Publications by authors named "Aly Karsan"

100Publications

Colorectal Cancer Detection Based on Deep Learning.

J Pathol Inform 2020 21;11:28. Epub 2020 Aug 21.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.4103/jpi.jpi_68_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7518343PMC
August 2020

Mechanisms of lenalidomide sensitivity and resistance.

Exp Hematol 2020 Oct 9. Epub 2020 Oct 9.

Michael Smith Genome Sciences Centre, BC Cancer Research Institute, Vancouver, BC, Canada; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2020.09.196DOI Listing
October 2020

Evaluating the quantity, quality and size distribution of cell-free DNA by multiplex droplet digital PCR.

Sci Rep 2020 Jul 28;10(1):12564. Epub 2020 Jul 28.

Department of Molecular Biology and Biochemistry, Simon Fraser University, 8888 University Drive, South Sciences Building (SSB) 7157, Burnaby, BC, V5A 1S6, Canada.

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http://dx.doi.org/10.1038/s41598-020-69432-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7387491PMC
July 2020

No Differences in Outcomes Between JAK2 V617F-Positive Patients with Variant Allele Fraction < 2% Versus 2-10%: A 6-Year Province-wide Retrospective Analysis.

Clin Lymphoma Myeloma Leuk 2020 Sep 21;20(9):e569-e578. Epub 2020 Apr 21.

Michael Smith Genome Sciences Centre, Vancouver, BC, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.clml.2020.04.010DOI Listing
September 2020

Sample Tracking Using Unique Sequence Controls.

J Mol Diagn 2020 02 16;22(2):141-146. Epub 2019 Dec 16.

Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, British Columbia; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2019.10.011DOI Listing
February 2020

Genomic testing in myeloid malignancy.

Int J Lab Hematol 2019 May;41 Suppl 1:117-125

Experimental Medicine Program, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1111/ijlh.13022DOI Listing
May 2019

Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling.

Cell Rep 2019 05;27(6):1769-1780.e4

Michael Smith Genome Sciences Centre, BC Cancer Agency, 675 West 10(th) Avenue, Vancouver, BC V5Z 1L3, Canada; Department of Experimental Medicine, University of British Columbia, Vancouver, BC V6T 2B5, Canada; Program of Interdisciplinary Oncology, University of British Columbia, Vancouver, BC V6T 2B5, Canada; Department of Pathology, University of British Colombia, Vancouver, BC V6T 2B5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.04.039DOI Listing
May 2019

Fixation Effects on Variant Calling in a Clinical Resequencing Panel.

J Mol Diagn 2019 07 2;21(4):705-717. Epub 2019 May 2.

Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15251578183019
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http://dx.doi.org/10.1016/j.jmoldx.2019.03.005DOI Listing
July 2019

High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations.

Stem Cell Reports 2018 08 2;11(2):578-592. Epub 2018 Aug 2.

Department of Microbiology and Immunology and Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, BC V5Z 1L3, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093082PMC
August 2018

Non-invasive prenatal aneuploidy testing: Critical diagnostic performance parameters predict sample z-score values.

Clin Biochem 2018 Sep 27;59:69-77. Epub 2018 Jun 27.

Service of Medical Biochemistry, Department of Medical Biology, CHU de Québec - Université Laval, Quebec, Canada; Department of Molecular Biology, Medical Biochemistry, and Pathology, Faculty of Medicine, Université Laval, Quebec, Canada; Human and Molecular Genetics Research Unit, Research Center, CHU de Québec, Quebec, Canada; PEGASUS, Quebec, Canada.

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http://dx.doi.org/10.1016/j.clinbiochem.2018.06.015DOI Listing
September 2018

Applications of Bayesian network models in predicting types of hematological malignancies.

Sci Rep 2018 05 3;8(1):6951. Epub 2018 May 3.

Department of Computer Science, Texas State University, San Marcos, Texas, 78666, USA.

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http://dx.doi.org/10.1038/s41598-018-24758-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934387PMC
May 2018

An actionable test using loss of heterozygosity in identifying high-risk oral premalignant lesions.

Oral Surg Oral Med Oral Pathol Oral Radiol 2017 Dec 18. Epub 2017 Dec 18.

Department of Oral Medical Biological Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada; Department of Integrative Oncology, BC Cancer Agency, Vancouver, BC, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.oooo.2017.10.019DOI Listing
December 2017

Development and Evaluation of a Pan-Sarcoma Fusion Gene Detection Assay Using the NanoString nCounter Platform.

J Mol Diagn 2018 01 20;20(1):63-77. Epub 2017 Nov 20.

Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada; Department of Pathology, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15251578173031
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http://dx.doi.org/10.1016/j.jmoldx.2017.09.007DOI Listing
January 2018

APELA promotes tumour growth and cell migration in ovarian cancer in a p53-dependent manner.

Gynecol Oncol 2017 12 24;147(3):663-671. Epub 2017 Oct 24.

Terry Fox Laboratory, BC Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada; Cell and Developmental Biology Program, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia V6T 1Z4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2017.10.016DOI Listing
December 2017

Detection and genomic characterization of a mammary-like adenocarcinoma.

Cold Spring Harb Mol Case Stud 2017 Nov 21;3(6). Epub 2017 Nov 21.

Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada.

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http://dx.doi.org/10.1101/mcs.a002170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701302PMC
November 2017

Chronic Lymphocytic Leukemia Patients With Deletion 11q Have a Short Time to Requirement of First-Line Therapy, But Long Overall Survival: Results of a Population-Based Cohort in British Columbia, Canada.

Clin Lymphoma Myeloma Leuk 2017 06 8;17(6):382-389. Epub 2017 May 8.

Leukemia/Bone Marrow Transplant Program of BC, British Columbia Cancer Agency, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.clml.2017.04.001DOI Listing
June 2017

The cost and cost trajectory of whole-genome analysis guiding treatment of patients with advanced cancers.

Mol Genet Genomic Med 2017 May 12;5(3):251-260. Epub 2017 Mar 12.

Canadian Centre for Applied Research in Cancer Control (ARCC)Cancer Control ResearchBC Cancer AgencyVancouverBritish ColumbiaCanada.

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http://dx.doi.org/10.1002/mgg3.281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441418PMC
May 2017

Clonal evolution as detected by interphase fluorescence in situ hybridization is associated with worse overall survival in a population-based analysis of patients with chronic lymphocytic leukemia in British Columbia, Canada.

Cancer Genet 2017 01 3;210:1-8. Epub 2016 Nov 3.

Division of Hematology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada; Leukemia/BMT Program of BC, Vancouver General Hospital and British Columbia Cancer Agency, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2016.10.006DOI Listing
January 2017

Characterization of treatment and outcomes in a population-based cohort of patients with chronic lymphocytic leukemia referred for cytogenetic testing in British Columbia, Canada.

Leuk Res 2017 04 15;55:79-90. Epub 2017 Jan 15.

Division of Hematology, Leukemia/BMT Program of BC, Vancouver General Hospital, British Columbia Cancer Agency and University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2017.01.023DOI Listing
April 2017

Laboratory Investigation of Myeloproliferative Neoplasms (MPNs):  Recommendations of the Canadian Mpn Group.

Am J Clin Pathol 2016 Oct;146(4):408-22

Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.1093/ajcp/aqw131DOI Listing
October 2016

Economic impact of genomic diagnostics for intermediate-risk acute myeloid leukaemia.

Br J Haematol 2016 08 21;174(4):526-35. Epub 2016 Apr 21.

Canadian Centre for Applied Research in Cancer Control (ARCC), Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/bjh.14076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021117PMC
August 2016

Initial Diagnosis of ALK-Positive Non-Small-Cell Lung Cancer Based on Analysis of ALK Status Utilizing Droplet Digital PCR.

Anal Chem 2016 05 12;88(9):4879-85. Epub 2016 Apr 12.

Michael Smith Laboratories, University of British Columbia , Vancouver, British Columbia V6T 1Z4, Canada.

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http://dx.doi.org/10.1021/acs.analchem.6b00707DOI Listing
May 2016

Quantitative Detection and Resolution of BRAF V600 Status in Colorectal Cancer Using Droplet Digital PCR and a Novel Wild-Type Negative Assay.

J Mol Diagn 2016 Mar 4;18(2):190-204. Epub 2016 Jan 4.

Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2015.09.003DOI Listing
March 2016

Initial diagnosis of chronic myelogenous leukemia based on quantification of M-BCR status using droplet digital PCR.

Anal Bioanal Chem 2016 Feb 2;408(4):1079-94. Epub 2015 Dec 2.

Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, V6T 1Z4, Canada.

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http://dx.doi.org/10.1007/s00216-015-9204-2DOI Listing
February 2016

Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling.

J Exp Med 2015 Oct 12;212(11):1967-85. Epub 2015 Oct 12.

Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229 Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH 45267

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http://jem.rupress.org/content/212/11/1967.full.pdf
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http://www.jem.org/lookup/doi/10.1084/jem.20141898
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http://dx.doi.org/10.1084/jem.20141898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612089PMC
October 2015

Influence of clone and deletion size on outcome in chronic lymphocytic leukemia patients with an isolated deletion 13q in a population-based analysis in British Columbia, Canada.

Genes Chromosomes Cancer 2016 Jan 22;55(1):16-24. Epub 2015 Sep 22.

Pathology and Laboratory Medicine, Vancouver General Hospital University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/gcc.22294DOI Listing
January 2016

A novel population of local pericyte precursor cells in tumor stroma that require Notch signaling for differentiation.

Microvasc Res 2015 Sep 17;101:38-47. Epub 2015 Jun 17.

Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.mvr.2015.05.004DOI Listing
September 2015

Deep profiling of multitube flow cytometry data.

Bioinformatics 2015 May 18;31(10):1623-31. Epub 2015 Jan 18.

Terry Fox Laboratory, BC Cancer Agency, Bioinformatics Graduate Program, University of British Columbia, Department of Hematopathology, Vancouver General Hospital and Faculty of Medical Genetics, University of British Columbia, Vancouver, Canada Terry Fox Laboratory, BC Cancer Agency, Bioinformatics Graduate Program, University of British Columbia, Department of Hematopathology, Vancouver General Hospital and Faculty of Medical Genetics, University of British Columbia, Vancouver, Canada.

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http://bioinformatics.oxfordjournals.org/content/early/2015/
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http://bioinformatics.oxfordjournals.org/content/early/2015/
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http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
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http://dx.doi.org/10.1093/bioinformatics/btv008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426837PMC
May 2015

Kleat: cleavage site analysis of transcriptomes.

Pac Symp Biocomput 2015 :347-58

Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, V5Z 4S6, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350765PMC
April 2016

Loss of the Notch effector RBPJ promotes tumorigenesis.

J Exp Med 2015 Jan 15;212(1):37-52. Epub 2014 Dec 15.

Genome Sciences Centre, Integrative Oncology Department, and Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada Genome Sciences Centre, Integrative Oncology Department, and Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada Experimental Medicine Program and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver V6T 2B5, British Columbia, Canada Experimental Medicine Program and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver V6T 2B5, British Columbia, Canada

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http://www.imls.uzh.ch/static/CMS_publications/robinson/lite
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http://www.jem.org/lookup/doi/10.1084/jem.20121192
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http://dx.doi.org/10.1084/jem.20121192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291530PMC
January 2015

Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer.

J Thorac Oncol 2014 Sep;9(9):1255-63

*Department of Pathology and Molecular Medicine, McMaster University Health Sciences Centre and McMaster University, Hamilton, Ontario; †Department of Pathology, University Health Network, Princess Margaret Cancer Centre and University of Toronto, Toronto, Ontario; ‡Department of Pathology, Jewish General Hospital and Lady David Institute, McGill University, Montreal, Québec; §Cross Cancer Institute and Department of Laboratory Medicine & Pathology, University of Alberta, Edmonton, Alberta; ‖Department of Molecular Pathology, University of Alberta Hospital, Edmonton, Alberta; ¶Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia; #Department of Pathology, Aichi Cancer Center Hospital, Nagoya, Japan; **Department of Pathology, British Columbia Cancer Agency and University of British Columbia, Vancouver, British Columbia; ††Department of Pathology, McGill University Health Centre, Montreal, Québec; ‡‡Department of Human Genetics, McGill University, Montreal, Québec; §§Department of Pathology, Health Sciences North, Sudbury, Ontario; ‖‖Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta; ¶¶Department of Pathology, The Ottawa Hospital and University of Ottawa, Ottawa, Ontario; ##Centre hospitalier de l'Universite de Montreal, Montreal, Québec; ***Department of Pathology, London Health Sciences Centre, London, Ontario; †††Department of Molecular Genetics, University of Toronto, Toronto, Ontario; ‡‡‡Department of Pathology, Harvard Medical School, Massachusetts General Hospital, Boston, MA; §§§Pfizer Oncology Canada, Kirkland, Québec; and ‖‖‖Institut Universitaire de Cardiologie et de Pneumologie de Québec (Hôpital Laval), Université Laval, Québec, Québec.

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http://dx.doi.org/10.1097/JTO.0000000000000239DOI Listing
September 2014

Endothelial-specific Notch blockade inhibits vascular function and tumor growth through an eNOS-dependent mechanism.

Cancer Res 2014 May 5;74(9):2402-11. Epub 2014 Mar 5.

Authors' Affiliations: Genome Sciences Centre; Integrative Oncology Program; Department of Pathology and Laboratory Medicine, British Columbia Cancer Agency; and Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://cancerres.aacrjournals.org/content/74/9/2402.full.pdf
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-4038DOI Listing
May 2014

A clinically validated diagnostic second-generation sequencing assay for detection of hereditary BRCA1 and BRCA2 mutations.

J Mol Diagn 2013 Nov 4;15(6):796-809. Epub 2013 Oct 4.

Cancer Genetics Laboratory, BC Cancer Agency, Vancouver, British Columbia, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.jmoldx.2013.07.004DOI Listing
November 2013

Notch activation augments nitric oxide/soluble guanylyl cyclase signaling in immortalized ovarian surface epithelial cells and ovarian cancer cells.

Cell Signal 2013 Dec 13;25(12):2780-7. Epub 2013 Sep 13.

Department of Oncology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1016/j.cellsig.2013.09.008DOI Listing
December 2013

SASH1 is a scaffold molecule in endothelial TLR4 signaling.

J Immunol 2013 Jul 17;191(2):892-901. Epub 2013 Jun 17.

Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, British Columbia V5Z 1L3, Canada.

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http://dx.doi.org/10.4049/jimmunol.1200583DOI Listing
July 2013

Notch activation promotes endothelial survival through a PI3K-Slug axis.

Microvasc Res 2013 Sep 3;89:80-5. Epub 2013 Jun 3.

Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, V5Z 1L3 BC, Canada.

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http://dx.doi.org/10.1016/j.mvr.2013.05.007DOI Listing
September 2013

Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.

N Engl J Med 2013 05 1;368(22):2059-74. Epub 2013 May 1.

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http://dx.doi.org/10.1056/NEJMoa1301689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767041PMC
May 2013

Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations.

Cancer Med 2012 Oct 18;1(2):105-13. Epub 2012 Jul 18.

Genome Sciences Centre, BC Cancer Agency Vancouver, BC, Canada; Department of Pathology and Laboratory Medicine, University of British Columbia Vancouver, BC, Canada.

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http://doi.wiley.com/10.1002/cam4.18
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http://dx.doi.org/10.1002/cam4.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544441PMC
October 2012

Notch-dependent regulation of the ischemic vasodilatory response--brief report.

Arterioscler Thromb Vasc Biol 2013 Mar 3;33(3):510-2. Epub 2013 Jan 3.

Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, V5Z 1L3, Canada.

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http://dx.doi.org/10.1161/ATVBAHA.112.300840DOI Listing
March 2013

Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development.

Cell Mol Life Sci 2013 Aug 16;70(16):2899-917. Epub 2012 Nov 16.

Terry Fox Laboratory, BC Cancer Agency, 675 West 10th Avenue, Vancouver, BC, Canada.

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http://link.springer.com/10.1007/s00018-012-1197-9
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http://dx.doi.org/10.1007/s00018-012-1197-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996658PMC
August 2013

T cells of patients with myelodysplastic syndrome are frequently derived from the malignant clone.

Br J Haematol 2012 Feb;156(3):409-12

Pathology and Laboratory Medicine of British Columbia Children's Hospital; Bristish Columbia Genome Sciences Centre, BC Cancer Agency; Pathology and Laboratory Medicine, University of British Columbia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191868PMC
http://dx.doi.org/10.1111/j.1365-2141.2011.08872.xDOI Listing
February 2012

Heterotrimeric Gi/Go proteins modulate endothelial TLR signaling independent of the MyD88-dependent pathway.

Am J Physiol Heart Circ Physiol 2011 Dec 23;301(6):H2246-53. Epub 2011 Sep 23.

Genome Sciences Centre, Vancouver, British Columbia, Canada.

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http://www.physiology.org/doi/10.1152/ajpheart.01194.2010
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http://dx.doi.org/10.1152/ajpheart.01194.2010DOI Listing
December 2011

Mouse models of myelodysplastic syndromes.

Leuk Res 2011 Jul 3;35(7):853-62. Epub 2011 Apr 3.

Genome Sciences Centre, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S014521261100123
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http://dx.doi.org/10.1016/j.leukres.2011.03.007DOI Listing
July 2011

RUNX3 maintains the mesenchymal phenotype after termination of the Notch signal.

J Biol Chem 2011 Apr 2;286(13):11803-13. Epub 2011 Feb 2.

British Columbia Cancer Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1074/jbc.M111.222331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064231PMC
April 2011

MicroRNA-146a disrupts hematopoietic differentiation and survival.

Exp Hematol 2011 Feb 7;39(2):167-178.e4. Epub 2010 Oct 7.

British Columbia Cancer Agency Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.exphem.2010.09.011DOI Listing
February 2011

Vascularization predicts overall survival and risk of transformation in follicular lymphoma.

Haematologica 2010 Dec 16;95(12):2157-60. Epub 2010 Aug 16.

Pathology, British Columbia Cancer Agency Center for Lymphoid Cancer, Vancouver, Canada.

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http://dx.doi.org/10.3324/haematol.2009.021766DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995576PMC
December 2010

Innate immune signaling in the myelodysplastic syndromes.

Hematol Oncol Clin North Am 2010 Apr;24(2):343-59

Genome Sciences Centre, British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S08898588100002
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http://dx.doi.org/10.1016/j.hoc.2010.02.008DOI Listing
April 2010

Deregulation of innate immune signaling in myelodysplastic syndromes is associated with deletion of chromosome arm 5q.

Cell Cycle 2010 Mar 11;9(5):855-6. Epub 2010 Mar 11.

Genome Sciences Centre and Department of Pathology and Laboratory Medicine, BC Cancer Agency, Vancouver, BC, Canada.

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http://www.tandfonline.com/doi/abs/10.4161/cc.9.5.11156
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http://dx.doi.org/10.4161/cc.9.5.11156DOI Listing
March 2010

Constitutively overexpressed 21 kDa protein in Hodgkin lymphoma and aggressive non-Hodgkin lymphomas identified as cytochrome B5b (CYB5B).

Mol Cancer 2010 Jan 26;9:14. Epub 2010 Jan 26.

Centre for Translational and Applied Genomics, British Columbia Cancer Agency, Provincial Health Services Authority Laboratories, 600 West 10th Avenue, Vancouver, British Columbia, V5Z 4E6, Canada.

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http://dx.doi.org/10.1186/1476-4598-9-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2829491PMC
January 2010

Involvement of endothelial progenitor cells in tumor vascularization.

Microvasc Res 2010 May 18;79(3):217-23. Epub 2010 Jan 18.

Pathology and Laboratory Medicine and Genome Sciences Centre, British Columbia Cancer Agency Research Centre, 675 West 10th Avenue, V5Z 1L3 British Columbia, Vancouver, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S002628621000008
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http://dx.doi.org/10.1016/j.mvr.2010.01.007DOI Listing
May 2010

Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal.

Physiol Genomics 2010 Feb 1;40(3):150-7. Epub 2009 Dec 1.

Terry Fox Laboratory, British Columbia Cancer Agency, Vancouver, British Columbia, Canada V5Z 1L3.

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http://dx.doi.org/10.1152/physiolgenomics.00142.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825764PMC
February 2010

Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.

Nat Med 2010 Jan 8;16(1):49-58. Epub 2009 Nov 8.

British Columbia Cancer Agency Research Centre, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/nm.2054DOI Listing
January 2010

Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells.

J Biol Chem 2009 Jul 27;284(29):19452-62. Epub 2009 May 27.

British Columbia Cancer Agency, University of British Columbia, Vancouver, British Columbia V5Z IL3, Canada.

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http://dx.doi.org/10.1074/jbc.M109.011833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2740571PMC
July 2009

Reduction in multi-lineage and erythroid progenitors distinguishes myelodysplastic syndromes from non-malignant cytopenias.

Leuk Res 2009 Dec 2;33(12):1636-42. Epub 2009 May 2.

Department of Pathology and Laboratory Medicine, Vancouver General Hospital, Vancouver, Canada.

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Source
http://linkinghub.elsevier.com/retrieve/pii/S014521260900142
Publisher Site
http://dx.doi.org/10.1016/j.leukres.2009.03.019DOI Listing
December 2009