy.

J Mol Cell Cardiol 2019 05 11;130:160-169. Epub 2019 Apr 11.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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May 2019

Mortal engines: Mitochondrial bioenergetics and dysfunction in neurodegenerative diseases.

Pharmacol Res 2018 12 23;138:2-15. Epub 2018 Aug 23.

Department of Chemical and Systems Biology, School of Medicine, Stanford University, CA, 94305-5174, USA. Electronic address:

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December 2018

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease.

Oncotarget 2018 Jan 22;9(5):6128-6143. Epub 2017 Dec 22.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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January 2018

Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis.

EMBO Mol Med 2018 03;10(3)

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA

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March 2018

The Role of Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) in Neuropathology and Neurodegeneration.

Acta Neurol Taiwan 2016 Dec;25(4):111-123

Department of Chemical and Systems Biology, Stanford University, School of Medicine, Stanford CA 94305-5174 USA.

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December 2016

Potential biomarkers to follow the progression and treatment response of Huntington's disease.

J Exp Med 2016 11 7;213(12):2655-2669. Epub 2016 Nov 7.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305

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November 2016

The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.

Cell Calcium 2016 09 7;60(3):218-34. Epub 2016 May 7.

Department of Chemical & Systems Biology, School of Medicine, Stanford University, CA, USA. Electronic address:

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September 2016

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death.

J Biol Chem 2016 Jun 27;291(26):13608-21. Epub 2016 Apr 27.

From the Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305-5174 and

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June 2016