Amato Giaccia

Amato Giaccia

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Amato Giaccia

Publications by authors named "Amato Giaccia"

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Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma.

Innate Immun 2020 02 23;26(2):130-137. Epub 2019 Sep 23.

Division of Pediatric Neurosurgery, Department of Neurosurgery, Lucile Packard Children's Hospital, Stanford University School of Medicine, USA.

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http://dx.doi.org/10.1177/1753425919876690DOI Listing
February 2020

HILPDA Regulates Lipid Metabolism, Lipid Droplet Abundance, and Response to Microenvironmental Stress in Solid Tumors.

Mol Cancer Res 2019 Oct 15;17(10):2089-2101. Epub 2019 Jul 15.

Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-1343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774878PMC
October 2019

Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition.

Cancers (Basel) 2019 Aug 16;11(8). Epub 2019 Aug 16.

Global Station for Quantum Medical Science and Engineering, Global Institution for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Hokkaido 060-8638, Japan.

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http://dx.doi.org/10.3390/cancers11081192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721563PMC
August 2019

Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate.

Dev Cell 2019 06 16;49(5):748-763.e7. Epub 2019 May 16.

Departments of Orthopaedic Surgery, Medicine, and Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.04.029DOI Listing
June 2019

Targeting the Tumor Microenvironment in Radiation Oncology: Proceedings from the 2018 ASTRO-AACR Research Workshop.

Clin Cancer Res 2019 05 5;25(10):2969-2974. Epub 2019 Feb 5.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3781DOI Listing
May 2019

Wounds Inhibit Tumor Growth In Vivo.

Ann Surg 2019 Feb 27. Epub 2019 Feb 27.

Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA.

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http://dx.doi.org/10.1097/SLA.0000000000003255DOI Listing
February 2019

Generation of Stable Expression Mammalian Cell Lines Using Lentivirus.

Bio Protoc 2018 Nov;8(21)

Department of Radiation Oncology, Stanford University, Stanford, CA, USA.

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https://bio-protocol.org/e3073
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http://dx.doi.org/10.21769/BioProtoc.3073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261361PMC
November 2018

The tumour microenvironment links complement system dysregulation and hypoxic signalling.

Br J Radiol 2018 May 15:20180069. Epub 2018 May 15.

1 Department of Radiation Oncology, Stanford University , Stanford, CA , USA.

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http://dx.doi.org/10.1259/bjr.20180069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435069PMC
May 2018

Selection of external beam radiotherapy approaches for precise and accurate cancer treatment.

J Radiat Res 2018 Mar;59(suppl_1):i2-i10

Global Station for Quantum Medical Science and Engineering, Global Institute for Cooperative Research and Education, Hokkaido University, North-15 West-7, Kita-ku, 0608638, Sapporo, Hokkaido, Japan.

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http://dx.doi.org/10.1093/jrr/rrx092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868193PMC
March 2018

PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing.

Plast Reconstr Surg 2018 01;141(1):55e-67e

Stanford, San Diego, and San Francisco, Calif.; Portland, Ore.; and New York, N.Y. From the Hagey Laboratory for Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, the Department of Radiation Oncology, and the Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine; the Division of Vascular Surgery, Department of Surgery, University of California, San Diego; the Division of Plastic and Reconstructive Surgery, Department of Surgery, Oregon Health and Sciences University; the Division of Cardiothoracic Surgery, Department of Surgery, New York Presbyterian Hospital; and the Department of Radiation Oncology, University of California, San Francisco.

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http://dx.doi.org/10.1097/PRS.0000000000003959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747314PMC
January 2018

Metabolic Alterations in Cancer and Their Potential as Therapeutic Targets.

Am Soc Clin Oncol Educ Book 2017 ;37:825-832

From the Department of Medicine, Division of Hematology and Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA.

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http://dx.doi.org/10.1200/EDBK_175561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954416PMC
November 2017

Long-range hypoxia signaling in NAFLD.

Nat Med 2017 11;23(11):1251-1252

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, California, USA.

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http://www.nature.com/articles/nm.4436
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http://dx.doi.org/10.1038/nm.4436DOI Listing
November 2017

Hypoxia and Bone Metastatic Disease.

Curr Osteoporos Rep 2017 08;15(4):231-238

Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1007/s11914-017-0378-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667665PMC
August 2017

Lorenz Poellinger.

Exp Cell Res 2017 07;356(2):115

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http://dx.doi.org/10.1016/j.yexcr.2017.05.026DOI Listing
July 2017

Isolation of Proteins on Nascent DNA in Hypoxia and Reoxygenation Conditions.

Adv Exp Med Biol 2016 ;899:27-40

CR-UK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1007/978-3-319-26666-4_3DOI Listing
June 2017

Measuring the Impact of Microenvironmental Conditions on Mitochondrial Dehydrogenase Activity in Cultured Cells.

Adv Exp Med Biol 2016;899:113-20

Department of Radiation Oncology, Ohio State University Wexner School of Medicine and Comprehensive Cancer Center, Ohio Sate University, Columbus, OH, 43210, USA.

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http://link.springer.com/10.1007/978-3-319-26666-4_7
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http://dx.doi.org/10.1007/978-3-319-26666-4_7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017243PMC
June 2017

Molecular Pathways: Oncologic Pathways and Their Role in T-cell Exclusion and Immune Evasion-A New Role for the AXL Receptor Tyrosine Kinase.

Clin Cancer Res 2017 Jun 13;23(12):2928-2933. Epub 2017 Mar 13.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474155PMC
June 2017

Pre-metastatic niches: organ-specific homes for metastases.

Nat Rev Cancer 2017 05 17;17(5):302-317. Epub 2017 Mar 17.

Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics, and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medicine, New York, New York 10021, USA.

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http://dx.doi.org/10.1038/nrc.2017.6DOI Listing
May 2017

Patterns of Vasculature in Mouse Models of Lung Cancer Are Dependent on Location.

Mol Imaging Biol 2017 04;19(2):215-224

Department of Radiation Oncology, Molecular Imaging Program at Stanford and Bio-X Program, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1007/s11307-016-1010-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546406PMC
April 2017

KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage.

Nucleic Acids Res 2017 04;45(7):3674-3692

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1093/nar/gkw1281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397198PMC
April 2017

A New Chromatin-Cytoskeleton Link in Cancer.

Authors:
Amato J Giaccia

Mol Cancer Res 2016 12 15;14(12):1173-1175. Epub 2016 Aug 15.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University Medical Center, Stanford, California.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136307PMC
December 2016

Reprogramming the immunological microenvironment through radiation and targeting Axl.

Nat Commun 2016 12 23;7:13898. Epub 2016 Dec 23.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, 269 Campus Drive, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ncomms13898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5196438PMC
December 2016

Telomere shortening and metabolic compromise underlie dystrophic cardiomyopathy.

Proc Natl Acad Sci U S A 2016 11 31;113(46):13120-13125. Epub 2016 Oct 31.

Baxter Laboratory for Stem Cell Biology, Stanford University School of Medicine, Stanford University, Stanford, CA 94305;

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http://dx.doi.org/10.1073/pnas.1615340113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135315PMC
November 2016

The Receptor Tyrosine Kinase AXL in Cancer Progression.

Cancers (Basel) 2016 Nov 9;8(11). Epub 2016 Nov 9.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305, USA.

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http://dx.doi.org/10.3390/cancers8110103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5126763PMC
November 2016

Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow.

Nat Cell Biol 2016 10 19;18(10):1078-1089. Epub 2016 Sep 19.

Department of Radiation Oncology, Division of Radiation and Cancer Biology, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ncb3408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357601PMC
October 2016

Hypoxia: Signaling the Metastatic Cascade.

Trends Cancer 2016 06 2;2(6):295-304. Epub 2016 Jun 2.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305-5152, USA. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2016.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808868PMC
June 2016

The ever-expanding role of HIF in tumour and stromal biology.

Nat Cell Biol 2016 Apr;18(4):356-65

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1038/ncb3330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898054PMC
April 2016

Hypoxic control of metastasis.

Science 2016 Apr 7;352(6282):175-80. Epub 2016 Apr 7.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA 94305-5152, USA.

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http://dx.doi.org/10.1126/science.aaf4405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4898055PMC
April 2016

Mechanisms and consequences of ATMIN repression in hypoxic conditions: roles for p53 and HIF-1.

Sci Rep 2016 Feb 15;6:21698. Epub 2016 Feb 15.

Cancer Research UK and Medical Research Council Oxford Institute for Radiation Oncology, Department of Oncology, The University of Oxford, Oxford, OX3 7DQ, UK.

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http://dx.doi.org/10.1038/srep21698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753685PMC
February 2016

Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors.

Am J Pathol 2015 Nov 6;185(11):3090-101. Epub 2015 Sep 6.

Department of Orthopaedic Surgery and the Division of Endocrinology, Department of Medicine, University of Michigan Medical School, Ann Arbor, Michigan; Division of Endocrinology, Department of Medicine, Indiana University, Indianapolis, Indiana; Endocrine Unit, Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2015.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801489PMC
November 2015

Risk of breast cancer among patients with bioprosthetic or mechanical valve replacement: a population-based study in Sweden.

Breast Cancer Res Treat 2015 Nov 17;154(2):369-75. Epub 2015 Oct 17.

Center for Primary Health Care Research, CRC, Lund University/Region Skåne, Skåne University Hospital, Building 28, Floor 11, Jan Waldenströms gata 35, 205 02, Malmö, Sweden.

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http://link.springer.com/content/pdf/10.1007/s10549-015-3607
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http://link.springer.com/10.1007/s10549-015-3607-9
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http://dx.doi.org/10.1007/s10549-015-3607-9DOI Listing
November 2015

Emerging Treatment Paradigms in Radiation Oncology.

Clin Cancer Res 2015 Aug 19;21(15):3393-401. Epub 2015 May 19.

Department of Radiation Oncology, Stanford University, Stanford, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526434PMC
August 2015

Loss of HIF-1α in the notochord results in cell death and complete disappearance of the nucleus pulposus.

PLoS One 2014 22;9(10):e110768. Epub 2014 Oct 22.

Department of Orthopaedic Surgery and Graduate Program in Cell and Developmental Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206488PMC
July 2015

Gastrointestinal Toxicities With Combined Antiangiogenic and Stereotactic Body Radiation Therapy.

Int J Radiat Oncol Biol Phys 2015 Jul;92(3):568-76

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.02.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816453PMC
July 2015

Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma.

Cell Rep 2015 Jul 25;12(1):116-127. Epub 2015 Jun 25.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.06.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518559PMC
July 2015

HIF targets in bone remodeling and metastatic disease.

Pharmacol Ther 2015 Jun 12;150:169-77. Epub 2015 Feb 12.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2015.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414805PMC
June 2015

The end of the hypoxic EPOch.

Int J Radiat Oncol Biol Phys 2015 Apr;91(5):895-7

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.01.041DOI Listing
April 2015

Dual roles of NRF2 in tumor prevention and progression: possible implications in cancer treatment.

Free Radic Biol Med 2015 Feb 29;79:292-9. Epub 2014 Nov 29.

Division of Radiation Biology & Oncology, Department of Radiation Oncology, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339613PMC
February 2015

Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.

Cell Rep 2015 Feb 19;10(7):1096-109. Epub 2015 Feb 19.

Department of Radiation Oncology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4365998PMC
February 2015

Epidermal or dermal specific knockout of PHD-2 enhances wound healing and minimizes ischemic injury.

PLoS One 2014 2;9(4):e93373. Epub 2014 Apr 2.

Hagey Laboratory for Pediatric Regenerative Medicine, Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, California, United States of America; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093373PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973687PMC
January 2015

Osteoblasts: a novel source of erythropoietin.

Curr Osteoporos Rep 2014 Dec;12(4):428-32

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford University, Stanford, CA, 94303-5152, USA.

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http://dx.doi.org/10.1007/s11914-014-0236-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349388PMC
December 2014

An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis.

Nat Chem Biol 2014 Nov 21;10(11):977-83. Epub 2014 Sep 21.

1] Department of Bioengineering, Stanford University, Stanford, California, USA. [2] Department of Chemical Engineering, Stanford University, Stanford, California, USA.

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http://dx.doi.org/10.1038/nchembio.1636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372605PMC
November 2014

Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development.

Dev Biol 2014 Sep 24;393(1):124-36. Epub 2014 Jun 24.

Department of Orthopaedic Surgery, Medical School, University of Michigan, Ann Arbor, MI 48109, USA; Division of Endocrinology, Department of Medicine, School of Medicine, Indiana University, Indianapolis, IN 46202, USA; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Division of Endocrinology, Department of Medicine, Medical School, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2014.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335807PMC
September 2014

Molecular radiobiology: the state of the art.

Authors:
Amato J Giaccia

J Clin Oncol 2014 Sep 11;32(26):2871-8. Epub 2014 Aug 11.

Stanford University School of Medicine, Stanford, CA.

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http://dx.doi.org/10.1200/JCO.2014.57.2776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152715PMC
September 2014

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

Proc Natl Acad Sci U S A 2014 Sep 3;111(37):13373-8. Epub 2014 Sep 3.

Division of Radiation and Cancer Biology and Center for Clinical Sciences Research, Department of Radiation Oncology, Stanford University, Stanford, CA, 94305;

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http://dx.doi.org/10.1073/pnas.1404848111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169907PMC
September 2014

Recruitment of circulating breast cancer cells is stimulated by radiotherapy.

Cell Rep 2014 Jul 10;8(2):402-9. Epub 2014 Jul 10.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305, USA; Division of Radiation Physics, Department of Radiation Oncology, Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121080PMC
July 2014

Identifying novel targets in renal cell carcinoma: design and synthesis of affinity chromatography reagents.

Bioorg Med Chem 2014 Jan 20;22(2):711-20. Epub 2013 Dec 20.

Auckland Cancer Society Research Centre, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2013.12.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713883PMC
January 2014

HIF-2: the missing link between obesity and cardiomyopathy.

Authors:
Amato J Giaccia

J Am Heart Assoc 2013 Dec 16;2(6):e000710. Epub 2013 Dec 16.

Department of Radiation Oncology, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1161/JAHA.113.000710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886772PMC
December 2013

Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes.

Nat Med 2013 Oct 15;19(10):1325-30. Epub 2013 Sep 15.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford, California, USA.

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http://dx.doi.org/10.1038/nm.3294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089950PMC
October 2013

Regulation of Bone Marrow Angiogenesis by Osteoblasts during Bone Development and Homeostasis.

Front Endocrinol (Lausanne) 2013 10;4:85. Epub 2013 Jul 10.

Division of Endocrinology, Department of Medicine, Indiana University Medical School , Indianapolis, IN , USA.

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http://dx.doi.org/10.3389/fendo.2013.00085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706978PMC
July 2013

A low-carb diet kills tumor cells with a mutant p53 tumor suppressor gene: the Atkins diet suppresses tumor growth.

Cell Cycle 2013 Mar 19;12(5):718-9. Epub 2013 Feb 19.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.4161/cc.23948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3610718PMC
March 2013

The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.

Cell 2012 Mar;149(1):63-74

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford University, Stanford, CA 94303-5152, USA.

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http://dx.doi.org/10.1016/j.cell.2012.01.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408231PMC
March 2012

Tumor galectin-1 mediates tumor growth and metastasis through regulation of T-cell apoptosis.

Cancer Res 2011 Jul 5;71(13):4423-31. Epub 2011 May 5.

Department of Radiation Oncology, Stanford University, Stanford, California 94305, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129397PMC
July 2011

A central role for hypoxic signaling in cartilage, bone, and hematopoiesis.

Curr Osteoporos Rep 2011 Jun;9(2):46-52

Endocrine Unit, Massachusetts General Hospital-Harvard Medical School, Boston, MA 02114, USA.

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http://link.springer.com/10.1007/s11914-011-0047-2
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http://dx.doi.org/10.1007/s11914-011-0047-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4012534PMC
June 2011

Hypoxia and senescence: the impact of oxygenation on tumor suppression.

Mol Cancer Res 2011 May 8;9(5):538-44. Epub 2011 Mar 8.

Department of Radiation Oncology, School of Medicine, Case Western Reserve University, 10900 Euclid Avenue, BRB 325, Cleveland, OH 44106, USA.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-11
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http://dx.doi.org/10.1158/1541-7786.MCR-11-0065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3096743PMC
May 2011

Harnessing synthetic lethal interactions in anticancer drug discovery.

Nat Rev Drug Discov 2011 May;10(5):351-64

Department of Radiation Oncology, University of California, San Francisco, California 94143-1331, USA.

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http://dx.doi.org/10.1038/nrd3374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652585PMC
May 2011

VHL loss in renal cell carcinoma leads to up-regulation of CUB domain-containing protein 1 to stimulate PKC{delta}-driven migration.

Proc Natl Acad Sci U S A 2011 Feb 13;108(5):1931-6. Epub 2011 Jan 13.

Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1073/pnas.1011777108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033256PMC
February 2011

Control of lysyl oxidase activity through site-specific deuteration of lysine.

Bioorg Med Chem Lett 2011 Jan 5;21(1):255-8. Epub 2010 Nov 5.

Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow 117871, Russia.

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http://dx.doi.org/10.1016/j.bmcl.2010.11.018DOI Listing
January 2011

Renal oxygenation suppresses VHL loss-induced senescence that is caused by increased sensitivity to oxidative stress.

Mol Cell Biol 2010 Oct 2;30(19):4595-603. Epub 2010 Aug 2.

Department of Radiation Oncology, Stanford University School of Medicine, 1235 CCSR, 269 Campus Drive, Stanford, CA 93025, USA.

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http://dx.doi.org/10.1128/MCB.01618-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950534PMC
October 2010

AXL is an essential factor and therapeutic target for metastatic ovarian cancer.

Cancer Res 2010 Oct 21;70(19):7570-9. Epub 2010 Sep 21.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, Center for Clinical Sciences Research, Stanford University, Stanford, California 94305-5152, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-1267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408227PMC
October 2010

Hypoxia in models of lung cancer: implications for targeted therapeutics.

Clin Cancer Res 2010 Oct 21;16(19):4843-52. Epub 2010 Sep 21.

Department of Radiation Oncology, Stanford University, California 94305-5847, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-1206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948600PMC
October 2010