Amaia Lujambio

Amaia Lujambio

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Amaia Lujambio

Amaia Lujambio

Publications by authors named "Amaia Lujambio"

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41Publications

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Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation.

Cancer Cell 2020 Apr 26;37(4):584-598.e11. Epub 2020 Mar 26.

Department of Molecular Biology, UT Southwestern Medical Center, Dallas, TX 75390, USA; Hamon Center for Regenerative Science and Medicine, UT Southwestern Medical Center, Dallas, TX 75390, USA; Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2020.03.001DOI Listing
April 2020

Mouse models of oncoimmunology in hepatocellular carcinoma.

Clin Cancer Res 2020 Apr 23. Epub 2020 Apr 23.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai

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http://dx.doi.org/10.1158/1078-0432.CCR-19-2923DOI Listing
April 2020

Novel patient-derived preclinical models of liver cancer.

J Hepatol 2020 Feb;72(2):239-249

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, USA; Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; The Precision Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, USA; Graduate School of Biomedical Sciences at Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.09.028DOI Listing
February 2020

Hepatocellular carcinoma: killing one bird with two stones.

Gut 2019 09 10;68(9):1543-1544. Epub 2019 May 10.

Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2019-318649
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http://dx.doi.org/10.1136/gutjnl-2019-318649DOI Listing
September 2019

Epigenetic Compensation Promotes Liver Regeneration.

Dev Cell 2019 07 20;50(1):43-56.e6. Epub 2019 Jun 20.

Department of Medicine/Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Program in Biology, New York University Abu Dhabi, Abu Dhabi, P.O. Box 129188, United Arab Emirates. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.05.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615735PMC
July 2019

Iron overload and liver cancer.

J Exp Med 2019 04 18;216(4):723-724. Epub 2019 Mar 18.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY

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http://dx.doi.org/10.1084/jem.20190257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446872PMC
April 2019

Functional screening to identify senescence regulators in cancer.

Curr Opin Genet Dev 2019 02 14;54:17-24. Epub 2019 Mar 14.

Hopp Children's Cancer Center (KiTZ) and Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2019.02.001DOI Listing
February 2019

Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import.

Cell 2018 08 9;174(5):1200-1215.e20. Epub 2018 Aug 9.

Cancer Biology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Medical Oncology Department, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA; Pathology Department, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6150493PMC
August 2018

Cell type-specific pharmacological kinase inhibition for cancer chemoprevention.

Nanomedicine 2018 02 20;14(2):317-325. Epub 2017 Nov 20.

Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844817PMC
February 2018

Erratum: DNA sensing in senescence.

Nat Cell Biol 2017 11;19(12):1441

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http://www.nature.com/doifinder/10.1038/ncb3644
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http://dx.doi.org/10.1038/ncb3644DOI Listing
November 2017

Therapeutic editing of hepatocyte genome in vivo.

J Hepatol 2017 10 17;67(4):818-828. Epub 2017 May 17.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, USA; Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, USA; Graduate School of Biomedical Sciences at Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.05.012DOI Listing
October 2017

DNA sensing in senescence.

Nat Cell Biol 2017 08;19(9):1008-1009

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York 10029, USA and at the Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York 10029, USA.

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http://dx.doi.org/10.1038/ncb3603DOI Listing
August 2017

Strategies for HCC target discovery.

Aging (Albany NY) 2017 Apr;9(4):1088-1089

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.18632/aging.101233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425115PMC
April 2017

USP39 Deubiquitinase Is Essential for Oncogene-driven Cancer.

J Biol Chem 2017 03 1;292(10):4164-4175. Epub 2017 Feb 1.

From the Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología (IUOPA), Universidad de Oviedo, 33006 Oviedo, Spain,

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http://dx.doi.org/10.1074/jbc.M116.762757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354494PMC
March 2017

Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway.

Cell Rep 2017 03;18(10):2480-2493

Epigenetics & Cellular Senescence Group, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357738PMC
March 2017

Uncovering the role of USP54 in cancer.

Oncotarget 2017 Feb;8(7):10765-10766

Department of Oncological Sciences and Department of Medicine, Liver Cancer Program, Division of Liver Diseases, Graduate School of Biomedical Sciences at Icahn School of Medicine at Mount Sinai, New York, USA.

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http://dx.doi.org/10.18632/oncotarget.14820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355214PMC
February 2017

IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models.

Gastroenterology 2016 12 7;151(6):1192-1205. Epub 2016 Sep 7.

Liver Cancer Translational Research Laboratory, Barcelona Clinic Liver Cancer Group, Liver Unit, IDIBAPS-Hospital Clínic de Barcelona, CIBERehd Universitat de Barcelona, Catalonia, Spain; Liver Cancer Program, Division of Liver Diseases and Pathology Department, Tisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; Institució Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.09.001DOI Listing
December 2016

An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling.

Cancer Cell 2016 09 11;30(3):485-498. Epub 2016 Aug 11.

Department of Oncological Sciences, Department of Dermatology, The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021590PMC
September 2016

To clear, or not to clear (senescent cells)? That is the question.

Authors:
Amaia Lujambio

Bioessays 2016 07;38 Suppl 1:S56-64

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1002/bies.201670910DOI Listing
July 2016

The usual SASPects of liver cancer.

Aging (Albany NY) 2015 Jun;7(6):348-9

Liver Cancer Program, Division of Liver Diseases, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505156PMC
http://dx.doi.org/10.18632/aging.100758DOI Listing
June 2015

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.

Genes Dev 2014 Aug;28(16):1800-14

Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA; Cell and Developmental Biology Program, Weill Graduate School of Medical Sciences, Cornell University, New York, New York 10065, USA; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA; Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA;

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http://dx.doi.org/10.1101/gad.244368.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197965PMC
August 2014

Epigenetic disruption of cadherin-11 in human cancer metastasis.

J Pathol 2012 Oct 26;228(2):230-40. Epub 2012 Jul 26.

Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.

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http://dx.doi.org/10.1002/path.4011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467766PMC
October 2012

The microcosmos of cancer.

Nature 2012 Feb 15;482(7385):347-55. Epub 2012 Feb 15.

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.

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http://www.nature.com/articles/nature10888
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http://dx.doi.org/10.1038/nature10888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509753PMC
February 2012

Bivalent histone modifications in stem cells poise miRNA loci for CpG island hypermethylation in human cancer.

Epigenetics 2011 Nov 1;6(11):1344-53. Epub 2011 Nov 1.

Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Catalonia, Spain.

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http://www.tandfonline.com/doi/abs/10.4161/epi.6.11.18021
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http://dx.doi.org/10.4161/epi.6.11.18021DOI Listing
November 2011

How epigenetics can explain human metastasis: a new role for microRNAs.

Cell Cycle 2009 Feb 1;8(3):377-82. Epub 2009 Feb 1.

Cancer Epigenetics and Biology Program, Catalan Institute of Oncology, Bellvitge Biomedical Research Institute, IDIBELL, Institucio Catalana de Recerca i Estudis Avançats, Barcelona, Catalonia, Spain.

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http://www.tandfonline.com/doi/abs/10.4161/cc.8.3.7526
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http://dx.doi.org/10.4161/cc.8.3.7526DOI Listing
February 2009

A microRNA DNA methylation signature for human cancer metastasis.

Proc Natl Acad Sci U S A 2008 Sep 3;105(36):13556-61. Epub 2008 Sep 3.

Cancer Epigenetics Laboratory, Spanish National Cancer Research Center, Melchor Fernández Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.1073/pnas.0803055105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2528872PMC
September 2008

CpG island hypermethylation of tumor suppressor microRNAs in human cancer.

Cell Cycle 2007 Jun 4;6(12):1455-9. Epub 2007 May 4.

Cancer Epigenetics Laboratory, Spanish National Cancer Centre, Madrid, Spain.

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June 2007

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells.

Cancer Res 2007 Feb;67(4):1424-9

Cancer Epigenetics Laboratory and Lung Cancer Laboratory, Spanish National Cancer Centre (CNIO), Melchor Fernandez Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-4218DOI Listing
February 2007