Amir Goldkorn

Amir Goldkorn

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Amir Goldkorn

Amir Goldkorn

Publications by authors named "Amir Goldkorn"

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32Publications

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Epigenetic plasticity potentiates a rapid cyclical shift to and from an aggressive cancer phenotype.

Int J Cancer 2020 Feb 3. Epub 2020 Feb 3.

Division of Medical Oncology, Department of Internal Medicine, University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, Los Angeles, CA.

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http://dx.doi.org/10.1002/ijc.32904DOI Listing
February 2020

Cancer transcriptomic profiling from rapidly enriched circulating tumor cells.

Int J Cancer 2020 Feb 9. Epub 2020 Feb 9.

Department of Medicine, University of Southern California (USC), Keck School of Medicine and Norris Comprehensive Cancer Center (NCCC), Los Angeles, California, USA.

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http://dx.doi.org/10.1002/ijc.32915DOI Listing
February 2020

Randomized Phase II Trial of Abiraterone Alone or With Dasatinib in Men With Metastatic Castration-resistant Prostate Cancer (mCRPC).

Clin Genitourin Cancer 2019 08 19;17(4):241-247.e1. Epub 2019 Mar 19.

Lawrence J. Ellison Institute for Transformative Medicine of USC and Norris Comprehensive Cancer Center, USC Keck School of Medicine, Los Angeles, CA.

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http://dx.doi.org/10.1016/j.clgc.2019.02.010DOI Listing
August 2019

Liquid Biopsy in Prostate Cancer: Circulating Tumor Cells and Beyond.

Cancer Treat Res 2018;175:87-104

USC Keck/Norris Comprehensive Cancer Center, Los Angeles, CA, USA.

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http://link.springer.com/10.1007/978-3-319-93339-9_4
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http://dx.doi.org/10.1007/978-3-319-93339-9_4DOI Listing
June 2019

Current status of liquid biopsies for the detection and management of prostate cancer.

Cancer Manag Res 2019 6;11:5271-5291. Epub 2019 Jun 6.

Division of Medical Oncology, Department of Medicine, Keck School of Medicine and Translational and Clinical Science Program, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.2147/CMAR.S170380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6559244PMC
June 2019

Development and Application of Liquid Biopsies in Metastatic Prostate Cancer.

Curr Oncol Rep 2018 03 23;20(4):35. Epub 2018 Mar 23.

Division of Medical Oncology, Department of Medicine, Keck School of Medicine and Translational and Clinical Science Program, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s11912-018-0683-0DOI Listing
March 2018

Circulating Tumor Cells in Genitourinary Malignancies: An Evolving Path to Precision Medicine.

Front Oncol 2017 27;7. Epub 2017 Jan 27.

Keck School of Medicine and Norris Comprehensive Cancer Center, Medicine , Los Angeles, CA , USA.

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http://dx.doi.org/10.3389/fonc.2017.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5269447PMC
January 2017

AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth.

Prostate 2016 May 15;76(6):597-608. Epub 2016 Jan 15.

Division of Medical Oncology, Department of Medicine, University of Southern California Keck School of Medicine and Translational and Clinical Science Program, USC Norris Comprehensive Cancer Center, Los Angeles, California.

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http://dx.doi.org/10.1002/pros.23151DOI Listing
May 2016

Telomere and Telomerase Therapeutics in Cancer.

Genes (Basel) 2016 May 26;7(6). Epub 2016 May 26.

Division of Medical Oncology, Department of Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.3390/genes7060022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4929421PMC
May 2016

Editorial Comment.

Authors:
Amir Goldkorn

J Urol 2015 Sep 10;194(3):798. Epub 2015 Jun 10.

Section of Genitourinary Oncology, Division of Medical Oncology, Department of Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1016/j.juro.2015.02.2961DOI Listing
September 2015

Exosome-mediated transfer of microRNAs within the tumor microenvironment and neuroblastoma resistance to chemotherapy.

J Natl Cancer Inst 2015 Jul 13;107(7). Epub 2015 May 13.

Children's Center for Cancer and Blood Diseases and The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA; and Departments of Pediatrics and Molecular Microbiology & Immunology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA (KBC, PMW, PN, HC, MM, MF); Division of Medical Oncology, Department of Internal Medicine, University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, Los Angeles, CA (TX, AG); Division of Hematology/Oncology, Children's Hospital Los Angeles, Los Angeles, CA (RK, MH, AJ, RCS, SA); Departments of Experimental Therapeutics and Leukemia and The Center for RNA interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX (CI, GAC); Department of Gynecologic Oncology and Reproductive Medicine and The Center for RNA interference and Non-Coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, TX (XZ); Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) s.r.l., IRCCS, Gene Therapy Unit, Meldola (FC) 47014, Italy (IV, FF, DA); Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA (HS, SA).

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http://dx.doi.org/10.1093/jnci/djv135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651042PMC
July 2015

Circulating tumor cells in prostate cancer: a better predictor of survival than prostate specific antigen?

Expert Rev Anticancer Ther 2014 Nov 9;14(11):1257-60. Epub 2014 Sep 9.

Institute of Urology, Keck Medical Center of USC, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1586/14737140.2014.957190DOI Listing
November 2014

New prostate cancer drugs: extending and improving life.

Lancet Oncol 2014 Sep 4;15(10):1052-4. Epub 2014 Aug 4.

University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(14)70332-8DOI Listing
September 2014

Serum biomarkers of bone metabolism in castration-resistant prostate cancer patients with skeletal metastases: results from SWOG 0421.

J Natl Cancer Inst 2014 Apr 24;106(4):dju013. Epub 2014 Feb 24.

Affiliations of authors: University of California Davis Comprehensive Cancer Center, Sacramento, CA (PNL, PCM); Southwest Oncology Group Statistical Center, Seattle, WA (BE, CT); University of Southern California Norris Cancer Center, Los Angeles, CA (DIQ, AG); USDA Western Human Nutrition Center at University of California Davis, Davis, CA (EG, MVL); City of Hope, Duarte, CA (PT); University of Michigan, Ann Arbor, MI (MH), US Oncology, Las Vegas, NV (NJV); Cancer Treatment and Research Center, University of Texas, San Antonio, TX (IT).

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http://dx.doi.org/10.1093/jnci/dju013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982883PMC
April 2014

Circulating tumor cell counts are prognostic of overall survival in SWOG S0421: a phase III trial of docetaxel with or without atrasentan for metastatic castration-resistant prostate cancer.

J Clin Oncol 2014 Apr 10;32(11):1136-42. Epub 2014 Mar 10.

Amir Goldkorn, David I. Quinn, and Tong Xu, University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, Los Angeles; Przemyslaw Twardowski, City of Hope, Duarte; Philip C. Mack and Primo Lara Jr, University of California, Davis, Sacramento, CA; Benjamin Ely and Catherine M. Tangen, Southwest Oncology Group Statistical Center; Celestia S. Higano, Puget Sound Oncology Consortium, Seattle Cancer Care Alliance, and University of Washington, Seattle, WA; Louis M. Fink, Nevada Cancer Institute; Nicholas J. Vogelzang, Comprehensive Cancer Centers of Nevada and US Oncology Research, Las Vegas, NV; Peter J. Van Veldhuizen, University of Kansas Cancer Center, Westwood, KS; Neeraj Agarwal, University of Utah Huntsman Cancer Institute, Salt Lake City, UT; Michael A. Carducci, Johns Hopkins Kimmel Cancer Center and Eastern Cooperative Oncology Group, Baltimore, MD; J. Paul Monk III, Ohio State University and Cancer and Leukemia Group B, Columbus, OH; Ram H. Datar and Richard J. Cote, University of Miami Miller School of Medicine, Miami, FL; Mark Garzotto, Portland Veterans Affairs Medical Center, Portland, OR; Maha Hussain, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; and Ian Murchie Thompson Jr, University of Texas Health Science Center at San Antonio, San Antonio, TX.

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http://dx.doi.org/10.1200/JCO.2013.51.7417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970171PMC
April 2014

Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.

Int J Cancer 2014 Jan 5;134(1):43-54. Epub 2013 Aug 5.

Division of Medical Oncology, Department of Internal Medicine, University of Southern California Keck School of Medicine, Los Angeles, California.

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http://dx.doi.org/10.1002/ijc.28341DOI Listing
January 2014

Efficacy of oxaliplatin plus pemetrexed in chemotherapy pretreated metastatic castration-resistant prostate cancer.

Clin Genitourin Cancer 2013 Dec 4;11(4):416-22. Epub 2013 Oct 4.

University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA.

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http://dx.doi.org/10.1016/j.clgc.2013.07.011DOI Listing
December 2013

Circulating tumor cells in prostate cancer.

Cancers (Basel) 2013 Dec 4;5(4):1676-90. Epub 2013 Dec 4.

Institute of Urology, University of Southern California, 1441 Eastlake Avenue, Suite 7416, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.3390/cancers5041676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875960PMC
December 2013

Perillyl alcohol for the treatment of temozolomide-resistant gliomas.

Mol Cancer Ther 2012 Nov 28;11(11):2462-72. Epub 2012 Aug 28.

Departments of Neurosurgery and Pathology, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0321DOI Listing
November 2012

Prostate tumor cells with cancer progenitor properties have high telomerase activity and are rapidly killed by telomerase interference.

Prostate 2011 Sep 14;71(13):1390-400. Epub 2011 Feb 14.

Division of Medical Oncology, Department of Internal Medicine, University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, Los Angeles, California, USA.

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http://doi.wiley.com/10.1002/pros.21355
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http://dx.doi.org/10.1002/pros.21355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123672PMC
September 2011

Cancer cells cyclically lose and regain drug-resistant highly tumorigenic features characteristic of a cancer stem-like phenotype.

Mol Cancer Ther 2011 Jun 25;10(6):938-48. Epub 2011 Apr 25.

Division of Medical Oncology, Department of Internal Medicine, University of Southern California Keck School of Medicine and Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Suite 3440, Los Angeles, CA 90033, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-10
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http://dx.doi.org/10.1158/1535-7163.MCT-10-1120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112267PMC
June 2011

Telomerase targeted therapy in cancer and cancer stem cells.

Clin Adv Hematol Oncol 2011 Jun;9(6):442-55

Division of Medical Oncology, Department of Internal Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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June 2011

A cancer detection platform which measures telomerase activity from live circulating tumor cells captured on a microfilter.

Cancer Res 2010 Aug 27;70(16):6420-6. Epub 2010 Jul 27.

Division of Medical Oncology, Department of Internal Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-10-0686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922429PMC
August 2010

Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo.

Mol Cancer Ther 2010 Feb 2;9(2):438-49. Epub 2010 Feb 2.

Division of Medical Oncology, Department of Internal Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-09
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http://dx.doi.org/10.1158/1535-7163.MCT-09-0682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820598PMC
February 2010

Targeted therapy in renal cancer.

Ther Adv Med Oncol 2009 Nov;1(3):183-205

Assistant Professors of Medicine, Kenneth J. Norris Comprehensive Cancer Center, Section of Genitourinary Medical Oncology, Division of Cancer Medicine and Blood Diseases, University of Southern California, Los Angeles CA, USA.

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http://dx.doi.org/10.1177/1758834009349119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125999PMC
November 2009

Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.

Cancer Res 2006 Jun;66(11):5763-71

Department of Internal Medicine, Division of Hematology and Oncology, University of California at San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-3782DOI Listing
June 2006