Alison Condliffe

Alison Condliffe

UNVERIFIED PROFILE

Are you Alison Condliffe?   Register this Author

Register author
Alison Condliffe

Alison Condliffe

Publications by authors named "Alison Condliffe"

Are you Alison Condliffe?   Register this Author

47Publications

1209Reads

24Profile Views

Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry.

Front Immunol 2018 16;9:543. Epub 2018 Mar 16.

Center for Chronic Immunodeficiency, Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://journal.frontiersin.org/article/10.3389/fimmu.2018.00
Publisher Site
http://dx.doi.org/10.3389/fimmu.2018.00543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863269PMC
May 2019

Respiratory Manifestations of the Activated Phosphoinositide 3-Kinase Delta Syndrome.

Front Immunol 2018 5;9:338. Epub 2018 Mar 5.

Department of Medicine, University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2018.00338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844940PMC
March 2019

Reply.

J Allergy Clin Immunol 2019 Mar 11;143(3):1265-1266. Epub 2019 Jan 11.

Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00916749183173
Publisher Site
http://dx.doi.org/10.1016/j.jaci.2018.11.026DOI Listing
March 2019

The clinical consequences of neutrophil priming.

Curr Opin Hematol 2019 Jan;26(1):22-27

Department of Infection, Immunity and Cardiovascular Diseases, University of Sheffield.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MOH.0000000000000471DOI Listing
January 2019

Priming and de-priming of neutrophil responses in vitro and in vivo.

Eur J Clin Invest 2018 Nov 5;48 Suppl 2:e12967. Epub 2018 Jul 5.

Department of Infection, Immunity and Cardiovascular Diseases, University of Sheffield, Sheffield, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/eci.12967DOI Listing
November 2018

Phosphoinositide 3-kinase δ (PI3Kδ) in respiratory disease.

Biochem Soc Trans 2018 04 9;46(2):361-369. Epub 2018 Mar 9.

Department of Infection, Immunity and Cardiovascular Disease, School of Medicine, Dentistry and Health, University of Sheffield, Sheffield, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BST20170467DOI Listing
April 2018

Hypoxic regulation of neutrophil function and consequences for Staphylococcus aureus infection.

Microbes Infect 2017 Mar 24;19(3):166-176. Epub 2016 Oct 24.

Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.micinf.2016.10.005DOI Listing
March 2017

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

J Allergy Clin Immunol 2017 02 16;139(2):597-606.e4. Epub 2016 Jul 16.

Department of Paediatric Immunology, Newcastle upon Tyne hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2016.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292996PMC
February 2017

Hypoxia upregulates neutrophil degranulation and potential for tissue injury.

Thorax 2016 11 31;71(11):1030-1038. Epub 2016 Aug 31.

Department of Medicine, University of Cambridge, Cambridge, UK Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2015-207604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099189PMC
November 2016

PI3Kδ and primary immunodeficiencies.

Nat Rev Immunol 2016 11 12;16(11):702-714. Epub 2016 Sep 12.

Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB22 3AT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nri.2016.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291318PMC
November 2016

Measurement of eosinophil kinetics in healthy volunteers.

Methods Mol Biol 2014 ;1178:165-76

Department of Medicine, Addenbrooke's and Papworth Hospitals, University of Cambridge School of Clinical Medicine, Cambridge, CB2 0QQ, UK,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-1016-8_15DOI Listing
February 2015

Biomarkers of eosinophilic inflammation in asthma.

Expert Rev Respir Med 2014 Apr 27;8(2):143-50. Epub 2014 Jan 27.

Department of Medicine, Division of Respiratory Medicine, University of Cambridge, School of Clinical Medicine, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/17476348.2014.880052DOI Listing
April 2014

Use of technetium-99m-labeled eosinophils to detect active eosinophilic inflammation in humans.

Am J Respir Crit Care Med 2013 Oct;188(7):880-2

1 University of Cambridge School of Clinical Medicine Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.201303-0535LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3826271PMC
October 2013

The neutrophil in chronic obstructive pulmonary disease.

Am J Respir Cell Mol Biol 2013 May;48(5):531-9

University of Cambridge, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1165/rcmb.2012-0492TRDOI Listing
May 2013

Coexistence of bronchiectasis and rheumatoid arthritis: revisited.

Respir Care 2013 Apr;58(4):694-701

Respiratory Medicine Department, Prince Philip Hospital, Llanelli, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4187/respcare.01857DOI Listing
April 2013

Neutrophil kinetics in health and disease.

Trends Immunol 2010 Aug;31(8):318-24

Department of Medicine, University of Cambridge School of Medicine, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.it.2010.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930213PMC
August 2010

Advances in neutrophil biology: clinical implications.

Chest 2008 Sep;134(3):606-612

Respiratory Medicine Division, Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Papworth Hospitals, Cambridge, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.08-0422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827863PMC
September 2008

RhoG regulates the neutrophil NADPH oxidase.

J Immunol 2006 May;176(9):5314-20

Inositide Laboratory, Babraham Institute, Babraham Research Campus, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.176.9.5314DOI Listing
May 2006

P-Rex1 regulates neutrophil function.

Curr Biol 2005 Oct;15(20):1867-73

Inositide Laboratory, The Babraham Institute, Babraham Research Campus, Cambridge CB2 4AT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2005.09.050DOI Listing
October 2005

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity.

J Exp Med 2005 Jan;201(1):105-15

Division of Respiratory Medicine, Department of Medicine, School of Clinical Medicine, University of Cambridge, Addenbrooke's and Papworth Hospitals, Cambridge, CB2 2QQ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20040624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212759PMC
January 2005

Effect of priming on activation and localization of phospholipase D-1 in human neutrophils.

Eur J Biochem 2004 Jul;271(13):2755-64

Respiratory Medicine Division, Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Papworth Hospitals, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1432-1033.2004.04204.xDOI Listing
July 2004

Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents.

J Immunol 2002 Sep;169(6):3336-44

Respiratory Medicine Division, Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Papworth Hospitals, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.169.6.3336DOI Listing
September 2002