Allan J Zajac

Allan J Zajac

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Allan J Zajac

Allan J Zajac

Publications by authors named "Allan J Zajac"

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IL-21 Controls ILC3 Cytokine Production and Promotes a Protective Phenotype in a Mouse Model of Colitis.

Immunohorizons 2019 06 4;3(6):194-202. Epub 2019 Jun 4.

Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294; and

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http://dx.doi.org/10.4049/immunohorizons.1900005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788290PMC
June 2019

Inscribing the core memories of killers.

Cell Mol Immunol 2019 02 7;16(2):104-105. Epub 2018 Nov 7.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, 35294, United States.

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http://dx.doi.org/10.1038/s41423-018-0178-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355866PMC
February 2019

Immune Exhaustion: Past Lessons and New Insights from Lymphocytic Choriomeningitis Virus.

Viruses 2019 02 13;11(2). Epub 2019 Feb 13.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.3390/v11020156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410286PMC
February 2019

Late arising T follicular helper cells cultivate the B cell crop during chronic infections.

Sci Immunol 2017 12;2(18)

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294-2170, USA.

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http://dx.doi.org/10.1126/sciimmunol.aap9339DOI Listing
December 2017

Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection.

Nat Immunol 2017 Nov 11;18(11):1249-1260. Epub 2017 Sep 11.

Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Alabama, USA.

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http://dx.doi.org/10.1038/ni.3837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679073PMC
November 2017

IL-21 and T Cell Differentiation: Consider the Context.

Trends Immunol 2016 08 4;37(8):557-568. Epub 2016 Jul 4.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294-2170, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2016.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969098PMC
August 2016

Editorial overview: Viral immunology.

Curr Opin Virol 2016 Feb 12;16:vii-ix. Epub 2016 Mar 12.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coviro.2016.01.012DOI Listing
February 2016

A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control.

Cell Rep 2015 Nov 29;13(6):1118-1124. Epub 2015 Oct 29.

Blood Research Institute, BloodCenter of Wisconsin, 8727 West Watertown Plank Road, Milwaukee, WI 53213, USA; Department of Microbiology and Molecular Genetics, Medical College of Wisconsin, 8701 West Watertown Plank Road, Milwaukee, WI 53226, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.09.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859432PMC
November 2015

T cell exhaustion during persistent viral infections.

Virology 2015 May 22;479-480:180-93. Epub 2015 Jan 22.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2014.12.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424083PMC
May 2015

A stay of execution: type I interferons pardon T cells from death by natural killers.

Immunity 2014 Jun;40(6):861-2

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2014.05.009DOI Listing
June 2014

Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors.

J Leukoc Biol 2014 05 14;95(5):705-713. Epub 2013 Nov 14.

Departments of Cell, Developmental, and Integrative Biology,

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http://dx.doi.org/10.1189/jlb.0813429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984968PMC
May 2014

Tissue-resident T cells lose their S1P1 exit visas.

Cell Mol Immunol 2014 May 24;11(3):221-3. Epub 2014 Feb 24.

Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL, 35294 United States.

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http://dx.doi.org/10.1038/cmi.2014.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085496PMC
May 2014

Temporal requirements for B cells in the establishment of CD4 T cell memory.

J Immunol 2013 Dec 11;191(12):6052-9. Epub 2013 Nov 11.

Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294.

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http://dx.doi.org/10.4049/jimmunol.1302033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866023PMC
December 2013

IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis.

J Neuroimmunol 2013 Oct 6;263(1-2):43-54. Epub 2013 Aug 6.

Department of Neurosciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2013.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3796038PMC
October 2013

Anti-viral CD8 T cells and the cytokines that they love.

Virology 2013 Jan;435(1):157-69

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1016/j.virol.2012.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580945PMC
January 2013

ICAM-1-dependent tuning of memory CD8 T-cell responses following acute infection.

Proc Natl Acad Sci U S A 2013 Jan 7;110(4):1416-21. Epub 2013 Jan 7.

Departments of Microbiology and Genetics, University of Alabama, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1073/pnas.1213480110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557037PMC
January 2013

Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections.

PLoS Pathog 2011 Sep 29;7(9):e1002273. Epub 2011 Sep 29.

Department of Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182940PMC
September 2011

Cytokines and the inception of CD8 T cell responses.

Trends Immunol 2011 Apr 2;32(4):180-6. Epub 2011 Mar 2.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, United States.

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http://dx.doi.org/10.1016/j.it.2011.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074938PMC
April 2011

Interleukin-21: a multifunctional regulator of immunity to infections.

Microbes Infect 2010 Dec 9;12(14-15):1111-9. Epub 2010 Sep 9.

Department of Microbiology, University of Alabama at Birmingham, 845 19th Street South, BBRB 446; Box 23, Birmingham, AL 35294-2170, USA.

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http://dx.doi.org/10.1016/j.micinf.2010.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998550PMC
December 2010

IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection.

J Immunol 2010 Oct 15;185(8):4835-45. Epub 2010 Sep 15.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.4049/jimmunol.1001032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950881PMC
October 2010

Shaping successful and unsuccessful CD8 T cell responses following infection.

J Biomed Biotechnol 2010 31;2010:159152. Epub 2010 Mar 31.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1155/2010/159152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850140PMC
September 2010

Pronounced virus-dependent activation drives exhaustion but sustains IFN-γ transcript levels.

J Immunol 2010 Sep 18;185(6):3643-51. Epub 2010 Aug 18.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.4049/jimmunol.1000841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933304PMC
September 2010

T-cell exhaustion: characteristics, causes and conversion.

Immunology 2010 Apr 23;129(4):474-81. Epub 2010 Feb 23.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1111/j.1365-2567.2010.03255.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842494PMC
April 2010

A vital role for interleukin-21 in the control of a chronic viral infection.

Science 2009 Jun 14;324(5934):1572-6. Epub 2009 May 14.

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294-2170, USA.

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http://dx.doi.org/10.1126/science.1175194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736049PMC
June 2009

Memory CD4 T cells emerge from effector T-cell progenitors.

Nature 2008 Mar 5;452(7185):356-60. Epub 2008 Mar 5.

Department of Pathology, University of Alabama at Birmingham, 845 19th Street South, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1038/nature06672DOI Listing
March 2008

Functionally competent antigen-specific CD127(hi) memory CD8+ T cells are preserved only in HIV-infected individuals receiving early treatment.

J Infect Dis 2007 Jan 20;195(1):108-17. Epub 2006 Nov 20.

Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1086/509510DOI Listing
January 2007

Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory.

Eur J Immunol 2006 Jul;36(7):1694-706

Division of Immunobiology, Cincinnati Children's Hospital and the University of Cincinnati, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1002/eji.200635897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222686PMC
July 2006

In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin.

Hum Gene Ther 2006 Jun;17(6):669-82

Department of Medicine, University of Alabama at Birmingham, and Veterans Administration Medical Center, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1089/hum.2006.17.669DOI Listing
June 2006

Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections.

J Immunol 2004 Apr;172(7):4204-14

Department of Microbiology, University of Alabama, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.4049/jimmunol.172.7.4204DOI Listing
April 2004

CD4 T cell-dependent CD8 T cell maturation.

J Immunol 2004 Mar;172(5):2834-44

Department of Microbiology, University of Alabama, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.4049/jimmunol.172.5.2834DOI Listing
March 2004

T cell responses to viral infections: lessons from lymphocytic choriomeningitis virus.

Immunol Res 2002 ;26(1-3):309-21

Department of Microbiology, University of Alabama at Birmingham, 35294-2170, USA.

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http://dx.doi.org/10.1385/IR:26:1-3:309DOI Listing
April 2003

Ablation of CD8 and CD4 T cell responses by high viral loads.

J Immunol 2003 Jan;170(1):477-86

Department of Microbiology, University of Alabama, Birmingham, AL 35294-2170, USA.

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http://dx.doi.org/10.4049/jimmunol.170.1.477DOI Listing
January 2003

Control of lymphocytic choriomeningitis virus infection in granzyme B deficient mice.

Virology 2003 Jan;305(1):1-9

Department of Microbiology and Immunology, Loyola University Chicago, Maywood, Illinois 60153, USA.

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http://dx.doi.org/10.1006/viro.2002.1754DOI Listing
January 2003

Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells.

J Immunol 2002 Aug;169(3):1444-52

Department of Molecular and Cell Biology and Cancer Research Laboratory, University of California, Berkeley, CA 94720, USA.

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http://dx.doi.org/10.4049/jimmunol.169.3.1444DOI Listing
August 2002