Alvin T Kho

Alvin T Kho

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Alvin T Kho

Publications by authors named "Alvin T Kho"

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Pulmonary Neuroendocrine Cells Secrete γ-Aminobutyric Acid to Induce Goblet Cell Hyperplasia in Primate Models.

Am J Respir Cell Mol Biol 2019 06;60(6):687-694

6 Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1165/rcmb.2018-0179OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543741PMC
June 2019

Circulating microRNAs and prediction of asthma exacerbation in childhood asthma.

Respir Res 2018 06 26;19(1):128. Epub 2018 Jun 26.

Channing Division of Network Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s12931-018-0828-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020199PMC
June 2018

Circulating microRNAs and association with methacholine PC20 in the Childhood Asthma Management Program (CAMP) cohort.

PLoS One 2017 27;12(7):e0180329. Epub 2017 Jul 27.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180329PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531511PMC
October 2017

Asthma remission: Predicting future airways responsiveness using an miRNA network.

J Allergy Clin Immunol 2017 08 24;140(2):598-600.e8. Epub 2017 Feb 24.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2017.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546990PMC
August 2017

Circulating MicroRNAs: Association with Lung Function in Asthma.

PLoS One 2016 30;11(6):e0157998. Epub 2016 Jun 30.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157998PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928864PMC
July 2017

CRISPLD2 (LGL1) inhibits proinflammatory mediators in human fetal, adult, and COPD lung fibroblasts and epithelial cells.

Physiol Rep 2016 09;4(17)

Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada Departments of Human Genetics and Pediatrics, McGill University, Montreal, Quebec, Canada

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http://dx.doi.org/10.14814/phy2.12942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027350PMC
September 2016

Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures.

Mol Cell Proteomics 2016 06 1;15(6):1877-94. Epub 2016 Mar 1.

From the ‡Department of Medicine, Division of Infectious Diseases, Boston Children's Hospital and §Harvard Medical School, Boston, Massachusetts; Precision Vaccines Program, Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M115.055541
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http://dx.doi.org/10.1074/mcp.M115.055541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083103PMC
June 2016

Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures.

Mol Autism 2015 21;6:66. Epub 2015 Dec 21.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA USA ; Children's Hospital Informatics Program, Boston Children's Hospital, Boston, MA USA ; Department of Pediatrics, Harvard Medical School, Boston, MA USA.

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http://www.molecularautism.com/content/6/1/66
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http://dx.doi.org/10.1186/s13229-015-0061-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687343PMC
December 2015

The genomic origins of asthma.

Thorax 2014 May 25;69(5):481-7. Epub 2014 Mar 25.

Channing Division of Network Medicine, Brigham and Women's Hospital, , Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2014-205166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4343201PMC
May 2014

Identification of dedifferentiation and redevelopment phases during postpneumonectomy lung growth.

Am J Physiol Lung Cell Mol Physiol 2013 Oct 30;305(8):L542-54. Epub 2013 Aug 30.

Boston Children's Hospital, 320 Longwood Ave., Boston, MA 02115

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http://dx.doi.org/10.1152/ajplung.00403.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798774PMC
October 2013

Cell elasticity determines macrophage function.

PLoS One 2012 18;7(9):e41024. Epub 2012 Sep 18.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0041024PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445606PMC
March 2013

Maternal allergen exposure reprograms the developmental lung transcriptome in atopic and normoresponsive rat pups.

Am J Physiol Lung Cell Mol Physiol 2012 Nov 14;303(10):L899-911. Epub 2012 Sep 14.

Departments of Human Genetics, Montreal Children’s Hospital Research Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1152/ajplung.00179.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517678PMC
November 2012

Expression analysis of asthma candidate genes during human and murine lung development.

Respir Res 2011 Jun 23;12:86. Epub 2011 Jun 23.

Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/1465-9921-12-86DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141421PMC
June 2011

Isolation and transcriptome analysis of adult zebrafish cells enriched for skeletal muscle progenitors.

Muscle Nerve 2011 May 17;43(5):741-50. Epub 2011 Feb 17.

Howard Hughes Medical Institute, Center for Life Science, Room CLS15027.1, Children's Hospital Boston, 3 Blackfan Circle, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1002/mus.21972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075361PMC
May 2011

Proteomic temporal profile of human brain endothelium after oxidative stress.

Stroke 2011 Jan 16;42(1):37-43. Epub 2010 Dec 16.

Clinical Proteomics Research Center, Massachusetts General Hospital, Harvard Medial School, Boston, MA, USA.

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http://dx.doi.org/10.1161/STROKEAHA.110.585703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696517PMC
January 2011

Genetic influences on asthma susceptibility in the developing lung.

Am J Respir Cell Mol Biol 2010 Dec 29;43(6):720-30. Epub 2010 Jan 29.

Department of Human Genetics, McGill University, 4060 Saint Catherine West, Montreal, PQ, Canada.

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http://dx.doi.org/10.1165/rcmb.2009-0412OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159089PMC
December 2010

Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression.

J Cell Biol 2010 Aug;190(4):693-706

Molecular and Integrative Physiological Sciences, Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115.

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http://dx.doi.org/10.1083/jcb.201004082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928007PMC
August 2010

An EGFR autocrine loop encodes a slow-reacting but dominant mode of mechanotransduction in a polarized epithelium.

FASEB J 2010 May 7;24(5):1604-15. Epub 2010 Jan 7.

Division of Health Sciences and Technology, Harvard-Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1096/fj.09-145367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879944PMC
May 2010

Transcriptomic analysis of human lung development.

Am J Respir Crit Care Med 2010 Jan 8;181(1):54-63. Epub 2009 Oct 8.

Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1164/rccm.200907-1063OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797628PMC
January 2010

Transcriptional regulation differs in affected facioscapulohumeral muscular dystrophy patients compared to asymptomatic related carriers.

Proc Natl Acad Sci U S A 2009 Apr 1;106(15):6220-5. Epub 2009 Apr 1.

Human Genome Research Center, Department of Genetics and Evolutive Biology, Institute of Biosciences, University of São Paulo, 05508-090, São Paulo, Brazil.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0901573106
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http://dx.doi.org/10.1073/pnas.0901573106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664154PMC
April 2009

Expression profiles of the mouse lung identify a molecular signature of time-to-birth.

Am J Respir Cell Mol Biol 2009 Jan 29;40(1):47-57. Epub 2008 Jul 29.

Childrens Hospital Informatics Program, Children's Hospital Boston, Harvard-MIT Division of Health Sciences and Technology, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1165/rcmb.2008-0048OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2606946PMC
January 2009

Cerebellar 'transcriptome' reveals cell-type and stage-specific expression during postnatal development and tumorigenesis.

Mol Cell Neurosci 2006 Nov 8;33(3):247-59. Epub 2006 Sep 8.

Department of Pediatric Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.mcn.2006.07.010DOI Listing
November 2006

Melanoma cell adhesion molecule is a novel marker for human fetal myogenic cells and affects myoblast fusion.

J Cell Sci 2006 Aug 11;119(Pt 15):3117-27. Epub 2006 Jul 11.

Division of Genetics and Program in Genomics, Children's Hospital Boston, 320 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1242/jcs.03056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1578761PMC
August 2006

Mass spectrometry-based study of the plasma proteome in a mouse intestinal tumor model.

J Proteome Res 2006 Aug;5(8):1866-78

Gastrointestinal Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, 02114, USA.

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http://dx.doi.org/10.1021/pr060120rDOI Listing
August 2006

Predicting survival within the lung cancer histopathological hierarchy using a multi-scale genomic model of development.

PLoS Med 2006 Jul;3(7):e232

Children's Hospital Informatics Program, Children's Hospital Boston, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.0030232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1483910PMC
July 2006

Transcriptome-scale similarities between mouse and human skeletal muscles with normal and myopathic phenotypes.

BMC Musculoskelet Disord 2006 Mar 7;7:23. Epub 2006 Mar 7.

Children's Hospital Informatics Program, Harvard-MIT Division of Health Sciences and Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1186/1471-2474-7-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525166PMC
March 2006

Variations in gene expression among different types of human skeletal muscle.

Muscle Nerve 2005 Oct;32(4):483-91

Genomics Program, Enders 561, Howard Hughes Medical Institute and Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1002/mus.20356DOI Listing
October 2005

The influence of muscle type and dystrophin deficiency on murine expression profiles.

Mamm Genome 2005 Oct 29;16(10):739-48. Epub 2005 Oct 29.

Division of Genetics and Genomics Program, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1007/s00335-005-0053-8DOI Listing
October 2005

The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas.

J Neuropathol Exp Neurol 2004 May;63(5):499-509

Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/jnen/63.5.499DOI Listing
May 2004

Molecular classification of nemaline myopathies: "nontyping" specimens exhibit unique patterns of gene expression.

Neurobiol Dis 2004 Apr;15(3):590-600

Genomics Program and Divisison of Genetics, Children's Hospital Boston, and Harvard Medical School, MA 20115, USA.

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http://dx.doi.org/10.1016/j.nbd.2003.12.013DOI Listing
April 2004

Gene expression profiling of Duchenne muscular dystrophy skeletal muscle.

Neurogenetics 2003 Aug 16;4(4):163-71. Epub 2003 Apr 16.

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1007/s10048-003-0148-xDOI Listing
August 2003