Amanda K Lukens

Amanda K Lukens

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Amanda K Lukens

Amanda K Lukens

Publications by authors named "Amanda K Lukens"

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28Publications

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The Adaptive Proline Response in P. falciparum Is Independent of PfeIK1 and eIF2α Signaling.

ACS Infect Dis 2019 Apr 21;5(4):515-520. Epub 2019 Feb 21.

Harvard T.H. Chan School of Public Health , 665 Huntington Avenue , Boston , Massachusetts 02115 , United States.

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http://dx.doi.org/10.1021/acsinfecdis.8b00363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747701PMC
April 2019

Identification of Collateral Sensitivity to Dihydroorotate Dehydrogenase Inhibitors in Plasmodium falciparum.

ACS Infect Dis 2018 04 22;4(4):508-515. Epub 2018 Jan 22.

Department of Immunology and Infectious Diseases , Harvard T. H. Chan School of Public Health , 665 Huntington Avenue , Boston , Massachusetts 02115 , United States.

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http://dx.doi.org/10.1021/acsinfecdis.7b00217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899019PMC
April 2018

Intramolecular Diaza-Diels-Alder Protocol: A New Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks.

Chemistry 2017 Mar 17;23(17):4137-4148. Epub 2017 Feb 17.

Sharjah Institute for Medical Research, University of Sharjah, P.O. Box 27272, Sharjah, UAE.

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http://dx.doi.org/10.1002/chem.201605231DOI Listing
March 2017

Genome-Wide Association Studies of Drug-Resistance Determinants.

Trends Parasitol 2017 03 27;33(3):214-230. Epub 2016 Oct 27.

The Broad Institute of MIT and Harvard, Infectious Disease Initiative, Cambridge, MA, USA; Harvard University, Organismic and Evolutionary Biology, Cambridge, MA, USA.

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http://dx.doi.org/10.1016/j.pt.2016.10.001DOI Listing
March 2017

Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes.

ACS Infect Dis 2016 11 7;2(11):816-826. Epub 2016 Apr 7.

Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health , Boston, Massachusetts 02115, United States.

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http://pubs.acs.org/doi/10.1021/acsinfecdis.6b00025
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http://dx.doi.org/10.1021/acsinfecdis.6b00025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109296PMC
November 2016

Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites.

ChemMedChem 2016 10 19;11(19):2194-2204. Epub 2016 Aug 19.

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003, Lisboa, Portugal.

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http://dx.doi.org/10.1002/cmdc.201600327DOI Listing
October 2016

Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype.

Eur J Med Chem 2015 Sep 31;102:320-33. Epub 2015 Jul 31.

Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Av. Professor Gama Pinto, 1640-003 Lisbon, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.07.047DOI Listing
September 2015

Clinical Sequencing Uncovers Origins and Evolution of Lassa Virus.

Cell 2015 Aug;162(4):738-50

FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; Broad Institute, Cambridge, MA 02142, USA; Department of Immunology and Infectious Disease, Harvard School of Public Health, Boston, MA 02115, USA. Electronic address:

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http://www.cell.com/cell/pdf/S0092-8674(15)00897-1.pdf
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http://linkinghub.elsevier.com/retrieve/pii/S009286741500897
Publisher Site
http://dx.doi.org/10.1016/j.cell.2015.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537774PMC
August 2015

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.

Sci Transl Med 2015 May;7(288):288ra77

Infectious Diseases Program, Broad Institute, Cambridge, MA 02142, USA. Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa3575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675670PMC
May 2015

Intrinsic susceptibility of mouse trophoblasts to natural killer cell-mediated attack in vivo.

Proc Natl Acad Sci U S A 2002 Dec 16;99(26):16940-5. Epub 2002 Dec 16.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.222652199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC139248PMC
December 2002