Amir T Fathi

Amir T Fathi

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Amir T Fathi

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Cardiac and genetic predictors of cardiovascular risk in patients with myelodysplastic syndromes.

Leuk Lymphoma 2019 May 23:1-5. Epub 2019 May 23.

c Center for Leukemia , Massachusetts General Hospital , Boston , MA , USA.

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http://dx.doi.org/10.1080/10428194.2019.1617863DOI Listing
May 2019

Clustered incidence of adult acute promyelocytic leukemia.

Leuk Res 2018 11 19;74:47-50. Epub 2018 Sep 19.

Massachusetts General Hospital, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.leukres.2018.09.008DOI Listing
November 2018

Lenalidomide combined with mismatched microtransplantation for acute myeloid leukemia.

Am J Hematol 2018 10 14;93(10):E331-E333. Epub 2018 Aug 14.

Division of Medical Oncology, Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajh.25218DOI Listing
October 2018

Impact of lenalidomide use among non-transfusion dependent patients with myelodysplastic syndromes.

Am J Hematol 2018 09 28;93(9):1119-1126. Epub 2018 Aug 28.

Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajh.25166DOI Listing
September 2018

Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML.

N Engl J Med 2018 Jun 2;378(25):2386-2398. Epub 2018 Jun 2.

From the University of Texas M.D. Anderson Cancer Center, Houston (C.D.D., H.M.K.); Memorial Sloan Kettering Cancer Center (E.M.S., M.S.T.) and Weill Cornell Medical College (G.J.R.), New York; Institut Gustave Roussy, Villejuif (S.B., C.W.), and Centre Hospitalier Universitaire Bordeaux, Bordeaux (A.P.) - both in France; Northwestern University, Chicago (J.K.A.); Ohio State University Wexner Medical Center, Columbus (A.S.M.); Sylvester Comprehensive Cancer Center, University of Miami, Miami (R.S.); University of Texas Southwestern Medical Center, Dallas (R.H.C.); University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco (G.N.M.), and City of Hope Medical Center, Duarte (A.S.S.) - both in California; University of Colorado School of Medicine, Aurora (D.A.P.); Sarah Cannon Research Institute, Nashville (W.D.); Massachusetts General Hospital Cancer Center (A.T.F.) and Dana-Farber Cancer Institute (R.M.S.), Boston, and Agios Pharmaceuticals, Cambridge (S.C., H.W., V.Z., K.E.Y., S.M.K., H.Y., D.D., B.F., M.G., H.L., S.A., B.W., E.C.A.) - all in Massachusetts; University of Alabama at Birmingham, Birmingham (H.P.E.); Johns Hopkins University, Baltimore (G.T.P.); Washington University School of Medicine, St. Louis (G.L.U.); Mayo Clinic, Jacksonville, FL (J.M.F.); Oregon Health and Science University Knight Cancer Institute, Portland (E.T.); Hollings Cancer Center, Medical University of South Carolina, Charleston (R.K.S.); Winship Cancer Institute of Emory University, Atlanta (M.L.A.); Mayo Clinic, Phoenix, AZ (J.L.S.); and Cleveland Clinic, Cleveland (M.A.S.).

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http://dx.doi.org/10.1056/NEJMoa1716984DOI Listing
June 2018

Reformulating acute myeloid leukemia: liposomal cytarabine and daunorubicin (CPX-351) as an emerging therapy for secondary AML.

Onco Targets Ther 2018 12;11:3425-3434. Epub 2018 Jun 12.

Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.2147/OTT.S141212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003284PMC
June 2018

Incident adverse events following therapy for acute promyelocytic leukemia.

Leuk Res Rep 2018 5;9:79-83. Epub 2018 May 5.

Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.lrr.2018.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993355PMC
May 2018

Early infectious complications among patients treated with induction compared to hypomethylating therapy for acute myeloid leukemia.

Leuk Lymphoma 2018 04 9;59(4):988-991. Epub 2017 Aug 9.

a Division of Hematology/Oncology , Massachusetts General Hospital, Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/10428194.2017.1361028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197051PMC
April 2018

Induction chemotherapy in acute myeloid leukaemia: origins and emerging directions.

Curr Opin Hematol 2018 03;25(2):67-74

Division of Hematology/Oncology, Massachusetts General Hospital.

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http://dx.doi.org/10.1097/MOH.0000000000000407DOI Listing
March 2018

Pevonedistat, a new partner for 5-azacitidine.

Authors:
Amir T Fathi

Blood 2018 03;131(13):1391-1392

Massachusetts General Hospital; Harvard Medical School.

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http://dx.doi.org/10.1182/blood-2018-02-829051DOI Listing
March 2018

Acute Leukemia is Associated with Cardiac Alterations before Chemotherapy.

J Am Soc Echocardiogr 2017 Nov 15;30(11):1111-1118. Epub 2017 Sep 15.

Cardiac Ultrasound Laboratory, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Cardiac Ultrasound Laboratory, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.echo.2017.07.016DOI Listing
November 2017

Isocitrate dehydrogenase (IDH) inhibition as treatment of myeloid malignancies: Progress and future directions.

Pharmacol Ther 2017 Sep 14;177:123-128. Epub 2017 Mar 14.

Department of Hematology/Oncology, Massachusetts General Hospital, Boston, MA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01637258173008
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http://dx.doi.org/10.1016/j.pharmthera.2017.03.003DOI Listing
September 2017

Bone marrow response as a potential biomarker of outcomes in glioblastoma patients.

J Neurosurg 2017 Jul 14;127(1):132-138. Epub 2016 Oct 14.

Harvard Medical School; and.

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http://dx.doi.org/10.3171/2016.7.JNS16609DOI Listing
July 2017

The role of FLT3 inhibitors in the treatment of FLT3-mutated acute myeloid leukemia.

Eur J Haematol 2017 Apr 19;98(4):330-336. Epub 2017 Jan 19.

Division of Hematology/Oncology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1111/ejh.12841DOI Listing
April 2017

Case 37-2016. An 86-Year-Old Woman with Leukocytosis and Splenomegaly.

N Engl J Med 2016 12;375(23):2273-2282

From the Departments of Medicine (A.T.F., T.A.G.), Radiology (N.M.K.), and Pathology (R.P.H.), Massachusetts General Hospital, the Department of Pathology, Brigham and Women's Hospital (F.C.K.), and the Departments of Medicine (A.T.F., T.A.G.), Radiology (N.M.K.), and Pathology (F.C.K., R.P.H.), Harvard Medical School - all in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1509539DOI Listing
December 2016

In Reply.

Oncologist 2016 08;21(8):1026

Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1634/theoncologist.2016-0138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978561PMC
August 2016

The Approach to Acute Lymphoblastic Leukemia in Older Patients: Conventional Treatments and Emerging Therapies.

Curr Hematol Malig Rep 2016 06;11(3):165-74

Harvard Medical School, Massachusetts General Hospital, Division of Hematology and Medical Oncology, Zero Emerson Place, Suite 118, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s11899-016-0316-3DOI Listing
June 2016

Potentially avoidable hospital admissions in older patients with acute myeloid leukaemia in the USA: a retrospective analysis.

Lancet Haematol 2016 Jun 18;3(6):e276-83. Epub 2016 May 18.

Bone Marrow Transplant Program, Department of Hematology and Oncology, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/S2352-3026(16)30024-2DOI Listing
June 2016

Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma.

Oncologist 2016 Feb 1;21(2):214-9. Epub 2016 Feb 1.

Division of Neuro-Oncology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA Division of Hematology/Oncology, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1634/theoncologist.2015-0342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746092PMC
February 2016

New molecular abnormalities and clonal architecture in AML: from reciprocal translocations to whole-genome sequencing.

Am Soc Clin Oncol Educ Book 2014 :e334-40

From the Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.e334DOI Listing
December 2015

Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia.

Leuk Res 2015 Oct 28;39(10):1034-40. Epub 2015 Jun 28.

Department of Pathology, Massachusetts General Hospital, United States. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2015.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764101PMC
October 2015

Biochemical, Epigenetic, and Metabolic Approaches to Target IDH Mutations in Acute Myeloid Leukemia.

Semin Hematol 2015 Jul 17;52(3):165-71. Epub 2015 Mar 17.

University of Maryland, School of Medicine, Marlene and Stewart Greenebaum Cancer Center, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2015.03.002DOI Listing
July 2015

Acute myeloid leukemia in a patient with constitutional 47,XXY karyotype.

Leuk Res Rep 2015 22;4(1):28-30. Epub 2015 Apr 22.

Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.1016/j.lrr.2015.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4421110PMC
May 2015

Chromosome 17p deletion in a case of T-cell acute lymphoblastic lymphoma.

Am J Hematol 2015 Mar 26;90(3):267-8. Epub 2014 Sep 26.

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajh.23847DOI Listing
March 2015

Myelodysplastic syndromes, version 2.2015.

J Natl Compr Canc Netw 2015 Mar;13(3):261-72

From Stanford Cancer Institute; Dana-Farber/Brigham and Women's Cancer Center; UC San Diego Moores Cancer Center; University of Rochester Medical Center; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; University of Alabama at Birmingham Comprehensive Cancer Center; Duke Cancer Institute; Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; Massachusetts General Hospital Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; UCSF Helen Diller Family Comprehensive Cancer Center; The University of Texas MD Anderson Cancer Center; Roswell Park Cancer Institute; Vanderbilt-Ingram Cancer Center; Memorial Sloan Kettering Cancer Center; Moffitt Cancer Center; University of Michigan Comprehensive Cancer Center; Fred & Pamela Buffett Cancer Center; City of Hope Comprehensive Cancer Center; University of Colorado Cancer Center; Huntsman Cancer Institute at the University of Utah; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; and National Comprehensive Cancer Network.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696005PMC
March 2015

Treatment of relapse of acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation.

Curr Hematol Malig Rep 2014 Jun;9(2):186-92

Center for Leukemia, Massachusetts General Hospital, Zero Emerson Place, Suite 118, Boston, MA, 02114, USA,

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http://dx.doi.org/10.1007/s11899-014-0209-2DOI Listing
June 2014

The evolving role of FLT3 inhibitors in acute myeloid leukemia: quizartinib and beyond.

Ther Adv Hematol 2014 Jun;5(3):65-77

Massachusetts General Hospital, Harvard Medical School, Zero Emerson Place, Suite 118, Boston, MA 02114, USA.

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http://dx.doi.org/10.1177/2040620714532123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031904PMC
June 2014

Inhibition of glutaminase selectively suppresses the growth of primary acute myeloid leukemia cells with IDH mutations.

Exp Hematol 2014 Apr 11;42(4):247-51. Epub 2013 Dec 11.

Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.exphem.2013.12.001DOI Listing
April 2014

CD30: a new target for ALL?

Leuk Lymphoma 2014 Mar 13;55(3):478-9. Epub 2013 Aug 13.

Massachusetts General Hospital Cancer Center, Harvard Medical School , Boston, MA , USA.

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http://dx.doi.org/10.3109/10428194.2013.823496DOI Listing
March 2014

Chronic Myelogenous Leukemia, Version 1.2014.

J Natl Compr Canc Netw 2013 Nov;11(11):1327-40

From 1The University of Texas MD Anderson Cancer Center; 2Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance; 3Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; 4Fred & Pamela Buffett Cancer Center at The Nebraska Medical Center; 5Robert H. Lurie Comprehensive Cancer Center of Northwestern University; 6Memorial Sloan-Kettering Cancer Center; 7Dana-Farber/Brigham & Women's Cancer Center; 8Huntsman Cancer Institute at the University of Utah; 9The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; 10Massachusetts General Hospital Cancer Center; 11Stanford Cancer Institute; 12Vanderbilt-Ingram Cancer Center; 13Fox Chase Cancer Center; 14Duke Cancer Institute; 15St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; 16Moffitt Cancer Center; 17University of Alabama at Birmingham Comprehensive Cancer Center; 18UCSF Helen Diller Family Comprehensive Cancer Center; 19The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; 20City of Hope Comprehensive Cancer Center; 21Roswell Park Cancer Institute; and 22National Comprehensive Cancer Network.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4234105PMC
November 2013

Emergence of crenolanib for FLT3-mutant AML.

Authors:
Amir T Fathi

Blood 2013 Nov;122(22):3547-8

HARVARD MEDICAL SCHOOL.

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http://dx.doi.org/10.1182/blood-2013-10-528992DOI Listing
November 2013

The evolving landscape in the therapy of acute myeloid leukemia.

Protein Cell 2013 Oct 27;4(10):735-46. Epub 2013 Aug 27.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s13238-013-3057-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4875431PMC
October 2013

Trends in all-cause mortality among patients with chronic myeloid leukemia: a Surveillance, Epidemiology, and End Results database analysis.

Cancer 2013 Jul 26;119(14):2620-9. Epub 2013 Apr 26.

Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/cncr.28106DOI Listing
July 2013

FLT3 inhibitor-induced neutrophilic dermatosis.

Blood 2013 Jul 17;122(2):239-42. Epub 2013 May 17.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1182/blood-2013-01-478172DOI Listing
July 2013

Clinicopathologic analysis of acute myeloid leukemia arising from chronic myelomonocytic leukemia.

Mod Pathol 2013 Jun 11;26(6):751-61. Epub 2013 Jan 11.

Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1038/modpathol.2012.218DOI Listing
June 2013

Pure erythroid leukemia evolving from a therapy-related myelodysplastic syndrome secondary to treatment for chronic lymphocytic leukemia.

Am J Hematol 2013 Mar 6;88(3):240-1. Epub 2012 May 6.

Department of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1002/ajh.23224
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http://dx.doi.org/10.1002/ajh.23224DOI Listing
March 2013

Infectious pathogens and hematologic malignancy.

Discov Med 2012 Dec;14(79):421-33

Center for Leukemia and the Bone Marrow Transplant Unit, Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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December 2012

Treatment of FLT3-ITD acute myeloid leukemia.

Am J Blood Res 2011 9;1(2):175-89. Epub 2011 Sep 9.

Center for Leukemia and the Bone Marrow Transplant Unit, Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School Boston, MA 02114, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3301423PMC
August 2012

Case records of the Massachusetts General Hospital. Case 24-2012. A 38-year-old man with abdominal pain and altered mental status.

N Engl J Med 2012 Aug;367(6):552-63

Division of Hematology and Medical Oncology and the Department of Medicine, Massachusetts General Hospital, Boston, USA.

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http://dx.doi.org/10.1056/NEJMcpc1110049DOI Listing
August 2012

Bilateral ear swelling and erythema after chemotherapy: a case of ara-C ears.

J Clin Oncol 2012 Jun 16;30(16):e146. Epub 2012 Apr 16.

Massachusetts General Hospital/Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1200/JCO.2011.39.5970DOI Listing
June 2012

FLT3 inhibition as therapy in acute myeloid leukemia: a record of trials and tribulations.

Oncologist 2011 17;16(8):1162-74. Epub 2011 Jul 17.

Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1634/theoncologist.2011-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228152PMC
February 2012

Hypereosinophilia in relapsed acute myeloid leukaemia.

Br J Haematol 2012 Jan 2;156(1). Epub 2011 Aug 2.

Department of Clinical and Experimental Medicine, Hematology and Clinical Immunology, University of Padua School of Medicine, Padua, Italy.

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http://dx.doi.org/10.1111/j.1365-2141.2011.08804.xDOI Listing
January 2012

Molecular alterations underlying eosinophilic and mast cell malignancies.

Discov Med 2011 Dec;12(67):481-93

Center for Leukemia and the Bone Marrow Transplant Unit, Division of Hematology/Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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December 2011

Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy.

Adv Hematol 2012 26;2012:469592. Epub 2011 Jun 26.

Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1155/2012/469592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145345PMC
November 2011

Exploiting cellular pathways to develop new treatment strategies for AML.

Cancer Treat Rev 2010 Apr 6;36(2):142-50. Epub 2010 Jan 6.

Division of Hematologic Malignancies, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, 1650 Orleans Street, Baltimore, MD 21231, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03057372090018
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http://dx.doi.org/10.1016/j.ctrv.2009.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839044PMC
April 2010

New agents in acute myeloid leukemia: beyond cytarabine and anthracyclines.

Curr Oncol Rep 2009 Sep;11(5):346-52

Division of Hematologic Malignancies, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, 1650 Orleans Street, CRB 1 Room 289, Baltimore, MD 21231, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066101PMC
September 2009

Chemotherapy for advanced stage non-small cell lung cancer.

Semin Thorac Cardiovasc Surg 2008 ;20(3):210-6

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231-1000, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S104306790800109
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http://dx.doi.org/10.1053/j.semtcvs.2008.09.002DOI Listing
March 2009

Lestaurtinib: a multi-targeted FLT3 inhibitor.

Expert Rev Hematol 2009 Feb;2(1):17-26

Department of Oncology, Division of Hematologic Malignancies, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1586/17474086.2.1.17DOI Listing
February 2009