Allan Saul

Impact of Victoria's Stage 3 lockdown on COVID-19 case numbers.

Authors:

Allan Saul Nick Scott Brendan S Crabb Suman S Majumdar Benjamin Coghlan Margaret E Hellard

Med J Aust 2020 12 23;213(11):494-496.e1. Epub 2020 Nov 23.

Burnet Institute, Melbourne, VIC.

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December 2020

Rational Design of a Glycoconjugate Vaccine against Group A .

Authors:

Roberta Di Benedetto Francesca Mancini Martina Carducci Gianmarco Gasperini Danilo Gomes Moriel Allan Saul Francesca Necchi Rino Rappuoli Francesca Micoli

Int J Mol Sci 2020 Nov 13;21(22). Epub 2020 Nov 13.

GSK Vaccines Institute for Global Health (GVGH), Via Fiorentina 1, 53100 Siena, Italy.

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November 2020

GMMA Is a Versatile Platform to Design Effective Multivalent Combination Vaccines.

Authors:

Francesca Micoli Renzo Alfini Roberta Di Benedetto Francesca Necchi Fabiola Schiavo Francesca Mancini Martina Carducci Elena Palmieri Cristiana Balocchi Gianmarco Gasperini Brunella Brunelli Paolo Costantino Roberto Adamo Diego Piccioli Allan Saul

Vaccines (Basel) 2020 Sep 17;8(3). Epub 2020 Sep 17.

GSK Vaccines Institute for Global Health (GVGH) S.r.l., 53100 Siena, Italy.

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September 2020

Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM conjugate vaccine.

Authors:

Francesca Micoli Stefania P Bjarnarson Melissa Arcuri Audur Anna Aradottir Pind Gudbjorg J Magnusdottir Francesca Necchi Roberta Di Benedetto Martina Carducci Fabiola Schiavo Carlo Giannelli Ivan Pisoni Laura B Martin Giuseppe Del Giudice Calman A MacLennan Rino Rappuoli Ingileif Jonsdottir Allan Saul

Proc Natl Acad Sci U S A 2020 09 8;117(39):24443-24449. Epub 2020 Sep 8.

Technology Platform Unit, GSK Vaccines Institute for Global Health (GVGH), 53100 Siena, Italy.

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September 2020

Intra-Laboratory Evaluation of Luminescence Based High-Throughput Serum Bactericidal Assay (L-SBA) to Determine Bactericidal Activity of Human Sera against .

Authors:

Omar Rossi Eleonora Molesti Allan Saul Carlo Giannelli Francesca Micoli Francesca Necchi

High Throughput 2020 Jun 8;9(2). Epub 2020 Jun 8.

GSK Vaccines Institute for Global Health s.r.l (GVGH), Siena 53100, Italy.

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June 2020

The use and abuse of a 4-fold increase in antibody response to assess immunogenicity in early stage vaccine clinical trials.

Authors:

Allan Saul Audino Podda Rino Rappuoli

Vaccine 2020 01 9;38(5):951-953. Epub 2019 Dec 9.

GSK, Siena, Italy.

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January 2020

Author Correction: Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Nat Genet 2019 Aug;51(8):1295

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.

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August 2019

Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics.

Nat Genet 2019 06 27;51(6):1035-1043. Epub 2019 May 27.

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia.

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June 2019

Development of FAcE (Formulated Alhydrogel competitive ELISA) method for direct quantification of OAg present in Shigella sonnei GMMA-based vaccine and its optimization using Design of Experiments approach.

Authors:

Francesca Necchi Martina Carducci Ivan Pisoni Omar Rossi Allan Saul Simona Rondini

J Immunol Methods 2019 08 27;471:11-17. Epub 2019 Apr 27.

GSK Vaccines Institute for Global Health (GVGH) S.r.l., Siena, Italy. Electronic address:

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August 2019

Booster Vaccination With GVGH 1790GAHB GMMA Vaccine Compared to Single Vaccination in Unvaccinated Healthy European Adults: Results From a Phase 1 Clinical Trial.

Authors:

Odile Launay Augustin G W Ndiaye Valentino Conti Pierre Loulergue Antonella Silvia Sciré Anais Maugard Landre Pietro Ferruzzi Naouel Nedjaai Lena Dorothee Schütte Joachim Auerbach Elisa Marchetti Allan Saul Laura B Martin Audino Podda

Front Immunol 2019 8;10:335. Epub 2019 Mar 8.

GSK Vaccines Institute for Global Health, Siena, Italy.

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September 2020

Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal .

Authors:

Francesca Micoli Simona Rondini Renzo Alfini Luisa Lanzilao Francesca Necchi Aurel Negrea Omar Rossi Cornelia Brandt Simon Clare Pietro Mastroeni Rino Rappuoli Allan Saul Calman A MacLennan

Proc Natl Acad Sci U S A 2018 10 27;115(41):10428-10433. Epub 2018 Sep 27.

Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom.

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October 2018

Setup of luminescence-based serum bactericidal assay against Salmonella Paratyphi A.

Authors:

Francesca Necchi Allan Saul Simona Rondini

J Immunol Methods 2018 10 30;461:117-121. Epub 2018 Jun 30.

GSK Vaccines Institute for Global Health (GVGH) S.r.l., via Fiorentina 1, 53100 Siena, Italy.

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October 2018

A Phase 2a Randomized Study to Evaluate the Safety and Immunogenicity of the 1790GAHB Generalized Modules for Membrane Antigen Vaccine against Administered Intramuscularly to Adults from a Shigellosis-Endemic Country.

Authors:

Christina W Obiero Augustin G W Ndiaye Antonella Silvia Sciré Bonface M Kaunyangi Elisa Marchetti Ann M Gone Lena Dorothee Schütte Daniele Riccucci Joachim Auerbach Allan Saul Laura B Martin Philip Bejon Patricia Njuguna Audino Podda

Front Immunol 2017 22;8:1884. Epub 2017 Dec 22.

GSK Vaccines Institute for Global Health, Siena, Italy.

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December 2017

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1.

Authors:

Arianna Marini Omar Rossi Maria Grazia Aruta Francesca Micoli Simona Rondini Serafina Guadagnuolo Isabel Delany Ian R Henderson Adam F Cunningham Allan Saul Calman A MacLennan Oliver Koeberling

PLoS One 2017 25;12(7):e0181508. Epub 2017 Jul 25.

GSK Vaccines Institute for Global Health (GVGH), Siena, Italy.

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October 2017

Safety Profile and Immunologic Responses of a Novel Vaccine Against Shigella sonnei Administered Intramuscularly, Intradermally and Intranasally: Results From Two Parallel Randomized Phase 1 Clinical Studies in Healthy Adult Volunteers in Europe.

Authors:

Odile Launay David J M Lewis Alessandra Anemona Pierre Loulergue Jo Leahy Antonella Silvia Sciré Anaïs Maugard Elisa Marchetti Stefano Zancan Zhiming Huo Simona Rondini Rachid Marhaba Oretta Finco Laura B Martin Jochen Auerbach Daniel Cohen Allan Saul Christiane Gerke Audino Podda

EBioMedicine 2017 Aug 15;22:164-172. Epub 2017 Jul 15.

GSK Vaccines Institute for Global Health, Siena, Italy. Electronic address:

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August 2017

Development of a high-throughput method to evaluate serum bactericidal activity using bacterial ATP measurement as survival readout.

Authors:

Francesca Necchi Allan Saul Simona Rondini

PLoS One 2017 13;12(2):e0172163. Epub 2017 Feb 13.

GSK Vaccines Institute for Global Health (GVGH) S.r.l., Siena, Italy.

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August 2017

A Systematic Review of the Incidence, Risk Factors and Case Fatality Rates of Invasive Nontyphoidal Salmonella (iNTS) Disease in Africa (1966 to 2014).

Authors:

Ifeanyi Valentine Uche Calman A MacLennan Allan Saul

PLoS Negl Trop Dis 2017 01 5;11(1):e0005118. Epub 2017 Jan 5.

Novartis Vaccines Institute for Global Health, Siena, Italy.

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January 2017

Prioritizing vaccines for developing world diseases.

Authors:

Allan Saul Katherine L O'Brien

Vaccine 2017 01 22;35 Suppl 1:A16-A19. Epub 2016 Dec 22.

International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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January 2017

Neutropenia as an Adverse Event following Vaccination: Results from Randomized Clinical Trials in Healthy Adults and Systematic Review.

Authors:

Vincent Muturi-Kioi David Lewis Odile Launay Geert Leroux-Roels Alessandra Anemona Pierre Loulergue Caroline L Bodinham Annelies Aerssens Nicola Groth Allan Saul Audino Podda

PLoS One 2016 4;11(8):e0157385. Epub 2016 Aug 4.

Novartis Vaccines Institute for Global Health, Siena, Italy.

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August 2017

Bactericidal Immunity to Salmonella in Africans and Mechanisms Causing Its Failure in HIV Infection.

Authors:

Yun Shan Goh Francesca Necchi Colette M O'Shaughnessy Francesca Micoli Massimiliano Gavini Stephen P Young Chisomo L Msefula Esther N Gondwe Wilson L Mandala Melita A Gordon Allan J Saul Calman A MacLennan

PLoS Negl Trop Dis 2016 Apr 8;10(4):e0004604. Epub 2016 Apr 8.

School of Immunity and Infection, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.

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April 2016

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