Amanda J Price

Amanda J Price

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Amanda J Price

Amanda J Price

Publications by authors named "Amanda J Price"

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21Publications

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Regional Heterogeneity in Gene Expression, Regulation, and Coherence in the Frontal Cortex and Hippocampus across Development and Schizophrenia.

Neuron 2019 07 4;103(2):203-216.e8. Epub 2019 Jun 4.

Lieber Institute for Brain Development, Johns Hopkins Medical Campus, Baltimore, MD 21205, USA; Center for Computational Biology, Johns Hopkins University, Baltimore, MD 21205, USA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2019.05.013DOI Listing
July 2019

Fragment-based drug discovery and its application to challenging drug targets.

Essays Biochem 2017 11 8;61(5):475-484. Epub 2017 Nov 8.

Astex Pharmaceuticals, 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, U.K.

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http://dx.doi.org/10.1042/EBC20170029DOI Listing
November 2017

The PsychENCODE project.

Nat Neurosci 2015 Dec;18(12):1707-12

Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nn.4156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4675669PMC
December 2015

Engineering targeted chromosomal amplifications in human breast epithelial cells.

Breast Cancer Res Treat 2015 Jul 23;152(2):313-21. Epub 2015 Jun 23.

The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University, CRB 1 Room 146, 1650 Orleans Street, Baltimore, MD, 21287, USA.

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http://dx.doi.org/10.1007/s10549-015-3468-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491111PMC
July 2015

Activation of human γδ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin.

J Immunol 2015 Mar 30;194(5):2390-8. Epub 2015 Jan 30.

Immunology Division, Department of Pathology, University of Cambridge, Cambridge Institute for Medical Research, Cambridge CB2 0XY, United Kingdom;

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http://dx.doi.org/10.4049/jimmunol.1401064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337483PMC
March 2015

Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly.

PLoS Pathog 2014 Oct 30;10(10):e1004459. Epub 2014 Oct 30.

Medical Research Council Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1004459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214760PMC
October 2014

CPSF6 defines a conserved capsid interface that modulates HIV-1 replication.

PLoS Pathog 2012 30;8(8):e1002896. Epub 2012 Aug 30.

Medical Research Council Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.ppat.1002896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431306PMC
September 2014

HIV-1 evades innate immune recognition through specific cofactor recruitment.

Nature 2013 Nov 6;503(7476):402-405. Epub 2013 Nov 6.

University College London, Medical Research Council Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 90 Gower St, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1038/nature12769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928559PMC
November 2013

HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358.

Retrovirology 2013 Jul 31;10:81. Epub 2013 Jul 31.

Protein and Nucleic Acid Chemistry Division, Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK.

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http://retrovirology.biomedcentral.com/articles/10.1186/1742
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http://dx.doi.org/10.1186/1742-4690-10-81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750474PMC
July 2013

Diverse HIV viruses are targeted by a conformationally dynamic antiviral.

Nat Struct Mol Biol 2012 Mar 11;19(4):411-6. Epub 2012 Mar 11.

Medical Research Council Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Cambridge, UK.

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http://dx.doi.org/10.1038/nsmb.2253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407371PMC
March 2012

Potent lentiviral restriction by a synthetic feline TRIM5 cyclophilin A fusion.

J Virol 2010 Sep 16;84(17):8980-5. Epub 2010 Jun 16.

Retrovirus Research Laboratory, Institute of Comparative Medicine, Faculty of Veterinary Medicine, University of Glasgow, Bearsden Road, Glasgow G61 1QH, United Kingdom.

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http://dx.doi.org/10.1128/JVI.00858-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919025PMC
September 2010

Conformational adaptation of Asian macaque TRIMCyp directs lineage specific antiviral activity.

PLoS Pathog 2010 Aug 19;6(8):e1001062. Epub 2010 Aug 19.

University College London Medical Research Council Centre for Medical Molecular Virology, London, UK.

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http://dx.doi.org/10.1371/journal.ppat.1001062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924388PMC
August 2010

Active site remodeling switches HIV specificity of antiretroviral TRIMCyp.

Nat Struct Mol Biol 2009 Oct 20;16(10):1036-42. Epub 2009 Sep 20.

Protein and Nucleic Acid Chemistry Division, Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

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http://dx.doi.org/10.1038/nsmb.1667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556581PMC
October 2009

Reconstitution and analysis of the multienzyme Escherichia coli RNA degradosome.

J Mol Biol 2008 Oct 27;382(4):870-83. Epub 2008 Jul 27.

Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.

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http://dx.doi.org/10.1016/j.jmb.2008.07.059DOI Listing
October 2008

Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

Cell Stem Cell 2007 Sep;1(3):338-45

Molecular Haematology and Cancer Biology Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK.

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http://dx.doi.org/10.1016/j.stem.2007.07.002DOI Listing
September 2007

Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex.

J Mol Biol 2007 May 7;368(3):639-51. Epub 2007 Feb 7.

Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.

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http://dx.doi.org/10.1016/j.jmb.2007.01.080DOI Listing
May 2007