Allan Doctor

Allan Doctor

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Effect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial.

JAMA 2019 12;322(22):2179-2190

Research CHU de Québec-Université Laval Centre, Population Health and Optimal Health Practices and Research Unit, Trauma, Emergency, Critical Care Medicine, Université Laval and Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Faculty of Medicine, Université Laval, Québec City, Québec, Canada.

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http://dx.doi.org/10.1001/jama.2019.17478DOI Listing
December 2019

Effect of plasma processing and storage on microparticle abundance, nitric oxide scavenging, and vasoactivity.

Transfusion 2019 04;59(S2):1568-1577

Department of Pediatrics, Divisions of Critical Care Medicine, Washington University in Saint Louis, School of Medicine, Saint Louis, Missouri.

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http://dx.doi.org/10.1111/trf.15214DOI Listing
April 2019

Implementation of the Recommendations for RBC Transfusions for Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative.

Pediatr Crit Care Med 2018 09;19(9S Suppl 1):S170-S176

Division of Pediatric Critical Care Medicine, Department of Pediatrics, St. Louis Children's Hospital, Washington University School of Medicine in St. Louis, St. Louis, MO.

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http://dx.doi.org/10.1097/PCC.0000000000001592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124312PMC
September 2018

How to Push the Limit: Developing Informed Research and Implementation Programs in Resource-Limited Settings.

Pediatr Crit Care Med 2018 07;19(7):680-681

Division of Pediatric Critical Care, Department of Pediatrics, Washington University in St. Louis, St. Louis, MO.

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http://dx.doi.org/10.1097/PCC.0000000000001565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042976PMC
July 2018

Development of a Structured Outcomes Assessment and Implementation Program in the Pediatric Intensive Care Unit.

Am J Med Qual 2019 Jan/Feb;34(1):23-29. Epub 2018 Jul 16.

2 St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1177/1062860618788173DOI Listing
July 2018

Reduction in Mortality Following Pediatric Rapid Response Team Implementation.

Pediatr Crit Care Med 2018 05;19(5):477-482

Department of Pediatric, Washington University in St. Louis, St. Louis, MO.

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http://dx.doi.org/10.1097/PCC.0000000000001519DOI Listing
May 2018

Design, synthesis, and biological evaluation of stable β-Helices: Discovery of non-hemolytic antibacterial peptides.

Eur J Med Chem 2018 Apr 20;149:193-210. Epub 2018 Feb 20.

Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2018.02.057DOI Listing
April 2018

Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease.

Neurology 2018 03 2;90(13):e1134-e1142. Epub 2018 Mar 2.

From the Division of Pediatric Hematology/Oncology (M.E.F., M.L.H.), Division of Pediatric Neurology (K.P.G.), Division of Pediatric Critical Care Medicine (K.P.G., A.D.), Department of Neurology (D.K.R., Y.C., A.L.F., J.-M.L.), and Mallinckrodt Institute of Radiology (C.E., R.C.M., J.S.S., K.D.V., H.A., J.-M.L.), Washington University School of Medicine; and Department of Biomedical Engineering (M.B.M., J.-M.L.), Washington University, St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000005194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880632PMC
March 2018

Physiologic Impact of Circulating RBC Microparticles upon Blood-Vascular Interactions.

Front Physiol 2017 12;8:1120. Epub 2018 Jan 12.

Department of Pediatrics, Washington University in St. Louis, St. Louis, MO, United States.

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http://dx.doi.org/10.3389/fphys.2017.01120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770796PMC
January 2018

Potential Acceptability of a Pediatric Ventilator Management Computer Protocol.

Pediatr Crit Care Med 2017 Nov;18(11):1027-1034

1University of Utah College of Nursing, Salt Lake City, UT. 2Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT. 3Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 4Department of Pediatrics, University of Southern California, Keck School of Medicine, Los Angeles, CA. 5Division of Pediatric Critical Care, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT. 6Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 7Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 8Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL. 9Department of Pediatrics, University of Michigan, Ann Arbor, MI. 10Department of Pediatrics, Children's National Medical Center, Washington, DC. 11Department of Child Health, Phoenix Children's Hospital, Phoenix, AZ. 12Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 13Department of Pediatrics, Mattel Children's Hospital UCLA, Los Angeles, CA. 14Departments of Pediatrics and Biochemistry, Washington University School of Medicine, St. Louis, MO. 15Pediatric Trauma and Critical Injury Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD. 16Formerly Pediatric Trauma and Critical Injury Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/PCC.0000000000001331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108591PMC
November 2017

Variability in Usual Care Mechanical Ventilation for Pediatric Acute Respiratory Distress Syndrome: Time for a Decision Support Protocol?

Pediatr Crit Care Med 2017 Nov;18(11):e521-e529

1Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 2Department of Pediatrics, University of Southern California, Keck School of Medicine, Los Angeles, CA. 3University of Utah College of Nursing, Salt Lake City, UT. 4Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, UT. 5Department of Pediatrics, Division of Pediatric Critical Care, University of Utah School of Medicine, Salt Lake City, UT. 6Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 7Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 8Department of Pediatrics, University of Michigan, Ann Arbor, MI. 9Department of Child Health, Phoenix Children's Hospital, Phoenix, AZ. 10Department of Pediatrics, Children's National Medical Center, Washington, DC. 11Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 12Department of Pediatrics, Mattel Children's Hospital, UCLA, Los Angeles, CA. 13Departments of Pediatrics and Biochemistry, Washington University School of Medicine, St. Louis, MO. 14Pediatric Trauma and Critical Illness Branch, National Institutes of Child Health and Human Development (NICHD), Bethesda, MD. 15Formerly Pediatric Trauma and Critical Illness Branch, National Institutes of Child Health and Human Development (NICHD), Bethesda, MD.

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http://dx.doi.org/10.1097/PCC.0000000000001319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679099PMC
November 2017

Influence of red blood cell-derived microparticles upon vasoregulation.

Blood Transfus 2017 Oct 15;15(6):522-534. Epub 2017 May 15.

Department of Pediatrics, Washington University, St. Louis, MO, United States of America.

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http://www.bloodtransfusion.it/articolosing.aspx?id=000932
Publisher Site
http://dx.doi.org/10.2450/2017.0353-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649961PMC
October 2017

Identifying Risk for Acute Kidney Injury in Infants and Children Following Cardiac Arrest.

Pediatr Crit Care Med 2017 Oct;18(10):e446-e454

1Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 2Division of Nephrology, Hypertension, and Pheresis, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 3Department of Surgery, Washington University School of Medicine, St. Louis, MO. 4Department of Political Science, Washington University School of Medicine, St. Louis, MO. 5Department of Biostatistics, Washington University School of Medicine, St. Louis, MO. 6Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 7Department of Neurology, Washington University School of Medicine, St. Louis, MO. 8Department of Pediatrics, University of Utah, Salt Lake City, UT. 9Division of Critical Care Medicine, Department of Pediatrics, CS Mott Children's Hospital, University of Michigan, Ann Arbor, MI. 10Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO.

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http://dx.doi.org/10.1097/PCC.0000000000001280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628129PMC
October 2017

Transfusion Decision Making in Pediatric Critical Illness.

Pediatr Clin North Am 2017 10;64(5):991-1015

Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, McDonnell Pediatric Research Building, Campus Box 8208, 660 South Euclid Avenue, St Louis, MO 63110-1093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pcl.2017.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664958PMC
October 2017

The American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock: Executive Summary.

Pediatr Crit Care Med 2017 09;18(9):884-890

1No institution affiliation. 2Department of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 3Department of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 4Department of Pediatric Critical Care, Riley Hospital for Children, Indiana University, Bloomington, IN. 5Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 6Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX. 7Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX. 8Pediatric Critical Care Medicine, Covenant Women and Children's Hospital, Texas Tech University, Lubbock, TX. 9Department of Pediatrics, Division of Pediatric Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL. 10Division of Pediatric Critical Care, University of British Columbia, Vancouver, BC, Canada. 11Department of Pediatrics, Division of Pediatric Critical Care Medicine, Medical College of Wisconsin, Milwaukee, WI. 12Department of Pediatrics, Baylor College of Medicine, Houston, TX. 13Department of Pediatrics, Saint Barnabas Medical Center, Livingston, NJ. 14Division of Emergency Medicine and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 15Intensive Care & Bioethics, Great Ormond St Hospital for Sick Children, London, United Kingdom. 16Pediatric Critical Care Medicine, Department of Pediatrics, Stollery Children's Hospital/University of Alberta, Edmonton, AB, Canada. 17Department of Pediatrics, Division of Pediatric Critical Care Medicine, Duke Children's, Durham, NC. 18Departments of Pediatrics and Critical Care, Clinical Epidemiology and Biostatistics, McMaster University, Pediatric Intensive Care Unit, McMaster Children's Hospital, Hamilton, ON, Canada. 19Beth Israel Medical Center, Hartsdale, NY. 20Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI. 21Departments of Pediatrics and Biochemistry, Washington University in Saint Louis School of Medicine, St. Louis, MO. 22Department of Pediatrics, Centre mère-enfant Soleil du CHU de Québec-Université Laval, Québec City, QC, Canada. 23Department of Inpatient Pediatrics, Kaiser Santa Clara Medical Center, Santa Clara, CA. 24Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine and The Children's Hospital of Philadelphia, Philadelphia, PA. 25Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Mott C.S. Children's Hospital, Ann Arbor, MI. 26Division of Critical Care, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA. 27Department of Pediatrics-Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD. 28Division of Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, NY. 29Department of Pediatrics, Division of Critical Care Medicine, Nationwide Children's Hospital, Columbus, OH. 30Department of Critical Care Medicine, Children's Mercy Hospital, Kansas City, MO. 31Department of Pediatrics, Texas Tech University Health Sciences Center, El Paso, TX. 32Division of Pediatric Critical Care, University of Florida, Jacksonville, FL 33Bon Secours St. Mary's Hospital, Glen Allen, VA. 34Department of Pediatrics/Division of Pediatric Critical Care, University of Rochester School of Medicine and Dentistry, Rochester, NY. 35Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. 36Department of Pediatrics, Division of Critical Care, Stanford University School of Medicine, Palo Alto, CA. 37Pediatric Critical Care Medicine, The Children's Hospital at Montefiore, The Pediatric Hospital for Albert Einstein College of Medicine, Bronx, NY. 38Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada. 39Department of Pediatrics, Naval Medical Center San Diego and University of California San Diego School of Medicine, San Diego, CA. 40Department of Pediatrics and Pediatric Critical Care Medicine, The Valley Hospital, Ridgewood, NJ. 41Cardiothoracic ICU, National University Hospital, Singapore. 42Paediatric ICU, The Royal Children's Hospital, Parkville, VIC, Australia. 43Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia. 44Children's Hospital of Pittsburgh, Pittsburgh, PA. 45Department of Pediatrics, Medical College of Georgia at Augusta University, Augusta, GA. 46Department of Pediatrics, Division of Critical Care Medicine, University of Michigan, Ann Arbor, MI. 47Department of Pharmacy Practice, Loma Linda University School of Pharmacy, Loma Linda, CA. 48Division of Emergency Medicine, Ann and Robert Lurie Children's Hospital of Chicago, Feinberg School of Medicine at Northwestern University, Chicago, IL. 49UCL Great Ormond Street Institute of Child Health and Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children, NHS Trust, London, United Kingdom. 50Pediatric Intensive Care and Emergency Services, Apollo Children's Hospital, Chennai, India. 51Department of Pediatrics, Division of Pediatric Critical Care, Duke University School of Nursing and School of Medicine, Durham, NC. 52Pediatrics School of Medicine, Austral University, Pcia de Buenos Aires, Argentina. 53Departments of Pediatrics and Emergency Medicine, University of Colorado School of Medicine, Aurora, CO. 54Critical Care and Transport, Nemours Children's Hospital, Orlando, FL. 55Department of Pediatrics, Critical Care Medicine, Albert Einstein College of Medicine, Bronx, NY. 56Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 57Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Washington School of Medicine, Seattle, WA. 58Departments of Pediatrics & Anesthesiology, Sinai Hospital/NAPA, Baltimore, MD. 59Department of Pediatrics, University of Maryland Medical School, Baltimore, MD.

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http://dx.doi.org/10.1097/PCC.0000000000001259DOI Listing
September 2017

Controlling Phlebotomy Volume Diminishes PICU Transfusion: Implementation Processes and Impact.

Pediatrics 2017 Aug 13;140(2). Epub 2017 Jul 13.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, St Louis Children's Hospital, Washington University School of Medicine in St Louis, St Louis, Missouri.

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http://dx.doi.org/10.1542/peds.2016-2480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527666PMC
August 2017

The authors reply.

Pediatr Crit Care Med 2017 07;18(7):731-732

Division of Critical Care Medicine, Department of Pediatrics, University of Arizona, Tucson, AZ; Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO.

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http://dx.doi.org/10.1097/PCC.0000000000001214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650071PMC
July 2017

American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock.

Crit Care Med 2017 06;45(6):1061-1093

1No institution affiliation. 2Department of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA. 3Department of Pediatric Critical Care, Riley Hospital for Children, Indiana University, IN. 4Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 5Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX. 6Pediatric Critical Care Medicine, Covenant Women and Children's Hospital, Texas Tech University, Lubbock, TX. 7Division of Pediatric Critical Care Medicine, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL. 8Division of Pediatric Critical Care, University of British Columbia, Vancouver, BC, Canada. 9Division of Pediatric Critical Care Medicine, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI. 10Department of Pediatrics, Baylor College of Medicine, Houston, TX. 11Department of Pediatrics, Saint Barnabas Medical Center, Livingston, NJ. 12Division of Emergency Medicine and Center for Pediatric Clinical Effectiveness, University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA. 13Intensive Care & Bioethics, Great Ormond St Hospital for Sick Children, London, United Kingdom. 14Pediatric Critical Care Medicine, Department of Pediatrics, Stollery Children's Hospital/University of Alberta, Edmonton, AB, Canada. 15Division of Pediatric Critical Care Medicine, Department of Pediatrics, Duke Children's, Durham, NC. 16Departments of Pediatrics and Critical Care, Clinical Epidemiology and Biostatistics, McMaster University, Pediatric Intensive Care Unit, McMaster Children's Hospital, Hamilton, ON, Canada. 17Beth Israel Medical Center, Hartsdale, NY. 18Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI. 19Departments of Pediatrics and Biochemistry, Washington University in Saint Louis School of Medicine, Saint Louis, MO. 20Department of Pediatrics, Centre mère-enfant Soleil du CHU de Québec-Université Laval, Québec City, QC, Canada. 21Department of Inpatient Pediatrics, Kaiser Santa Clara Medical Center, Santa Clara, CA. 22Department of Anesthesiology and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA. 23Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Mott C.S. Children's Hospital, Ann Arbor, MI. 24Division of Critical Care, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA. 25Department of Pediatrics-Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD. 26Division of Pediatric Critical Care Medicine, Weill Cornell Medical College, New York, NY. 27Division of Critical Care Medicine, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH. 28Department of Critical Care Medicine, Children's Mercy Hospital, Kansas City, MO. 29Department of Pediatrics, Texas Tech University Health Sciences Center, El Paso, TX. 30Division of Pediatric Critical Care, University of Florida, Jacksonville, FL. 31Bon Secours St. Mary's Hospital, Glen Allen, VA. 32Division of Pediatric Critical Care, Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, NY. 33Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. 34Division of Critical Care, Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA. 35Pediatric Critical Care Medicine, The Children's Hospital at Montefiore, The Pediatric Hospital for Albert Einstein College of Medicine, Bronx, NY. 36Department of Pediatrics, University of British Columbia, UBC & BC Children's Hospital Professor in Critical Care-Global Child Health, Vancouver, BC, Canada. 37Department of Pediatrics, Naval Medical Center San Diego and University of California San Diego School of Medicine, San Diego, CA. 38Department of Pediatrics and Pediatric Critical Care Medicine, The Valley Hospital, Ridgewood, NJ. 39Cardiothoracic ICU, National University Hospital, Singapore. 40Paediatric ICU, The Royal Children's Hospital, Melbourne, Australia. 41Department of Paediatrics, University of Melbourne, Melbourne, Australia. 42Children's Hospital of Pittsburgh, Pittsburgh, PA. 43Department of Pediatrics, Medical College of Georgia at Augusta University, Augusta, GA. 44Division of Critical Care Medicine, Department of Pediatrics, University of Michigan, Ann Arbor, MI. 45Department of Pharmacy Practice, Loma Linda University School of Pharmacy, Loma Linda, CA. 46Division of Emergency Medicine, Ann and Robert Lurie Children's Hospital of Chicago, Feinberg School of Medicine at Northwestern University, Chicago, IL. 47UCL Great Ormond Street Institute of Child Health and Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children, NHS Trust, London, United Kingdom. 48Pediatric Intensive Care and Emergency Services, Apollo Children's Hospital, Chennai, India. 49Division of Pediatric Critical Care, Department of Pediatrics, Duke University School of Nursing and School of Medicine, Durham, NC. 50Pediatrics School of Medicine, Austral University, Pcia de Buenos Aires, Argentina. 51Departments of Pediatrics and Emergency Medicine, University of Colorado School of Medicine, Aurora, CO. 52Critical Care and Transport, Nemours Children's Hospital, Orlando, FL. 53Department of Pediatrics, Critical Care Medicine, Albert Einstein College of Medicine, Bronx, NY. 54Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA. 55Departments of Pediatrics & Anesthesiology, Sinai Hospital/NAPA, Baltimore, MD. 56Department of Pediatrics, University of Maryland Medical School, Baltimore, MD.

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http://dx.doi.org/10.1097/CCM.0000000000002425DOI Listing
June 2017

Specific Etiologies Associated With the Multiple Organ Dysfunction Syndrome in Children: Part 2.

Pediatr Crit Care Med 2017 Mar;18(3_suppl Suppl 1):S58-S66

1Division of Pediatric Surgery, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA. 2Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH. 3Department of Surgery, University of North Carolina, North Carolina Jaycee Burn Center, Chapel Hill, NC. 4Department of Pediatric Surgery, UT-Health, Children's Memorial Hermann Hospital, Houston, TX. 5Departments of Pediatrics and Biochemistry, Washington University in Saint Louis, Saint Louis, MO. 6Pediatric Trauma and Critical Illness Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD.

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http://dx.doi.org/10.1097/PCC.0000000000001051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333166PMC
March 2017

Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies.

Pediatr Crit Care Med 2017 Mar;18(3_suppl Suppl 1):S67-S82

1Departments of Pediatrics (Critical Care Medicine) and Biochemistry, Washington University in St. Louis, St. Louis, MO. 2Department of Pediatrics (Critical Care Medicine), University of Washington, Seattle, WA. 3Department of Pediatrics (Critical Care Medicine), Harvard University, Boston, MA. 4Department of Pediatrics (Critical Care Medicine), Michigan State University, Grand Rapids, MI. 5Departments of Pediatrics (Critical Care Medicine) and Microbiology, University of Chicago, Chicago, IL. 6Department of Pediatrics (Critical Care Medicine), Emory University, Atlanta, GA. 7Obstetric and Pediatric Pharmacology and Therapeutics Branch, NICHD, Bethesda, MD. 8Department of Pediatrics (Critical Care Medicine), University of Arizona, Phoenix, AZ.

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http://dx.doi.org/10.1097/PCC.0000000000001053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333132PMC
March 2017

RBC Distribution Width: Biomarker for Red Cell Dysfunction and Critical Illness Outcome?

Pediatr Crit Care Med 2017 02;18(2):134-142

1Department of Pediatrics, Washington University in St. Louis, St. Louis, MO. 2Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO. 3Department of Biostatistics, Washington University in St. Louis, St. Louis, MO. 4Department of Biochemistry & Molecular Biophysics, Washington University in St. Louis, St. Louis, MO. 5Department of Pediatrics, University of Utah, Salt Lake City, UT.

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http://dx.doi.org/10.1097/PCC.0000000000001017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291765PMC
February 2017

Modulating Vascular Hemodynamics With an Alpha Globin Mimetic Peptide (HbαX).

Hypertension 2016 12 31;68(6):1494-1503. Epub 2016 Oct 31.

From the Department of Molecular Physiology and Biological Physics (T.C.S.K., C.M., M.C., M.P., M.Y., B.E.I.), Robert M. Berne Cardiovascular Research Center (T.C.S.K., J.T.B., G.B.B.-F., C.M., L.J.D., X.S., A.K.B., M.E.G., B.E.I.), Department of Pharmacology (L.J.D.), Division of Nephrology, Department of Medicine (S.C., T.H.L.), and Division of Endocrinology, Department of Medicine (E.B.), University of Virginia School of Medicine, Charlottesville; Department of Physiological Sciences, Federal University of Espirito Santa, Brazil (G.B.B.-F., A.S.P.); Departments of Pediatrics and Biochemistry, Washington University in Saint Louis, MO (S.R., A.D.); Department of Biomedical Engineering (B.N., S.M.P., S.H.) and Department of Chemistry (J.N.M., L.C.), University of Virginia, Charlottesville; and College of Pharmacy, Dalian Medical University, Dalian, China (X.S.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159279PMC
December 2016

Eyes Wide Shut: Improving Physiologic Monitoring During Mechanical Ventilation.

Authors:
Allan Doctor

Pediatr Crit Care Med 2016 12;17(12):1180-1181

Division of Pediatric Critical Care Medicine St. Louis Children's Hospital Washington University School of Medicine St. Louis, MO.

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http://dx.doi.org/10.1097/PCC.0000000000000962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5141610PMC
December 2016

Inherent Risk Factors for Nosocomial Infection in the Long Stay Critically Ill Child Without Known Baseline Immunocompromise: A Post Hoc Analysis of the CRISIS Trial.

Pediatr Infect Dis J 2016 Nov;35(11):1182-1186

From the *Department of Critical Care Medicine and Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania; †Department of Pediatrics, University of Utah, Salt Lake City, Utah; ‡Department of Pediatrics, George Washington University, Washington, DC; §Department of Pediatrics, Wayne State University, Detroit, Michigan; ¶Department of Pediatrics, University of Arkansas, Fayetteville, Arkansas; ‖Department of Pediatrics, University of Washington, Washington, DC; **Department of Pediatrics, University of Southern California, Los Angeles, CA; ††Department of Pediatrics, University of California at Los Angeles, Los Angeles, CA; ‡‡Department of Pediatrics, University of Virginia, Charlottesville, Virginia; §§Eunice Kennedy Shriver National Institutes of Child Health and Development, Rockville, Maryland; ¶¶Department of Pediatrics, University of Pennsylvania, Philadelphia, Pennsylvania; ‖‖Department of Pediatrics, University of Michigan, Ann Arbor, Michigan; ***Department of Pediatrics, University of Arizona, Tucson, Arizona; and †††Department of Pediatrics, Washington University at St. Louis, St. Louis, Missouri.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089838PMC
http://dx.doi.org/10.1097/INF.0000000000001286DOI Listing
November 2016

Incidence and Outcomes of Cardiopulmonary Resuscitation in PICUs.

Crit Care Med 2016 Apr;44(4):798-808

1Department of Anesthesiology and Critical Care, the Children's Hospital of Philadelphia and University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT. 3Department of Pediatrics, University of Michigan, Ann Arbor, MI. 4Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 5Department of Pediatrics, University of California at Los Angeles, Los Angeles, CA. 6Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 7Department of Pediatrics, Children's National Medical Center, Washington DC. 8Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 9Department of Child Health, Phoenix Children's Hospital and University of Arizona College of Medicine-Phoenix, Phoenix, AZ. 10Departments of Pediatrics and Biochemistry, Washington University School of Medicine, St. Louis, MO. 11Branch of Trauma and Critical Illness of the Eunice Kennedy Shriver National Institutes of Child Health and Human Development, the National Institutes of Health, Bethesda, MD. 12Department of Pediatrics, Children's National Medical Center, George Washington University School of Medicine, Washington DC.

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http://dx.doi.org/10.1097/CCM.0000000000001484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809365PMC
April 2016

Fentanyl and Midazolam Are Ineffective in Reducing Episodic Intracranial Hypertension in Severe Pediatric Traumatic Brain Injury.

Crit Care Med 2016 Apr;44(4):809-18

1Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 2Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO. 3Division of Biostatistics, Washington University School of Medicine, St. Louis, MO. 4Department of Neurosurgery, Nationwide Children's Hospital, Ohio State University College of Medicine, Columbus, OH.

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April 2016

Recommendations for utilization of the paracorporeal lung assist device in neonates and young children with pulmonary hypertension.

Pediatr Transplant 2016 Mar 21;20(2):256-70. Epub 2016 Feb 21.

Department of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO, USA.

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March 2016

End-of-Life Practices Among Tertiary Care PICUs in the United States: A Multicenter Study.

Pediatr Crit Care Med 2015 Sep;16(7):e231-8

1Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 2Department of Anesthesia and Critical Care Medicine, Valley Children's Hospital, Madera, CA. 3Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 4Department of Critical Care Medicine, Phoenix Children's Hospital, Phoenix, AZ. 5Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 6Department of Pediatrics, Mattel Children's Hospital at University of California at Los Angeles, Los Angeles, CA. 7Department of Pediatrics, Children's National Medical Center, Washington, DC. 8Department of Pediatrics, University of Michigan, C. S. Mott Children's Hospital, Ann Arbor, MI. 9Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 10Department of Pediatrics, University of Utah School of Medicine, University of Utah, Salt Lake City, UT. 11Eunice Kennedy Shriver National Institute of Child Health and Human Development, Rockville, MD. 12Department of Pediatrics, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO.

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September 2015

Simultaneous Prediction of New Morbidity, Mortality, and Survival Without New Morbidity From Pediatric Intensive Care: A New Paradigm for Outcomes Assessment.

Crit Care Med 2015 Aug;43(8):1699-709

1Department of Pediatrics, Children's National Medical Center and the George Washington University School of Medicine and Health Sciences, Washington, DC. 2Department of Child Health, Phoenix Children's Hospital and the University of Arizona School of Medicine, Phoenix, AZ. 3Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT. 4Department of Pediatrics, Children's National Medical Center, Washington, DC. 5Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 6Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 7Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 8Department of Pediatrics, Children's National Medical Center, Washington, DC. 9Department of Pediatrics, University of Michigan, Ann Arbor, MI. 10Department of Child Health, Phoenix Children's Hospital and University of Arizona College of Medicine-Phoenix, Phoenix, AZ. 11Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 12Department of Pediatrics, University of California at Los Angeles, Los Angeles, CA. 13Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 14Department of Biochemistry, Washington University School of Medicine, St. Louis, MO. 15Pediatric Trauma and Critical Illness Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Institutes of Health, Bethesda, MD.

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August 2015

Red cell physiology and signaling relevant to the critical care setting.

Curr Opin Pediatr 2015 Jun;27(3):267-76

aDepartment of Pediatrics, Division of Critical Care Medicine bDepartment of Biochemistry and Molecular Biophysics, School of Medicine, Washington University in Saint Louis, St. Louis, Missouri, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617548PMC
June 2015

Association of bleeding and thrombosis with outcome in extracorporeal life support.

Pediatr Crit Care Med 2015 Feb;16(2):167-74

1Department of Child Health, Critical Care Medicine, Phoenix Children's Hospital and University of Arizona College of Medicine-Phoenix, Phoenix, AZ. 2Critical Care Medicine, Phoenix Children's Hospital, Phoenix, AZ. 3Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT. 4Department of Pediatrics, University of Michigan, Ann Arbor, MI. 5Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 6Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 7Department of Pediatrics, Children's National Medical Center, Washington, DC. 8Department of Critical Care and Anesthesia, Children's Hospital of Pittsburgh, Pittsburgh, PA. 9Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 10Department of Pediatrics, University of California at Los Angeles, Los Angeles, CA. 11Departments of Pediatrics and Biochemistry, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO. 12The Extracorporeal Life Support Organization, Ann Arbor, MI. 13Pediatric Trauma and Critical Illness Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, The National Institutes of Health, Bethesda, MD.

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February 2015

Pediatric intensive care outcomes: development of new morbidities during pediatric critical care.

Pediatr Crit Care Med 2014 Nov;15(9):821-7

1Department of Child Health, Phoenix Children's Hospital and University of Arizona College of Medicine-Phoenix, Phoenix, AZ. 2Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT. 3Department of Pediatrics, Children's National Medical Center, Washington, DC. 4Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 5Department of Anesthesiology and Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA. 6Department of Pediatrics, University of Michigan, Ann Arbor, MI. 7Department of Critical Care Medicine, Children's Hospital of Pittsburgh, Pittsburgh, PA. 8Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA. 9Department of Pediatrics, University of California at Los Angeles, Los Angeles, CA. 10Departments of Pediatrics and Biochemistry, Washington University School of Medicine, St. Louis, MO. 11Pediatric Trauma and Critical Illness Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, the National Institutes of Health, Bethesda, MD.

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November 2014

How to guide transfusion decision-making? That is the question.

Authors:
Allan Doctor

Pediatr Crit Care Med 2014 Nov;15(9):895-6

Division of Pediatric Critical Care Medicine, Washington University in Saint Louis, Saint Louis, MO.

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November 2014

Citrate anticoagulation during continuous renal replacement therapy in pediatric critical care.

Pediatr Crit Care Med 2014 Jun;15(5):471-85

1Division of Nephrology, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 2Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 3St. Louis Children's Hospital, St. Louis, MO.

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June 2014

Role of transfused red blood cells for shock and coagulopathy within remote damage control resuscitation.

Shock 2014 May;41 Suppl 1:30-4

*Division of Critical Care, Department of Pediatrics, Washington University in St Louis, St Louis, Missouri and †Department of Biochemistry, Washington University in St Louis, St Louis, Missouri.

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May 2014

Feasibility and perceived benefits of a framework for physician-parent follow-up meetings after a child's death in the PICU.

Crit Care Med 2014 Jan;42(1):148-57

1Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 2Department of Oncology, Karmanos Cancer Institute, Detroit, MI. 3Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA. 4Department of Pediatrics, Children's National Medical Center, Washington, DC. 5Department of Anesthesiology and Critical Care, Children's Hospital Los Angeles, Los Angeles, CA. 6Department of Pediatrics and Communicable Diseases, C.S. Mott Children's Hospital, Ann Arbor, MI. 7Department of Child Health, Mattel Children's Hospital at University of California Los Angeles, Los Angeles, CA. 8Department of Pediatrics, Phoenix Children's Hospital, Phoenix, AZ. 9Department of Pediatrics, University of Utah, Salt Lake City, UT. 10Departments of Pediatrics and Biochemistry, St. Louis Children's Hospital, St. Louis, MO. 11National Institute of Child Health and Human Development, Bethesda, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867593PMC
January 2014

Ratio of PICU versus ward cardiopulmonary resuscitation events is increasing.

Crit Care Med 2013 Oct;41(10):2292-7

1Division of Critical Care Medicine, Department of Anesthesiology and Critical Care, The Children's Hospital of Philadelphia and The University of Pennsylvania Perelman School of Medicine, Philadelphia, PA. 2Department of Pediatrics, University of Utah, Salt Lake City, UT. 3Division of Critical Care Medicine, Department of Pediatrics, National Institute of Child Health and Human Development, Bethesda, MD. 4Division of Critical Care Medicine, Department of Pediatrics, University of California at Los Angeles, Los Angeles, CA. 5Division of Critical Care Medicine, Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI. 6Division of Critical Care Medicine, Department of Anesthesiology and Critical Care, Children's Hospital Los Angeles, Los Angeles, CA. 7Division of Critical Care Medicine, Department of Pediatrics, University of Michigan and Mott Children's Hospital, Ann Arbor, MI. 8Division of Critical Care Medicine, Department of Pediatrics, Phoenix Children's Hospital, Phoenix, AZ. 9Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO. 10Division of Critical Care Medicine, Department of Pediatrics, Children's National Medical Center, Washington, DC. 11Department of Critical Care Medicine, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

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October 2013

Analysis of S-nitrosothiols via copper cysteine (2C) and copper cysteine-carbon monoxide (3C) methods.

Methods 2013 Aug 29;62(2):123-9. Epub 2012 Oct 29.

Department of Pediatrics, Division of Critical Care Medicine, Washington University School of Medicine, 1 Children’s Place, St. Louis, MO 63110, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584190PMC
August 2013

Sickle hemoglobin disturbs normal coupling among erythrocyte O2 content, glycolysis, and antioxidant capacity.

Blood 2013 Feb 7;121(9):1651-62. Epub 2013 Jan 7.

Division of Critical Care Medicine, Department of Pediatrics, Washington University School of Medicine, 1 Children's Pl, St Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3587328PMC
February 2013

Effect of implementation of a paediatric neurocritical care programme on outcomes after severe traumatic brain injury: a retrospective cohort study.

Lancet Neurol 2013 Jan 28;12(1):45-52. Epub 2012 Nov 28.

Department of Pediatrics, Division of Critical Care Medicine, Washington University School of Medicine, St Louis, MO 63110, USA.

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January 2013

Effect of processing and storage on red blood cell function in vivo.

Semin Perinatol 2012 Aug;36(4):248-59

Division of Pediatric Critical Care Medicine, Washington University School of Medicine, St Louis Children's Hospital, St Louis, MO 63110, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404625PMC
August 2012

Evolution of surfactant protein-D levels in children with ventilator-associated pneumonia.

Pediatr Pulmonol 2012 Mar 7;47(3):292-9. Epub 2011 Sep 7.

Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

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March 2012

Nitric oxide transport in blood: a third gas in the respiratory cycle.

Compr Physiol 2011 Jan;1(1):541-68

Washington University School of Medicine, Department of Pediatrics, St. Louis, MO, USA.

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January 2011

Direct regulation of striated muscle myosins by nitric oxide and endogenous nitrosothiols.

PLoS One 2010 Jun 18;5(6):e11209. Epub 2010 Jun 18.

Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America.

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June 2010

Fresh goat's milk for infants: myths and realities--a review.

Pediatrics 2010 Apr 15;125(4):e973-7. Epub 2010 Mar 15.

Southern Illinois University School of Medicine, Department of Pediatrics, Division of Pediatric Critical Care, PO Box 19676, Springfield, IL 62794-9676, USA.

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April 2010

Hypoxia limits antioxidant capacity in red blood cells by altering glycolytic pathway dominance.

FASEB J 2009 Sep 5;23(9):3159-70. Epub 2009 May 5.

Department of Pediatrics, Washington University in St. Louis, St. Louis, MO, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735367PMC
September 2009

SNO-hemoglobin and hypoxic vasodilation.

Nat Med 2008 Oct;14(10):1009; author reply 1009-10

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October 2008

Evolution of adverse changes in stored RBCs.

Proc Natl Acad Sci U S A 2007 Oct 11;104(43):17063-8. Epub 2007 Oct 11.

Department of Anesthesiology, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040393PMC
October 2007

S-nitrosothiols signal hypoxia-mimetic vascular pathology.

J Clin Invest 2007 Sep;117(9):2592-601

Department of Pediatrics, University of Virginia School of Medicine, Virginia 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952618PMC
September 2007

S-Nitrosothiol measurements in biological systems.

J Chromatogr B Analyt Technol Biomed Life Sci 2007 May 25;851(1-2):140-51. Epub 2007 Feb 25.

School of Pharmacology and Toxicology, Rutgers University, 160 Frelinghuysen Road Piscataway, NJ 08854, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1949323PMC
May 2007

Functional regulation of T-type calcium channels by s-nitrosothiols in the rat thalamus.

J Neurophysiol 2007 Apr 7;97(4):2712-21. Epub 2007 Feb 7.

Dept. of Anesthesiology, University of Virginia Health System, Mail Box 800710, Charlottesville, VA 22908-0710, USA.

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April 2007

Alveolar macrophage activation is a key initiation signal for acute lung ischemia-reperfusion injury.

Am J Physiol Lung Cell Mol Physiol 2006 Nov 21;291(5):L1018-26. Epub 2006 Jul 21.

Department of Surgery, University of Virginia Health System, P.O. Box 801359, Charlottesville, 22908, USA.

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November 2006

S-nitrosylating agents: a novel class of compounds that increase cystic fibrosis transmembrane conductance regulator expression and maturation in epithelial cells.

Mol Pharmacol 2006 Oct 20;70(4):1435-42. Epub 2006 Jul 20.

Department of Pediatrics, University of Virginia Health System, Pediatric Respiratory Medicine, Box 800386, Charlottesville, VA 22908, USA.

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October 2006

Buffering airway acid decreases exhaled nitric oxide in asthma.

J Allergy Clin Immunol 2006 Oct 1;118(4):817-22. Epub 2006 Sep 1.

Department of Pediatric Respiratory Medicine, The University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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October 2006

S-nitrosothiol signaling in respiratory biology.

Am J Respir Crit Care Med 2006 Jun 9;173(11):1186-93. Epub 2006 Mar 9.

Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662966PMC
June 2006

Effects of nitroglycerin on erythrocyte rheology and oxygen unloading: novel role of S-nitrosohemoglobin in relieving myocardial ischemia.

Circulation 2006 May 22;113(21):2502-8. Epub 2006 May 22.

Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.

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May 2006

Extrapulmonary effects of inhaled nitric oxide: role of reversible S-nitrosylation of erythrocytic hemoglobin.

Proc Am Thorac Soc 2006 Apr;3(2):153-60

Durham Veterans Affairs and Duke University Medical Centers, Durham, North Carolina 27710, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2658680PMC
April 2006

S-nitrosothiol formation.

Methods Enzymol 2005 ;396:95-105

Department of Pediatrics, Critical Care Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.

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January 2006

Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients.

Proc Natl Acad Sci U S A 2005 Apr 11;102(16):5709-14. Epub 2005 Apr 11.

Department of Pediatric Critical Care, University of Virginia, Charlottesville, VA 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC556285PMC
April 2005

Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1.

Biochem J 2004 May;380(Pt 1):67-74

Division of Pulmonary Medicine, Department of Pediatrics, University of Virginia School of Medicine, P.O. Box 800356, Charlottesville, VA 22908, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224145PMC
May 2004

Tumor necrosis factor-alpha from resident lung cells is a key initiating factor in pulmonary ischemia-reperfusion injury.

J Thorac Cardiovasc Surg 2004 Feb;127(2):541-7

Division of Thoracic and Cardiovascular Surgery, University of Virginia Health System, Charlottesville 22908, USA.

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February 2004

Extended high-frequency partial liquid ventilation in lung injury: gas exchange, injury quantification, and vapor loss.

J Appl Physiol (1985) 2003 Sep 16;95(3):1248-58. Epub 2003 May 16.

Division of Pediatric Critical Care, University of Virginia, Charlottesville, VA 22908-0386, USA.

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http://dx.doi.org/10.1152/japplphysiol.00598.2002DOI Listing
September 2003

S-nitrosylation signaling in cell biology.

Mol Interv 2003 Aug;3(5):253-63

Department of Pediatrics, Division of Respiratory Medicine, University of Virginia School of Medicine, Charlottesville, Virginia 22908 USA.

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August 2003

Inhaled prostacyclin for the treatment of pulmonary hypertension after cardiac surgery.

Crit Care Med 2002 Dec;30(12):2762-4

Department of Anesthesiology, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA.

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December 2002