Publications by authors named "Amit U Joshi"

16Publications

Restoring metabolism of myeloid cells reverses cognitive decline in ageing.

Authors:
Paras S Minhas Amira Latif-Hernandez Melanie R McReynolds Aarooran S Durairaj Qian Wang Amanda Rubin Amit U Joshi Joy Q He Esha Gauba Ling Liu Congcong Wang Miles Linde Yuki Sugiura Peter K Moon Ravi Majeti Makoto Suematsu Daria Mochly-Rosen Irving L Weissman Frank M Longo Joshua D Rabinowitz Katrin I Andreasson

Nature 2021 Jan 20. Epub 2021 Jan 20.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA.

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January 2021

Author Correction: Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.

Authors:
Amit U Joshi Paras S Minhas Shane A Liddelow Bereketeab Haileselassie Katrin I Andreasson Gerald W Dorn Daria Mochly-Rosen

Nat Neurosci 2020 Dec 15. Epub 2020 Dec 15.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

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December 2020

Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes' toxicity.

Authors:
Che-Hong Chen Julio C B Ferreira Amit U Joshi Matthew C Stevens Sin-Jin Li Jade H-M Hsu Rory Maclean Nikolas D Ferreira Pilar R Cervantes Diana D Martinez Fernando L Barrientos Gibran H R Quintanares Daria Mochly-Rosen

EBioMedicine 2020 May 8;55:102753. Epub 2020 May 8.

Department of Chemical and Systems Biology, School of Medicine, Stanford University, CA, USA. Electronic address:

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May 2020

Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy.

Authors:
Bereketeab Haileselassie Amit U Joshi Paras S Minhas Riddhita Mukherjee Katrin I Andreasson Daria Mochly-Rosen

J Neuroinflammation 2020 Jan 27;17(1):36. Epub 2020 Jan 27.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

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January 2020

Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer's disease related pathology.

Authors:
Amit U Joshi Lauren D Van Wassenhove Kelsey R Logas Paras S Minhas Katrin I Andreasson Kenneth I Weinberg Che-Hong Chen Daria Mochly-Rosen

Acta Neuropathol Commun 2019 12 12;7(1):190. Epub 2019 Dec 12.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

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December 2019

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration.

Authors:
Amit U Joshi Paras S Minhas Shane A Liddelow Bereketeab Haileselassie Katrin I Andreasson Gerald W Dorn Daria Mochly-Rosen

Nat Neurosci 2019 10 23;22(10):1635-1648. Epub 2019 Sep 23.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA.

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October 2019

Proteasome-Dependent Regulation of Distinct Metabolic States During Long-Term Culture of Human iPSC-Derived Cardiomyocytes.

Authors:
Antje Ebert Amit U Joshi Sandra Andorf Yuanyuan Dai Shrivatsan Sampathkumar Haodong Chen Yingxin Li Priyanka Garg Karl Toischer Gerd Hasenfuss Daria Mochly-Rosen Joseph C Wu

Circ Res 2019 06 20;125(1):90-103. Epub 2019 May 20.

From the Stanford Cardiovascular Institute (A.E., Y.D., S.S., H.C., Y.L., P.G., J.C.W.), Stanford University School of Medicine, CA.

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June 2019

Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy.

Authors:
Bereketeab Haileselassie Riddhita Mukherjee Amit U Joshi Brooke A Napier Liliana M Massis Nicolai Patrick Ostberg Bruno B Queliconi Denise Monack Daniel Bernstein Daria Mochly-Rosen

J Mol Cell Cardiol 2019 05 11;130:160-169. Epub 2019 Apr 11.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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May 2019

Macrophage de novo NAD synthesis specifies immune function in aging and inflammation.

Authors:
Paras S Minhas Ling Liu Peter K Moon Amit U Joshi Christopher Dove Siddhita Mhatre Kevin Contrepois Qian Wang Brittany A Lee Michael Coronado Daniel Bernstein Michael P Snyder Marie Migaud Ravindra Majeti Daria Mochly-Rosen Joshua D Rabinowitz Katrin I Andreasson

Nat Immunol 2019 01 26;20(1):50-63. Epub 2018 Nov 26.

Department of Neurology & Neurological Sciences, Stanford School of Medicine, Stanford, CA, USA.

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January 2019

Mortal engines: Mitochondrial bioenergetics and dysfunction in neurodegenerative diseases.

Authors:
Amit U Joshi Daria Mochly-Rosen

Pharmacol Res 2018 12 23;138:2-15. Epub 2018 Aug 23.

Department of Chemical and Systems Biology, School of Medicine, Stanford University, CA, 94305-5174, USA. Electronic address:

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December 2018

Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease.

Authors:
Amit U Joshi Nay L Saw Mehrdad Shamloo Daria Mochly-Rosen

Oncotarget 2018 Jan 22;9(5):6128-6143. Epub 2017 Dec 22.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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January 2018

Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis.

Authors:
Amit U Joshi Nay L Saw Hannes Vogel Anna D Cunnigham Mehrdad Shamloo Daria Mochly-Rosen

EMBO Mol Med 2018 03;10(3)

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA, USA

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March 2018

The Role of Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) in Neuropathology and Neurodegeneration.

Authors:
Che-Hong Chen Amit U Joshi Daria Mochly-Rosen

Acta Neurol Taiwan 2016 Dec;25(4):111-123

Department of Chemical and Systems Biology, Stanford University, School of Medicine, Stanford CA 94305-5174 USA.

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December 2016

Potential biomarkers to follow the progression and treatment response of Huntington's disease.

Authors:
Marie-Hélène Disatnik Amit U Joshi Nay L Saw Mehrdad Shamloo Blair R Leavitt Xin Qi Daria Mochly-Rosen

J Exp Med 2016 11 7;213(12):2655-2669. Epub 2016 Nov 7.

Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305

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November 2016

The entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained.

Authors:
Amit U Joshi Opher S Kornfeld Daria Mochly-Rosen

Cell Calcium 2016 09 7;60(3):218-34. Epub 2016 May 7.

Department of Chemical & Systems Biology, School of Medicine, Stanford University, CA, USA. Electronic address:

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September 2016

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death.

Authors:
Nir Qvit Amit U Joshi Anna D Cunningham Julio C B Ferreira Daria Mochly-Rosen

J Biol Chem 2016 Jun 27;291(26):13608-21. Epub 2016 Apr 27.

From the Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, California 94305-5174 and

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June 2016