Aline Bozec

Aline Bozec

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Aline Bozec

Aline Bozec

Publications by authors named "Aline Bozec"

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Osteoprotective action of low-salt diet requires myeloid cell-derived NFAT5.

JCI Insight 2019 Dec 5;4(23). Epub 2019 Dec 5.

Institute of Clinical Microbiology and Hygiene, University Hospital Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1172/jci.insight.127868DOI Listing
December 2019

Changes in mechanical loading affect arthritis-induced bone loss in mice.

Bone 2019 Nov 9;131:115149. Epub 2019 Nov 9.

Friedrich-Alexander-University Erlangen-Nuremberg (FAU), Department of Internal Medicine 3 -Rheumatology & Immunology, University Hospital Erlangen, Erlangen, Germany; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.115149DOI Listing
November 2019

Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss.

J Bone Miner Res 2019 Jul 19;34(7):1352-1365. Epub 2019 Mar 19.

Department of Medicine 3, Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1002/jbmr.3705DOI Listing
July 2019

How Autoantibodies Regulate Osteoclast Induced Bone Loss in Rheumatoid Arthritis.

Front Immunol 2019 3;10:1483. Epub 2019 Jul 3.

Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.01483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619397PMC
July 2019

In Vivo Models of Rheumatoid Arthritis.

Methods Mol Biol 2019 ;1914:269-280

Department of Medicine 3, Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Germany.

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http://link.springer.com/10.1007/978-1-4939-8997-3_14
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http://dx.doi.org/10.1007/978-1-4939-8997-3_14DOI Listing
June 2019

Anti-inflammatory and immune-regulatory cytokines in rheumatoid arthritis.

Nat Rev Rheumatol 2019 Jan;15(1):9-17

Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg and Universitatsklinikum Erlangen, Erlangen, Germany.

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http://www.nature.com/articles/s41584-018-0109-2
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http://dx.doi.org/10.1038/s41584-018-0109-2DOI Listing
January 2019

Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin.

Mol Cell Biol 2018 11 29;38(22). Epub 2018 Oct 29.

Friedrich-Alexander University Erlangen-Nürnberg, Department of Internal Medicine 3 Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany

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http://mcb.asm.org/lookup/doi/10.1128/MCB.00022-18
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http://dx.doi.org/10.1128/MCB.00022-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206458PMC
November 2018

Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice.

Cell Rep 2018 07;24(1):169-180

Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.005DOI Listing
July 2018

New insights into the key role of HIF-1α in IL-10-producing B cells.

Cell Stress 2018 Mar 22;2(4):94-95. Epub 2018 Mar 22.

Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, 91054, Germany.

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http://dx.doi.org/10.15698/cst2018.04.133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551746PMC
March 2018

Abatacept blocks anti-citrullinated protein antibody and rheumatoid factor mediated cytokine production in human macrophages in IDO-dependent manner.

Arthritis Res Ther 2018 02 7;20(1):24. Epub 2018 Feb 7.

Department of Internal Medicine 3 and Institute for Clinical Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum, Ulmenweg 18, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13075-018-1527-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803926PMC
February 2018

The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis.

Ann Rheum Dis 2018 Jan 25;77(1):150-158. Epub 2017 Oct 25.

Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and University Hospital Erlangen, Erlangen, Bayern, Germany.

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http://dx.doi.org/10.1136/annrheumdis-2017-211501DOI Listing
January 2018

Hypoxia-inducible factor-1α is a critical transcription factor for IL-10-producing B cells in autoimmune disease.

Nat Commun 2018 01 17;9(1):251. Epub 2018 Jan 17.

Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, 91054, Erlangen, Germany.

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http://www.nature.com/articles/s41467-017-02683-x
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http://dx.doi.org/10.1038/s41467-017-02683-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772476PMC
January 2018

Galectin-3 as a novel regulator of osteoblast-osteoclast interaction and bone homeostasis.

Bone 2017 Dec 16;105:35-41. Epub 2017 Aug 16.

Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.08.013DOI Listing
December 2017

A defined metabolic state in pre B cells governs B-cell development and is counterbalanced by Swiprosin-2/EFhd1.

Cell Death Differ 2017 07 19;24(7):1239-1252. Epub 2017 May 19.

Department of Internal Medicine 3, Division of Molecular Immunology, Nikolaus-Fiebiger-Center, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1038/cdd.2017.52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520169PMC
July 2017

Fra-2 regulates B cell development by enhancing IRF4 and Foxo1 transcription.

J Exp Med 2017 Jul 31;214(7):2059-2071. Epub 2017 May 31.

Department of Internal Medicine 3 - Rheumatology and Immunology, Universitätsklinikum Erlangen, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

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http://dx.doi.org/10.1084/jem.20160514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502419PMC
July 2017

T Regulatory Cells in Bone Remodelling.

Curr Osteoporos Rep 2017 06;15(3):121-125

Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Universitätsklinikum Erlangen, Erlangen, Germany.

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http://dx.doi.org/10.1007/s11914-017-0356-1DOI Listing
June 2017

The AP-1 Transcription Factor c-Jun Promotes Arthritis by Regulating Cyclooxygenase-2 and Arginase-1 Expression in Macrophages.

J Immunol 2017 05 15;198(9):3605-3614. Epub 2017 Mar 15.

Department of Internal Medicine 3-Rheumatology and Immunology, University Hospital Erlangen, Friedrich Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany;

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http://dx.doi.org/10.4049/jimmunol.1601330DOI Listing
May 2017

Latest perspectives on macrophages in bone homeostasis.

Pflugers Arch 2017 04 28;469(3-4):517-525. Epub 2017 Feb 28.

Department of Microbiology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, 91054, Germany.

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http://dx.doi.org/10.1007/s00424-017-1952-8DOI Listing
April 2017

Th2 and eosinophil responses suppress inflammatory arthritis.

Nat Commun 2016 06 7;7:11596. Epub 2016 Jun 7.

Department of Internal Medicine 3, University Hospital Erlangen and Friedrich Alexander University of Erlangen-Nuremberg, Gluckstrasse 6, Erlangen 91054, Germany.

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http://dx.doi.org/10.1038/ncomms11596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899615PMC
June 2016

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis.

J Vis Exp 2016 06 3(112). Epub 2016 Jun 3.

Department of Medicine 3, Rheumatology and Immunology, Universitätsklinikum Erlangen; Nikolaus Fiebiger Center of Molecular Medicine, Universitätsklinikum Erlangen.

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http://dx.doi.org/10.3791/53822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927764PMC
June 2016

Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche.

Cell Metab 2015 Nov 17;22(5):886-94. Epub 2015 Sep 17.

Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen 91054, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.08.020DOI Listing
November 2015

The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells.

J Exp Med 2014 Oct 6;211(11):2199-212. Epub 2014 Oct 6.

Division of Molecular Immunology, Nikolaus Fiebiger Center, Department of Internal Medicine III, Department of Radiation Oncology, Division of Ophthalmology, Department Kopfklinik, University of Erlangen-Nuremberg, D91054 Erlangen, Germany Institute for Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, D20246 Hamburg, Germany

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http://jem.rupress.org/content/211/11/2199.full.pdf
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http://www.jem.org/lookup/doi/10.1084/jem.20130795
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http://dx.doi.org/10.1084/jem.20130795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203943PMC
October 2014

Removing the bone brake.

Cell Metab 2014 Sep;20(3):394-5

Department of Internal Medicine 3 and Institute of Clinical Immunology, University of Erlangen-Nuremberg, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.cmet.2014.08.009DOI Listing
September 2014

The nuclear receptor Nr4a1 mediates anti-inflammatory effects of apoptotic cells.

J Immunol 2014 May 16;192(10):4852-8. Epub 2014 Apr 16.

Department of Internal Medicine 3 and Institute for Clinical Immunology, Erlangen, Erlangen 91054, Germany;

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http://dx.doi.org/10.4049/jimmunol.1303377DOI Listing
May 2014

Osteoblast-specific expression of Fra-2/AP-1 controls adiponectin and osteocalcin expression and affects metabolism.

J Cell Sci 2013 Dec 17;126(Pt 23):5432-40. Epub 2013 Sep 17.

Genes, Development and Disease Group, F-BBVA-CNIO Cancer Cell Biology Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.

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http://dx.doi.org/10.1242/jcs.134510DOI Listing
December 2013

FOSL2 promotes leptin gene expression in human and mouse adipocytes.

J Clin Invest 2012 Mar 13;122(3):1010-21. Epub 2012 Feb 13.

Division of Endocrinology, Diabetes, and Metabolism, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://www.jci.org/articles/view/58431
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http://dx.doi.org/10.1172/JCI58431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322535PMC
March 2012

Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.

J Cell Biol 2010 Sep 13;190(6):1093-106. Epub 2010 Sep 13.

Genes, Development, and Disease Group, BBVA Foundation, Cancer Cell Biology Program, Spanish National Cancer Center, E-28029 Madrid, Spain.

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http://dx.doi.org/10.1083/jcb.201002111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101588PMC
September 2010

Phosphate-dependent regulation of MGP in osteoblasts: role of ERK1/2 and Fra-1.

J Bone Miner Res 2009 Nov;24(11):1856-68

INSERM, U 791, Laboratoire d'Ingénierie des Tissus Ostéo-Articulaires et Dentaires, Groupe Physiopathologie des Tissus Squelettiques et Ingénierie du Cartilage, Nantes, France.

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http://dx.doi.org/10.1359/jbmr.090508DOI Listing
November 2009

Status of the executioner step of apoptosis in human with normal spermatogenesis and azoospermia.

Fertil Steril 2008 Nov 3;90(5):1723-31. Epub 2008 Jan 3.

Faculté de Médecine Lyon Sud, Inserm, U407, Oullins, Université de Lyon, Lyon, Université Lyon1, France.

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http://dx.doi.org/10.1016/j.fertnstert.2007.09.058DOI Listing
November 2008

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia.

Nature 2008 Jul 11;454(7201):221-5. Epub 2008 Jun 11.

Research Institute of Molecular Pathology (I.M.P.), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1038/nature07019DOI Listing
July 2008

Androgens and postmeiotic germ cells regulate claudin-11 expression in rat Sertoli cells.

Endocrinology 2005 Mar 9;146(3):1532-40. Epub 2004 Dec 9.

Institut National de la Santé et de la Recherche Médicale, Unité 407, Faculté de Médecine Lyon-Sud, BP 12, 69921 Oullins Cedex, France.

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http://dx.doi.org/10.1210/en.2004-0834DOI Listing
March 2005

Activation of caspases-3, -6, and -9 during finasteride treatment of benign prostatic hyperplasia.

J Clin Endocrinol Metab 2005 Jan 26;90(1):17-25. Epub 2004 Oct 26.

Institut National de la Santé et de la Recherche Médicale U 407, Faculté de Médecine Lyon-Sud, BP 12, 69921 Oullins Cedex, France.

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http://dx.doi.org/10.1210/jcem.90.8.9993DOI Listing
January 2005