Allan Walker

Allan Walker

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The developmentally regulated fetal enterocyte gene, , mediates anti-inflammation by the symbiotic bacterial surface factor polysaccharide A on .

Am J Physiol Gastrointest Liver Physiol 2019 Oct 17;317(4):G398-G407. Epub 2019 Jul 17.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Boston, Massachusetts.

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http://dx.doi.org/10.1152/ajpgi.00046.2019DOI Listing
October 2019

A practical guide to pre-trial simulations for Bayesian adaptive trials using SAS and BUGS.

Pharm Stat 2018 11 14;17(6):854-865. Epub 2018 Sep 14.

Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.

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http://doi.wiley.com/10.1002/pst.1897
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http://dx.doi.org/10.1002/pst.1897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283249PMC
November 2018

Summary of Evolution of Human Microbiota.

Authors:
W Allan Walker

Nestle Nutr Inst Workshop Ser 2017 27;88:55-56. Epub 2017 Mar 27.

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http://dx.doi.org/10.1159/000455214DOI Listing
April 2018

Helminth infection protects against high fat diet-induced obesity via induction of alternatively activated macrophages.

Sci Rep 2018 03 15;8(1):4607. Epub 2018 Mar 15.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, USA.

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http://dx.doi.org/10.1038/s41598-018-22920-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854586PMC
March 2018

Bacterial Colonization of the Newborn Gut, Immune Development, and Prevention of Disease.

Authors:
W Allan Walker

Nestle Nutr Inst Workshop Ser 2017 27;88:23-33. Epub 2017 Mar 27.

Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Charlestown, MA, and Division of Nutrition, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1159/000455210DOI Listing
November 2017

The importance of appropriate initial bacterial colonization of the intestine in newborn, child, and adult health.

Authors:
W Allan Walker

Pediatr Res 2017 Sep 17;82(3):387-395. Epub 2017 May 17.

Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology, Massachusetts General Hospital for Children, Division of Nutrition, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1038/pr.2017.111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570628PMC
September 2017

The symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis inhibits IL-1β-induced inflammation in human fetal enterocytes via toll receptors 2 and 4.

PLoS One 2017 9;12(3):e0172738. Epub 2017 Mar 9.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172738PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344356PMC
August 2017

Long-Term Randomized Trial of Intensive Versus Symptomatic Management in Paget's Disease of Bone: The PRISM-EZ Study.

J Bone Miner Res 2017 Jun 8;32(6):1165-1173. Epub 2017 Feb 8.

Centre for Genomic and Experimental Medicine, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK.

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http://dx.doi.org/10.1002/jbmr.3066DOI Listing
June 2017

Human fetal intestinal epithelial cells metabolize and incorporate branched chain fatty acids in a structure specific manner.

Prostaglandins Leukot Essent Fatty Acids 2017 01 10;116:32-39. Epub 2016 Dec 10.

Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.plefa.2016.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260611PMC
January 2017

Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants.

Microbiome 2016 12 30;4(1):68. Epub 2016 Dec 30.

Department of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/s40168-016-0214-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5200970PMC
December 2016

Anti-inflammatory effects of Bifidobacterium longum subsp infantis secretions on fetal human enterocytes are mediated by TLR-4 receptors.

Am J Physiol Gastrointest Liver Physiol 2016 10 25;311(4):G744-G753. Epub 2016 Aug 25.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, Boston, Massachusetts

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http://dx.doi.org/10.1152/ajpgi.00090.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142200PMC
October 2016

Recommendations for Probiotic Use--2015 Update: Proceedings and Consensus Opinion.

J Clin Gastroenterol 2015 Nov-Dec;49 Suppl 1:S69-73

*Department of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT †Harvard Medical School ‡Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Boston ††Department of Transplantation, Lahey Hospital and Medical Center, Burlington, MA §Dairy & Food Culture Technologies, International Scientific Association of Probiotics and Prebiotics (ISAPP), Sacramento **Department of Medicine, University of California, San Diego, San Diego, CA ∥Departments of Internal Medicine, Academic Medical Center and VUmC, Amsterdam, The Netherlands ¶Wallenberg Laboratory, Gothenborg University, Gothenburg, Sweden #Minnesota Gastroenterology P.A., Minnesota, MN ‡‡Pediatric Liver & Liver Transplant, Gastroenterology/Transplantation, Phoenix Children's Hospital ∥∥Mayo Clinic, Phoenix §§Department of Pediatrics, University of Arizona, Tucson, AZ ¶¶Department of Translational Medical Sciences, Section of Pediatrics, University of Naples Federico II, Naples ##Clinical Hepato-Gastroenterology Unit, Division of Gastroenterology & Digestive Endoscopy, S. Raffaele University Hospital, Milano, Italy ***Division of Gastroenterology, University of Alberta, Edmonton, AB, Canada †††Department of Gastroenterology, University of North Carolina School of Medicine, Chapel Hill, NC ‡‡‡The Lynda K. and David M. Underwood Center for Digestive Disorders, Houston Methodist Hospital, Houston, TX §§§Department of Medicine, Weill Cornell Medical College, New York ∥∥∥Department of Medicine and Surgery, Division of Gastroenterology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.

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http://dx.doi.org/10.1097/MCG.0000000000000420DOI Listing
July 2016

From Birth to "Immunohealth," Allergies and Enterocolitis.

J Clin Gastroenterol 2015 Nov-Dec;49 Suppl 1:S7-S12

*Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Charlestown †University of Massachusetts Medical School, Worcester, MA.

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http://dx.doi.org/10.1097/MCG.0000000000000355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602161PMC
July 2016

Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte.

PLoS One 2016 22;11(1):e0145184. Epub 2016 Jan 22.

Mucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital for Children, and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145184PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723075PMC
July 2016

Hydrocortisone-induced anti-inflammatory effects in immature human enterocytes depend on the timing of exposure.

Am J Physiol Gastrointest Liver Physiol 2016 06 7;310(11):G920-9. Epub 2016 Apr 7.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Boston, Massachusetts; and Section of Neonatology, Department of Pediatrics, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1152/ajpgi.00457.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935478PMC
June 2016

Presence of commensal house dust mite allergen in human gastrointestinal tract: a potential contributor to intestinal barrier dysfunction.

Gut 2016 May 8;65(5):757-66. Epub 2015 Dec 8.

Université de Nice Sophia-Antipolis, EA 6302 Immune Tolerance (TIM), Nice, France The International Inflammation 'in-FLAME' Network, Worldwide Universities Network.

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http://dx.doi.org/10.1136/gutjnl-2015-310523DOI Listing
May 2016

Secreted Metabolites of Bifidobacterium infantis and Lactobacillus acidophilus Protect Immature Human Enterocytes from IL-1β-Induced Inflammation: A Transcription Profiling Analysis.

PLoS One 2015 23;10(4):e0124549. Epub 2015 Apr 23.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children and Harvard Medical School, Charlestown, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124549PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407962PMC
April 2016

Longitudinal analysis of the premature infant intestinal microbiome prior to necrotizing enterocolitis: a case-control study.

PLoS One 2015 5;10(3):e0118632. Epub 2015 Mar 5.

Department of Newborn Medicine, Brigham and Women's Hospital, Boston, MA, United States of America; Department of Nursing, Brigham and Women's Hospital, Boston, MA, United States of America; Harvard Medical School, Boston, MA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118632PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351051PMC
February 2016

Long-chain polyunsaturated fatty acids attenuate the IL-1β-induced proinflammatory response in human fetal intestinal epithelial cells.

Pediatr Res 2015 Dec 13;78(6):626-33. Epub 2015 Aug 13.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Boston, Massachusetts.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046822PMC
http://dx.doi.org/10.1038/pr.2015.154DOI Listing
December 2015

The very low birth weight infant microbiome and childhood health.

Birth Defects Res C Embryo Today 2015 Dec 10;105(4):252-64. Epub 2015 Dec 10.

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/bdrc.21115DOI Listing
December 2015

Intestinal colonization and programming of the intestinal immune response.

Authors:
Allan Walker

J Clin Gastroenterol 2014 Nov-Dec;48 Suppl 1:S8-11

Department of Pediatrics, Division of Pediatric, Gastroenterology, Hepatology and Nutrition, Harvard Medical School, Mucosal Immunology and Biology Research Center, MassGeneral Hospital for Children, Boston, MA.

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http://dx.doi.org/10.1097/MCG.0000000000000230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189825PMC
June 2015

Why is initial bacterial colonization of the intestine important to infants' and children's health?

J Pediatr Gastroenterol Nutr 2015 Mar;60(3):294-307

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Charlestown.

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http://dx.doi.org/10.1097/MPG.0000000000000597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340742PMC
March 2015

Toll-like receptor-4 in human and mouse colonic epithelium is developmentally regulated: a possible role in necrotizing enterocolitis.

Pediatr Res 2015 Mar 18;77(3):416-24. Epub 2014 Dec 18.

Department of Pediatrics, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Boston, Massachusetts.

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http://dx.doi.org/10.1038/pr.2014.207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479150PMC
March 2015

Diet and host-microbial crosstalk in postnatal intestinal immune homeostasis.

Nat Rev Gastroenterol Hepatol 2015 Jan 9;12(1):14-25. Epub 2014 Sep 9.

Mucosal Immunology and Biology Research Centre, Massachusetts General Hospital, Building 114, 16th Street, Charlestown, MA 02129-4404, USA.

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http://dx.doi.org/10.1038/nrgastro.2014.153DOI Listing
January 2015

Breast milk, microbiota, and intestinal immune homeostasis.

Pediatr Res 2015 Jan 13;77(1-2):220-8. Epub 2014 Oct 13.

Department of Pediatrics, MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1038/pr.2014.160DOI Listing
January 2015

Activation of epidermal growth factor receptor mediates mucin production stimulated by p40, a Lactobacillus rhamnosus GG-derived protein.

J Biol Chem 2014 Jul 3;289(29):20234-44. Epub 2014 Jun 3.

From the Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee 37232,

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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.553800
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http://dx.doi.org/10.1074/jbc.M114.553800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106339PMC
July 2014

Initial intestinal colonization in the human infant and immune homeostasis.

Authors:
W Allan Walker

Ann Nutr Metab 2013 8;63 Suppl 2:8-15. Epub 2013 Nov 8.

Harvard Medical School, Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Boston, Mass., USA.

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http://dx.doi.org/10.1159/000354907DOI Listing
June 2014

Conditioned medium from Bifidobacteria infantis protects against Cronobacter sakazakii-induced intestinal inflammation in newborn mice.

Am J Physiol Gastrointest Liver Physiol 2014 May 13;306(9):G779-87. Epub 2014 Mar 13.

Mucosal Immunology and Biology Research Center, Division of Pediatric Gastroenterology, Harvard Medical School, Boston, Massachusetts; and Mass General Hospital for Children, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1152/ajpgi.00183.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010653PMC
May 2014

Immunologic Factors in Human Milk and Disease Prevention in the Preterm Infant.

Curr Pediatr Rep 2013 Dec;1(4)

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children, Harvard Medical School, 114 16th Street, Charlestown, MA, USA,

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http://dx.doi.org/10.1007/s40124-013-0028-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877694PMC
December 2013

New insights into probiotic mechanisms: a harvest from functional and metagenomic studies.

Gut Microbes 2013 Mar-Apr;4(2):94-100. Epub 2012 Dec 18.

Pathology and Molecular Medicine, McMaster University, Hamilton, ON Canada.

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http://dx.doi.org/10.4161/gmic.23283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595083PMC
August 2013

Authors' response.

J Pediatr Gastroenterol Nutr 2013 Jul;57(1):e9-10

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http://dx.doi.org/10.1097/mpg.0b013e3182923787DOI Listing
July 2013

Probiotics and the mechanism of necrotizing enterocolitis.

Semin Pediatr Surg 2013 May;22(2):94-100

Division of Gastroenterology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan, Republic of China.

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http://dx.doi.org/10.1053/j.sempedsurg.2013.01.006DOI Listing
May 2013

Probiotics prevent necrotizing enterocolitis by modulating enterocyte genes that regulate innate immune-mediated inflammation.

Am J Physiol Gastrointest Liver Physiol 2013 Jan 8;304(2):G132-41. Epub 2012 Nov 8.

Mucosal Immunology Laboratory, Division of Pediatric Gastroenterology, Massachusetts General Hospital for Children, 114 16th St. (114-3503), Charlestown, MA 02192-4404, USA.

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http://www.physiology.org/doi/10.1152/ajpgi.00142.2012
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http://dx.doi.org/10.1152/ajpgi.00142.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543644PMC
January 2013

Method development for fecal lipidomics profiling.

Anal Chem 2013 Jan 26;85(2):1114-23. Epub 2012 Dec 26.

Boston College, W.F. Connell School of Nursing, 140 Commonwealth Avenue, Chestnut Hill, Massachusetts 02467, USA.

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http://dx.doi.org/10.1021/ac303011kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928122PMC
January 2013

Treatment of necrotizing enterocolitis with probiotics.

Gastroenterol Clin North Am 2012 Dec 5;41(4):733-46. Epub 2012 Oct 5.

Mucosal Immunology Laboratory, Division of Pediatric Gastroenterology, Massachusetts General Hospital for Children, Harvard Medical School, Charlestown, MA 02129-4404, USA.

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http://dx.doi.org/10.1016/j.gtc.2012.08.004DOI Listing
December 2012

Current opinion in gastroenterology.

Authors:
W Allan Walker

Curr Opin Gastroenterol 2012 Nov;28(6):547-50

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http://dx.doi.org/10.1097/MOG.0b013e32835955efDOI Listing
November 2012

The messages they send: e-mail use by adolescents with and without a history of specific language impairment (SLI).

Int J Lang Commun Disord 2012 Mar-Apr;47(2):217-28. Epub 2011 Oct 25.

Human Communication and Deafness, School of Psychological Sciences, University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1111/j.1460-6984.2011.00096.x
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http://dx.doi.org/10.1111/j.1460-6984.2011.00096.xDOI Listing
August 2012

Early administration of probiotic Lactobacillus acidophilus and/or prebiotic inulin attenuates pathogen-mediated intestinal inflammation and Smad 7 cell signaling.

FEMS Immunol Med Microbiol 2012 Aug 25;65(3):467-80. Epub 2012 May 25.

Mucosal Immunology Laboratory, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.

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http://dx.doi.org/10.1111/j.1574-695X.2012.00978.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015462PMC
August 2012

The role of phosphoinositide 3-kinase signaling in intestinal inflammation.

J Signal Transduct 2012 9;2012:358476. Epub 2012 Apr 9.

Mucosal Immunology Laboratory, Department of Pediatrics, 114 16th Street, Massachusetts General Hospital for Children, Charlestown MA 02129, USA.

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http://dx.doi.org/10.1155/2012/358476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337621PMC
August 2012

Helminth infection impairs autophagy-mediated killing of bacterial enteropathogens by macrophages.

J Immunol 2012 Aug 25;189(3):1459-66. Epub 2012 Jun 25.

Mucosal Immunology Laboratory, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.4049/jimmunol.1200484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423331PMC
August 2012

Oral inoculation of probiotics Lactobacillus acidophilus NCFM suppresses tumour growth both in segmental orthotopic colon cancer and extra-intestinal tissue.

Br J Nutr 2012 Jun 30;107(11):1623-34. Epub 2011 Sep 30.

Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Chang Gung Children's Hospital, 12L, 5 Fu-Hsing Street, Kwei-Shan, Taoyuan 333, Taiwan, ROC.

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http://dx.doi.org/10.1017/S0007114511004934DOI Listing
June 2012

Early gut colonization and subsequent obesity risk.

Curr Opin Clin Nutr Metab Care 2012 May;15(3):278-84

Department of Pediatrics and Mucosal Immunology Laboratory, MassGeneral Hospital for Children and Harvard Medical School, Boston, MA 02129-4404, USA.

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http://dx.doi.org/10.1097/MCO.0b013e32835133cbDOI Listing
May 2012

Probiotics are considered nutritional supplements.

J Clin Gastroenterol 2011 Nov;45 Suppl:S107

Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06510, USA.

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https://insights.ovid.com/crossref?an=00004836-201111001-000
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http://dx.doi.org/10.1097/MCG.0b013e3182317e74DOI Listing
November 2011

Probiotics in the prevention of necrotizing enterocolitis.

J Clin Gastroenterol 2011 Nov;45 Suppl:S133-8

Department of Pediatric Gastroenterology, Harvard Medical School, Mucosal Immunology Laboratory, Massachusetts General Hospital for Children, Boston, MA 02129-4404, USA.

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http://dx.doi.org/10.1097/MCG.0b013e318228b799DOI Listing
November 2011

Recommendations for probiotic use-2011 update.

J Clin Gastroenterol 2011 Nov;45 Suppl:S168-71

Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06150, USA.

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http://dx.doi.org/10.1097/MCG.0b013e318230928bDOI Listing
November 2011

Immunology.

Authors:
W Allan Walker

Curr Opin Gastroenterol 2011 Oct;27(6):493-5

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http://dx.doi.org/10.1097/MOG.0b013e32834bf223DOI Listing
October 2011

Clinical applications of probiotics in gastrointestinal disorders in children.

Natl Med J India 2011 May-Jun;24(3):153-60

Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.

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September 2011

Breast milk-transforming growth factor-β₂ specifically attenuates IL-1β-induced inflammatory responses in the immature human intestine via an SMAD6- and ERK-dependent mechanism.

Neonatology 2011 25;99(3):192-201. Epub 2010 Sep 25.

Developmental Gastroenterology Laboratory, Division of Pediatric Gastroenterology, Massachusetts General Hospital for Children, Charlestown, Mass., USA.

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https://www.karger.com/Article/FullText/314109
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http://dx.doi.org/10.1159/000314109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214931PMC
August 2011

The role of microbes in developmental immunologic programming.

Pediatr Res 2011 Jun;69(6):465-72

Department of Pediatrics and Mucosal Immunology Laboratory, MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1203/PDR.0b013e318217638aDOI Listing
June 2011

Duodenal helminth infection alters barrier function of the colonic epithelium via adaptive immune activation.

Infect Immun 2011 Jun 28;79(6):2285-94. Epub 2011 Mar 28.

Mucosal Immunology Laboratory, Massachusetts General Hospital, Building 114, 16th Street, Room 3504, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1128/IAI.01123-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3125859PMC
June 2011

Hydrocortisone induces changes in gene expression and differentiation in immature human enterocytes.

Am J Physiol Gastrointest Liver Physiol 2011 Mar 9;300(3):G425-32. Epub 2010 Dec 9.

Developmental Gastroenterology Laboratory, Massachusetts General Hospital for Children, Boston, USA.

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http://dx.doi.org/10.1152/ajpgi.00011.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064117PMC
March 2011

Necrotizing enterocolitis.

N Engl J Med 2011 Jan;364(3):255-64

Department of Pediatrics, University of Florida, Gainesville, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMra1005408
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http://dx.doi.org/10.1056/NEJMra1005408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3628622PMC
January 2011

Editorial overview: immunology section.

Authors:
W Allan Walker

Curr Opin Gastroenterol 2010 Nov;26(6):543-6

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http://dx.doi.org/10.1097/MOG.0b013e32833fa744DOI Listing
November 2010

Probiotics and the gut microbiota in intestinal health and disease.

Nat Rev Gastroenterol Hepatol 2010 Sep 27;7(9):503-14. Epub 2010 Jul 27.

Cell Biology Program, Research Institute, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

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http://dx.doi.org/10.1038/nrgastro.2010.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748966PMC
September 2010

State of research in pediatric gastroenterology, hepatology, and nutrition: 2010 and beyond.

Gastroenterology 2010 Feb 16;138(2):411-6, 416.e1-2. Epub 2009 Dec 16.

Harvard Medical School, Mucosal Immunology Laboratory, Massachusetts General Hospital for Children, Boston, Massachusetts 02129-4404, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001650850902195
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http://dx.doi.org/10.1053/j.gastro.2009.12.034DOI Listing
February 2010

Mead Johnson Symposium: functional proteins in human milk: role in infant health and development.

Authors:
W Allan Walker

J Pediatr 2010 Feb;156(2 Suppl):S1-2

Department of Nutrition, Harvard Medical School, Harvard School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jpeds.2009.11.013DOI Listing
February 2010

Breast milk as the gold standard for protective nutrients.

Authors:
Allan Walker

J Pediatr 2010 Feb;156(2 Suppl):S3-7

Department of Nutrition, Harvard Medical School and Harvard School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jpeds.2009.11.021DOI Listing
February 2010

Immunology.

Authors:
W Allan Walker

Curr Opin Gastroenterol 2009 Nov;25(6):491-5

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http://dx.doi.org/10.1097/MOG.0b013e3283325d19DOI Listing
November 2009

ADP-ribosylation factors regulate the development of CT signaling in immature human enterocytes.

Am J Physiol Gastrointest Liver Physiol 2009 Jun 9;296(6):G1221-9. Epub 2009 Apr 9.

Developmental Gastroenterology Lab., Massachusetts General Hospital for Children, Charlestown, MA 02129-4404, USA.

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http://dx.doi.org/10.1152/ajpgi.90686.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697949PMC
June 2009

The long-term health effects of neonatal microbial flora.

Curr Opin Allergy Clin Immunol 2009 Jun;9(3):197-201

Division of Allergy and Immunology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1097/ACI.0b013e32832b3f1dDOI Listing
June 2009

Academy of Breastfeeding Medicine founder's lecture 2008: breastfeeding--an extrauterine link between mother and child.

Breastfeed Med 2009 Mar;4(1):3-10

Developmental Gastroenterology Laboratory, Division of Pediatric Gastroenterology, Massachusetts General Hospital for Children, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1089/bfm.2009.0004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932545PMC
March 2009

Educational and interpersonal uses of home computers by adolescents with and without specific language impairment.

Br J Dev Psychol 2009 Mar;27(Pt 1):197-217

Department of Psychology, University of Strathclyde, Glasgow, UK.

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March 2009

Effect of probiotics Lactobacillus acidophilus on Citrobacter rodentium colitis: the role of dendritic cells.

Pediatr Res 2009 Feb;65(2):169-75

Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taoyuan, 333, Taiwan.

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http://dx.doi.org/10.1203/PDR.0b013e31818d5a06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206789PMC
February 2009

Intestinal immune health.

Nestle Nutr Workshop Ser Pediatr Program 2008 ;62:111-21; discussion 121-5

Mucosal Immunology and Developmental Gastroenterology Laboratories, Massachusetts General Hospital for Children, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1159/000146255DOI Listing
November 2008

Immunology section.

Authors:
W Allan Walker

Curr Opin Gastroenterol 2008 Nov;24(6):698-700

Mucosal Immunology Laboratory, Harvard Clinical Nutrition Research Center, Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital for Children, Boston, MA 02129-4404, USA.

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http://dx.doi.org/10.1097/MOG.0b013e3283126971DOI Listing
November 2008

Relapse after emergency department discharge for acute asthma.

Acad Emerg Med 2008 Aug 11;15(8):709-17. Epub 2008 Jul 11.

Department of Emergency Medicine, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1553-2712.2008.00176.xDOI Listing
August 2008

Hydrocortisone modulates cholera toxin endocytosis by regulating immature enterocyte plasma membrane phospholipids.

Gastroenterology 2008 Jul 22;135(1):185-193.e1. Epub 2008 Mar 22.

Developmental Gastroenterology Laboratory, Massachusetts General Hospital for Children, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1053/j.gastro.2008.03.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587123PMC
July 2008

Advances in clinical use of probiotics.

J Clin Gastroenterol 2008 Jul;42 Suppl 2:S45

Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1097/MCG.0b013e31816b9053DOI Listing
July 2008

Bacterial colonization, probiotics, and necrotizing enterocolitis.

J Clin Gastroenterol 2008 Jul;42 Suppl 2:S46-52

Department of Pediatrics, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1097/MCG.0b013e31815a57a8DOI Listing
July 2008

Recommendations for probiotic use--2008.

J Clin Gastroenterol 2008 Jul;42 Suppl 2:S104-8

Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT 06520-8019, USA.

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http://dx.doi.org/10.1097/MCG.0b013e31816b903fDOI Listing
July 2008

Neonatal microbial flora and disease outcome.

Nestle Nutr Workshop Ser Pediatr Program 2008 ;61:211-24

Mucosal Immunology and Developmental Gastroenterology Laboratories, Massachusetts General Hospital for Children, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1159/000113496DOI Listing
April 2008

Probiotics: role in pathophysiology and prevention in necrotizing enterocolitis.

Semin Perinatol 2008 Apr;32(2):127-37

Department of Pediatrics, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1053/j.semperi.2008.01.006DOI Listing
April 2008

Mechanisms of action of probiotics.

Authors:
W Allan Walker

Clin Infect Dis 2008 Feb;46 Suppl 2:S87-91; discussion S144-51

Division of Nutrition and Department of Pediatrics, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1086/523335DOI Listing
February 2008

Say hello to the bugs in your gut.

Newsweek 2007 Dec;150(24):75-6

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December 2007

Butyrate regulates the expression of pathogen-triggered IL-8 in intestinal epithelia.

Pediatr Res 2007 Nov;62(5):542-6

Department of Pediatrics, Division of Pediatric Gastroenterology and Nutrition, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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http://dx.doi.org/10.1203/PDR.0b013e318155a422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201723PMC
November 2007

Immunology.

Authors:
W Allan Walker

Curr Opin Gastroenterol 2007 Nov;23(6):644-6

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http://dx.doi.org/10.1097/MOG.0b013e3282f0769bDOI Listing
November 2007

The role of TIM-4 in food allergy.

Gastroenterology 2007 Nov;133(5):1723-6

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http://dx.doi.org/10.1053/j.gastro.2007.09.047DOI Listing
November 2007

New therapies and preventive approaches for necrotizing enterocolitis: report of a research planning workshop.

Pediatr Res 2007 Oct;62(4):510-4

Endocrinology, Nutrition and Growth Branch, National Institute of Child Health and Development/National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1203/PDR.0b013e318142580aDOI Listing
October 2007

Bacterial symbionts induce a FUT2-dependent fucosylated niche on colonic epithelium via ERK and JNK signaling.

Am J Physiol Gastrointest Liver Physiol 2007 Oct 2;293(4):G780-7. Epub 2007 Aug 2.

Developmental Gastroenterology Laboratory, Massachusetts General Hospital-East, 114 16th St., Rm 3650, Charlestown, MA 02129, USA.

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http://www.physiology.org/doi/10.1152/ajpgi.00010.2007
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http://dx.doi.org/10.1152/ajpgi.00010.2007DOI Listing
October 2007

Commensal bacteria and epithelial cross talk in the developing intestine.

Curr Gastroenterol Rep 2007 Oct;9(5):385-92

Mucosal Immunology Laboratory, Massachusetts General Hospital, 114 16th Street (114-3503), Charlestown, MA 02129-4404, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208513PMC
October 2007

Starting the good life in the womb.

Newsweek 2007 Sep;150(12):56, 58

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September 2007

Symposium introduction: metabolic syndrome and the onset of cancer.

Am J Clin Nutr 2007 09;86(3):s817-9

Division of Nutrition, Harvard Medical School, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144325PMC
http://dx.doi.org/10.1093/ajcn/86.3.817SDOI Listing
September 2007

Secreted probiotic factors ameliorate enteropathogenic infection in zinc-deficient human Caco-2 and T84 cell lines.

Pediatr Res 2007 Aug;62(2):139-44

Department of Pediatrics, Mucosal Immunology and Developmental Gastroenterology Laboratories, Massachusetts General Hospital for Children, Harvard Medical School, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1203/PDR.0b013e31809fd85eDOI Listing
August 2007

Protection of the neonate by the innate immune system of developing gut and of human milk.

Pediatr Res 2007 Jan;61(1):2-8

Pediatric Gastroenterology and Nutrition Unit, MassGeneral Hospital for Children and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1203/01.pdr.0000250274.68571.18DOI Listing
January 2007

State of pediatric gastroenterology, hepatology, and nutrition: 2006 and beyond.

Gastroenterology 2007 Jan;132(1):434-6

Harvard Medical School and Mucosal Immunology Laboratory, Massachusetts General Hospital for Children, 114 16th Street, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1053/j.gastro.2006.10.066DOI Listing
January 2007

Immunology.

Authors:
W Allan Walker

Curr Opin Gastroenterol 2006 Nov;22(6):641-3

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http://dx.doi.org/10.1097/01.mog.0000245531.35518.77DOI Listing
November 2006

T helper cell subclasses and clinical disease states.

Curr Opin Gastroenterol 2002 Nov;18(6):711-6

Mucosal Immunology Laboratory, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA.

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November 2002