Amaya Azqueta

Amaya Azqueta

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Amaya Azqueta

Publications by authors named "Amaya Azqueta"

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Bioactive Compounds from Seaweed with Anti-Leukemic Activity: A Mini-Review on Carotenoids and Phlorotannins.

Mini Rev Med Chem 2020 ;20(1):39-53

Team of Histomorphology, Physiopathology and Applied Toxicology, CIIMAR/CIMAR - Interdisciplinary Center for Marine and Environmental Research, U.Porto - University of Porto, Avenida General Norton de Matos s/n, 4450-208 Matosinhos, Portugal.

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http://dx.doi.org/10.2174/1389557519666190311095655DOI Listing
February 2020

Genotoxicity of Silver Nanoparticles.

Nanomaterials (Basel) 2020 Jan 31;10(2). Epub 2020 Jan 31.

Department of Pharmacology and Toxicology, Faculty of Pharmacy and Nutrition, Universidad de Navarra, Irunlarrea 1, 31008 Pamplona, Spain.

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http://dx.doi.org/10.3390/nano10020251DOI Listing
January 2020

Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation.

Bioorg Med Chem 2019 Sep 19;27(17):3902-3917. Epub 2019 Jul 19.

Universidad de Navarra, Department of Pharmaceutical Technology and Chemistry, Instituto de Salud Tropical, Pamplona 31008, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.07.029DOI Listing
September 2019

The enzyme-modified comet assay: Enzyme incubation step in 2 vs 12-gels/slide systems.

Mutat Res 2019 Sep 22;845:402981. Epub 2018 Nov 22.

Department of Pharmacology and Toxicology, University of Navarra, C/Irunlarrea 1, 31009 Pamplona, Spain; IdiSNA, Navarra Institute for Health Research, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2018.11.005DOI Listing
September 2019

Technical recommendations to perform the alkaline standard and enzyme-modified comet assay in human biomonitoring studies.

Mutat Res 2019 Jul 1;843:24-32. Epub 2019 May 1.

Department of Nutrition, Institute for Basic Medical Sciences, University of Oslo, Sognsvannsveien 9, 0372 Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2019.04.007DOI Listing
July 2019

DNA repair as a human biomonitoring tool: Comet assay approaches.

Mutat Res 2019 Jul - Sep;781:71-87. Epub 2019 Mar 6.

Department of Pharmacology & Toxicology, School for Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, The Netherlands.

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http://dx.doi.org/10.1016/j.mrrev.2019.03.002DOI Listing
March 2019

Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review.

Phytomedicine 2018 Sep 8;48:84-93. Epub 2018 May 8.

Team of Histomorphology, Physiopathology and Applied Toxicology, CIIMAR - Interdisciplinary Center for Marine and Environmental Research, U.Porto - University of Porto, Avenida General Norton de Matos s/n, Matosinhos 4450-208, Portugal; Laboratory of Histology and Embryology, Department of Microscopy, ICBAS - Institute of Biomedical Sciences Abel Salazar, U.Porto - University of Porto, Rua de Jorge Viterbo Ferreira, n° 228, Porto 4050-313, Portugal.

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https://linkinghub.elsevier.com/retrieve/pii/S09447113183014
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http://dx.doi.org/10.1016/j.phymed.2018.04.062DOI Listing
September 2018

Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi.

J Med Chem 2018 07 22;61(13):5643-5663. Epub 2018 Jun 22.

Departament of Parasitology , Instituto de Investigación Biosanitaria (ibs.Granada), Hospitales Universitarios De Granada/University of Granada , Severo Ochoa s/n , E-18071 Granada , Spain.

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http://dx.doi.org/10.1021/acs.jmedchem.8b00468DOI Listing
July 2018

Is oxidative stress involved in the sex-dependent response to ochratoxin A renal toxicity?

Food Chem Toxicol 2018 Jun 22;116(Pt B):379-387. Epub 2018 Apr 22.

University of Navarra, Department of Pharmacology and Toxicology, Faculty of Pharmacy and Nutrition, c/Irunlarrea 1, 31008 Pamplona, Spain; IdiSNA, Navarra Institute for Health Research, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2018.04.050DOI Listing
June 2018

The comet assay applied to cells of the eye.

Mutagenesis 2018 02;33(1):21-24

Department of Nutrition, Institute for Basic Medical Sciences, University of Oslo, Sognsvannsveien, Oslo, Norway.

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http://dx.doi.org/10.1093/mutage/gex025DOI Listing
February 2018

Standardisation of the in vitro comet assay: influence of lysis time and lysis solution composition on the detection of DNA damage induced by X-rays.

Mutagenesis 2018 02;33(1):25-30

Department of Pharmacology and Toxicology, University of Navarra, and IdiSNA, Navarra Institute for Health Research, Pamplona, Spain.

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http://dx.doi.org/10.1093/mutage/gex039DOI Listing
February 2018

The next three decades of the comet assay: a report of the 11th International Comet Assay Workshop.

Mutagenesis 2017 05;32(3):397-408

Environmental Risk and Health unit, Flemish Institute of Technological Research (VITO), Boeretang 200, 2400 Mol, Belgium.

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http://dx.doi.org/10.1093/mutage/gex002DOI Listing
May 2017

Polyphenols and DNA Damage: A Mixed Blessing.

Nutrients 2016 Dec 3;8(12). Epub 2016 Dec 3.

Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, PB 1046 Blindern, 0316 Oslo, Norway.

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http://dx.doi.org/10.3390/nu8120785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5188440PMC
December 2016

Preliminary study of genotoxicity evaluation of orthodontic miniscrews on mucosa oral cells by the alkaline comet assay.

Toxicol Mech Methods 2015 10;25(6):487-93. Epub 2015 Jun 10.

b Area of Toxicology, Faculty of Pharmacy, University of Sevilla , Sevilla , Spain .

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http://dx.doi.org/10.3109/15376516.2015.1053652DOI Listing
July 2016

Synthesis and biological evaluation of quinoxaline di-N-oxide derivatives with in vitro trypanocidal activity.

Bioorg Med Chem Lett 2016 Feb 21;26(3):903-906. Epub 2015 Dec 21.

Department of Organic and Pharmaceutical Chemistry, University of Navarra, Irunlarrea s/n, 31008 Pamplona, Spain; Institute of Tropical Health, University of Navarra, Irunlarrea s/n, 31008 Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2015.12.070DOI Listing
February 2016

The comet assay: past, present, and future.

Front Genet 2015 13;6:266. Epub 2015 Aug 13.

Department of Nutrition, University of Oslo Oslo, Norway.

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http://dx.doi.org/10.3389/fgene.2015.00266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534839PMC
August 2015

The use of the comet assay for the evaluation of the genotoxicity of nanomaterials.

Front Genet 2015 10;6:239. Epub 2015 Jul 10.

Health Effects Laboratory, Department of Environmental Chemistry, NILU-Norwegian Institute for Air Research Kjeller, Norway.

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http://dx.doi.org/10.3389/fgene.2015.00239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498100PMC
July 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

Genotoxicity of Aflatoxin B1 and Ochratoxin A after simultaneous application of the in vivo micronucleus and comet assay.

Food Chem Toxicol 2015 Feb 18;76:116-24. Epub 2014 Dec 18.

Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2014.12.003DOI Listing
February 2015

Does the duration of lysis affect the sensitivity of the in vitro alkaline comet assay?

Mutagenesis 2015 Jan;30(1):21-8

Department of Pharmacology and Toxicology, University of Navarra, Irunlarrea 1, 31009 Pamplona, Spain

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http://dx.doi.org/10.1093/mutage/geu047DOI Listing
January 2015

Critical factors to be considered when testing nanomaterials for genotoxicity with the comet assay.

Mutagenesis 2015 Jan;30(1):85-8

Health Effects Laboratory, Department of Environmental Chemistry, NILU-Norwegian Institute for Air Research, Instituttveien 18, 2007 Kjeller, Norway,

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http://dx.doi.org/10.1093/mutage/geu077DOI Listing
January 2015

Assessment of DNA damage using comet assay in middle-aged overweight/obese subjects after following a hypocaloric diet supplemented with cocoa extract.

Mutagenesis 2015 Jan;30(1):139-46

Department of Nutrition, Food Science and Physiology, Nutrition Research Centre, University of Navarra, C/Irunlarrea 1, 31008 Pamplona, Navarra, Spain, Physiopathology of Obesity and Nutrition, CIBERobn, Carlos III Health Research Institute, 28029 Madrid, Spain.

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https://academic.oup.com/mutage/article-lookup/doi/10.1093/m
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http://dx.doi.org/10.1093/mutage/geu056DOI Listing
January 2015

Controlling variation in the comet assay.

Front Genet 2014 20;5:359. Epub 2014 Oct 20.

Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Navarra Pamplona, Spain.

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http://dx.doi.org/10.3389/fgene.2014.00359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202776PMC
November 2014

High throughput sample processing and automated scoring.

Front Genet 2014 28;5:373. Epub 2014 Oct 28.

Department of Chemicals and Radiation, Division of Environmental Medicine, Norwegian Institute of Public Health Oslo, Norway.

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http://dx.doi.org/10.3389/fgene.2014.00373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211552PMC
November 2014

Comet assay to measure DNA repair: approach and applications.

Front Genet 2014 25;5:288. Epub 2014 Aug 25.

Department of Nutrition, University of Oslo Oslo, Norway.

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http://dx.doi.org/10.3389/fgene.2014.00288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142706PMC
September 2014

Base excision repair capacity in chronic renal failure patients undergoing hemodialysis treatment.

Cell Biochem Funct 2014 Mar 19;32(2):177-82. Epub 2013 Jul 19.

Grup de Mutagènesi, Departament de Genètica i de Microbiologia, Edifici Cn, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/cbf.2989DOI Listing
March 2014

Measurement of DNA base and nucleotide excision repair activities in mammalian cells and tissues using the comet assay--a methodological overview.

DNA Repair (Amst) 2013 Nov 17;12(11):1007-10. Epub 2013 Sep 17.

Department of Pharmacology and Toxicology, University of Navarra, C/Irunlarrea 1, 31009 Pamplona, Spain; Department of Nutrition, University of Oslo, PB 1046 Blindern, Oslo, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2013.07.011DOI Listing
November 2013

The comet assay, DNA damage, DNA repair and cytotoxicity: hedgehogs are not always dead.

Mutagenesis 2013 Jul 29;28(4):427-32. Epub 2013 Apr 29.

Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1093/mutage/get018DOI Listing
July 2013

The essential comet assay: a comprehensive guide to measuring DNA damage and repair.

Arch Toxicol 2013 Jun 18;87(6):949-68. Epub 2013 May 18.

Department of Pharmacology and Toxicology, University of Navarra, C/Irunlarrea 1, 31009 Pamplona, Spain.

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http://link.springer.com/content/pdf/10.1007%2Fs00204-013-10
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http://link.springer.com/10.1007/s00204-013-1070-0
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http://dx.doi.org/10.1007/s00204-013-1070-0DOI Listing
June 2013

Enhancing the sensitivity of the comet assay as a genotoxicity test, by combining it with bacterial repair enzyme FPG.

Mutagenesis 2013 May 28;28(3):271-7. Epub 2013 Feb 28.

Department of Nutrition, Food Science, Physiology and Toxicology, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1093/mutage/get002DOI Listing
May 2013

Vitamin C in cultured human (HeLa) cells: lack of effect on DNA protection and repair.

Nutrients 2013 Apr 9;5(4):1200-17. Epub 2013 Apr 9.

Department of Pharmacology and Toxicology, University of Navarra, C/Irunlarrea 1, 31008 Pamplona, Spain.

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http://dx.doi.org/10.3390/nu5041200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705343PMC
April 2013

A comparative performance test of standard, medium- and high-throughput comet assays.

Toxicol In Vitro 2013 Mar 20;27(2):768-73. Epub 2012 Dec 20.

Department of Nutrition, Faculty of Medicine, University of Oslo, P.O. Box 1046, Blindern, 0316 Oslo, Norway.

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http://dx.doi.org/10.1016/j.tiv.2012.12.006DOI Listing
March 2013

DNA repair as a biomarker in human biomonitoring studies; further applications of the comet assay.

Mutat Res 2012 Aug 1;736(1-2):122-9. Epub 2011 Apr 1.

Department of Nutrition, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1016/j.mrfmmm.2011.03.005DOI Listing
August 2012

Carotenoids and DNA damage.

Mutat Res 2012 May 21;733(1-2):4-13. Epub 2012 Mar 21.

Department of Nutrition, Food Science and Toxicology, Schools of Pharmacy and Sciences, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain.

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http://dx.doi.org/10.1016/j.mrfmmm.2012.03.005DOI Listing
May 2012

Effects of micronutrients on DNA repair.

Eur J Nutr 2012 Apr 24;51(3):261-79. Epub 2012 Feb 24.

Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Blindern, PB 1046, 0316, Oslo, Norway.

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http://link.springer.com/10.1007/s00394-012-0318-4
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http://dx.doi.org/10.1007/s00394-012-0318-4DOI Listing
April 2012

Towards a more reliable comet assay: optimising agarose concentration, unwinding time and electrophoresis conditions.

Mutat Res 2011 Sep 30;724(1-2):41-5. Epub 2011 May 30.

Department of Nutrition, Faculty of Medicine, University of Oslo, PB 1046 Blindern, 0316 Oslo, Norway.

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https://linkinghub.elsevier.com/retrieve/pii/S13835718110016
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http://dx.doi.org/10.1016/j.mrgentox.2011.05.010DOI Listing
September 2011

The influence of scoring method on variability in results obtained with the comet assay.

Mutagenesis 2011 May 11;26(3):393-9. Epub 2011 Jan 11.

Department of Nutrition, Faculty of Medicine, University of Oslo, PO Box 1046 Blindern, 0316 Oslo, Norway.

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http://dx.doi.org/10.1093/mutage/geq105DOI Listing
May 2011

Both base excision repair and nucleotide excision repair in humans are influenced by nutritional factors.

Cell Biochem Funct 2011 Jan-Feb;29(1):36-42. Epub 2010 Dec 20.

Division of Environmental Medicine, Department of Chemical Toxicology, Norwegian Institute of Public Health, Oslo, Norway.

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http://dx.doi.org/10.1002/cbf.1715DOI Listing
May 2011

Polyphenolic compounds from Salvia species protect cellular DNA from oxidation and stimulate DNA repair in cultured human cells.

J Agric Food Chem 2010 Jun;58(12):7465-71

Department of Nutrition, University of Oslo, Oslo, Norway.

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http://dx.doi.org/10.1021/jf100082pDOI Listing
June 2010

Effect of processed and red meat on endogenous nitrosation and DNA damage.

Carcinogenesis 2009 Aug 4;30(8):1402-7. Epub 2009 Jun 4.

MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1093/carcin/bgp130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718076PMC
August 2009

In vitro comet assay for DNA repair: a warning concerning application to cultured cells.

Mutagenesis 2009 Jul 2;24(4):379-81. Epub 2009 Apr 2.

Department of Nutrition, University of Oslo, Norway.

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http://dx.doi.org/10.1093/mutage/gep009DOI Listing
July 2009

DNA oxidation: investigating its key role in environmental mutagenesis with the comet assay.

Mutat Res 2009 Mar 11;674(1-2):101-8. Epub 2008 Nov 11.

Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, PB 1046 Blindern, 0316 Oslo, Norway.

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http://dx.doi.org/10.1016/j.mrgentox.2008.10.013DOI Listing
March 2009

Novel Cu(II) quinoxaline N1,N4-dioxide complexes as selective hypoxic cytotoxins.

Eur J Med Chem 2005 May;40(5):473-80

Cátedra de Química Inorgánica, Facultad de Química, Universidad de la República, Gral. Flores 2124, 11200 Montevideo, Uruguay.

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http://dx.doi.org/10.1016/j.ejmech.2004.11.012DOI Listing
May 2005