Publications by authors named "Amanda Swain"

52Publications

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis.

Cell 2020 Aug 14;182(4):901-918.e18. Epub 2020 Jul 14.

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Andrew M. and Jane M. Bursky Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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August 2020

Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.

Cell Metab 2020 02;31(2):250-266.e9

Goodman Cancer Research Centre, McGill University, Montreal, QC H3A 1A3, Canada; Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada; Metabolic and Nutritional Programming, Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI 49503, USA. Electronic address:

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February 2020

The Fostering Resilience through Art in Medical Education (FRAME) workshop: a partnership with the Philadelphia Museum of Art.

Adv Med Educ Pract 2019 27;10:361-369. Epub 2019 May 27.

Academic Programs Office, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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May 2019

Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures.

Nat Commun 2019 05 17;10(1):2209. Epub 2019 May 17.

Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, 63110, USA.

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May 2019

Prostate Organogenesis.

Cold Spring Harb Perspect Med 2018 07 2;8(7). Epub 2018 Jul 2.

Division of Cancer Biology, Institute of Cancer Research, London SW3 6JB, United Kingdom.

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July 2018

Ductal sex determination.

Authors:
Amanda Swain

Science 2017 08;357(6352):648

Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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August 2017

Polycomb repressive complex 1 modifies transcription of active genes.

Sci Adv 2017 08 2;3(8):e1700944. Epub 2017 Aug 2.

Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.

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August 2017

Drosophila TDP-43 RNA-Binding Protein Facilitates Association of Sister Chromatid Cohesion Proteins with Genes, Enhancers and Polycomb Response Elements.

PLoS Genet 2016 Sep 23;12(9):e1006331. Epub 2016 Sep 23.

Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, Missouri, United States of America.

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September 2016

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer.

N Engl J Med 2015 Oct;373(18):1697-708

From the Institute of Cancer Research (J.M., S.C., S.S., S.M., H.M., R.P.-L., D.N.R., A.O., N.T., G.B., N.P., P.F., A.G., I.F., C.P., G.S., D.B., J.G., Z.Z., C.T.W., R.F., R.R., B.E., G.F., D. Roda, W.Y., R.B., H.P., R.A., A.S., R.E., G.A., C.J.L., A.A., E.H., J.S.B.), the Royal Marsden NHS Foundation Trust (J.M., S.S., R.P.-L., A.O., N.T., D.B., Z.Z., R.F., D. Roda, R.E., G.A., J.S.B.), and University College London Hospital (U.M.), London, Queen's University, Belfast (S.J.), University of Leeds, Leeds (C.R.), Churchill Hospital, Oxford (A.P.), University of Liverpool, Liverpool (S.H.), Beatson West of Scotland Cancer Centre, Glasgow (R.J.), and Christie Hospital, Manchester (T.E.) - all in the United Kingdom; the University of Michigan, Ann Arbor (D. Robinson, Y.-M.W., X.C., L.P.K., F.Y.F., A.M.C.); Weill Cornell Medical College, New York (M.A.R.); and Thomas Jefferson University, Philadelphia (K.E.K.).

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October 2015

Pten Regulates Epithelial Cytodifferentiation during Prostate Development.

PLoS One 2015 15;10(6):e0129470. Epub 2015 Jun 15.

Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London, United Kingdom.

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April 2016

Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development.

Dev Biol 2014 Nov 27;395(2):209-17. Epub 2014 Sep 27.

Division of Cancer Biology, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, United Kingdom. Electronic address:

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November 2014

β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.

PLoS Genet 2013 3;9(1):e1003180. Epub 2013 Jan 3.

Division of Cancer Biology, Institute of Cancer Research, London, United Kingdom.

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May 2013

In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland.

Development 2012 Dec 7;139(24):4561-70. Epub 2012 Nov 7.

Division of Cancer Biology, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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December 2012

SF-1 expression during adrenal development and tumourigenesis.

Mol Cell Endocrinol 2012 Mar 15;351(1):12-8. Epub 2011 Oct 15.

Division of Cancer Biology, Institute of Cancer Research, London SW36JB, UK.

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March 2012

Wnt4/β-catenin signaling induces VSMC proliferation and is associated with intimal thickening.

Circ Res 2011 Feb 30;108(4):427-36. Epub 2010 Dec 30.

Bristol Heart Institute, University of Bristol, Bristol Royal Infirmary, Bristol, United Kingdom.

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February 2011

Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis.

PLoS Genet 2010 Jun 24;6(6):e1000995. Epub 2010 Jun 24.

Section of Gene Function and Regulation, Institute of Cancer Research, London, United Kingdom.

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June 2010

Gene dosage effects and transcriptional regulation of early mammalian adrenal cortex development.

Mol Cell Endocrinol 2010 Jul 16;323(1):105-14. Epub 2009 Dec 16.

Centre National de la Recherche Scientifique, Unité mixte de Recherche 6247, Génétique, Reproduction et Développement, Clermont Université, 63177 Aubière, France.

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July 2010

The transcription co-factor CITED2 functions during sex determination and early gonad development.

Hum Mol Genet 2009 Aug 20;18(16):2989-3001. Epub 2009 May 20.

Section of Gene Function and Regulation, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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August 2009

The role of Sox9 in prostate development.

Differentiation 2008 Jul 28;76(6):728-35. Epub 2008 Jun 28.

Section of Gene Function and Regulation, Institute of Cancer Research, 237 Fulham Road, London SW36JB, UK.

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July 2008

Sox9 is required for prostate development.

Dev Biol 2008 Apr 7;316(2):302-11. Epub 2008 Feb 7.

Section of Gene Function and Regulation, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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April 2008

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage.

Development 2007 Jun;134(12):2349-58

Section of Gene Function and Regulation, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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June 2007

Identification of a novel population of adrenal-like cells in the mammalian testis.

Dev Biol 2006 Nov 31;299(1):250-6. Epub 2006 Jul 31.

Section of Gene Function and Regulation, Institute of Cancer Research, London SW3 6JB, UK.

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November 2006

Sex determination: time for meiosis? The gonad decides.

Authors:
Amanda Swain

Curr Biol 2006 Jul;16(13):R507-9

Section of Gene Function and Regulation, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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July 2006

Mechanisms of Disease: normal and abnormal gonadal development and sex determination in mammals.

Nat Clin Pract Urol 2005 Dec;2(12):616-27

Institute of Cancer Research, London, UK.

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December 2005

Wnt4 is required for proper male as well as female sexual development.

Dev Biol 2004 Dec;276(2):431-40

Section of Gene Function and Regulation, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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December 2004

Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis.

Dev Dyn 2004 Jun;230(2):210-5

Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, USA.

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June 2004

Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad.

Development 2003 Aug;130(16):3663-70

Section of Gene Function and Regulation, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK.

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August 2003

Vertebrate sex determination: a new player in the field.

Authors:
Amanda Swain

Curr Biol 2002 Sep;12(17):R602-3

Section of Gene Function and Regulation, Chester Beatty Laboratories, Institute of Cancer Research, London SW3 6JB, UK.

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September 2002

Dax1 expression is dependent on steroidogenic factor 1 in the developing gonad.

Mol Endocrinol 2002 Apr;16(4):747-56

Section of Gene Function and Regulation, Chester Beatty Laboratories, Institute of Cancer Research, London SW3 6JB.

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April 2002