Amelia K Pinto

Amelia K Pinto

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Amelia K Pinto

Amelia K Pinto

Publications by authors named "Amelia K Pinto"

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The small molecule AZD6244 inhibits dengue virus replication in vitro and protects against lethal challenge in a mouse model.

Arch Virol 2020 Mar 16;165(3):671-681. Epub 2020 Jan 16.

Grupo de Transdução de Sinal/Flavivírus, Laboratório de Vírus, Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, Campus Pampulha, Belo Horizonte, MG, 31270-901, Brazil.

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http://dx.doi.org/10.1007/s00705-020-04524-7DOI Listing
March 2020

Isolation and Quantification of Zika Virus from Multiple Organs in a Mouse.

J Vis Exp 2019 Aug 15(150). Epub 2019 Aug 15.

Department of Molecular Microbiology and Immunology, Saint Louis University;

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http://dx.doi.org/10.3791/59632DOI Listing
August 2019

Identification of Protective CD8 T Cell Responses in a Mouse Model of Zika Virus Infection.

Front Immunol 2019 17;10:1678. Epub 2019 Jul 17.

Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, MO, United States.

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http://dx.doi.org/10.3389/fimmu.2019.01678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652237PMC
July 2019

Mouse Models of Heterologous Flavivirus Immunity: A Role for Cross-Reactive T Cells.

Front Immunol 2019 9;10:1045. Epub 2019 May 9.

Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, MO, United States.

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http://dx.doi.org/10.3389/fimmu.2019.01045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520664PMC
May 2019

CD4+T cells mediate protection against Zika associated severe disease in a mouse model of infection.

PLoS Pathog 2018 09 13;14(9):e1007237. Epub 2018 Sep 13.

Department of Molecular Microbiology and Immunology, Saint Louis University, St Louis, Missouri, United States of America.

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http://dx.plos.org/10.1371/journal.ppat.1007237
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http://dx.doi.org/10.1371/journal.ppat.1007237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136803PMC
September 2018

Residues in the PB2 and PA genes contribute to the pathogenicity of avian H7N3 influenza A virus in DBA/2 mice.

Virology 2016 07 20;494:89-99. Epub 2016 Apr 20.

Departments of Internal Medicine, Molecular Microbiology, and Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2016.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551402PMC
July 2016

A North American H7N3 Influenza Virus Supports Reassortment with 2009 Pandemic H1N1 and Induces Disease in Mice without Prior Adaptation.

J Virol 2016 May 14;90(9):4796-4806. Epub 2016 Apr 14.

Departments of Internal Medicine, Molecular Microbiology and Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA

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http://dx.doi.org/10.1128/JVI.02761-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836326PMC
May 2016

Interferon-Regulatory Factor 5-Dependent Signaling Restricts Orthobunyavirus Dissemination to the Central Nervous System.

J Virol 2016 01 14;90(1):189-205. Epub 2015 Oct 14.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, USA Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, USA

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http://dx.doi.org/10.1128/JVI.02276-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702527PMC
January 2016

Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families.

J Virol 2015 Sep 8;89(18):9465-76. Epub 2015 Jul 8.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

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http://dx.doi.org/10.1128/JVI.00996-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542382PMC
September 2015

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection.

mBio 2015 Sep 15;6(5):e01316-15. Epub 2015 Sep 15.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, USA

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http://dx.doi.org/10.1128/mBio.01316-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600115PMC
September 2015

Oropouche virus infection and pathogenesis are restricted by MAVS, IRF-3, IRF-7, and type I interferon signaling pathways in nonmyeloid cells.

J Virol 2015 May 25;89(9):4720-37. Epub 2015 Feb 25.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, USA Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, USA

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http://dx.doi.org/10.1128/JVI.00077-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403474PMC
May 2015

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier.

Sci Transl Med 2015 Apr;7(284):284ra59

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://stm.sciencemag.org/lookup/doi/10.1126/scitranslmed.aa
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http://dx.doi.org/10.1126/scitranslmed.aaa4304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435724PMC
April 2015

Interferon regulatory factor 5-dependent immune responses in the draining lymph node protect against West Nile virus infection.

J Virol 2014 Oct 16;88(19):11007-21. Epub 2014 Jul 16.

Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri, USA Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA The Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, Saint Louis, Missouri, USA

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http://dx.doi.org/10.1128/JVI.01545-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178807PMC
October 2014

Deficient IFN signaling by myeloid cells leads to MAVS-dependent virus-induced sepsis.

PLoS Pathog 2014 Apr 17;10(4):e1004086. Epub 2014 Apr 17.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990718PMC
April 2014

Murine norovirus infection does not cause major disruptions in the murine intestinal microbiota.

Microbiome 2013 Feb 18;1(1). Epub 2013 Feb 18.

Department of Microbiology and Immunology, University of Michigan Medical School, 5622 Medical Sciences Bldg, II, 1150 West Medical Center Drive, 48109-5620, Ann Arbor, USA.

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http://microbiomejournal.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/2049-2618-1-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177540PMC
February 2013

CD8+ T cells use TRAIL to restrict West Nile virus pathogenesis by controlling infection in neurons.

J Virol 2012 Sep 27;86(17):8937-48. Epub 2012 Jun 27.

Departments of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1128/JVI.00673-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3416144PMC
September 2012

Comparing the kinetics of NK cells, CD4, and CD8 T cells in murine cytomegalovirus infection.

J Immunol 2011 Aug 22;187(3):1385-92. Epub 2011 Jun 22.

Complex Systems in Biology Group, Centre for Vascular Research, University of New South Wales, Kensington, New South Wales 2052, Australia.

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http://dx.doi.org/10.4049/jimmunol.1100416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771860PMC
August 2011

Beta interferon controls West Nile virus infection and pathogenesis in mice.

J Virol 2011 Jul 4;85(14):7186-94. Epub 2011 May 4.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Avenue, Box 8051, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.00396-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126609PMC
July 2011

The lectin pathway of complement activation contributes to protection from West Nile virus infection.

Virology 2011 Mar 26;412(1):101-9. Epub 2011 Jan 26.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Ave., St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1016/j.virol.2011.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057364PMC
March 2011

Effects of acute and chronic murine norovirus infections on immune responses and recovery from Friend retrovirus infection.

J Virol 2009 Dec 7;83(24):13037-41. Epub 2009 Oct 7.

Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases,National Institutes of Health, Hamilton, Montana 59840, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.01445-09
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http://dx.doi.org/10.1128/JVI.01445-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786825PMC
December 2009

Murine norovirus infection has no significant effect on adaptive immunity to vaccinia virus or influenza A virus.

J Virol 2009 Jul 29;83(14):7357-60. Epub 2009 Apr 29.

Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 208921, USA.

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http://dx.doi.org/10.1128/JVI.00623-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704774PMC
July 2009

The role of NKG2D signaling in inhibition of cytotoxic T-lymphocyte lysis by the Murine cytomegalovirus immunoevasin m152/gp40.

J Virol 2007 Nov 12;81(22):12564-71. Epub 2007 Sep 12.

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA.

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http://jvi.asm.org/content/81/22/12564.full.pdf
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http://jvi.asm.org/cgi/doi/10.1128/JVI.01328-07
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http://dx.doi.org/10.1128/JVI.01328-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169000PMC
November 2007

Viral interference with antigen presentation does not alter acute or chronic CD8 T cell immunodominance in murine cytomegalovirus infection.

J Immunol 2007 Jun;178(11):7235-41

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.4049/jimmunol.178.11.7235DOI Listing
June 2007

Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis.

J Immunol 2006 Sep;177(5):3225-34

Oregon Health and Science University, Molecular Microbiology and Immunology, Portland, OR 97239, USA.

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http://dx.doi.org/10.4049/jimmunol.177.5.3225DOI Listing
September 2006

Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection.

J Immunol 2006 Jul;177(1):450-8

Department of Molecular Microbiology and Immunology, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.4049/jimmunol.177.1.450DOI Listing
July 2006

Murine cytomegalovirus interference with antigen presentation contributes to the inability of CD8 T cells to control virus in the salivary gland.

J Virol 2006 Apr;80(8):4200-2

Department of Molecular Microbiology and Immunology, L220, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA.

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http://jvi.asm.org/cgi/doi/10.1128/JVI.80.8.4200-4202.2006
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http://dx.doi.org/10.1128/JVI.80.8.4200-4202.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440476PMC
April 2006

Viral interference with antigen presentation to CD8+ T cells: lessons from cytomegalovirus.

Viral Immunol 2005 ;18(3):434-44

Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1089/vim.2005.18.434DOI Listing
December 2005

T cell immunodominance and maintenance of memory regulated by unexpectedly cross-reactive pathogens.

Nat Immunol 2002 Jul 3;3(7):627-34. Epub 2002 Jun 3.

Department of Pathology and Progranm in Immunology and Virology, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://www.nature.com/articles/ni806
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http://dx.doi.org/10.1038/ni806DOI Listing
July 2002