Publications by authors named "Amber M Smith"

63Publications

COVID-19 virtual patient cohort reveals immune mechanisms driving disease outcomes.

Authors:
Adrianne L Jenner Rosemary A Aogo Sofia Alfonso Vivienne Crowe Amanda P Smith Penelope A Morel Courtney L Davis Amber M Smith Morgan Craig

bioRxiv 2021 Jan 6. Epub 2021 Jan 6.

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January 2021

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.

Authors:
Michael Schoof Bryan Faust Reuben A Saunders Smriti Sangwan Veronica Rezelj Nick Hoppe Morgane Boone Christian B Billesbølle Cristina Puchades Caleigh M Azumaya Huong T Kratochvil Marcell Zimanyi Ishan Deshpande Jiahao Liang Sasha Dickinson Henry C Nguyen Cynthia M Chio Gregory E Merz Michael C Thompson Devan Diwanji Kaitlin Schaefer Aditya A Anand Niv Dobzinski Beth Shoshana Zha Camille R Simoneau Kristoffer Leon Kris M White Un Seng Chio Meghna Gupta Mingliang Jin Fei Li Yanxin Liu Kaihua Zhang David Bulkley Ming Sun Amber M Smith Alexandrea N Rizo Frank Moss Axel F Brilot Sergei Pourmal Raphael Trenker Thomas Pospiech Sayan Gupta Benjamin Barsi-Rhyne Vladislav Belyy Andrew W Barile-Hill Silke Nock Yuwei Liu Nevan J Krogan Corie Y Ralston Danielle L Swaney Adolfo García-Sastre Melanie Ott Marco Vignuzzi Peter Walter Aashish Manglik

Science 2020 12 5;370(6523):1473-1479. Epub 2020 Nov 5.

Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, USA.

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December 2020

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

Authors:
David E Gordon Joseph Hiatt Mehdi Bouhaddou Veronica V Rezelj Svenja Ulferts Hannes Braberg Alexander S Jureka Kirsten Obernier Jeffrey Z Guo Jyoti Batra Robyn M Kaake Andrew R Weckstein Tristan W Owens Meghna Gupta Sergei Pourmal Erron W Titus Merve Cakir Margaret Soucheray Michael McGregor Zeynep Cakir Gwendolyn Jang Matthew J O'Meara Tia A Tummino Ziyang Zhang Helene Foussard Ajda Rojc Yuan Zhou Dmitry Kuchenov Ruth Hüttenhain Jiewei Xu Manon Eckhardt Danielle L Swaney Jacqueline M Fabius Manisha Ummadi Beril Tutuncuoglu Ujjwal Rathore Maya Modak Paige Haas Kelsey M Haas Zun Zar Chi Naing Ernst H Pulido Ying Shi Inigo Barrio-Hernandez Danish Memon Eirini Petsalaki Alistair Dunham Miguel Correa Marrero David Burke Cassandra Koh Thomas Vallet Jesus A Silvas Caleigh M Azumaya Christian Billesbølle Axel F Brilot Melody G Campbell Amy Diallo Miles Sasha Dickinson Devan Diwanji Nadia Herrera Nick Hoppe Huong T Kratochvil Yanxin Liu Gregory E Merz Michelle Moritz Henry C Nguyen Carlos Nowotny Cristina Puchades Alexandrea N Rizo Ursula Schulze-Gahmen Amber M Smith Ming Sun Iris D Young Jianhua Zhao Daniel Asarnow Justin Biel Alisa Bowen Julian R Braxton Jen Chen Cynthia M Chio Un Seng Chio Ishan Deshpande Loan Doan Bryan Faust Sebastian Flores Mingliang Jin Kate Kim Victor L Lam Fei Li Junrui Li Yen-Li Li Yang Li Xi Liu Megan Lo Kyle E Lopez Arthur A Melo Frank R Moss Phuong Nguyen Joana Paulino Komal Ishwar Pawar Jessica K Peters Thomas H Pospiech Maliheh Safari Smriti Sangwan Kaitlin Schaefer Paul V Thomas Aye C Thwin Raphael Trenker Eric Tse Tsz Kin Martin Tsui Feng Wang Natalie Whitis Zanlin Yu Kaihua Zhang Yang Zhang Fengbo Zhou Daniel Saltzberg Anthony J Hodder Amber S Shun-Shion Daniel M Williams Kris M White Romel Rosales Thomas Kehrer Lisa Miorin Elena Moreno Arvind H Patel Suzannah Rihn Mir M Khalid Albert Vallejo-Gracia Parinaz Fozouni Camille R Simoneau Theodore L Roth David Wu Mohd Anisul Karim Maya Ghoussaini Ian Dunham Francesco Berardi Sebastian Weigang Maxime Chazal Jisoo Park James Logue Marisa McGrath Stuart Weston Robert Haupt C James Hastie Matthew Elliott Fiona Brown Kerry A Burness Elaine Reid Mark Dorward Clare Johnson Stuart G Wilkinson Anna Geyer Daniel M Giesel Carla Baillie Samantha Raggett Hannah Leech Rachel Toth Nicola Goodman Kathleen C Keough Abigail L Lind Reyna J Klesh Kafi R Hemphill Jared Carlson-Stevermer Jennifer Oki Kevin Holden Travis Maures Katherine S Pollard Andrej Sali David A Agard Yifan Cheng James S Fraser Adam Frost Natalia Jura Tanja Kortemme Aashish Manglik Daniel R Southworth Robert M Stroud Dario R Alessi Paul Davies Matthew B Frieman Trey Ideker Carmen Abate Nolwenn Jouvenet Georg Kochs Brian Shoichet Melanie Ott Massimo Palmarini Kevan M Shokat Adolfo García-Sastre Jeremy A Rassen Robert Grosse Oren S Rosenberg Kliment A Verba Christopher F Basler Marco Vignuzzi Andrew A Peden Pedro Beltrao Nevan J Krogan

Science 2020 12 15;370(6521). Epub 2020 Oct 15.

Quantitative Biosciences Institute (QBI) COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA.

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December 2020

Leveraging Computational Modeling to Understand Infectious Diseases.

Authors:
Adrianne L Jenner Rosemary A Aogo Courtney L Davis Amber M Smith Morgan Craig

Curr Pathobiol Rep 2020 Sep 24:1-13. Epub 2020 Sep 24.

Department of Mathematics and Statistics, Pavillon André-Aisenstadt, Université de Montréal, Montréal, QC H3C 3J7 Canada.

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September 2020

Vitamin A deficiency dysregulates immune responses toward influenza virus and increases mortality after bacterial coinfections.

Authors:
Rhiannon R Penkert Amanda P Smith Eike R Hrincius Jonathan A McCullers Peter Vogel Amber M Smith Julia L Hurwitz

J Infect Dis 2020 Sep 22. Epub 2020 Sep 22.

Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, Tennessee.

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September 2020

Rapid community-driven development of a SARS-CoV-2 tissue simulator.

Authors:
Yafei Wang Gary An Andrew Becker Chase Cockrell Nicholson Collier Morgan Craig Courtney L Davis James Faeder Ashlee N Ford Versypt Juliano F Gianlupi James A Glazier Randy Heiland Thomas Hillen Mohammad Aminul Islam Adrianne Jenner Bing Liu Penelope A Morel Aarthi Narayanan Jonathan Ozik Padmini Rangamani Jason Edward Shoemaker Amber M Smith Paul Macklin

bioRxiv 2020 Apr 5. Epub 2020 Apr 5.

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April 2020

Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial.

Authors:
Aditya H Gaur James S McCarthy John C Panetta Ronald H Dallas John Woodford Li Tang Amber M Smith Tracy B Stewart Kristen C Branum Burgess B Freeman Nehali D Patel Elizabeth John Stephan Chalon Shelley Ost Ryan N Heine Julie L Richardson Robbin Christensen Patricia M Flynn Yvonne Van Gessel Branko Mitasev Jörg J Möhrle Fabian Gusovsky Lidiya Bebrevska R Kiplin Guy

Lancet Infect Dis 2020 08 8;20(8):964-975. Epub 2020 Apr 8.

University of Kentucky College of Pharmacy, University of Kentucky, Lexington, KY, USA.

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August 2020

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.

Authors:
Katherine R Balka Cynthia Louis Tahnee L Saunders Amber M Smith Dale J Calleja Damian B D'Silva Fiona Moghaddas Maximilien Tailler Kate E Lawlor Yifan Zhan Christopher J Burns Ian P Wicks Jonathan J Miner Benjamin T Kile Seth L Masters Dominic De Nardo

Cell Rep 2020 04;31(1):107492

Inflammation Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3010, Australia; Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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April 2020

Reactions of Novice Interviewers Conducting Trauma Research With Marginalized Communities: A Qualitative Analysis.

Authors:
Amber M Smith Alison B Hamilton Tamra Loeb Jennifer Pemberton Gail E Wyatt

J Interpers Violence 2019 Dec 2:886260519889925. Epub 2019 Dec 2.

University of California, Los Angeles, USA.

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December 2019

PARAMETER AND UNCERTAINTY ESTIMATION FOR DYNAMICAL SYSTEMS USING SURROGATE STOCHASTIC PROCESSES.

Authors:
Matthias Chung Mickaël Binois Robert B Gramacy Johnathan M Bardsley David J Moquin Amanda P Smith Amber M Smith

SIAM J Sci Comput 2019 16;41(4):A2212-A2238. Epub 2019 Jul 16.

Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38103.

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July 2019

Validated Models of Immune Response to Virus Infection.

Authors:
Amber M Smith

Curr Opin Syst Biol 2018 Dec 31;12:46-52. Epub 2018 Oct 31.

University of Tennessee Health Science Center, Memphis, TN 38163 USA.

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December 2018

Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae.

Authors:
Angeline E Rodriguez Christopher Bogart Christopher M Gilbert Jonathan A McCullers Amber M Smith Thirumala-Devi Kanneganti Christopher R Lupfer

PLoS One 2019 22;14(2):e0212236. Epub 2019 Feb 22.

Department of Biology, Missouri State University, Springfield, Missouri, United States of America.

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November 2019

A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in Mice.

Authors:
Brock G Bennion Harshad Ingle Teresa L Ai Cathrine A Miner Derek J Platt Amber M Smith Megan T Baldridge Jonathan J Miner

J Virol 2019 02 5;93(4). Epub 2019 Feb 5.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA

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February 2019

Memory CD8 T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development.

Authors:
David O'Sullivan Gerritje J W van der Windt Stanley Ching-Cheng Huang Jonathan D Curtis Chih-Hao Chang Michael D Buck Jing Qiu Amber M Smith Wing Y Lam Lisa M DiPlato Fong-Fu Hsu Morris J Birnbaum Edward J Pearce Erika L Pearce

Immunity 2018 08;49(2):375-376

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August 2018

Host-pathogen kinetics during influenza infection and coinfection: insights from predictive modeling.

Authors:
Amber M Smith

Immunol Rev 2018 09;285(1):97-112

University of Tennessee Health Science Center, Memphis, TN, USA.

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September 2018

Influenza Virus Infection Model With Density Dependence Supports Biphasic Viral Decay.

Authors:
Amanda P Smith David J Moquin Veronika Bernhauerova Amber M Smith

Front Microbiol 2018 10;9:1554. Epub 2018 Jul 10.

Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, United States.

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July 2018

Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice.

Authors:
Derek J Platt Amber M Smith Nitin Arora Michael S Diamond Carolyn B Coyne Jonathan J Miner

Sci Transl Med 2018 01;10(426)

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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January 2018

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors.

Authors:
Jennifer M Binning Amber M Smith Judd F Hultquist Charles S Craik Nathalie Caretta Cartozo Melody G Campbell Lily Burton Florencia La Greca Michael J McGregor Hai M Ta Koen Bartholomeeusen B Matija Peterlin Nevan J Krogan Natalia Sevillano Yifan Cheng John D Gross

PLoS Pathog 2018 01 5;14(1):e1006830. Epub 2018 Jan 5.

Department of Pharmaceutical Chemistry, University of California, San Francisco, California, United States of America.

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January 2018

The Unexpected Impact of Vaccines on Secondary Bacterial Infections Following Influenza.

Authors:
Amber M Smith Victor C Huber

Viral Immunol 2018 03 17;31(2):159-173. Epub 2017 Nov 17.

2 Division of Basic Biomedical Sciences, University of South Dakota , Vermillion, South Dakota.

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March 2018

STING-associated vasculopathy develops independently of IRF3 in mice.

Authors:
James D Warner Ricardo A Irizarry-Caro Brock G Bennion Teresa L Ai Amber M Smith Cathrine A Miner Tomomi Sakai Vijay K Gonugunta Jianjun Wu Derek J Platt Nan Yan Jonathan J Miner

J Exp Med 2017 Nov 26;214(11):3279-3292. Epub 2017 Sep 26.

Department of Medicine, Washington University School of Medicine, St. Louis, MO

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November 2017