Amancio Carnero

Amancio Carnero

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Amancio Carnero

Publications by authors named "Amancio Carnero"

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Downregulation of MYPT1 increases tumor resistance in ovarian cancer by targeting the Hippo pathway and increasing the stemness.

Mol Cancer 2020 Jan 11;19(1). Epub 2020 Jan 11.

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n 41013, Seville, Spain.

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http://dx.doi.org/10.1186/s12943-020-1130-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954568PMC
January 2020

The Tumor Suppressor Roles of MYBBP1A, a Major Contributor to Metabolism Plasticity and Stemness.

Cancers (Basel) 2020 Jan 20;12(1). Epub 2020 Jan 20.

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n, 41013 Seville, Spain.

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http://dx.doi.org/10.3390/cancers12010254DOI Listing
January 2020

c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer.

Mol Oncol 2019 07 11;13(7):1519-1533. Epub 2019 Jun 11.

Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío (HUVR), Consejo Superior de Investigaciones Científicas, Universidad de Sevilla, Spain.

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http://dx.doi.org/10.1002/1878-0261.12499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599841PMC
July 2019

Impact of Heat Shock Protein 90 Inhibition on the Proteomic Profile of Lung Adenocarcinoma as Measured by Two-Dimensional Electrophoresis Coupled with Mass Spectrometry.

Cells 2019 07 31;8(8). Epub 2019 Jul 31.

H12O-CNIO Lung Cancer Clinical Research Unit, Instituto de Investigación Hospital 12 de Octubre & Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.

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http://dx.doi.org/10.3390/cells8080806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721529PMC
July 2019

FGFR4 increases EGFR oncogenic signaling in lung adenocarcinoma, and their combined inhibition is highly effective.

Lung Cancer 2019 05 8;131:112-121. Epub 2019 Feb 8.

H120-CNIO Lung Cancer Clinical Cancer Research Unit, Fundación de Investigación Biomédica i+12 & Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain; Medical Oncology Department, Hospital Universitario Doce de Octubre & Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain; Medical School, Universidad Complutense, Madrid, Spain; CIBERONC, Madrid, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002193032
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http://dx.doi.org/10.1016/j.lungcan.2019.02.007DOI Listing
May 2019

FGFR1 Cooperates with EGFR in Lung Cancer Oncogenesis, and Their Combined Inhibition Shows Improved Efficacy.

J Thorac Oncol 2019 04 9;14(4):641-655. Epub 2019 Jan 9.

H12O-CNIO Lung Cancer Clinical Research Unit, Biomedical Research Foundation i+12, Madrid, Spain; H12O-CNIO Lung Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain; CIBERONC, Madrid, Spain; Medical Oncology Department, University Hospital Doce de Octubre Madrid, Spain; Medical School, Complutense University, Madrid, Spain.

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http://dx.doi.org/10.1016/j.jtho.2018.12.021DOI Listing
April 2019

Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment.

Oncogene 2019 02 10;38(8):1309-1323. Epub 2018 Oct 10.

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n, 41013, Seville, Spain.

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http://dx.doi.org/10.1038/s41388-018-0527-2DOI Listing
February 2019

Loss of MYBBP1A Induces Cancer Stem Cell Activity in Renal Cancer.

Cancers (Basel) 2019 Feb 18;11(2). Epub 2019 Feb 18.

Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío (HUVR), Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, 41013 Seville, Spain.

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http://dx.doi.org/10.3390/cancers11020235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406377PMC
February 2019

Dr. Jekyll and Mr. Hyde: MAP17's up-regulation, a crosspoint in cancer and inflammatory diseases.

Mol Cancer 2018 04 12;17(1):80. Epub 2018 Apr 12.

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/ Universidad de Sevilla/Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n, 41013, Sevilla, Spain.

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http://dx.doi.org/10.1186/s12943-018-0828-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896160PMC
April 2018

Is a Potent Oncogene in Colon Cancer Progression that Modulates Cancer Stem Cell Properties and Resistance to Therapy through Sirt1 and PARP.

Clin Cancer Res 2018 03 4;24(5):1202-1215. Epub 2017 Dec 4.

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocio, Universidad de Sevilla, Consejo Superior de Investigaciones Cientificas, Sevilla, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2575DOI Listing
March 2018

The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction.

Sci Rep 2018 02 5;8(1):2394. Epub 2018 Feb 5.

Medical Oncology Department, Hospital Universitario Doce de Octubre & Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.

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http://www.nature.com/articles/s41598-018-20570-3
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http://dx.doi.org/10.1038/s41598-018-20570-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799167PMC
February 2018

NUMB and NUMBL differences in gene regulation.

Oncotarget 2018 Feb 11;9(10):9219-9234. Epub 2018 Jan 11.

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.24186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823667PMC
February 2018

Genome-Wide miRNA Screening for Genes Bypassing Oncogene-Induced Senescence.

Methods Mol Biol 2017 ;1534:53-68

Molecular Biology of Cancer Group, Oncohematology and Genetic Department, Instituto de Biomedicina de Sevilla (IBIS/HUVR/CSIC/Universidad de Sevilla), Campus HUVR, Edificio IBIS, Avda. Manuel Siurot s/n. 41013, Sevilla, Spain.

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http://dx.doi.org/10.1007/978-1-4939-6670-7_5DOI Listing
January 2018

Coordinated downregulation of Spinophilin and the catalytic subunits of PP1, PPP1CA/B/C, contributes to a worse prognosis in lung cancer.

Oncotarget 2017 Dec 26;8(62):105196-105210. Epub 2017 Oct 26.

Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Sevilla, Spain.

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http://dx.doi.org/10.18632/oncotarget.22111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739631PMC
December 2017

The cargo protein MAP17 (PDZK1IP1) regulates the immune microenvironment.

Oncotarget 2017 Nov 6;8(58):98580-98597. Epub 2017 Oct 6.

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/Universidad de Sevilla/Consejo Superior de Investigaciones Científicas, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.21651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716752PMC
November 2017

NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis.

Oncotarget 2017 Nov 28;8(59):99514-99530. Epub 2017 Aug 28.

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocio, Universidad de Sevilla, Consejo Superior de Investigaciones Cientificas, Sevilla, Spain.

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http://dx.doi.org/10.18632/oncotarget.20577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725111PMC
November 2017

Prognostic relevance of Src activation in stage II-III colon cancer.

Hum Pathol 2017 09 7;67:119-125. Epub 2017 Jun 7.

Laboratorio de Oncología Traslacional y Nuevas Terapias, Instituto de Investigacion i+12 and Centro Nacional de Investigación Oncológica (CNIO), 28029 Madrid, Spain; Oncology Department, Hospital Universitario Doce de Octubre (Center Affiliated to the Spanish Cancer Networks (RTICC: R12/0036/0008 and R12/0036/0028, and CIBER-ONC: CB16/12/00442), Instituto Carlos III, Spanish Ministry of Science and Innovation), Universidad Complutense de Madrid (UCM), 28041 Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2017.05.025DOI Listing
September 2017

Inflammation and stem markers association to PIM1/PIM2 kinase-induced tumors in breast and uterus.

Oncotarget 2017 Aug 22;8(35):58872-58886. Epub 2017 Jul 22.

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.19438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601700PMC
August 2017

The Cargo Protein MAP17 (PDZK1IP1) Regulates the Cancer Stem Cell Pool Activating the Notch Pathway by Abducting NUMB.

Clin Cancer Res 2017 Jul 2;23(14):3871-3883. Epub 2017 Feb 2.

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocio/Universidad de Sevilla/Consejo Superior de Investigaciones Cientificas, Seville, Spain.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-2358DOI Listing
July 2017

The role of PIM1/PIM2 kinases in tumors of the male reproductive system.

Sci Rep 2016 11 30;6:38079. Epub 2016 Nov 30.

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/Universidad de Sevilla/Consejo Superior de Investigaciones Científicas, Avda. Manuel Siurot s/n 41013, Seville, Spain.

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http://dx.doi.org/10.1038/srep38079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128923PMC
November 2016

Efficacy of bortezomib in sarcomas with high levels of MAP17 (PDZK1IP1).

Oncotarget 2016 10;7(41):67033-67046

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocio, Universidad de Sevilla, Consejo Superior de Investigaciones Cientificas, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.11475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341855PMC
October 2016

Numb-like (NumbL) downregulation increases tumorigenicity, cancer stem cell-like properties and resistance to chemotherapy.

Oncotarget 2016 09;7(39):63611-63628

Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocio, Universidad de Sevilla, Consejo Superior de Investigaciones Cientificas, Seville, Spain.

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http://www.oncotarget.com/fulltext/11553
Publisher Site
http://dx.doi.org/10.18632/oncotarget.11553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325389PMC
September 2016

The hypoxic microenvironment: A determinant of cancer stem cell evolution.

Bioessays 2016 07;38 Suppl 1:S65-74

Pathology Department, Oncology and Pathology Group, Institut de Recerca Hospital Vall d'Hebron, Barcelona, Spain.

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http://dx.doi.org/10.1002/bies.201670911DOI Listing
July 2016

A genetic view of laryngeal cancer heterogeneity.

Cell Cycle 2016 05 3;15(9):1202-12. Epub 2016 Mar 3.

a Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas , Seville , Spain.

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http://dx.doi.org/10.1080/15384101.2016.1156275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894505PMC
May 2016

Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src.

Oncotarget 2016 May;7(22):33111-24

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/ Universidad de Sevilla/Consejo Superior de Investigaciones Científicas, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.8880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078079PMC
May 2016

Phosphorylation of gH2AX as a novel prognostic biomarker for laryngoesophageal dysfunction-free survival.

Oncotarget 2016 May;7(22):31723-37

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocío/ Universidad de Sevilla/ Consejo Superior de Investigaciones Científicas, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.9172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077972PMC
May 2016

MicroRNA-dependent regulation of transcription in non-small cell lung cancer.

PLoS One 2014 13;9(3):e90524. Epub 2014 Mar 13.

Molecular Oncology and New Therapies Group. Instituto de Biomedicina de Sevilla (IBIS) (HUVR, CSIC, Universidad de Sevilla), Sevilla, Spain; Medical Oncology Department, Hospital Universitario Virgen del Rocio, Sevilla, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090524PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953115PMC
January 2016

Decoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chain.

Oncotarget 2015 Dec;6(39):41582-99

Instituto de Biomedicina de Sevilla (IBIS), HUVR/CSIC/Universidad de Sevilla, Sevilla, Spain.

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http://dx.doi.org/10.18632/oncotarget.6057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747175PMC
December 2015

Efficacy of CDK4 inhibition against sarcomas depends on their levels of CDK4 and p16ink4 mRNA.

Oncotarget 2015 Dec;6(38):40557-74

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocio/Universidad de Sevilla/Consejo Superior de Investigaciones Cientificas, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.5829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747352PMC
December 2015

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Authors:
Keith I Block Charlotte Gyllenhaal Leroy Lowe Amedeo Amedei A R M Ruhul Amin Amr Amin Katia Aquilano Jack Arbiser Alexandra Arreola Alla Arzumanyan S Salman Ashraf Asfar S Azmi Fabian Benencia Dipita Bhakta Alan Bilsland Anupam Bishayee Stacy W Blain Penny B Block Chandra S Boosani Thomas E Carey Amancio Carnero Marianeve Carotenuto Stephanie C Casey Mrinmay Chakrabarti Rupesh Chaturvedi Georgia Zhuo Chen Helen Chen Sophie Chen Yi Charlie Chen Beom K Choi Maria Rosa Ciriolo Helen M Coley Andrew R Collins Marisa Connell Sarah Crawford Colleen S Curran Charlotta Dabrosin Giovanna Damia Santanu Dasgupta Ralph J DeBerardinis William K Decker Punita Dhawan Anna Mae E Diehl Jin-Tang Dong Q Ping Dou Janice E Drew Eyad Elkord Bassel El-Rayes Mark A Feitelson Dean W Felsher Lynnette R Ferguson Carmela Fimognari Gary L Firestone Christian Frezza Hiromasa Fujii Mark M Fuster Daniele Generali Alexandros G Georgakilas Frank Gieseler Michael Gilbertson Michelle F Green Brendan Grue Gunjan Guha Dorota Halicka William G Helferich Petr Heneberg Patricia Hentosh Matthew D Hirschey Lorne J Hofseth Randall F Holcombe Kanya Honoki Hsue-Yin Hsu Gloria S Huang Lasse D Jensen Wen G Jiang Lee W Jones Phillip A Karpowicz W Nicol Keith Sid P Kerkar Gazala N Khan Mahin Khatami Young H Ko Omer Kucuk Rob J Kulathinal Nagi B Kumar Byoung S Kwon Anne Le Michael A Lea Ho-Young Lee Terry Lichtor Liang-Tzung Lin Jason W Locasale Bal L Lokeshwar Valter D Longo Costas A Lyssiotis Karen L MacKenzie Meenakshi Malhotra Maria Marino Maria L Martinez-Chantar Ander Matheu Christopher Maxwell Eoin McDonnell Alan K Meeker Mahya Mehrmohamadi Kapil Mehta Gregory A Michelotti Ramzi M Mohammad Sulma I Mohammed D James Morre Vinayak Muralidhar Irfana Muqbil Michael P Murphy Ganji Purnachandra Nagaraju Rita Nahta Elena Niccolai Somaira Nowsheen Carolina Panis Francesco Pantano Virginia R Parslow Graham Pawelec Peter L Pedersen Brad Poore Deepak Poudyal Satya Prakash Mark Prince Lizzia Raffaghello Jeffrey C Rathmell W Kimryn Rathmell Swapan K Ray Jörg Reichrath Sarallah Rezazadeh Domenico Ribatti Luigi Ricciardiello R Brooks Robey Francis Rodier H P Vasantha Rupasinghe Gian Luigi Russo Elizabeth P Ryan Abbas K Samadi Isidro Sanchez-Garcia Andrew J Sanders Daniele Santini Malancha Sarkar Tetsuro Sasada Neeraj K Saxena Rodney E Shackelford H M C Shantha Kumara Dipali Sharma Dong M Shin David Sidransky Markus David Siegelin Emanuela Signori Neetu Singh Sharanya Sivanand Daniel Sliva Carl Smythe Carmela Spagnuolo Diana M Stafforini John Stagg Pochi R Subbarayan Tabetha Sundin Wamidh H Talib Sarah K Thompson Phuoc T Tran Hendrik Ungefroren Matthew G Vander Heiden Vasundara Venkateswaran Dass S Vinay Panagiotis J Vlachostergios Zongwei Wang Kathryn E Wellen Richard L Whelan Eddy S Yang Huanjie Yang Xujuan Yang Paul Yaswen Clement Yedjou Xin Yin Jiyue Zhu Massimo Zollo

Semin Cancer Biol 2015 Dec;35 Suppl:S276-S304

Centro di Ingegneria Genetica e Biotecnologia Avanzate, Naples, Italy; Department of Molecular Medicine and Medical Biotechnology, Federico II, Via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.semcancer.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819002PMC
December 2015

MAP17 (PDZKIP1) Expression Determines Sensitivity to the Proteasomal Inhibitor Bortezomib by Preventing Cytoprotective Autophagy and NFκB Activation in Breast Cancer.

Mol Cancer Ther 2015 Jun 2;14(6):1454-65. Epub 2015 Apr 2.

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocio/Universidad de Sevilla/Consejo Superior de Investigaciones Cientificas, Seville, Spain.

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http://dx.doi.org/10.1158/1535-7163.MCT-14-1053DOI Listing
June 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

MAP17 (PDZKIP1) as a novel prognostic biomarker for laryngeal cancer.

Oncotarget 2015 May;6(14):12625-36

Instituto de Biomedicina de Sevilla, IBIS, Hospital Universitario Virgen del Rocío, Universidad de Sevilla, Consejo Superior de Investigaciones Científicas, Seville, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494962PMC
http://dx.doi.org/10.18632/oncotarget.3470DOI Listing
May 2015

Prognostic relevance of estrogen receptor-α Ser167 phosphorylation in stage II-III colon cancer patients.

Hum Pathol 2014 Dec 2;45(12):2437-46. Epub 2014 Sep 2.

Instituto de Biomedicina de Sevilla (IBIS), HUVR/CSIC/Universidad de Sevilla, Center affiliated to the Red Temática de Investigación Cooperativa en Cancer (RTICC), Instituto Carlos III, Spanish Ministry of Science and Innovation, Seville, 41013, Spain; Department of Medical Oncology, Hospital Universitario Virgen del Rocío, Center affiliated to the Red Temática de Investigación Cooperativa en Cancer (RTICC), Instituto Carlos III, Spanish Ministry of Science and Innovation, Seville, 41013, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2014.08.008DOI Listing
December 2014

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models.

Front Oncol 2014 23;4:252. Epub 2014 Sep 23.

Molecular Oncology Unit, Division of Biomedicine, CIEMAT , Madrid , Spain ; Oncogenomics Unit, Biomedical Research Institute, "12 de Octubre" University Hospital , Madrid , Spain.

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http://dx.doi.org/10.3389/fonc.2014.00252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172058PMC
October 2014

MicroRNA clusters: dysregulation in lung adenocarcinoma and COPD.

Eur Respir J 2014 Jun 17;43(6):1740-9. Epub 2014 Apr 17.

Instituto de Biomedicina de Sevilla (IBIS), HUVR, CSIC, Universidad de Sevilla, Seville, Spain Medical Oncology Dept, Hospital Universitario Virgen del Rocío, Seville, Spain

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http://dx.doi.org/10.1183/09031936.00091513DOI Listing
June 2014

Levels of active tyrosine kinase receptor determine the tumor response to Zalypsis.

BMC Cancer 2014 Apr 23;14:281. Epub 2014 Apr 23.

Instituto de Biomedicina de Sevilla, IBIS/Hospital Universitario Virgen del Rocio/CSIC/Universidad de Sevilla, Sevilla, Spain.

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http://dx.doi.org/10.1186/1471-2407-14-281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023704PMC
April 2014

The PIM family of serine/threonine kinases in cancer.

Med Res Rev 2014 Jan 10;34(1):136-59. Epub 2013 Apr 10.

Experimental Therapeutics Programme, Spanish National Cancer Research Centre, Madrid, Spain.

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http://dx.doi.org/10.1002/med.21284DOI Listing
January 2014

The second generation of iodido complexes: trans-[PtI2(amine)(amine')] bearing different aliphatic amines.

J Inorg Biochem 2013 Oct 28;127:182-7. Epub 2013 Apr 28.

Departamento de Química Inorgánica, Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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http://dx.doi.org/10.1016/j.jinorgbio.2013.04.010DOI Listing
October 2013

MAP17 and SGLT1 protein expression levels as prognostic markers for cervical tumor patient survival.

PLoS One 2013 13;8(2):e56169. Epub 2013 Feb 13.

Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocio, Consejo Superior de Investigaciones Cientificas, Universidad de Sevilla, Sevilla, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056169PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572015PMC
August 2013

Inhibition of HSP90 molecular chaperones: moving into the clinic.

Lancet Oncol 2013 Aug;14(9):e358-69

Laboratorio de Oncología Molecular y Nuevas Terapias, Instituto de Biomedicina de Sevilla (HUVR/CSIC/Universidad de Sevilla), Sevilla, Spain.

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http://dx.doi.org/10.1016/S1470-2045(13)70169-4DOI Listing
August 2013

Markers of cellular senescence.

Authors:
Amancio Carnero

Methods Mol Biol 2013 ;965:63-81

Instituto de Biomedicina, Hospital Universitario Virgen del Rocio, Sevilla, Spain.

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http://dx.doi.org/10.1007/978-1-62703-239-1_4DOI Listing
June 2013

Pim kinases in cancer: diagnostic, prognostic and treatment opportunities.

Biochem Pharmacol 2013 Mar 5;85(5):629-643. Epub 2012 Oct 5.

Instituto de Biomedicina de Sevilla (IBiS), HUVR/CSIC/Universidad de Sevilla, Sevilla, Spain; Consejo Superior de Investigaciones Cientificas, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2012.09.018DOI Listing
March 2013

MAP17, a ROS-dependent oncogene.

Authors:
Amancio Carnero

Front Oncol 2012 6;2:112. Epub 2012 Sep 6.

Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío, Consejo Superior de Investigaciones Cientificas, Universidad de Sevilla Sevilla, Spain.

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http://dx.doi.org/10.3389/fonc.2012.00112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434504PMC
September 2012

MAP17 and the double-edged sword of ROS.

Authors:
Amancio Carnero

Biochim Biophys Acta 2012 Aug 23;1826(1):44-52. Epub 2012 Mar 23.

Instituto de Biomedicina de Sevilla (IBIS), HUVR/CSIC/Universidad de Sevilla, Consejo Superior de Investigaciones Cientificas, Campus Hospital Universitario Virgen del Rocío, Sevilla, Spain.

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http://dx.doi.org/10.1016/j.bbcan.2012.03.004DOI Listing
August 2012

The essential role of PIM kinases in sarcoma growth and bone invasion.

Carcinogenesis 2012 Aug 22;33(8):1479-86. Epub 2012 May 22.

Experimental Therapeutics Programme, Spanish National Cancer Research Centre Madrid, Spain.

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http://dx.doi.org/10.1093/carcin/bgs176DOI Listing
August 2012

Cancer, senescence, and aging: translation from basic research to clinics.

J Aging Res 2011 20;2011:692301. Epub 2011 Oct 20.

Oncología y Patología Grupo, Vall d'Hebron Institut de Recerca, 08035 Barcelona, Spain.

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http://dx.doi.org/10.4061/2011/692301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199198PMC
November 2011

Spinophilin acts as a tumor suppressor by regulating Rb phosphorylation.

Cell Cycle 2011 Aug 15;10(16):2751-62. Epub 2011 Aug 15.

Experimental Therapeutics Programme, Instituto de Biomedicina de Sevilla/HUVR, Sevilla, Spain.

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http://dx.doi.org/10.4161/cc.10.16.16422DOI Listing
August 2011

Spinophilin loss contributes to tumorigenesis in vivo.

Cell Cycle 2011 Jun 15;10(12):1948-55. Epub 2011 Jun 15.

Experimental Therapeutics Program, Spanish National Cancer Research Center, Madrid, Spain.

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http://dx.doi.org/10.4161/cc.10.12.15798DOI Listing
June 2011

Epigenetic mechanisms in senescence, immortalisation and cancer.

Biol Rev Camb Philos Soc 2011 May 16;86(2):443-55. Epub 2010 Sep 16.

Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocio, Av. Manuel Siurot s/n, Seville, Spain.

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http://dx.doi.org/10.1111/j.1469-185X.2010.00154.xDOI Listing
May 2011

The preparation and characterization of trans-platinum(IV) complexes with unusually high cytotoxicity.

Dalton Trans 2011 Jan 8;40(2):344-7. Epub 2010 Oct 8.

Universidad Autónoma Madrid, Department of Inorganic Chemistry, Madrid, 28049, Spain.

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http://dx.doi.org/10.1039/c0dt00565gDOI Listing
January 2011

The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras.

Carcinogenesis 2010 Dec 30;31(12):2145-54. Epub 2010 Sep 30.

Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC) and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), 28040 Madrid, Spain.

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http://dx.doi.org/10.1093/carcin/bgq199DOI Listing
December 2010

Cellular senescence as a target in cancer control.

J Aging Res 2010 Dec 30;2011:725365. Epub 2010 Dec 30.

Instituto de Biomedicina de Sevilla, Hospital Universitario virgen del Rocio, 41013 Sevilla, Spain.

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http://dx.doi.org/10.4061/2011/725365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018654PMC
December 2010

Between bench and bed side: PI3K inhibitors.

Curr Mol Pharmacol 2010 Jun;3(2):79-90

Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocio, Sevilla, Spain.

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http://dx.doi.org/10.2174/1874467211003020079DOI Listing
June 2010

Bypassing cellular senescence by genetic screening tools.

Clin Transl Oncol 2010 Jun;12(6):410-7

Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío, Sevilla, Spain.

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http://link.springer.com/content/pdf/10.1007/s12094-010-0528
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http://dx.doi.org/10.1007/s12094-010-0528-2DOI Listing
June 2010

Understanding FOXO, new views on old transcription factors.

Curr Cancer Drug Targets 2010 Mar;10(2):135-46

Experimental Therapeutics programme, Spanish National Cancer Research Centre, Madrid, Spain.

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http://dx.doi.org/10.2174/156800910791054158DOI Listing
March 2010

The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine.

Eur J Med Chem 2010 Jan 1;45(1):134-41. Epub 2009 Oct 1.

Departamento de Química Inorgánica, Universidad Autónoma de Madrid, Francisco Tomas y Valiente 7, 28049 Madrid, Spain.

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http://dx.doi.org/10.1016/j.ejmech.2009.09.035DOI Listing
January 2010

The PKB/AKT pathway in cancer.

Authors:
Amancio Carnero

Curr Pharm Des 2010 Jan;16(1):34-44

Experimental Therapeutics Programme, Spanish National Cancer Centre (CNIO), C/Melchor Fernandez Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.2174/138161210789941865DOI Listing
January 2010

Using cells devoid of RAS proteins as tools for drug discovery.

Mol Carcinog 2009 Nov;48(11):1038-47

Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/mc.20555DOI Listing
November 2009

Adding more content to screening: reactivation of FOXO as a therapeutic strategy.

Clin Transl Oncol 2009 Oct;11(10):651-8

Experimental Therapeutics Programme, Spanish National Cancer Research Centre, Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-009-0420-0DOI Listing
October 2009

Novel inhibitors of the PI3K family.

Authors:
Amancio Carnero

Expert Opin Investig Drugs 2009 Sep;18(9):1265-77

Centro Nacional de Investigaciones Oncologicas, Experimental Therapeutics Program, Melchor Fernandez Almagro, 3, Madrid, 28029, Spain.

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http://dx.doi.org/10.1517/13543780903066798DOI Listing
September 2009

Inhibiting PI3K as a therapeutic strategy against cancer.

Clin Transl Oncol 2009 Sep;11(9):572-9

Medical Oncology, Hospital Universitario Virgen del Rocío, Sevilla, Spain.

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http://dx.doi.org/10.1007/s12094-009-0407-xDOI Listing
September 2009

Mouse models to decipher the PI3K signaling network in human cancer.

Curr Mol Med 2009 Jun;9(5):612-25

Experimental Therapeutics Program, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain.

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http://dx.doi.org/10.2174/156652409788488766DOI Listing
June 2009

Influence of amine ligands on the aquation and cytotoxicity of trans-diamine platinum(II) anticancer complexes.

Dalton Trans 2009 May 29(18):3457-66. Epub 2009 Jan 29.

Departamento de Química Inorgánica, Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1039/b819301kDOI Listing
May 2009

Using multiplexed regulation of luciferase activity and GFP translocation to screen for FOXO modulators.

BMC Cell Biol 2009 Feb 25;10:14. Epub 2009 Feb 25.

Experimental Therapeutics Programme, Centro Nacional de Investigaciones Oncologicas, Melchor Fernandez Almagro 3, 28029 Madrid, Spain.

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http://bmccellbiol.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2121-10-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2651847PMC
February 2009

Activation of phosphatidylinositol 3-kinase by membrane localization of p110alpha predisposes mammary glands to neoplastic transformation.

Cancer Res 2008 Dec;68(23):9643-53

Experimental Therapeutics Program and Biotechnology Program, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1539DOI Listing
December 2008

Genetic modelling of the PTEN/AKT pathway in cancer research.

Clin Transl Oncol 2008 Oct;10(10):618-27

Experimental Therapeutics Programme, Spanish National Cancer Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1007/s12094-008-0262-1DOI Listing
October 2008

Battling cancer on many fronts. Meeting on New Battlefields in Human Cancer--Attacking in Many Fronts.

EMBO Rep 2008 Sep;9(9):853-8

Experimental Therapeutics Programme, Centro Nacional de Investigaciones Oncologicas, Madrid, Spain.

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http://dx.doi.org/10.1038/embor.2008.140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529353PMC
September 2008

Chemical genetic analysis of FOXO nuclear-cytoplasmic shuttling by using image-based cell screening.

Chembiochem 2008 Sep;9(14):2229-37

Experimental Therapeutics Program, Centro Nacional de Investigaciones Oncologicas (CNIO), Melchor Fernandez Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.1002/cbic.200800255DOI Listing
September 2008

Characterization of the p53 response to oncogene-induced senescence.

PLoS One 2008 Sep 18;3(9):e3230. Epub 2008 Sep 18.

Experimental Therapeutics Programme, Centro Nacional De Investigaciones Oncológicas, Madrid, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003230PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2535567PMC
September 2008

Mitotic catastrophe cell death induced by heat shock protein 90 inhibitor in BRCA1-deficient breast cancer cell lines.

Mol Cancer Ther 2008 Aug;7(8):2358-66

Grupo Genética Humana, Centro Nacional de Investigaciones Oncológicas, Melchor Fernández Almagro 3, Madrid, Spain.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-08
Publisher Site
http://dx.doi.org/10.1158/1535-7163.MCT-08-0327DOI Listing
August 2008