Allan Struthers

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Allan Struthers

Publications by authors named "Allan Struthers"

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100Publications

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Prevalence and Distribution of Atherosclerosis in a Low- to Intermediate-Risk Population: Assessment with Whole-Body MR Angiography.

Radiology 2018 Jun 1;287(3):795-804. Epub 2018 May 1.

From the Division of Molecular and Clinical Medicine, College of Medicine, University of Dundee, Level 7, Ninewells Hospital, Dundee DD1 9SY, Scotland (M.A.L., J.R.W.M., M.S., D.L., R.L., S.Z.M., A.D.S., J.J.F.B., J.G.H.); NHS Tayside Medical Physics, Ninewells Hospital, Dundee, Scotland (S.J.G., I.C., J.A.M., R.S.N., S.A.H.); Department of Research and Innovation, North York General Hospital, University of Toronto, Toronto, Canada (F.S.); and Department of Clinical Radiology, University Hospital of Wales, Cardiff, Wales (R.D.W.).

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June 2018

Acceptability and feasibility of magnetic femoral nerve stimulation in older, functionally impaired patients.

BMC Res Notes 2018 Jun 15;11(1):394. Epub 2018 Jun 15.

Division of Molecular and Clinical Medicine, Ninewells Hospital, University of Dundee, Dundee, Scotland, UK.

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June 2018

Development and Validation of a Path Length Calculation for Carotid-Femoral Pulse Wave Velocity Measurement: A TASCFORCE, SUMMIT, and Caerphilly Collaborative Venture.

Hypertension 2018 May 19;71(5):937-945. Epub 2018 Mar 19.

From the Division of Molecular and Clinical Medicine, College of Medicine, University of Dundee, United Kingdom (J.R.W.-M., L.B., J.S., F.K., A.D.S., J.G.H.); NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, United Kingdom (P.T., M.B.-M., S.C.C.); Department of Research and Innovation, North York General Hospital, University of Toronto, Canada (F.S.); Centre for Genomic and Experimental Medicine, The University of Edinburgh, Western General Hospital, United Kingdom (H.M.C.); NIHR Exeter Clinical Research Facility, Royal Devon and Exeter Hospital and University of Exeter Medical School, United Kingdom (A.C.S., K.A.); Lund University Diabetes Centre, Lund University, Malmö, Sweden (L.G.); Department of Clinical Sciences Malmö, Lund University, Sweden (J.N.); Department of Cardiology, Wales Heart Research Institute, Cardiff, United Kingdom (J.R.C.); Division of Experimental Medicine & Immunotherapeutics, University of Cambridge, United Kingdom (C.M.M., I.B.W.); and Population Health Sciences, University of Bristol, United Kingdom (Y.B.-S.).

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May 2018

Disconnection of pulmonary and systemic arterial stiffness in COPD.

Int J Chron Obstruct Pulmon Dis 2018 28;13:1755-1765. Epub 2018 May 28.

Division of Molecular and Clinical Medicine, Medical Research Institute, University of Dundee, Dundee, UK.

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May 2018

Effects of contrast administration on cardiac MRI volumetric, flow and pulse wave velocity quantification using manual and software-based analysis.

Br J Radiol 2018 Apr 19;91(1084):20170717. Epub 2018 Jan 19.

1 Division of Molecular and Clinical Medicine, Medical Research Institute, University of Dundee , Dundee , UK.

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April 2018

The APEX trial: Effects of allopurinol on exercise capacity, coronary and peripheral endothelial function, and natriuretic peptides in patients with cardiac syndrome X.

Cardiovasc Ther 2018 Feb 26;36(1). Epub 2017 Nov 26.

Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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February 2018

Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling.

Eur Radiol 2018 Feb 27. Epub 2018 Feb 27.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, UK.

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February 2018

An Open-Label Dose-Finding Study of Allopurinol to Target Defined Reduction in Urate Levels in Hemodialysis Patients.

J Clin Pharmacol 2017 Nov 9;57(11):1409-1414. Epub 2017 Jun 9.

Division of Molecular & Clinical Medicine, School of Medicine, Ninewells Hospital and Medical School, Dundee, UK.

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November 2017

Association between GDF-15 levels and changes in vascular and physical function in older patients with hypertension.

Aging Clin Exp Res 2017 Oct 12;29(5):1055-1059. Epub 2016 Oct 12.

Division of Cardiovascular and Diabetes Medicine, University of Dundee, Dundee, UK.

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October 2017

Twenty-Year Predictors of Peripheral Arterial Disease Compared With Coronary Heart Disease in the Scottish Heart Health Extended Cohort (SHHEC).

J Am Heart Assoc 2017 Sep 18;6(9). Epub 2017 Sep 18.

Vascular Medicine, Institute of Cardiovascular Research, University of Dundee, United Kingdom.

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September 2017

Does dapagliflozin regress left ventricular hypertrophy in patients with type 2 diabetes? A prospective, double-blind, randomised, placebo-controlled study.

BMC Cardiovasc Disord 2017 08 23;17(1):229. Epub 2017 Aug 23.

Cardiovascular Medicine and Therapeutics, Division of Molecular and Clinical Medicine, Medical Research Institute, Ninewells Hospital and Medical School, Mailbox 2, Dundee, DD1 9SY, UK.

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August 2017

Research cardiac magnetic resonance imaging in end stage renal disease - incidence, significance and implications of unexpected incidental findings.

Eur Radiol 2017 Jan 7;27(1):315-324. Epub 2016 Apr 7.

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Building, Glasgow Clinical Research Centre, Glasgow, G12 8TA, UK.

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January 2017

The Incidence and Risk of Biochemical Recurrence Following Radical Radiotherapy for Prostate Cancer in Men on Angiotensin-Converting Enzyme Inhibitors (ACEIs) or Angiotensin Receptor Blockers (ARBs).

Clin Genitourin Cancer 2016 10 12;14(5):398-405. Epub 2016 Mar 12.

Academic Section of Urology, Division of Cancer Research, School of Medicine, University of Dundee, Scotland.

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October 2016

Assessment of proximal pulmonary arterial stiffness using magnetic resonance imaging: effects of technique, age and exercise.

BMJ Open Respir Res 2016 7;3(1):e000149. Epub 2016 Oct 7.

Division of Cardiovascular and Diabetes Medicine , Medical Research Institute, University of Dundee , Dundee , UK.

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October 2016

Multicentre, prospective, randomised, open-label, blinded end point trial of the efficacy of allopurinol therapy in improving cardiovascular outcomes in patients with ischaemic heart disease: protocol of the ALL-HEART study.

BMJ Open 2016 09 8;6(9):e013774. Epub 2016 Sep 8.

Medicines Monitoring Unit (MEMO) and Hypertension Research Centre, Division of Molecular and Clinical Medicine, University of Dundee and Ninewells Hospital, Dundee, UK.

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September 2016

Aortic remodelling following the treatment and regression of hypertensive left ventricular hypertrophy: a cardiovascular magnetic resonance study.

Clin Exp Hypertens 2015 1;37(4):308-16. Epub 2014 Oct 1.

Multidisciplinary Cardiovascular Research Centre (MCRC) & Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds , Leeds , UK .

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August 2016

Research into the effect Of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus (REFORM) trial rationale and design.

Cardiovasc Diabetol 2016 Jul 15;15:97. Epub 2016 Jul 15.

Division of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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July 2016

Follow-up of atheroma burden with sequential whole body contrast enhanced MR angiography: a feasibility study.

Int J Cardiovasc Imaging 2016 May 25;32(5):825-32. Epub 2016 Jan 25.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, DD1 9SY, UK.

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May 2016

Letter to the editor: Comparing pace and speed in the pulmonary circulation?

Am J Physiol Heart Circ Physiol 2016 Apr;310(7):H949

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, United Kingdom; and.

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April 2016

A Randomized Controlled Trial of Allopurinol in Patients With Peripheral Arterial Disease.

Can J Cardiol 2016 02 19;32(2):190-6. Epub 2015 May 19.

Division of Cardiovascular and Diabetes Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.

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February 2016

Mean HbA1c and mortality in diabetic individuals with heart failure: a population cohort study.

Eur J Heart Fail 2016 Jan 13;18(1):94-102. Epub 2015 Dec 13.

Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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January 2016

The role of pulmonary arterial stiffness in COPD.

Respir Med 2015 Nov 12;109(11):1381-90. Epub 2015 Jun 12.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, United Kingdom.

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November 2015

High B-Type Natriuretic Peptide Hypertensives at Target Blood Pressure: Potential Role of β-Blockers to Reduce Their Elevated Risk.

Hypertension 2015 Nov 21;66(5):927-32. Epub 2015 Sep 21.

From the Division of Cardiovascular and Diabetes Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland.

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November 2015

Common carotid intima media thickness and ankle-brachial pressure index correlate with local but not global atheroma burden: a cross sectional study using whole body magnetic resonance angiography.

PLoS One 2014 16;9(6):e99190. Epub 2014 Jun 16.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Dundee, United Kingdom; NHS Tayside Clinical Radiology, Ninewells Hospital, Dundee, United Kingdom.

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October 2015

Impact of Left Ventricular Hypertrophy on Survival in Chronic Obstructive Pulmonary Disease.

Lung 2015 Aug 29;193(4):487-95. Epub 2015 Mar 29.

Scottish Centre for Respiratory Research, Cardiovascular & Diabetes Medicine, Medical Research Institute, Ninewells Hospital, University of Dundee, Dundee, DD1 9SY, Scotland, UK.

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August 2015

Both high and low HbA1c predict incident heart failure in type 2 diabetes mellitus.

Circ Heart Fail 2015 Mar 5;8(2):236-42. Epub 2015 Jan 5.

From the Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital, University of Dundee, Dundee, United Kingdom.

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March 2015

An increased B-type natriuretic peptide in the absence of a cardiac abnormality identifies those whose left ventricular mass will increase over time.

JACC Heart Fail 2015 Jan 11;3(1):87-93. Epub 2014 Nov 11.

Division of Cardiovascular & Diabetes Medicine, Medical Research Institute, Ninewells Hospital, Dundee, Scotland, United Kingdom.

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January 2015

Effect of vitamin D supplementation on orthostatic hypotension: data from the vitamin D in isolated systolic hypertension randomized controlled trial.

J Hypertens 2014 Aug;32(8):1693-9; discussion 1699

aAgeing and Health bDepartment of Clinical Pharmacology cEpidemiology and Biostatistics Unit dRobertson Centre for Biostatistics, University of Dundee, Dundee, UK.

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August 2014

Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial.

J Gerontol A Biol Sci Med Sci 2014 Jun 7;69(6):736-43. Epub 2013 Nov 7.

Division of Cardiovascular and Diabetes Medicine, University of Dundee, UK.

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June 2014

High-potency statin and ezetimibe use and mortality in survivors of an acute myocardial infarction: a population-based study.

Heart 2014 Jun 19;100(11):867-72. Epub 2014 Feb 19.

Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, University of Dundee, , Dundee, UK.

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June 2014

Vitamin D therapy to reduce blood pressure and left ventricular hypertrophy in resistant hypertension: randomized, controlled trial.

Hypertension 2014 Apr 13;63(4):706-12. Epub 2014 Jan 13.

Ageing and Health, Ninewells Hospital, University of Dundee, Dundee DD1 9SY, United Kingdom.

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April 2014

Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial.

Lancet Respir Med 2014 Apr 5;2(4):293-300. Epub 2014 Mar 5.

Division of Cardiovascular and Diabetes Medicine, University of Dundee, Dundee, Scotland, UK.

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April 2014

Myocardial ischaemia is associated with an elevated brain natriuretic pepide level even in the presence of left ventricular systolic dysfunction.

Eur J Heart Fail 2014 Jan 3;16(1):56-67. Epub 2013 Dec 3.

Division of Cardiovascular and Diabetes Medicine, University of Dundee, Dundee, UK.

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January 2014

Allopurinol reduces left ventricular mass in patients with type 2 diabetes and left ventricular hypertrophy.

J Am Coll Cardiol 2013 Dec 28;62(24):2284-93. Epub 2013 Aug 28.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.

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December 2013

Pentaerythrityl tetranitrate (PETN): a better nitrate?

Eur Heart J 2013 Oct 14. Epub 2013 Oct 14.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, Ninewells Hospital, Dundee SS1 9SY, UK.

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October 2013

Effects of vitamin D supplementation on markers of vascular function after myocardial infarction--a randomised controlled trial.

Int J Cardiol 2013 Aug 28;167(3):745-9. Epub 2012 Mar 28.

Ageing and Health, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, United Kingdom.

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August 2013

A new approach to residual risk in treated hypertension--3P screening.

Hypertension 2013 Aug 17;62(2):236-9. Epub 2013 Jun 17.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom.

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August 2013

Effect of spironolactone on physical performance in older people with self-reported physical disability.

Am J Med 2013 Jul 23;126(7):590-7. Epub 2013 May 23.

Ageing and Health, Medical Research Institute, Division of Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, University of Dundee, United Kingdom.

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July 2013

Targeting the renin-angiotensin-aldosterone system in heart failure.

Nat Rev Cardiol 2013 Mar 15;10(3):125-34. Epub 2013 Jan 15.

Division of Cardiovascular & Diabetes Medicine, MailBox 2, Ninewells Hospital and Medical School, Medical Research Institute, University of Dundee, Dundee DD1 9SY, UK.

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March 2013

High-dose allopurinol reduces left ventricular mass in patients with ischemic heart disease.

J Am Coll Cardiol 2013 Mar;61(9):926-32

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, United Kingdom.

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March 2013

Left ventricular hypertrophy in COPD without hypoxemia: the elephant in the room?

Chest 2013 Jan;143(1):91-97

Centre for Cardiovascular and Lung Biology, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland. Electronic address:

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January 2013

Aortic valvular heart disease: Is there a place for angiotensin-converting-enzyme inhibitors?

Expert Rev Cardiovasc Ther 2013 Jan;11(1):107-14

Division of Cardiovascular and Diabetes Medicine, College of Medicine, Dentistry and Nursing, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.

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January 2013

The effect of metformin on insulin resistance and exercise parameters in patients with heart failure.

Eur J Heart Fail 2012 Nov 27;14(11):1303-10. Epub 2012 Jun 27.

Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Ninewells Hospital & Medical School, UK.

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November 2012

Allopurinol: novel indications in cardiovascular disease.

Heart 2012 Nov 16;98(21):1543-5. Epub 2012 Jul 16.

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November 2012

Insulin sensitization therapy and the heart: focus on metformin and thiazolidinediones.

Heart Fail Clin 2012 Oct 9;8(4):539-50. Epub 2012 Aug 9.

Division of Cardiovascular and Diabetes Medicine, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom.

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October 2012

B-type natriuretic peptide is an independent predictor of endothelial function in man.

Clin Sci (Lond) 2012 Sep;123(5):307-12

Centre for Cardiovascular and Lung Biology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, UK.

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September 2012

Improving the primary prevention of cardiovascular events by using biomarkers to identify individuals with silent heart disease.

J Am Coll Cardiol 2012 Sep 22;60(11):960-8. Epub 2012 Aug 22.

Centre for Cardiovascular and Lung Biology, University of Dundee, United Kingdom.

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September 2012

The prognostic value of high sensitivity troponin T 7 weeks after an acute coronary syndrome.

Heart 2012 Aug 11;98(15):1160-5. Epub 2012 Jun 11.

Centre for Cardiovascular and Lung Biology, University of Dundee, Ninewells Hospital & Medical School, Dundee, UK.

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August 2012

Renin-angiotensin system blockers are associated with reduced mortality and heart failure hospitalization in patients paced for complete atrioventricular block.

Heart Rhythm 2012 Apr 15;9(4):505-10. Epub 2011 Nov 15.

Centre for Cardiovascular and Diabetes Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, UK.

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April 2012

Efficacy and cost of an exercise program for functionally impaired older patients with heart failure: a randomized controlled trial.

Circ Heart Fail 2012 Mar 23;5(2):209-16. Epub 2012 Jan 23.

Ageing and Health and Department of Clinical Pharmacology, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Dundee, UK.

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March 2012

Pulmonary hypertension predicts all-cause mortality in patients with heart failure: a retrospective cohort study.

Eur J Heart Fail 2012 Feb 16;14(2):162-7. Epub 2011 Dec 16.

Centre for Cardiovascular and Lung Biology, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.

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February 2012

Mineralocorticoid antagonism: a novel way to treat sarcopenia and physical impairment in older people?

Clin Endocrinol (Oxf) 2011 Dec;75(6):725-9

Section of Ageing and Health, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.

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December 2011

Impact of renin-angiotensin system blockade therapy on outcome in aortic stenosis.

J Am Coll Cardiol 2011 Aug;58(6):570-6

Centre for Cardiovascular and Lung Biology, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom.

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August 2011

Mechanistic insights into the therapeutic use of high-dose allopurinol in angina pectoris.

J Am Coll Cardiol 2011 Aug;58(8):820-8

Division of Medical Sciences, University of Dundee, Ninewells Hospital Medical School, Dundee, UK.

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August 2011

The role of urate and xanthine oxidase in vascular oxidative stress: future directions.

Ther Clin Risk Manag 2009 12;5:799-803. Epub 2009 Oct 12.

Division of Medicine and Therapeutics, Ninewells Hospital and Medical School, Dundee, UK.

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July 2011

Allopurinol benefits left ventricular mass and endothelial dysfunction in chronic kidney disease.

J Am Soc Nephrol 2011 Jul 30;22(7):1382-9. Epub 2011 Jun 30.

Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, United Kingdom.

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July 2011

Right ventricular pacing impairs endothelial function in man.

Europace 2011 Jun 22;13(6):853-8. Epub 2011 Feb 22.

Centre for Cardiovascular and Lung Biology, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.

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June 2011

Family history of premature coronary heart disease and risk prediction.

Heart 2011 Apr 1;97(8):684; author reply 684. Epub 2011 Mar 1.

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April 2011

Impact of allopurinol use on urate concentration and cardiovascular outcome.

Br J Clin Pharmacol 2011 Apr;71(4):600-7

Medicines Monitoring Unit (MEMO), Division of Medical Sciences, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.

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April 2011

Meta-analysis of B-type natriuretic peptide's ability to identify stress induced myocardial ischemia.

Am J Cardiol 2011 Mar 22;107(5):662-7. Epub 2010 Dec 22.

Department of Clinical Pharmacology, University of Dundee, Dundee, UK.

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March 2011

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial.

Lancet 2010 Jun 9;375(9732):2161-7. Epub 2010 Jun 9.

Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.

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June 2010

Spironolactone use and renal toxicity: population based longitudinal analysis.

BMJ 2010 May 18;340:c1768. Epub 2010 May 18.

Medicines Monitoring Unit (MEMO), Division of Medical Sciences, Ninewells Hospital and Medical School, Dundee DD1 9SY.

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May 2010

The effects of vitamin D supplementation on physical function and quality of life in older patients with heart failure: a randomized controlled trial.

Circ Heart Fail 2010 Mar 26;3(2):195-201. Epub 2010 Jan 26.

Section of Ageing and Health and Department of Clinical Pharmacology, Division of Medicine, Centre for Cardiovascular and Lung Biology, University of Dundee, Ninewells Hospital, Dundee, United Kingdom.

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March 2010

Heart rate variability as an indicator of left ventricular systolic dysfunction.

Cardiovasc J Afr 2009 Sep-Oct;20(5):278-83

Department of Internal Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University.

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January 2010

Effect of vitamin D on blood pressure: a systematic review and meta-analysis.

J Hypertens 2009 Oct;27(10):1948-54

Section of Ageing and Health, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland.

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October 2009

Serial bedside B-type natriuretic peptide strongly predicts prognosis in acute coronary syndrome independent of echocardiographic abnormalities.

Am Heart J 2009 Jul;158(1):133-40

Division of Medicine and Therapeutics, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK.

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July 2009