Alvaro N A Monteiro

Alvaro N A Monteiro

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Alvaro N A Monteiro

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CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

Cell Death Discov 2019 19;5:105. Epub 2019 Jun 19.

1Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198 USA.

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http://dx.doi.org/10.1038/s41420-019-0185-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6584691PMC
June 2019

Germline Missense Variants in : New Trends and Challenges for Clinical Annotation.

Cancers (Basel) 2019 Apr 12;11(4). Epub 2019 Apr 12.

Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

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https://www.mdpi.com/2072-6694/11/4/522
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http://dx.doi.org/10.3390/cancers11040522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520942PMC
April 2019

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility.

Authors:
Madalene Earp Jonathan P Tyrer Stacey J Winham Hui-Yi Lin Ganna Chornokur Joe Dennis Katja K H Aben Hoda Anton-Culver Natalia Antonenkova Elisa V Bandera Yukie T Bean Matthias W Beckmann Line Bjorge Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Fiona Bruinsma Clareann H Bunker Ralf Butzow Ian G Campbell Karen Carty Jenny Chang-Claude Linda S Cook Daniel W Cramer Julie M Cunningham Cezary Cybulski Agnieszka Dansonka-Mieszkowska Evelyn Despierre Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Douglas F Easton Diana M Eccles Robert P Edwards Arif B Ekici Peter A Fasching Brooke L Fridley Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Marc T Goodman Jacek Gronwald Philipp Harter Alexander Hein Florian Heitz Michelle A T Hildebrandt Peter Hillemanns Claus K Hogdall Estrid Høgdall Satoyo Hosono Edwin S Iversen Anna Jakubowska Allan Jensen Bu-Tian Ji Audrey Y Jung Beth Y Karlan Melissa Kellar Lambertus A Kiemeney Boon Kiong Lim Susanne K Kjaer Camilla Krakstad Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Shashi Lele Jenny Lester Douglas A Levine Zheng Li Dong Liang Jolanta Lissowska Karen Lu Jan Lubinski Lene Lundvall Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Iain McNeish Usha Menon Roger L Milne Francesmary Modugno Kirsten B Moysich Roberta B Ness Heli Nevanlinna Kunle Odunsi Sara H Olson Irene Orlow Sandra Orsulic James Paul Tanja Pejovic Liisa M Pelttari Jenny B Permuth Malcolm C Pike Elizabeth M Poole Barry Rosen Mary Anne Rossing Joseph H Rothstein Ingo B Runnebaum Iwona K Rzepecka Eva Schernhammer Ira Schwaab Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Weiva Sieh Honglin Song Melissa C Southey Beata Spiewankiewicz Lara Sucheston-Campbell Ingvild L Tangen Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Lotte Thomsen Shelley S Tworoger Anne M van Altena Ignace Vergote Liv Cecilie Vestrheim Thomsen Robert A Vierkant Christine S Walsh Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Yin-Ling Woo Anna H Wu Xifeng Wu Yong-Bing Xiang Hannah Yang Wei Zheng Argyrios Ziogas Alice W Lee Celeste L Pearce Andrew Berchuck Joellen M Schildkraut Susan J Ramus Alvaro N A Monteiro Steven A Narod Thomas A Sellers Simon A Gayther Linda E Kelemen Georgia Chenevix-Trench Harvey A Risch Paul D P Pharoah Ellen L Goode Catherine M Phelan

PLoS One 2018 6;13(7):e0197561. Epub 2018 Jul 6.

Division of Population Sciences, Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197561PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034790PMC
December 2018

Mutational heterogeneity in non-serous ovarian cancers.

Sci Rep 2017 08 29;7(1):9728. Epub 2017 Aug 29.

Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1038/s41598-017-10432-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574976PMC
August 2017

Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity.

ACS Chem Biol 2017 07 7;12(7):1883-1892. Epub 2017 Jun 7.

Drug Discovery Department, H. Lee Moffitt Cancer Center & Research Institute , Tampa, Florida 33612, United States.

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http://dx.doi.org/10.1021/acschembio.7b00147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551971PMC
July 2017

Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.

Authors:
Hermela Shimelis Romy L S Mesman Catharina Von Nicolai Asa Ehlen Lucia Guidugli Charlotte Martin Fabienne M G R Calléja Huong Meeks Emily Hallberg Jamie Hinton Jenna Lilyquist Chunling Hu Cora M Aalfs Kristiina Aittomäki Irene Andrulis Hoda Anton-Culver Volker Arndt Matthias W Beckmann Javier Benitez Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Anne-Lise Borresen-Dale Hiltrud Brauch Paul Brennan Hermann Brenner Annegien Broeks Barbara Brouwers Thomas Brüning Barbara Burwinkel Jenny Chang-Claude Georgia Chenevix-Trench Ching-Yu Cheng Ji-Yeob Choi J Margriet Collée Angela Cox Simon S Cross Kamila Czene Hatef Darabi Joe Dennis Thilo Dörk Isabel Dos-Santos-Silva Alison M Dunning Peter A Fasching Jonine Figueroa Henrik Flyger Montserrat García-Closas Graham G Giles Gord Glendon Pascal Guénel Christopher A Haiman Per Hall Ute Hamann Mikael Hartman Frans B Hogervorst Antoinette Hollestelle John L Hopper Hidemi Ito Anna Jakubowska Daehee Kang Veli-Matti Kosma Vessela Kristensen Kah-Nyin Lai Diether Lambrechts Loic Le Marchand Jingmei Li Annika Lindblom Artitaya Lophatananon Jan Lubinski Eva Machackova Arto Mannermaa Sara Margolin Frederik Marme Keitaro Matsuo Hui Miao Kyriaki Michailidou Roger L Milne Kenneth Muir Susan L Neuhausen Heli Nevanlinna Janet E Olson Curtis Olswold Jan J C Oosterwijk Ana Osorio Paolo Peterlongo Julian Peto Paul D P Pharoah Katri Pylkäs Paolo Radice Muhammad Usman Rashid Valerie Rhenius Anja Rudolph Suleeporn Sangrajrang Elinor J Sawyer Marjanka K Schmidt Minouk J Schoemaker Caroline Seynaeve Mitul Shah Chen-Yang Shen Martha Shrubsole Xiao-Ou Shu Susan Slager Melissa C Southey Daniel O Stram Anthony Swerdlow Soo H Teo Ian Tomlinson Diana Torres Thérèse Truong Christi J van Asperen Lizet E van der Kolk Qin Wang Robert Winqvist Anna H Wu Jyh-Cherng Yu Wei Zheng Ying Zheng Jennifer Leary Logan Walker Lenka Foretova Florentia Fostira Kathleen B M Claes Liliana Varesco Setareh Moghadasi Douglas F Easton Amanda Spurdle Peter Devilee Harry Vrieling Alvaro N A Monteiro David E Goldgar Aura Carreira Maaike P G Vreeswijk Fergus J Couch

Cancer Res 2017 06 10;77(11):2789-2799. Epub 2017 Mar 10.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508554PMC
June 2017

Dissecting genetic risk factors in breast cancer.

Oncotarget 2017 Feb;8(8):12540-12541

Department of Cell Biology, Microbiology, and Molecular Biology, Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, College of Arts and Sciences, University of South Florida, Tampa, FL, USA.

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http://dx.doi.org/10.18632/oncotarget.15089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355027PMC
February 2017

What can yeast tell us about breast cancer?

Cell Cycle 2017 01 22;16(2):157-158. Epub 2016 Dec 22.

a Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute , Tampa , FL , USA.

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http://dx.doi.org/10.1080/15384101.2016.1230376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283815PMC
January 2017

Response.

J Natl Cancer Inst 2016 12 31;108(12). Epub 2016 Aug 31.

Molecular Cancer Epidemiology Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia (ABS); Basser Center, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, PA (SD); Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY (MR); Department of Medicine (SB) and Department of Dermatology (DEG), Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, UT; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy (PR); Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC (Instituto de Investigacion Sanitaria del Hospital Clinico San Carlos), Madrid, Spain (MdlH); Department of Human Genetics and Department of Cancer Epidemiology, Leiden University Medical Center, Leiden, the Netherlands (PD); Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL (ANAM); Department of Pathology, the University of Melbourne, Melbourne, Victoria, Australia (MS); Faculty of Medicine, University of Southampton, Southampton, UK (DE); Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN (FJC).

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http://dx.doi.org/10.1093/jnci/djw173DOI Listing
December 2016

Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration.

Authors:
Jennifer B Permuth Brett Reid Madalene Earp Y Ann Chen Alvaro N A Monteiro Zhihua Chen Georgia Chenevix-Trench Peter A Fasching Matthias W Beckmann Diether Lambrechts Adriaan Vanderstichele Els Van Niewenhuyse Ignace Vergote Mary Anne Rossing Jennifer Anne Doherty Jenny Chang-Claude Kirsten Moysich Kunle Odunsi Marc T Goodman Yurii B Shvetsov Lynne R Wilkens Pamela J Thompson Thilo Dörk Natalia Bogdanova Ralf Butzow Heli Nevanlinna Liisa Pelttari Arto Leminen Francesmary Modugno Robert P Edwards Roberta B Ness Joseph Kelley Florian Heitz Beth Karlan Jenny Lester Susanne K Kjaer Allan Jensen Graham Giles Michelle Hildebrandt Dong Liang Karen H Lu Xifeng Wu Douglas A Levine Maria Bisogna Andrew Berchuck Daniel W Cramer Kathryn L Terry Shelley S Tworoger Elizabeth M Poole Elisa V Bandera Brooke Fridley Julie Cunningham Stacey J Winham Sara H Olson Irene Orlow Line Bjorge Lambertus A Kiemeney Leon Massuger Tanja Pejovic Melissa Moffitt Nhu Le Linda S Cook Angela Brooks-Wilson Linda E Kelemen Jacek Gronwald Jan Lubinski Nicolas Wentzensen Louise A Brinton Jolanta Lissowska Hanna Yang Estrid Hogdall Claus Hogdall Lene Lundvall Paul D P Pharoah Honglin Song Ian Campbell Diana Eccles Iain McNeish Alice Whittemore Valerie McGuire Weiva Sieh Joseph Rothstein Catherine M Phelan Harvey Risch Steven Narod John McLaughlin Hoda Anton-Culver Argyrios Ziogas Usha Menon Simon Gayther Susan J Ramus Aleksandra Gentry-Maharaj Celeste Leigh Pearce Anna H Wu Jolanta Kupryjanczyk Agnieszka Dansonka-Mieszkowska Joellen M Schildkraut Jin Q Cheng Ellen L Goode Thomas A Sellers

Oncotarget 2016 11;7(45):72381-72394

Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL, USA.

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http://dx.doi.org/10.18632/oncotarget.10546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340123PMC
November 2016

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk.

Authors:
Ganna Chornokur Hui-Yi Lin Jonathan P Tyrer Kate Lawrenson Joe Dennis Ernest K Amankwah Xiaotao Qu Ya-Yu Tsai Heather S L Jim Zhihua Chen Ann Y Chen Jennifer Permuth-Wey Katja K H Aben Hoda Anton-Culver Natalia Antonenkova Fiona Bruinsma Elisa V Bandera Yukie T Bean Matthias W Beckmann Maria Bisogna Line Bjorge Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Clareann H Bunker Ralf Butzow Ian G Campbell Karen Carty Jenny Chang-Claude Linda S Cook Daniel W Cramer Julie M Cunningham Cezary Cybulski Agnieszka Dansonka-Mieszkowska Andreas du Bois Evelyn Despierre Ed Dicks Jennifer A Doherty Thilo Dörk Matthias Dürst Douglas F Easton Diana M Eccles Robert P Edwards Arif B Ekici Peter A Fasching Brooke L Fridley Yu-Tang Gao Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Marc T Goodman Jacek Gronwald Patricia Harrington Philipp Harter Alexander Hein Florian Heitz Michelle A T Hildebrandt Peter Hillemanns Claus K Hogdall Estrid Hogdall Satoyo Hosono Anna Jakubowska Allan Jensen Bu-Tian Ji Beth Y Karlan Linda E Kelemen Mellissa Kellar Lambertus A Kiemeney Camilla Krakstad Susanne K Kjaer Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Alice W Lee Shashi Lele Arto Leminen Jenny Lester Douglas A Levine Dong Liang Boon Kiong Lim Jolanta Lissowska Karen Lu Jan Lubinski Lene Lundvall Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Iain McNeish Usha Menon Roger L Milne Francesmary Modugno Kirsten B Moysich Roberta B Ness Heli Nevanlinna Ursula Eilber Kunle Odunsi Sara H Olson Irene Orlow Sandra Orsulic Rachel Palmieri Weber James Paul Celeste L Pearce Tanja Pejovic Liisa M Pelttari Malcolm C Pike Elizabeth M Poole Harvey A Risch Barry Rosen Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Eva Schernhammer Ira Schwaab Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Weiva Sieh Honglin Song Melissa C Southey Beata Spiewankiewicz Lara Sucheston Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Lotte Thomsen Ingvild L Tangen Shelley S Tworoger Anne M van Altena Robert A Vierkant Ignace Vergote Christine S Walsh Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Anna H Wu Xifeng Wu Yin-Ling Woo Hannah Yang Wei Zheng Argyrios Ziogas Hanis N Hasmad Andrew Berchuck Edwin S Iversen Joellen M Schildkraut Susan J Ramus Ellen L Goode Alvaro N A Monteiro Simon A Gayther Steven A Narod Paul D P Pharoah Thomas A Sellers Catherine M Phelan

PLoS One 2015 19;10(6):e0128106. Epub 2015 Jun 19.

Division of Population Sciences, Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, United States of America.

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http://eprints.soton.ac.uk/382464/1/__userfiles.soton.ac.uk_
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http://dx.plos.org/10.1371/journal.pone.0128106
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0128106PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474865PMC
April 2016

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers.

Authors:
Huong D Meeks Honglin Song Kyriaki Michailidou Manjeet K Bolla Joe Dennis Qin Wang Daniel Barrowdale Debra Frost Lesley McGuffog Steve Ellis Bingjian Feng Saundra S Buys John L Hopper Melissa C Southey Andrea Tesoriero Paul A James Fiona Bruinsma Ian G Campbell Annegien Broeks Marjanka K Schmidt Frans B L Hogervorst Matthias W Beckman Peter A Fasching Olivia Fletcher Nichola Johnson Elinor J Sawyer Elio Riboli Susana Banerjee Usha Menon Ian Tomlinson Barbara Burwinkel Ute Hamann Frederik Marme Anja Rudolph Ramunas Janavicius Laima Tihomirova Nadine Tung Judy Garber Daniel Cramer Kathryn L Terry Elizabeth M Poole Shelley S Tworoger Cecilia M Dorfling Elizabeth J van Rensburg Andrew K Godwin Pascal Guénel Thérèse Truong Dominique Stoppa-Lyonnet Francesca Damiola Sylvie Mazoyer Olga M Sinilnikova Claudine Isaacs Christine Maugard Stig E Bojesen Henrik Flyger Anne-Marie Gerdes Thomas V O Hansen Allen Jensen Susanne K Kjaer Claus Hogdall Estrid Hogdall Inge Sokilde Pedersen Mads Thomassen Javier Benitez Anna González-Neira Ana Osorio Miguel de la Hoya Pedro Perez Segura Orland Diez Conxi Lazaro Joan Brunet Hoda Anton-Culver Lee Eunjung Esther M John Susan L Neuhausen Yuan Chun Ding Danielle Castillo Jeffrey N Weitzel Patricia A Ganz Robert L Nussbaum Salina B Chan Beth Y Karlan Jenny Lester Anna Wu Simon Gayther Susan J Ramus Weiva Sieh Alice S Whittermore Alvaro N A Monteiro Catherine M Phelan Mary Beth Terry Marion Piedmonte Kenneth Offit Mark Robson Douglas Levine Kirsten B Moysich Rikki Cannioto Sara H Olson Mary B Daly Katherine L Nathanson Susan M Domchek Karen H Lu Dong Liang Michelle A T Hildebrant Roberta Ness Francesmary Modugno Leigh Pearce Marc T Goodman Pamela J Thompson Hermann Brenner Katja Butterbach Alfons Meindl Eric Hahnen Barbara Wappenschmidt Hiltrud Brauch Thomas Brüning Carl Blomqvist Sofia Khan Heli Nevanlinna Liisa M Pelttari Kristiina Aittomäki Ralf Butzow Natalia V Bogdanova Thilo Dörk Annika Lindblom Sara Margolin Johanna Rantala Veli-Matti Kosma Arto Mannermaa Diether Lambrechts Patrick Neven Kathleen B M Claes Tom Van Maerken Jenny Chang-Claude Dieter Flesch-Janys Florian Heitz Raymonda Varon-Mateeva Paolo Peterlongo Paolo Radice Alessandra Viel Monica Barile Bernard Peissel Siranoush Manoukian Marco Montagna Cristina Oliani Ana Peixoto Manuel R Teixeira Anita Collavoli Emily Hallberg Janet E Olson Ellen L Goode Steven N Hart Hermela Shimelis Julie M Cunningham Graham G Giles Roger L Milne Sue Healey Kathy Tucker Christopher A Haiman Brian E Henderson Mark S Goldberg Marc Tischkowitz Jacques Simard Penny Soucy Diana M Eccles Nhu Le Anne-Lise Borresen-Dale Vessela Kristensen Helga B Salvesen Line Bjorge Elisa V Bandera Harvey Risch Wei Zheng Alicia Beeghly-Fadiel Hui Cai Katri Pylkäs Robert A E M Tollenaar Ans M W van der Ouweland Irene L Andrulis Julia A Knight Steven Narod Peter Devilee Robert Winqvist Jonine Figueroa Mark H Greene Phuong L Mai Jennifer T Loud Montserrat García-Closas Minouk J Schoemaker Kamila Czene Hatef Darabi Iain McNeish Nadeem Siddiquil Rosalind Glasspool Ava Kwong Sue K Park Soo Hwang Teo Sook-Yee Yoon Keitaro Matsuo Satoyo Hosono Yin Ling Woo Yu-Tang Gao Lenka Foretova Christian F Singer Christine Rappaport-Feurhauser Eitan Friedman Yael Laitman Gad Rennert Evgeny N Imyanitov Peter J Hulick Olufunmilayo I Olopade Leigha Senter Edith Olah Jennifer A Doherty Joellen Schildkraut Linetta B Koppert Lambertus A Kiemeney Leon F A G Massuger Linda S Cook Tanja Pejovic Jingmei Li Ake Borg Anna Öfverholm Mary Anne Rossing Nicolas Wentzensen Karin Henriksson Angela Cox Simon S Cross Barbara J Pasini Mitul Shah Maria Kabisch Diana Torres Anna Jakubowska Jan Lubinski Jacek Gronwald Bjarni A Agnarsson Jolanta Kupryjanczyk Joanna Moes-Sosnowska Florentia Fostira Irene Konstantopoulou Susan Slager Michael Jones Antonis C Antoniou Andrew Berchuck Anthony Swerdlow Georgia Chenevix-Trench Alison M Dunning Paul D P Pharoah Per Hall Douglas F Easton Fergus J Couch Amanda B Spurdle David E Goldgar

Enhancer scanning to locate regulatory regions in genomic loci.

Nat Protoc 2016 Jan 10;11(1):46-60. Epub 2015 Dec 10.

Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.

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http://dx.doi.org/10.1038/nprot.2015.136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756653PMC
January 2016

A high frequency of BRCA mutations in young black women with breast cancer residing in Florida.

Cancer 2015 Dec 19;121(23):4173-80. Epub 2015 Aug 19.

Division of Population Sciences, Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida.

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http://dx.doi.org/10.1002/cncr.29645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666784PMC
December 2015

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk.

Authors:
Ernest K Amankwah Hui-Yi Lin Jonathan P Tyrer Kate Lawrenson Joe Dennis Ganna Chornokur Katja K H Aben Hoda Anton-Culver Natalia Antonenkova Fiona Bruinsma Elisa V Bandera Yukie T Bean Matthias W Beckmann Maria Bisogna Line Bjorge Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Clareann H Bunker Ralf Butzow Ian G Campbell Karen Carty Zhihua Chen Y Ann Chen Jenny Chang-Claude Linda S Cook Daniel W Cramer Julie M Cunningham Cezary Cybulski Agnieszka Dansonka-Mieszkowska Andreas du Bois Evelyn Despierre Ed Dicks Jennifer A Doherty Thilo Dörk Matthias Dürst Douglas F Easton Diana M Eccles Robert P Edwards Arif B Ekici Peter A Fasching Brooke L Fridley Yu-Tang Gao Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Marc T Goodman Jacek Gronwald Patricia Harrington Philipp Harter Hanis N Hasmad Alexander Hein Florian Heitz Michelle A T Hildebrandt Peter Hillemanns Claus K Hogdall Estrid Hogdall Satoyo Hosono Edwin S Iversen Anna Jakubowska Allan Jensen Bu-Tian Ji Beth Y Karlan Heather Jim Melissa Kellar Lambertus A Kiemeney Camilla Krakstad Susanne K Kjaer Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Alice W Lee Shashi Lele Arto Leminen Jenny Lester Douglas A Levine Dong Liang Boon Kiong Lim Jolanta Lissowska Karen Lu Jan Lubinski Lene Lundvall Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Ian McNeish Usha Menon Roger L Milne Francesmary Modugno Kirsten B Moysich Roberta B Ness Heli Nevanlinna Ursula Eilber Kunle Odunsi Sara H Olson Irene Orlow Sandra Orsulic Rachel Palmieri Weber James Paul Celeste L Pearce Tanja Pejovic Liisa M Pelttari Jennifer Permuth-Wey Malcolm C Pike Elizabeth M Poole Harvey A Risch Barry Rosen Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Eva Schernhammer Ira Schwaab Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Weiva Sieh Honglin Song Melissa C Southey Beata Spiewankiewicz Lara Sucheston-Campbell Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Lotte Thomsen Ingvild L Tangen Shelley S Tworoger Anne M van Altena Robert A Vierkant Ignace Vergote Christine S Walsh Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Anna H Wu Xifeng Wu Yin-Ling Woo Hannah Yang Wei Zheng Argyrios Ziogas Linda E Kelemen Andrew Berchuck Joellen M Schildkraut Susan J Ramus Ellen L Goode Alvaro N A Monteiro Simon A Gayther Steven A Narod Paul D P Pharoah Thomas A Sellers Catherine M Phelan

Genet Epidemiol 2015 Dec 24;39(8):689-97. Epub 2015 Sep 24.

Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, United States of America.

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http://dx.doi.org/10.1002/gepi.21921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4721602PMC
December 2015

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer.

Authors:
Kate Lawrenson Edwin S Iversen Jonathan Tyrer Rachel Palmieri Weber Patrick Concannon Dennis J Hazelett Qiyuan Li Jeffrey R Marks Andrew Berchuck Janet M Lee Katja K H Aben Hoda Anton-Culver Natalia Antonenkova Elisa V Bandera Yukie Bean Matthias W Beckmann Maria Bisogna Line Bjorge Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Fiona Bruinsma Ralf Butzow Ian G Campbell Karen Carty Jenny Chang-Claude Georgia Chenevix-Trench Ann Chen Zhihua Chen Linda S Cook Daniel W Cramer Julie M Cunningham Cezary Cybulski Joanna Plisiecka-Halasa Joe Dennis Ed Dicks Jennifer A Doherty Thilo Dörk Andreas du Bois Diana Eccles Douglas T Easton Robert P Edwards Ursula Eilber Arif B Ekici Peter A Fasching Brooke L Fridley Yu-Tang Gao Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Ellen L Goode Marc T Goodman Jacek Gronwald Philipp Harter Hanis Nazihah Hasmad Alexander Hein Florian Heitz Michelle A T Hildebrandt Peter Hillemanns Estrid Hogdall Claus Hogdall Satoyo Hosono Anna Jakubowska James Paul Allan Jensen Beth Y Karlan Susanne Kruger Kjaer Linda E Kelemen Melissa Kellar Joseph L Kelley Lambertus A Kiemeney Camilla Krakstad Diether Lambrechts Sandrina Lambrechts Nhu D Le Alice W Lee Rikki Cannioto Arto Leminen Jenny Lester Douglas A Levine Dong Liang Jolanta Lissowska Karen Lu Jan Lubinski Lene Lundvall Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Heli Nevanlinna Iain McNeish Usha Menon Francesmary Modugno Kirsten B Moysich Steven A Narod Lotte Nedergaard Roberta B Ness Mat Adenan Noor Azmi Kunle Odunsi Sara H Olson Irene Orlow Sandra Orsulic Celeste L Pearce Tanja Pejovic Liisa M Pelttari Jennifer Permuth-Wey Catherine M Phelan Malcolm C Pike Elizabeth M Poole Susan J Ramus Harvey A Risch Barry Rosen Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Agnieszka Budzilowska Thomas A Sellers Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Weiva Sieh Honglin Song Melissa C Southey Lara Sucheston Ingvild L Tangen Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Agnieszka Timorek Shelley S Tworoger Els Van Nieuwenhuysen Ignace Vergote Robert A Vierkant Shan Wang-Gohrke Christine Walsh Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Yin-Ling Woo Xifeng Wu Anna H Wu Hannah Yang Wei Zheng Argyrios Ziogas Gerhard A Coetzee Matthew L Freedman Alvaro N A Monteiro Joanna Moes-Sosnowska Jolanta Kupryjanczyk Paul D Pharoah Simon A Gayther Joellen M Schildkraut

Carcinogenesis 2015 Nov 29;36(11):1341-53. Epub 2015 Sep 29.

Department of Community and Family Medicine, Duke University Medical Center, Durham, NC 27710, USA, Cancer Control and Population Sciences, Duke Cancer Institute, Durham, NC 27710, USA,

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http://dx.doi.org/10.1093/carcin/bgv138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635670PMC
November 2015

Functional analysis of the 11q23.3 glioma susceptibility locus implicates PHLDB1 and DDX6 in glioma susceptibility.

Sci Rep 2015 Nov 27;5:17367. Epub 2015 Nov 27.

Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

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http://dx.doi.org/10.1038/srep17367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661592PMC
November 2015

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk.

Authors:
Siddhartha P Kar Jonathan P Tyrer Qiyuan Li Kate Lawrenson Katja K H Aben Hoda Anton-Culver Natalia Antonenkova Georgia Chenevix-Trench Helen Baker Elisa V Bandera Yukie T Bean Matthias W Beckmann Andrew Berchuck Maria Bisogna Line Bjørge Natalia Bogdanova Louise Brinton Angela Brooks-Wilson Ralf Butzow Ian Campbell Karen Carty Jenny Chang-Claude Yian Ann Chen Zhihua Chen Linda S Cook Daniel Cramer Julie M Cunningham Cezary Cybulski Agnieszka Dansonka-Mieszkowska Joe Dennis Ed Dicks Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Diana Eccles Douglas F Easton Robert P Edwards Arif B Ekici Peter A Fasching Brooke L Fridley Yu-Tang Gao Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Ellen L Goode Marc T Goodman Jacek Grownwald Patricia Harrington Philipp Harter Alexander Hein Florian Heitz Michelle A T Hildebrandt Peter Hillemanns Estrid Hogdall Claus K Hogdall Satoyo Hosono Edwin S Iversen Anna Jakubowska James Paul Allan Jensen Bu-Tian Ji Beth Y Karlan Susanne K Kjaer Linda E Kelemen Melissa Kellar Joseph Kelley Lambertus A Kiemeney Camilla Krakstad Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Alice W Lee Shashi Lele Arto Leminen Jenny Lester Douglas A Levine Dong Liang Jolanta Lissowska Karen Lu Jan Lubinski Lene Lundvall Leon Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Iain A McNeish Usha Menon Francesmary Modugno Kirsten B Moysich Steven A Narod Lotte Nedergaard Roberta B Ness Heli Nevanlinna Kunle Odunsi Sara H Olson Irene Orlow Sandra Orsulic Rachel Palmieri Weber Celeste Leigh Pearce Tanja Pejovic Liisa M Pelttari Jennifer Permuth-Wey Catherine M Phelan Malcolm C Pike Elizabeth M Poole Susan J Ramus Harvey A Risch Barry Rosen Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Joellen M Schildkraut Ira Schwaab Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Weiva Sieh Honglin Song Melissa C Southey Lara E Sucheston-Campbell Ingvild L Tangen Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Agnieszka Timorek Ya-Yu Tsai Shelley S Tworoger Anne M van Altena Els Van Nieuwenhuysen Ignace Vergote Robert A Vierkant Shan Wang-Gohrke Christine Walsh Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Yin-Ling Woo Xifeng Wu Anna Wu Hannah Yang Wei Zheng Argyrios Ziogas Thomas A Sellers Alvaro N A Monteiro Matthew L Freedman Simon A Gayther Paul D P Pharoah

Cancer Epidemiol Biomarkers Prev 2015 Oct 24;24(10):1574-84. Epub 2015 Jul 24.

Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom. Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-1270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592449PMC
October 2015

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study.

Hum Mol Genet 2015 Sep 2;24(18):5356-66. Epub 2015 Jul 2.

Department of Public Health Sciences, Center for Cancer Epidemiology and Prevention, Department of Human Genetics, The University of Chicago, Chicago, IL, USA,

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https://www.repository.cam.ac.uk/bitstream/handle/1810/24890
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http://hmg.oxfordjournals.org/content/early/2015/07/24/hmg.d
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http://www.hmg.oxfordjournals.org/lookup/doi/10.1093/hmg/ddv
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http://dx.doi.org/10.1093/hmg/ddv252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550826PMC
September 2015

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

Authors:
Heather S L Jim Hui-Yi Lin Jonathan P Tyrer Kate Lawrenson Joe Dennis Ganna Chornokur Zhihua Chen Ann Y Chen Jennifer Permuth-Wey Katja Kh Aben Hoda Anton-Culver Natalia Antonenkova Fiona Bruinsma Elisa V Bandera Yukie T Bean Matthias W Beckmann Maria Bisogna Line Bjorge Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Clareann H Bunker Ralf Butzow Ian G Campbell Karen Carty Jenny Chang-Claude Linda S Cook Daniel W Cramer Julie M Cunningham Cezary Cybulski Agnieszka Dansonka-Mieszkowska Andreas du Bois Evelyn Despierre Weiva Sieh Jennifer A Doherty Thilo Dörk Matthias Dürst Douglas F Easton Diana M Eccles Robert P Edwards Arif B Ekici Peter A Fasching Brooke L Fridley Yu-Tang Gao Aleksandra Gentry-Maharaj Graham G Giles Rosalind Glasspool Marc T Goodman Jacek Gronwald Philipp Harter Hanis N Hasmad Alexander Hein Florian Heitz Michelle A T Hildebrandt Peter Hillemanns Claus K Hogdall Estrid Hogdall Satoyo Hosono Edwin S Iversen Anna Jakubowska Allan Jensen Bu-Tian Ji Beth Y Karlan Melissa Kellar Lambertus A Kiemeney Camilla Krakstad Susanne K Kjaer Jolanta Kupryjanczyk Robert A Vierkant Diether Lambrechts Sandrina Lambrechts Nhu D Le Alice W Lee Shashi Lele Arto Leminen Jenny Lester Douglas A Levine Dong Liang Boon Kiong Lim Jolanta Lissowska Karen Lu Jan Lubinski Lene Lundvall Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Ian McNeish Usha Menon Roger L Milne Francesmary Modugno Lotte Thomsen Kirsten B Moysich Roberta B Ness Heli Nevanlinna Ursula Eilber Kunle Odunsi Sara H Olson Irene Orlow Sandra Orsulic Rachel Palmieri Weber James Paul Celeste L Pearce Tanja Pejovic Liisa M Pelttari Malcolm C Pike Elizabeth M Poole Eva Schernhammer Harvey A Risch Barry Rosen Mary Anne Rossing Joseph H Rothstein Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Ira Schwaab Xiao-Ou Shu Yurii B Shvetsov Nadeem Siddiqui Honglin Song Melissa C Southey Beata Spiewankiewicz Lara Sucheston-Campbell Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Ingvild L Tangen Shelley S Tworoger Anne M van Altena Ignace Vergote Christine S Walsh Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Kristine G Wicklund Lynne R Wilkens Anna H Wu Xifeng Wu Yin-Ling Woo Hannah Yang Wei Zheng Argyrios Ziogas Ernest Amankwah Andrew Berchuck Joellen M Schildkraut Linda E Kelemen Susan J Ramus Alvaro N A Monteiro Ellen L Goode Steven A Narod Simon A Gayther Paul D P Pharoah Thomas A Sellers Catherine M Phelan

J Genet Genome Res 2015;2(2). Epub 2015 Sep 15.

Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722961PMC
September 2015

Incorporating computational resources in a cancer research program.

Hum Genet 2015 May 17;134(5):467-78. Epub 2014 Oct 17.

Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL, 33612, USA.

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http://dx.doi.org/10.1007/s00439-014-1496-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401625PMC
May 2015

Probing structure-function relationships in missense variants in the carboxy-terminal region of BRCA1.

PLoS One 2014 20;9(5):e97766. Epub 2014 May 20.

Programa de Farmacologia, Instituto Nacional de Câncer, Rio de Janeiro, RJ, Brazil; Instituto Federal de Educação, Ciência e Tecnologia do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4028255PMC
January 2015

Functional annotation signatures of disease susceptibility loci improve SNP association analysis.

BMC Genomics 2014 May 24;15:398. Epub 2014 May 24.

Department of Statistical Science, Duke University, Box 90251, 27708-0251 Durham, NC, USA.

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http://dx.doi.org/10.1186/1471-2164-15-398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041996PMC
May 2014

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

Authors:
Jennifer Permuth-Wey Kate Lawrenson Howard C Shen Aneliya Velkova Jonathan P Tyrer Zhihua Chen Hui-Yi Lin Y Ann Chen Ya-Yu Tsai Xiaotao Qu Susan J Ramus Rod Karevan Janet Lee Nathan Lee Melissa C Larson Katja K Aben Hoda Anton-Culver Natalia Antonenkova Antonis C Antoniou Sebastian M Armasu François Bacot Laura Baglietto Elisa V Bandera Jill Barnholtz-Sloan Matthias W Beckmann Michael J Birrer Greg Bloom Natalia Bogdanova Louise A Brinton Angela Brooks-Wilson Robert Brown Ralf Butzow Qiuyin Cai Ian Campbell Jenny Chang-Claude Stephen Chanock Georgia Chenevix-Trench Jin Q Cheng Mine S Cicek Gerhard A Coetzee Linda S Cook Fergus J Couch Daniel W Cramer Julie M Cunningham Agnieszka Dansonka-Mieszkowska Evelyn Despierre Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Douglas F Easton Diana Eccles Robert Edwards Arif B Ekici Peter A Fasching David A Fenstermacher James M Flanagan Montserrat Garcia-Closas Aleksandra Gentry-Maharaj Graham G Giles Rosalind M Glasspool Jesus Gonzalez-Bosquet Marc T Goodman Martin Gore Bohdan Górski Jacek Gronwald Per Hall Mari K Halle Philipp Harter Florian Heitz Peter Hillemanns Maureen Hoatlin Claus K Høgdall Estrid Høgdall Satoyo Hosono Anna Jakubowska Allan Jensen Heather Jim Kimberly R Kalli Beth Y Karlan Stanley B Kaye Linda E Kelemen Lambertus A Kiemeney Fumitaka Kikkawa Gottfried E Konecny Camilla Krakstad Susanne Krüger Kjaer Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Johnathan M Lancaster Nhu D Le Arto Leminen Douglas A Levine Dong Liang Boon Kiong Lim Jie Lin Jolanta Lissowska Karen H Lu Jan Lubiński Galina Lurie Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Usha Menon Francesmary Modugno Kirsten B Moysich Toru Nakanishi Steven A Narod Lotte Nedergaard Roberta B Ness Heli Nevanlinna Stefan Nickels Houtan Noushmehr Kunle Odunsi Sara H Olson Irene Orlow James Paul Celeste L Pearce Tanja Pejovic Liisa M Pelttari Malcolm C Pike Elizabeth M Poole Paola Raska Stefan P Renner Harvey A Risch Lorna Rodriguez-Rodriguez Mary Anne Rossing Anja Rudolph Ingo B Runnebaum Iwona K Rzepecka Helga B Salvesen Ira Schwaab Gianluca Severi Viji Shridhar Xiao-Ou Shu Yurii B Shvetsov Weiva Sieh Honglin Song Melissa C Southey Beata Spiewankiewicz Daniel Stram Rebecca Sutphen Soo-Hwang Teo Kathryn L Terry Daniel C Tessier Pamela J Thompson Shelley S Tworoger Anne M van Altena Ignace Vergote Robert A Vierkant Daniel Vincent Allison F Vitonis Shan Wang-Gohrke Rachel Palmieri Weber Nicolas Wentzensen Alice S Whittemore Elisabeth Wik Lynne R Wilkens Boris Winterhoff Yin Ling Woo Anna H Wu Yong-Bing Xiang Hannah P Yang Wei Zheng Argyrios Ziogas Famida Zulkifli Catherine M Phelan Edwin Iversen Joellen M Schildkraut Andrew Berchuck Brooke L Fridley Ellen L Goode Paul D P Pharoah Alvaro N A Monteiro Thomas A Sellers Simon A Gayther

Nat Commun 2013 ;4:1627

Department of Cancer Epidemiology, Division of Population Sciences, Moffitt Cancer Center, Tampa, Florida, USA.

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http://dx.doi.org/10.1038/ncomms2613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709460PMC
October 2013

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.

Authors:
Hui Shen Brooke L Fridley Honglin Song Kate Lawrenson Julie M Cunningham Susan J Ramus Mine S Cicek Jonathan Tyrer Douglas Stram Melissa C Larson Martin Köbel Argyrios Ziogas Wei Zheng Hannah P Yang Anna H Wu Eva L Wozniak Yin Ling Woo Boris Winterhoff Elisabeth Wik Alice S Whittemore Nicolas Wentzensen Rachel Palmieri Weber Allison F Vitonis Daniel Vincent Robert A Vierkant Ignace Vergote David Van Den Berg Anne M Van Altena Shelley S Tworoger Pamela J Thompson Daniel C Tessier Kathryn L Terry Soo-Hwang Teo Claire Templeman Daniel O Stram Melissa C Southey Weiva Sieh Nadeem Siddiqui Yurii B Shvetsov Xiao-Ou Shu Viji Shridhar Shan Wang-Gohrke Gianluca Severi Ira Schwaab Helga B Salvesen Iwona K Rzepecka Ingo B Runnebaum Mary Anne Rossing Lorna Rodriguez-Rodriguez Harvey A Risch Stefan P Renner Elizabeth M Poole Malcolm C Pike Catherine M Phelan Liisa M Pelttari Tanja Pejovic James Paul Irene Orlow Siti Zawiah Omar Sara H Olson Kunle Odunsi Stefan Nickels Heli Nevanlinna Roberta B Ness Steven A Narod Toru Nakanishi Kirsten B Moysich Alvaro N A Monteiro Joanna Moes-Sosnowska Francesmary Modugno Usha Menon John R McLaughlin Valerie McGuire Keitaro Matsuo Noor Azmi Mat Adenan Leon F A G Massuger Galina Lurie Lene Lundvall Jan Lubiński Jolanta Lissowska Douglas A Levine Arto Leminen Alice W Lee Nhu D Le Sandrina Lambrechts Diether Lambrechts Jolanta Kupryjanczyk Camilla Krakstad Gottfried E Konecny Susanne Krüger Kjaer Lambertus A Kiemeney Linda E Kelemen Gary L Keeney Beth Y Karlan Rod Karevan Kimberly R Kalli Hiroaki Kajiyama Bu-Tian Ji Allan Jensen Anna Jakubowska Edwin Iversen Satoyo Hosono Claus K Høgdall Estrid Høgdall Maureen Hoatlin Peter Hillemanns Florian Heitz Rebecca Hein Philipp Harter Mari K Halle Per Hall Jacek Gronwald Martin Gore Marc T Goodman Graham G Giles Aleksandra Gentry-Maharaj Montserrat Garcia-Closas James M Flanagan Peter A Fasching Arif B Ekici Robert Edwards Diana Eccles Douglas F Easton Matthias Dürst Andreas du Bois Thilo Dörk Jennifer A Doherty Evelyn Despierre Agnieszka Dansonka-Mieszkowska Cezary Cybulski Daniel W Cramer Linda S Cook Xiaoqing Chen Bridget Charbonneau Jenny Chang-Claude Ian Campbell Ralf Butzow Clareann H Bunker Doerthe Brueggmann Robert Brown Angela Brooks-Wilson Louise A Brinton Natalia Bogdanova Matthew S Block Elizabeth Benjamin Jonathan Beesley Matthias W Beckmann Elisa V Bandera Laura Baglietto François Bacot Sebastian M Armasu Natalia Antonenkova Hoda Anton-Culver Katja K Aben Dong Liang Xifeng Wu Karen Lu Michelle A T Hildebrandt Joellen M Schildkraut Thomas A Sellers David Huntsman Andrew Berchuck Georgia Chenevix-Trench Simon A Gayther Paul D P Pharoah Peter W Laird Ellen L Goode Celeste Leigh Pearce

Nat Commun 2013 ;4:1628

USC Epigenome Center, Keck School of Medicine, University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.1038/ncomms2629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848248PMC
October 2013

Biallelic deleterious BRCA1 mutations in a woman with early-onset ovarian cancer.

Cancer Discov 2013 Apr 26;3(4):399-405. Epub 2012 Dec 26.

Abramson Cancer Center, Department of Medicine, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6160, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625496PMC
April 2013

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.

Authors:
Paul D P Pharoah Ya-Yu Tsai Susan J Ramus Catherine M Phelan Ellen L Goode Kate Lawrenson Melissa Buckley Brooke L Fridley Jonathan P Tyrer Howard Shen Rachel Weber Rod Karevan Melissa C Larson Honglin Song Daniel C Tessier François Bacot Daniel Vincent Julie M Cunningham Joe Dennis Ed Dicks Katja K Aben Hoda Anton-Culver Natalia Antonenkova Sebastian M Armasu Laura Baglietto Elisa V Bandera Matthias W Beckmann Michael J Birrer Greg Bloom Natalia Bogdanova James D Brenton Louise A Brinton Angela Brooks-Wilson Robert Brown Ralf Butzow Ian Campbell Michael E Carney Renato S Carvalho Jenny Chang-Claude Y Anne Chen Zhihua Chen Wong-Ho Chow Mine S Cicek Gerhard Coetzee Linda S Cook Daniel W Cramer Cezary Cybulski Agnieszka Dansonka-Mieszkowska Evelyn Despierre Jennifer A Doherty Thilo Dörk Andreas du Bois Matthias Dürst Diana Eccles Robert Edwards Arif B Ekici Peter A Fasching David Fenstermacher James Flanagan Yu-Tang Gao Montserrat Garcia-Closas Aleksandra Gentry-Maharaj Graham Giles Anxhela Gjyshi Martin Gore Jacek Gronwald Qi Guo Mari K Halle Philipp Harter Alexander Hein Florian Heitz Peter Hillemanns Maureen Hoatlin Estrid Høgdall Claus K Høgdall Satoyo Hosono Anna Jakubowska Allan Jensen Kimberly R Kalli Beth Y Karlan Linda E Kelemen Lambertus A Kiemeney Susanne Krüger Kjaer Gottfried E Konecny Camilla Krakstad Jolanta Kupryjanczyk Diether Lambrechts Sandrina Lambrechts Nhu D Le Nathan Lee Janet Lee Arto Leminen Boon Kiong Lim Jolanta Lissowska Jan Lubiński Lene Lundvall Galina Lurie Leon F A G Massuger Keitaro Matsuo Valerie McGuire John R McLaughlin Usha Menon Francesmary Modugno Kirsten B Moysich Toru Nakanishi Steven A Narod Roberta B Ness Heli Nevanlinna Stefan Nickels Houtan Noushmehr Kunle Odunsi Sara Olson Irene Orlow James Paul Tanja Pejovic Liisa M Pelttari Jenny Permuth-Wey Malcolm C Pike Elizabeth M Poole Xiaotao Qu Harvey A Risch Lorna Rodriguez-Rodriguez Mary Anne Rossing Anja Rudolph Ingo Runnebaum Iwona K Rzepecka Helga B Salvesen Ira Schwaab Gianluca Severi Hui Shen Vijayalakshmi Shridhar Xiao-Ou Shu Weiva Sieh Melissa C Southey Paul Spellman Kazuo Tajima Soo-Hwang Teo Kathryn L Terry Pamela J Thompson Agnieszka Timorek Shelley S Tworoger Anne M van Altena David van den Berg Ignace Vergote Robert A Vierkant Allison F Vitonis Shan Wang-Gohrke Nicolas Wentzensen Alice S Whittemore Elisabeth Wik Boris Winterhoff Yin Ling Woo Anna H Wu Hannah P Yang Wei Zheng Argyrios Ziogas Famida Zulkifli Marc T Goodman Per Hall Douglas F Easton Celeste L Pearce Andrew Berchuck Georgia Chenevix-Trench Edwin Iversen Alvaro N A Monteiro Simon A Gayther Joellen M Schildkraut Thomas A Sellers

Nat Genet 2013 Apr;45(4):362-70, 370e1-2

The Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.2564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693183PMC
April 2013

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.

Authors:
Stig E Bojesen Karen A Pooley Sharon E Johnatty Jonathan Beesley Kyriaki Michailidou Jonathan P Tyrer Stacey L Edwards Hilda A Pickett Howard C Shen Chanel E Smart Kristine M Hillman Phuong L Mai Kate Lawrenson Michael D Stutz Yi Lu Rod Karevan Nicholas Woods Rebecca L Johnston Juliet D French Xiaoqing Chen Maren Weischer Sune F Nielsen Melanie J Maranian Maya Ghoussaini Shahana Ahmed Caroline Baynes Manjeet K Bolla Qin Wang Joe Dennis Lesley McGuffog Daniel Barrowdale Andrew Lee Sue Healey Michael Lush Daniel C Tessier Daniel Vincent Françis Bacot Ignace Vergote Sandrina Lambrechts Evelyn Despierre Harvey A Risch Anna González-Neira Mary Anne Rossing Guillermo Pita Jennifer A Doherty Nuria Alvarez Melissa C Larson Brooke L Fridley Nils Schoof Jenny Chang-Claude Mine S Cicek Julian Peto Kimberly R Kalli Annegien Broeks Sebastian M Armasu Marjanka K Schmidt Linde M Braaf Boris Winterhoff Heli Nevanlinna Gottfried E Konecny Diether Lambrechts Lisa Rogmann Pascal Guénel Attila Teoman Roger L Milne Joaquin J Garcia Angela Cox Vijayalakshmi Shridhar Barbara Burwinkel Frederik Marme Rebecca Hein Elinor J Sawyer Christopher A Haiman Shan Wang-Gohrke Irene L Andrulis Kirsten B Moysich John L Hopper Kunle Odunsi Annika Lindblom Graham G Giles Hermann Brenner Jacques Simard Galina Lurie Peter A Fasching Michael E Carney Paolo Radice Lynne R Wilkens Anthony Swerdlow Marc T Goodman Hiltrud Brauch Montserrat Garcia-Closas Peter Hillemanns Robert Winqvist Matthias Dürst Peter Devilee Ingo Runnebaum Anna Jakubowska Jan Lubinski Arto Mannermaa Ralf Butzow Natalia V Bogdanova Thilo Dörk Liisa M Pelttari Wei Zheng Arto Leminen Hoda Anton-Culver Clareann H Bunker Vessela Kristensen Roberta B Ness Kenneth Muir Robert Edwards Alfons Meindl Florian Heitz Keitaro Matsuo Andreas du Bois Anna H Wu Philipp Harter Soo-Hwang Teo Ira Schwaab Xiao-Ou Shu William Blot Satoyo Hosono Daehee Kang Toru Nakanishi Mikael Hartman Yasushi Yatabe Ute Hamann Beth Y Karlan Suleeporn Sangrajrang Susanne Krüger Kjaer Valerie Gaborieau Allan Jensen Diana Eccles Estrid Høgdall Chen-Yang Shen Judith Brown Yin Ling Woo Mitul Shah Mat Adenan Noor Azmi Robert Luben Siti Zawiah Omar Kamila Czene Robert A Vierkant Børge G Nordestgaard Henrik Flyger Celine Vachon Janet E Olson Xianshu Wang Douglas A Levine Anja Rudolph Rachel Palmieri Weber Dieter Flesch-Janys Edwin Iversen Stefan Nickels Joellen M Schildkraut Isabel Dos Santos Silva Daniel W Cramer Lorna Gibson Kathryn L Terry Olivia Fletcher Allison F Vitonis C Ellen van der Schoot Elizabeth M Poole Frans B L Hogervorst Shelley S Tworoger Jianjun Liu Elisa V Bandera Jingmei Li Sara H Olson Keith Humphreys Irene Orlow Carl Blomqvist Lorna Rodriguez-Rodriguez Kristiina Aittomäki Helga B Salvesen Taru A Muranen Elisabeth Wik Barbara Brouwers Camilla Krakstad Els Wauters Mari K Halle Hans Wildiers Lambertus A Kiemeney Claire Mulot Katja K Aben Pierre Laurent-Puig Anne Mvan Altena Thérèse Truong Leon F A G Massuger Javier Benitez Tanja Pejovic Jose Ignacio Arias Perez Maureen Hoatlin M Pilar Zamora Linda S Cook Sabapathy P Balasubramanian Linda E Kelemen Andreas Schneeweiss Nhu D Le Christof Sohn Angela Brooks-Wilson Ian Tomlinson Michael J Kerin Nicola Miller Cezary Cybulski Brian E Henderson Janusz Menkiszak Fredrick Schumacher Nicolas Wentzensen Loic Le Marchand Hannah P Yang Anna Marie Mulligan Gord Glendon Svend Aage Engelholm Julia A Knight Claus K Høgdall Carmel Apicella Martin Gore Helen Tsimiklis Honglin Song Melissa C Southey Agnes Jager Ans M Wvan den Ouweland Robert Brown John W M Martens James M Flanagan Mieke Kriege James Paul Sara Margolin Nadeem Siddiqui Gianluca Severi Alice S Whittemore Laura Baglietto Valerie McGuire Christa Stegmaier Weiva Sieh Heiko Müller Volker Arndt France Labrèche Yu-Tang Gao Mark S Goldberg Gong Yang Martine Dumont John R McLaughlin Arndt Hartmann Arif B Ekici Matthias W Beckmann Catherine M Phelan Michael P Lux Jenny Permuth-Wey Bernard Peissel Thomas A Sellers Filomena Ficarazzi Monica Barile Argyrios Ziogas Alan Ashworth Aleksandra Gentry-Maharaj Michael Jones Susan J Ramus Nick Orr Usha Menon Celeste L Pearce Thomas Brüning Malcolm C Pike Yon-Dschun Ko Jolanta Lissowska Jonine Figueroa Jolanta Kupryjanczyk Stephen J Chanock Agnieszka Dansonka-Mieszkowska Arja Jukkola-Vuorinen Iwona K Rzepecka Katri Pylkäs Mariusz Bidzinski Saila Kauppila Antoinette Hollestelle Caroline Seynaeve Rob A E M Tollenaar Katarzyna Durda Katarzyna Jaworska Jaana M Hartikainen Veli-Matti Kosma Vesa Kataja Natalia N Antonenkova Jirong Long Martha Shrubsole Sandra Deming-Halverson Artitaya Lophatananon Pornthep Siriwanarangsan Sarah Stewart-Brown Nina Ditsch Peter Lichtner Rita K Schmutzler Hidemi Ito Hiroji Iwata Kazuo Tajima Chiu-Chen Tseng Daniel O Stram David van den Berg Cheng Har Yip M Kamran Ikram Yew-Ching Teh Hui Cai Wei Lu Lisa B Signorello Qiuyin Cai Dong-Young Noh Keun-Young Yoo Hui Miao Philip Tsau-Choong Iau Yik Ying Teo James McKay Charles Shapiro Foluso Ademuyiwa George Fountzilas Chia-Ni Hsiung Jyh-Cherng Yu Ming-Feng Hou Catherine S Healey Craig Luccarini Susan Peock Dominique Stoppa-Lyonnet Paolo Peterlongo Timothy R Rebbeck Marion Piedmonte Christian F Singer Eitan Friedman Mads Thomassen Kenneth Offit Thomas V O Hansen Susan L Neuhausen Csilla I Szabo Ignacio Blanco Judy Garber Steven A Narod Jeffrey N Weitzel Marco Montagna Edith Olah Andrew K Godwin Drakoulis Yannoukakos David E Goldgar Trinidad Caldes Evgeny N Imyanitov Laima Tihomirova Banu K Arun Ian Campbell Arjen R Mensenkamp Christi J van Asperen Kees E P van Roozendaal Hanne Meijers-Heijboer J Margriet Collée Jan C Oosterwijk Maartje J Hooning Matti A Rookus Rob B van der Luijt Theo A Mvan Os D Gareth Evans Debra Frost Elena Fineberg Julian Barwell Lisa Walker M John Kennedy Radka Platte Rosemarie Davidson Steve D Ellis Trevor Cole Brigitte Bressac-de Paillerets Bruno Buecher Francesca Damiola Laurence Faivre Marc Frenay Olga M Sinilnikova Olivier Caron Sophie Giraud Sylvie Mazoyer Valérie Bonadona Virginie Caux-Moncoutier Aleksandra Toloczko-Grabarek Jacek Gronwald Tomasz Byrski Amanda B Spurdle Bernardo Bonanni Daniela Zaffaroni Giuseppe Giannini Loris Bernard Riccardo Dolcetti Siranoush Manoukian Norbert Arnold Christoph Engel Helmut Deissler Kerstin Rhiem Dieter Niederacher Hansjoerg Plendl Christian Sutter Barbara Wappenschmidt Ake Borg Beatrice Melin Johanna Rantala Maria Soller Katherine L Nathanson Susan M Domchek Gustavo C Rodriguez Ritu Salani Daphne Gschwantler Kaulich Muy-Kheng Tea Shani Shimon Paluch Yael Laitman Anne-Bine Skytte Torben A Kruse Uffe Birk Jensen Mark Robson Anne-Marie Gerdes Bent Ejlertsen Lenka Foretova Sharon A Savage Jenny Lester Penny Soucy Karoline B Kuchenbaecker Curtis Olswold Julie M Cunningham Susan Slager Vernon S Pankratz Ed Dicks Sunil R Lakhani Fergus J Couch Per Hall Alvaro N A Monteiro Simon A Gayther Paul D P Pharoah Roger R Reddel Ellen L Goode Mark H Greene Douglas F Easton Andrew Berchuck Antonis C Antoniou Georgia Chenevix-Trench Alison M Dunning

Nat Genet 2013 Apr;45(4):371-84, 384e1-2

Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ng.2566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670748PMC
April 2013

Charting the landscape of tandem BRCT domain-mediated protein interactions.

Sci Signal 2012 Sep 18;5(242):rs6. Epub 2012 Sep 18.

Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1126/scisignal.2002255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064718PMC
September 2012

BRCT domains: A little more than kin, and less than kind.

FEBS Lett 2012 Aug 11;586(17):2711-6. Epub 2012 May 11.

Department of Biomolecular Engineering, University of California, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1016/j.febslet.2012.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413754PMC
August 2012

CHEKing out of mitosis.

Cell Cycle 2012 May 1;11(9):1756. Epub 2012 May 1.

H Lee Moffitt Cancer Center, Tampa, FL, USA.

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http://dx.doi.org/10.4161/cc.20315DOI Listing
May 2012

Yeast two-hybrid junk sequences contain selected linear motifs.

Nucleic Acids Res 2011 Oct 23;39(19):e128. Epub 2011 Jul 23.

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, 3400 N. Charles St, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1093/nar/gkr600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201885PMC
October 2011

Epigenetic tumor suppression by BRCA1.

Nat Med 2011 Oct 11;17(10):1183-5. Epub 2011 Oct 11.

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http://dx.doi.org/10.1038/nm.2493DOI Listing
October 2011

A computational method to classify variants of uncertain significance using functional assay data with application to BRCA1.

Cancer Epidemiol Biomarkers Prev 2011 Jun 29;20(6):1078-88. Epub 2011 Mar 29.

Department of Statistical Science, Duke University, Durham, North Carolina 27708, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-1
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http://dx.doi.org/10.1158/1055-9965.EPI-10-1214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111818PMC
June 2011

Tandem BRCT Domains: DNA's Praetorian Guard.

Genes Cancer 2010 Nov;1(11):1140-6

Instituto Federal de Educação Ciência e Tecnologia, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1177/1947601910392988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082952PMC
November 2010

Fine tuning chemotherapy to match BRCA1 status.

Biochem Pharmacol 2010 Sep 25;80(5):647-53. Epub 2010 May 25.

Risk Assessment, Detection, and Intervention Program, H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1016/j.bcp.2010.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925507PMC
September 2010

Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair.

Cell Cycle 2010 Apr 1;9(7):1421-33. Epub 2010 Apr 1.

Risk Assessment, Detection and Intervention Program, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040726PMC
http://dx.doi.org/10.4161/cc.9.7.11256DOI Listing
April 2010

BRCA1 protein and nucleolin colocalize in breast carcinoma tissue and cancer cell lines.

Am J Pathol 2010 Mar 14;176(3):1203-14. Epub 2010 Jan 14.

Department of Pathology, Box 1194, Mt. Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.2353/ajpath.2010.081063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832143PMC
March 2010

Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage.

Cell Cycle 2010 Feb 12;9(4):736-47. Epub 2010 Feb 12.

Risk Assessment, Detection and Intervention Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040716PMC
http://dx.doi.org/10.4161/cc.9.4.10613DOI Listing
February 2010

Ectopic expression of histone H2AX mutants reveals a role for its post-translational modifications.

Cancer Biol Ther 2009 Mar 9;8(5):422-34. Epub 2009 Mar 9.

Risk Assessment, Detection and Intervention Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612 , USA.

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http://dx.doi.org/10.4161/cbt.8.5.7592DOI Listing
March 2009

Assessment of functional effects of unclassified genetic variants.

Hum Mutat 2008 Nov;29(11):1314-26

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1002/humu.20899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771414PMC
November 2008

Somatic alterations in brain tumors.

Oncol Rep 2008 Jul;20(1):203-10

Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933973PMC
July 2008

Prevalence of BRCA1 and BRCA2 mutations in breast cancer patients from Brazil.

Breast Cancer Res Treat 2007 Jul 25;103(3):349-53. Epub 2006 Oct 25.

Department of Oncology, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1007/s10549-006-9378-6DOI Listing
July 2007

Functional assays for BRCA1 and BRCA2.

Int J Biochem Cell Biol 2007 18;39(2):298-310. Epub 2006 Aug 18.

Department of Risk Assessment, Detection, and Intervention, H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1016/j.biocel.2006.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1862449PMC
June 2007

The accidental cancer geneticist: hilário de gouvêa and hereditary retinoblastoma.

Cancer Biol Ther 2007 May 10;6(5):811-3. Epub 2007 May 10.

Risk Assessment, Detection, and Intervention Program, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida, USA.

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http://dx.doi.org/10.4161/cbt.6.5.4420DOI Listing
May 2007

Functional impact of missense variants in BRCA1 predicted by supervised learning.

PLoS Comput Biol 2007 Feb 28;3(2):e26. Epub 2006 Dec 28.

Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.0030026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797820PMC
February 2007

Functional implications of BRCA1 for early detection, prevention, and treatment of breast cancer.

Crit Rev Eukaryot Gene Expr 2006 ;16(3):233-52

Risk Assessment, Detection and Intervention Program, H Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

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December 2006

Long-term culture of cholangiocytes from liver fibro-granulomatous lesions.

BMC Gastroenterol 2006 Apr 3;6:13. Epub 2006 Apr 3.

Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21949, Brazil.

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http://dx.doi.org/10.1186/1471-230X-6-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448193PMC
April 2006

Cancer risk assessment at the atomic level.

Cancer Res 2006 Feb;66(4):1897-9

Risk Assessment, Detection, and Intervention Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-05-3034DOI Listing
February 2006

DNA damage response: determining the fate of phosphorylated histone H2AX.

Cancer Biol Ther 2006 Feb 20;5(2):142-4. Epub 2006 Feb 20.

Risk Assessment, Detection and Intervention Program, The H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida 33612, USA.

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http://dx.doi.org/10.4161/cbt.5.2.2530DOI Listing
February 2006

BRCA1 in breast and ovarian cancer predisposition.

Cancer Lett 2005 Sep 13;227(1):1-7. Epub 2004 Dec 13.

Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health Professions, St John's University, Jamaica, NY 11439, USA.

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http://dx.doi.org/10.1016/j.canlet.2004.11.006DOI Listing
September 2005

Breast cancer susceptibility and the DNA damage response.

Cancer Control 2005 Apr;12(2):127-36

Strang Cancer Prevention Center, New York, USA.

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http://dx.doi.org/10.1177/107327480501200210DOI Listing
April 2005

TGF beta1 and PDGF AA override collagen type I inhibition of proliferation in human liver connective tissue cells.

BMC Gastroenterol 2004 Dec 3;4:30. Epub 2004 Dec 3.

Departamento de Bioquímica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21949, Brazil.

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http://bmcgastroenterol.biomedcentral.com/articles/10.1186/1
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539266PMC
December 2004

Cancer variation associated with the position of the mutation in the BRCA2 gene.

Fam Cancer 2004 ;3(1):1-10

Hereditary Cancer Center-Department of Genetics and Pathology, Pomeranian Academy of Medicine, Szczecin, Poland.

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http://dx.doi.org/10.1023/B:FAME.0000026816.32400.45DOI Listing
July 2004

Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition.

Cancer Res 2004 Jun;64(11):3790-7

Laboratory of Molecular Biophysics, Pels Family Center for Biochemistry and Structural Biology, Rockefeller University, New York, New York, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-03-3009DOI Listing
June 2004

Understanding germ-line mutations in BRCA1.

Cancer Biol Ther 2004 Jun 1;3(6):515-20. Epub 2004 Jun 1.

Unit of Genetic Epidemiology, International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.4161/cbt.3.6.841DOI Listing
June 2004

Methods to classify BRCA1 variants of uncertain clinical significance: the more the merrier.

Cancer Biol Ther 2004 May 7;3(5):458-9. Epub 2004 May 7.

Department of Pharmaceutical Sciences, College of Pharmacy and Allied Health, St. John's University, Jamaica, New York, USA.

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http://dx.doi.org/10.4161/cbt.3.5.831DOI Listing
May 2004

A naturally occurring allele of BRCA1 coding for a temperature-sensitive mutant protein.

Cancer Biol Ther 2002 Sep-Oct;1(5):497-501

Strang Cancer Prevention Center, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.4161/cbt.1.5.164DOI Listing
August 2003

Mutations in the BRCT domain confer temperature sensitivity to BRCA1 in transcription activation.

Cancer Biol Ther 2002 Sep-Oct;1(5):502-8

Strang Cancer Prevention Center, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.4161/cbt.1.5.165DOI Listing
August 2003

BRCA1: the enigma of tissue-specific tumor development.

Trends Genet 2003 Jun;19(6):312-5

Department of Cell and Developmental Biology, Weill Medical College of Cornell University, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/S0168-9525(03)00110-0DOI Listing
June 2003

Participation of BRCA1 in the DNA repair response...via transcription.

Cancer Biol Ther 2002 Mar-Apr;1(2):187-8

Laboratory of Molecular Oncology, Strong Cancer Prevention Center and Department of Cell Biology, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.4161/cbt.66DOI Listing
September 2002