Publications by authors named "Alicia K Smith"

99Publications

Epigenome-wide association study of diet quality in the Women's Health Initiative and TwinsUK cohort.

Authors:
Whitney L Do Eric A Whitsel Ricardo Costeira Olatz M Masachs Caroline I Le Roy Jordana T Bell Lisa RStaimez Aryeh D Stein Alicia K Smith Steve Horvath Themistocles L Assimes Simin Liu JoAnn E Manson Aladdin H Shadyab Yun Li Lifang Hou Parveen Bhatti Kristina Jordahl K M Venkat Narayan Karen N Conneely

Int J Epidemiol 2020 Dec 23. Epub 2020 Dec 23.

Department of Human Genetics, School of Medicine, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
December 2020

Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR.

Authors:
Alicia K Smith Andrew Ratanatharathorn Adam X Maihofer Robert K Naviaux Allison E Aiello Ananda B Amstadter Allison E Ashley-Koch Dewleen G Baker Jean C Beckham Marco P Boks Evelyn Bromet Michelle Dennis Sandro Galea Melanie E Garrett Elbert Geuze Guia Guffanti Michael A Hauser Seyma Katrinli Varun Kilaru Ronald C Kessler Nathan A Kimbrel Karestan C Koenen Pei-Fen Kuan Kefeng Li Mark W Logue Adriana Lori Benjamin J Luft Mark W Miller Jane C Naviaux Nicole R Nugent Xuejun Qin Kerry J Ressler Victoria B Risbrough Bart P F Rutten Murray B Stein Robert J Ursano Eric Vermetten Christiaan H Vinkers Lin Wang Nagy A Youssef Monica Uddin Caroline M Nievergelt

Nat Commun 2020 11 24;11(1):5965. Epub 2020 Nov 24.

University of California San Diego, Department of Psychiatry, La Jolla, CA, USA.

View Article and Find Full Text PDF
November 2020

PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L.

Authors:
Seyma Katrinli Yuanchao Zheng Aarti Gautam Rasha Hammamieh Ruoting Yang Suresh Venkateswaran Varun Kilaru Adriana Lori Rebecca Hinrichs Abigail Powers Charles F Gillespie Aliza P Wingo Vasiliki Michopoulos Tanja Jovanovic Erika J Wolf Regina E McGlinchey William P Milberg Mark W Miller Subra Kugathasan Marti Jett Mark W Logue Kerry J Ressler Alicia K Smith

Brain Behav Immun 2021 Jan 3;91:429-436. Epub 2020 Nov 3.

Emory University, Department of Gynecology and Obstetrics, Atlanta, GA, USA; Emory University School of Medicine, Department of Psychiatry and Behavioral Sciences, Atlanta, GA, USA. Electronic address:

View Article and Find Full Text PDF
January 2021

Maternal exposure to childhood traumatic events, but not multi-domain psychosocial stressors, predict placental corticotrophin releasing hormone across pregnancy.

Authors:
Iris M Steine Kaja Z LeWinn Nadra Lisha Frances Tylavsky Roger Smith Maria Bowman Sheela Sathyanarayana Catherine J Karr Alicia K Smith Michael Kobor Nicole R Bush

Soc Sci Med 2020 Dec 17;266:113461. Epub 2020 Oct 17.

Departments of Psychiatry and Pediatrics, University of California San Francisco, USA.

View Article and Find Full Text PDF
December 2020

Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques.

Authors:
Desirée De Leon Shota Nishitani Hasse Walum Kai M McCormack Mark E Wilson Alicia K Smith Larry J Young Mar M Sanchez

Horm Behav 2020 Nov 14;126:104856. Epub 2020 Oct 14.

Yerkes National Primate Research Center, Emory University, Atlanta, GA, United States of America; Silvio O. Conte Center for Oxytocin and Social Cognition, Emory University, Atlanta, GA, United States of America; Center for Translational Social Neuroscience, Emory University, Atlanta, GA, United States of America; Dept. of Psychiatry & Behavioral Sciences, Emory School of Medicine, Emory University, Atlanta, GA, United States of America. Electronic address:

View Article and Find Full Text PDF
November 2020

Pathways linking adverse environments to emerging adults' substance abuse and depressive symptoms: A prospective analysis of rural African American men.

Authors:
Steven M Kogan Dayoung Bae Junhan Cho Alicia K Smith Shota Nishitani

Dev Psychopathol 2020 Jul 22:1-11. Epub 2020 Jul 22.

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
July 2020

Genome-wide DNA methylation differences and polychlorinated biphenyl (PCB) exposure in a US population.

Authors:
Sarah W Curtis Dawayland O Cobb Varun Kilaru Metrecia L Terrell M Elizabeth Marder Dana Boyd Barr Carmen J Marsit Michele Marcus Karen N Conneely Alicia K Smith

Epigenetics 2020 Jul 22:1-15. Epub 2020 Jul 22.

Departments of Gynecology and Obstetrics & Psychiatry and Behavioral Science, Emory University School of Medicine , Atlanta, GA, USA.

View Article and Find Full Text PDF
July 2020

Maternal prenatal depression and epigenetic age deceleration: testing potentially confounding effects of prenatal stress and SSRI use.

Authors:
Brooke G McKenna Cassandra L Hendrix Patricia A Brennan Alicia K Smith Zachary N Stowe D Jeffrey Newport Anna K Knight

Epigenetics 2020 Jul 24:1-11. Epub 2020 Jul 24.

Department of Gynecology and Obstetrics, Emory University , Atlanta, GA, USA.

View Article and Find Full Text PDF
July 2020

Transcription factor AP2A affects sFLT1 expression and decidualization in decidual stromal cells: Implications to preeclampsia pathology.

Authors:
Charisma N Manley Venkataraman Deepak Nithin Ravikumar Alicia K Smith Anna K Knight Martina L Badell Neil Sidell Augustine Rajakumar

Pregnancy Hypertens 2020 Jul 8;21:152-158. Epub 2020 Jun 8.

Division of Research, Emory University School of Medicine, Atlanta, GA, United States; Department of Gynecology & Obstetrics, Emory University School of Medicine, Atlanta, GA, United States. Electronic address:

View Article and Find Full Text PDF
July 2020

Maternal trauma and fear history predict methylation and gene expression in newborns.

Authors:
Stefanie R Pilkay Terri Combs-Orme Frances Tylavsky Nicole Bush Alicia K Smith

PeerJ 2020 22;8:e8858. Epub 2020 May 22.

Department of Gynecology and Obstetrics, Emory University, Atlanta, GA, United States of America.

View Article and Find Full Text PDF
May 2020

Sex-specific DNA methylation differences in people exposed to polybrominated biphenyl.

Authors:
Sarah W Curtis Sabrina A Gerkowicz Dawayland O Cobb Varun Kilaru Metrecia L Terrell M Elizabeth Marder Dana Boyd Barr Carmen J Marsit Michele Marcus Karen N Conneely Alicia K Smith

Epigenomics 2020 05 4;12(9):757-770. Epub 2020 Jun 4.

Department of Gynecology & Obstetrics, Emory University School of Medicine, 101 Woodruff Circle NE, Ste 4217, Atlanta, GA 30322, USA.

View Article and Find Full Text PDF
May 2020

Epigenome-wide association study and multi-tissue replication of individuals with alcohol use disorder: evidence for abnormal glucocorticoid signaling pathway gene regulation.

Authors:
Falk W Lohoff Arunima Roy Jeesun Jung Martha Longley Daniel B Rosoff Audrey Luo Emma O'Connell Jill L Sorcher Hui Sun Melanie Schwandt Colin A Hodgkinson David Goldman Reza Momenan Andrew M McIntosh Mark J Adams Rosie M Walker Kathryn L Evans David Porteous Alicia K Smith Jisoo Lee Christine Muench Katrin Charlet Toni-Kim Clarke Zachary A Kaminsky

Mol Psychiatry 2020 May 12. Epub 2020 May 12.

Royal's Institute of Mental Health Research, University of Ottawa, Ottawa, Canada.

View Article and Find Full Text PDF
May 2020

Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity.

Authors:
Seyma Katrinli Jennifer Stevens Agaz H Wani Adriana Lori Varun Kilaru Sanne J H van Rooij Rebecca Hinrichs Abigail Powers Charles F Gillespie Vasiliki Michopoulos Aarti Gautam Marti Jett Rasha Hammamieh Ruoting Yang Derek Wildman Annie Qu Karestan Koenen Allison E Aiello Tanja Jovanovic Monica Uddin Kerry J Ressler Alicia K Smith

Neuropsychopharmacology 2020 09 7;45(10):1609-1616. Epub 2020 May 7.

Department of Gynecology and Obstetrics, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
September 2020

Glucocorticoid receptor sensitivity in early pregnancy in an African American cohort.

Authors:
Lasha S Clarke Elizabeth J Corwin Anne L Dunlop Allison Hankus Joshua M Bradner Sudeshna Paul Yunshen Jiao Alicia K Smith Nikolay Patrushev Jennifer G Mulle Timothy D Read Carol J R Hogue Bradley D Pearce

Am J Reprod Immunol 2020 07 23;84(1):e13252. Epub 2020 May 23.

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
July 2020

An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci.

Authors:
Mark W Logue Mark W Miller Erika J Wolf Bertrand Russ Huber Filomene G Morrison Zhenwei Zhou Yuanchao Zheng Alicia K Smith Nikolaos P Daskalakis Andrew Ratanatharathorn Monica Uddin Caroline M Nievergelt Allison E Ashley-Koch Dewleen G Baker Jean C Beckham Melanie E Garrett Marco P Boks Elbert Geuze Gerald A Grant Michael A Hauser Ronald C Kessler Nathan A Kimbrel Adam X Maihofer Christine E Marx Xue-Jun Qin Victoria B Risbrough Bart P F Rutten Murray B Stein Robert J Ursano Eric Vermetten Christiaan H Vinkers Erin B Ware Annjanette Stone Steven A Schichman Regina E McGlinchey William P Milberg Jasmeet P Hayes Mieke Verfaellie

Clin Epigenetics 2020 03 14;12(1):46. Epub 2020 Mar 14.

Department of Psychiatry, Boston University School of Medicine, Boston, MA, USA.

View Article and Find Full Text PDF
March 2020

Prenatal antidepressant exposures and gastrointestinal complaints in childhood: A gut-brain axis connection?

Authors:
Amy L Salisbury George D Papandonatos Laura R Stroud Alicia K Smith Patricia A Brennan

Dev Psychobiol 2020 09 13;62(6):816-828. Epub 2020 Mar 13.

Department of Psychology, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
September 2020

Examining Reproductive Health Outcomes in Females Exposed to Polychlorinated Biphenyl and Polybrominated Biphenyl.

Authors:
Michael F Neblett Sarah W Curtis Sabrina A Gerkowicz Jessica B Spencer Metrecia L Terrell Victoria S Jiang M Elizabeth Marder Dana Boyd Barr Michele Marcus Alicia K Smith

Sci Rep 2020 02 24;10(1):3314. Epub 2020 Feb 24.

Department of Gynecology and Obstetrics, Emory University School of Medicine, 101 Woodruff Circle NE, Ste 4217, Atlanta, GA, 30322, Georgia.

View Article and Find Full Text PDF
February 2020

Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder.

Authors:
Clara Snijders Adam X Maihofer Andrew Ratanatharathorn Dewleen G Baker Marco P Boks Elbert Geuze Sonia Jain Ronald C Kessler Ehsan Pishva Victoria B Risbrough Murray B Stein Robert J Ursano Eric Vermetten Christiaan H Vinkers Alicia K Smith Monica Uddin Bart P F Rutten Caroline M Nievergelt

Clin Epigenetics 2020 01 13;12(1):11. Epub 2020 Jan 13.

Department of Psychiatry and Neuropsychology, School for Mental health and Neuroscience, Maastricht University, Maastricht, Limburg, Netherlands.

View Article and Find Full Text PDF
January 2020

Epigenetic modification of the oxytocin receptor gene: implications for autism symptom severity and brain functional connectivity.

Authors:
Elissar Andari Shota Nishitani Gopinath Kaundinya Gabriella A Caceres Michael J Morrier Opal Ousley Alicia K Smith Joseph F Cubells Larry J Young

Neuropsychopharmacology 2020 06 13;45(7):1150-1158. Epub 2020 Jan 13.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.

View Article and Find Full Text PDF
June 2020

DNA methylation biomarkers prospectively predict both antenatal and postpartum depression.

Authors:
Jennifer L Payne Lauren M Osborne Olivia Cox John Kelly Samantha Meilman Ilenna Jones Winston Grenier Karen Clark Evelyn Ross Rachel McGinn Pathik D Wadhwa Sonja Entringer Anne L Dunlop Anna K Knight Alicia K Smith Claudia Buss Zachary A Kaminsky

Psychiatry Res 2020 03 27;285:112711. Epub 2019 Nov 27.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA; The Royal's Institute of Mental Health Research, University of Ottawa, 1145 Carling Avenue, Rm, 6458 Ottawa, Ontario, Canada; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada. Electronic address:

View Article and Find Full Text PDF
March 2020

Stability of the vaginal, oral, and gut microbiota across pregnancy among African American women: the effect of socioeconomic status and antibiotic exposure.

Authors:
Anne L Dunlop Anna K Knight Glen A Satten Anya J Cutler Michelle L Wright Rebecca M Mitchell Timothy D Read Jennifer Mulle Vicki S Hertzberg Cherie C Hill Alicia K Smith Elizabeth J Corwin

PeerJ 2019 21;7:e8004. Epub 2019 Nov 21.

Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States of America.

View Article and Find Full Text PDF
November 2019

Critical evaluation of copy number variant calling methods using DNA methylation.

Authors:
Varun Kilaru Anna K Knight Seyma Katrinli Dawayland Cobb Adriana Lori Charles F Gillespie Adam X Maihofer Caroline M Nievergelt Anne L Dunlop Karen N Conneely Alicia K Smith

Genet Epidemiol 2020 03 18;44(2):148-158. Epub 2019 Nov 18.

Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.

View Article and Find Full Text PDF
March 2020

Successful treatment of post-traumatic stress disorder reverses DNA methylation marks.

Authors:
Christiaan H Vinkers Elbert Geuze Sanne J H van Rooij Mitzy Kennis Remmelt R Schür Danny M Nispeling Alicia K Smith Caroline M Nievergelt Monica Uddin Bart P F Rutten Eric Vermetten Marco P Boks

Mol Psychiatry 2019 Oct 23. Epub 2019 Oct 23.

UMC Utrecht Brain Center, University Utrecht, Utrecht, The Netherlands.

View Article and Find Full Text PDF
October 2019

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Authors:
Caroline M Nievergelt Adam X Maihofer Torsten Klengel Elizabeth G Atkinson Chia-Yen Chen Karmel W Choi Jonathan R I Coleman Shareefa Dalvie Laramie E Duncan Joel Gelernter Daniel F Levey Mark W Logue Renato Polimanti Allison C Provost Andrew Ratanatharathorn Murray B Stein Katy Torres Allison E Aiello Lynn M Almli Ananda B Amstadter Søren B Andersen Ole A Andreassen Paul A Arbisi Allison E Ashley-Koch S Bryn Austin Esmina Avdibegovic Dragan Babić Marie Bækvad-Hansen Dewleen G Baker Jean C Beckham Laura J Bierut Jonathan I Bisson Marco P Boks Elizabeth A Bolger Anders D Børglum Bekh Bradley Megan Brashear Gerome Breen Richard A Bryant Angela C Bustamante Jonas Bybjerg-Grauholm Joseph R Calabrese José M Caldas-de-Almeida Anders M Dale Mark J Daly Nikolaos P Daskalakis Jürgen Deckert Douglas L Delahanty Michelle F Dennis Seth G Disner Katharina Domschke Alma Dzubur-Kulenovic Christopher R Erbes Alexandra Evans Lindsay A Farrer Norah C Feeny Janine D Flory David Forbes Carol E Franz Sandro Galea Melanie E Garrett Bizu Gelaye Elbert Geuze Charles Gillespie Aferdita Goci Uka Scott D Gordon Guia Guffanti Rasha Hammamieh Supriya Harnal Michael A Hauser Andrew C Heath Sian M J Hemmings David Michael Hougaard Miro Jakovljevic Marti Jett Eric Otto Johnson Ian Jones Tanja Jovanovic Xue-Jun Qin Angela G Junglen Karen-Inge Karstoft Milissa L Kaufman Ronald C Kessler Alaptagin Khan Nathan A Kimbrel Anthony P King Nastassja Koen Henry R Kranzler William S Kremen Bruce R Lawford Lauren A M Lebois Catrin E Lewis Sarah D Linnstaedt Adriana Lori Bozo Lugonja Jurjen J Luykx Michael J Lyons Jessica Maples-Keller Charles Marmar Alicia R Martin Nicholas G Martin Douglas Maurer Matig R Mavissakalian Alexander McFarlane Regina E McGlinchey Katie A McLaughlin Samuel A McLean Sarah McLeay Divya Mehta William P Milberg Mark W Miller Rajendra A Morey Charles Phillip Morris Ole Mors Preben B Mortensen Benjamin M Neale Elliot C Nelson Merete Nordentoft Sonya B Norman Meaghan O'Donnell Holly K Orcutt Matthew S Panizzon Edward S Peters Alan L Peterson Matthew Peverill Robert H Pietrzak Melissa A Polusny John P Rice Stephan Ripke Victoria B Risbrough Andrea L Roberts Alex O Rothbaum Barbara O Rothbaum Peter Roy-Byrne Ken Ruggiero Ariane Rung Bart P F Rutten Nancy L Saccone Sixto E Sanchez Dick Schijven Soraya Seedat Antonia V Seligowski Julia S Seng Christina M Sheerin Derrick Silove Alicia K Smith Jordan W Smoller Scott R Sponheim Dan J Stein Jennifer S Stevens Jennifer A Sumner Martin H Teicher Wesley K Thompson Edward Trapido Monica Uddin Robert J Ursano Leigh Luella van den Heuvel Miranda Van Hooff Eric Vermetten Christiaan H Vinkers Joanne Voisey Yunpeng Wang Zhewu Wang Thomas Werge Michelle A Williams Douglas E Williamson Sherry Winternitz Christiane Wolf Erika J Wolf Jonathan D Wolff Rachel Yehuda Ross McD Young Keith A Young Hongyu Zhao Lori A Zoellner Israel Liberzon Kerry J Ressler Magali Haas Karestan C Koenen

Nat Commun 2019 10 8;10(1):4558. Epub 2019 Oct 8.

Broad Institute of MIT and Harvard, Stanley Center for Psychiatric Research, Cambridge, MA, USA.

View Article and Find Full Text PDF
October 2019

Adverse Childhood Experiences: Implications for Offspring Telomere Length and Psychopathology.

Authors:
Kyle C Esteves Christopher W Jones Mark Wade Keegan Callerame Alicia K Smith Katherine P Theall Stacy S Drury

Am J Psychiatry 2020 01 6;177(1):47-57. Epub 2019 Sep 6.

The Department of Psychiatry and Behavioral Sciences, Tulane University School of Medicine, New Orleans (Esteves, Drury); the Department of Neuroscience, Tulane Brain Institute, Tulane University, New Orleans (Jones, Drury); the Department of Applied Psychology and Human Development, University of Toronto (Wade); the Department of Cell and Molecular Biology, Tulane University, New Orleans (Callerame); the Department of Obstetrics and Gynecology, Emory University, Atlanta (Smith); and the Department of Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, Tulane University, New Orleans (Theall).

View Article and Find Full Text PDF
January 2020

Trauma, psychiatric disorders, and treatment history among pregnant African American women.

Authors:
Abigail Powers Briana Woods-Jaeger Jennifer S Stevens Bekh Bradley Misti B Patel Andrea Joyner Alicia K Smith Denise J Jamieson Nadine Kaslow Vasiliki Michopoulos

Psychol Trauma 2020 Feb 29;12(2):138-146. Epub 2019 Aug 29.

Department of Psychiatry and Behavioral Sciences.

View Article and Find Full Text PDF
February 2020

Thyroid hormone levels associate with exposure to polychlorinated biphenyls and polybrominated biphenyls in adults exposed as children.

Authors:
Sarah W Curtis Metrecia L Terrell Melanie H Jacobson Dawayland O Cobb Victoria S Jiang Michael F Neblett Sabrina A Gerkowicz Jessica B Spencer M Elizabeth Marder Dana Boyd Barr Karen N Conneely Alicia K Smith Michele Marcus

Environ Health 2019 08 23;18(1):75. Epub 2019 Aug 23.

Emory University Rollins School of Public Health, 1518 Clifton Rd, Atlanta, GA, 30322, USA.

View Article and Find Full Text PDF
August 2019

Environmental exposure to polybrominated biphenyl (PBB) associates with an increased rate of biological aging.

Authors:
Sarah W Curtis Dawayland O Cobb Varun Kilaru Metrecia L Terrell M Elizabeth Marder Dana Boyd Barr Carmen J Marsit Michele Marcus Karen N Conneely Alicia K Smith

Aging (Albany NY) 2019 08 2;11(15):5498-5517. Epub 2019 Aug 2.

Department of Gynecology and Obstetrics, School of Medicine, Emory University, Atlanta, GA 30322, USA.

View Article and Find Full Text PDF
August 2019

Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD.

Authors:
Maya A Lebow Mariana Schroeder Michael Tsoory Dorin Holzman-Karniel Divya Mehta Shifra Ben-Dor Shosh Gil Bekh Bradley Alicia K Smith Tanja Jovanovic Kerry J Ressler Elisabeth B Binder Alon Chen

Transl Psychiatry 2019 07 25;9(1):178. Epub 2019 Jul 25.

Department of Neurobiology, Weizmann Institute of Science, 76100, Rehovot, Israel.

View Article and Find Full Text PDF
July 2019

Protocol for the Emory University African American maternal stress and infant gut microbiome cohort study.

Authors:
Patricia A Brennan Anne L Dunlop Alicia K Smith Michael Kramer Jennifer Mulle Elizabeth J Corwin

BMC Pediatr 2019 07 22;19(1):246. Epub 2019 Jul 22.

Department of Psychology, Emory University, 36 Eagle Row, Atlanta, GA, 30322, USA.

View Article and Find Full Text PDF
July 2019

Childhood Adversity, Socioeconomic Instability, Oxytocin-Receptor-Gene Methylation, and Romantic-Relationship Support Among Young African American Men.

Authors:
Steven M Kogan Dayoung Bae Junhan Cho Alicia K Smith Shota Nishitani

Psychol Sci 2019 08 18;30(8):1234-1244. Epub 2019 Jul 18.

4 Department of Psychiatry and Behavioral Sciences, Emory University.

View Article and Find Full Text PDF
August 2019

Association of HLA locus alleles with posttraumatic stress disorder.

Authors:
Seyma Katrinli Adriana Lori Varun Kilaru Sierra Carter Abigail Powers Charles F Gillespie Aliza P Wingo Vasiliki Michopoulos Tanja Jovanovic Kerry J Ressler Alicia K Smith

Brain Behav Immun 2019 10 13;81:655-658. Epub 2019 Jul 13.

Emory University, Department of Gynecology and Obstetrics, Atlanta, GA, USA; Emory University, Department of Psychiatry & Behavioral Sciences, Atlanta, GA, USA. Electronic address:

View Article and Find Full Text PDF
October 2019

Correction for multiple testing in candidate-gene methylation studies.

Authors:
Zhenwei Zhou Kathryn L Lunetta Alicia K Smith Erika J Wolf Annjanette Stone Steven A Schichman Regina E McGlinchey William P Milberg Mark W Miller Mark W Logue

Epigenomics 2019 07 26;11(9):1089-1105. Epub 2019 Jun 26.

National Center for PTSD, VA Boston Healthcare System, Boston, MA 02130, USA.

View Article and Find Full Text PDF
July 2019

Methylomic profiles reveal sex-specific differences in leukocyte composition associated with post-traumatic stress disorder.

Authors:
Grace S Kim Alicia K Smith Fei Xue Vasiliki Michopoulos Adriana Lori Don L Armstrong Allison E Aiello Karestan C Koenen Sandro Galea Derek E Wildman Monica Uddin

Brain Behav Immun 2019 10 19;81:280-291. Epub 2019 Jun 19.

Genomics Program, College of Public Health, University of South Florida, Tampa, FL, USA. Electronic address:

View Article and Find Full Text PDF
October 2019

Exposure to polybrominated biphenyl and stochastic epigenetic mutations: application of a novel epigenetic approach to environmental exposure in the Michigan polybrominated biphenyl registry.

Authors:
Sarah W Curtis Dawayland O Cobb Varun Kilaru Metrecia L Terrell M Elizabeth Marder Dana Boyd Barr Carmen J Marsit Michele Marcus Karen N Conneely Alicia K Smith

Epigenetics 2019 10 14;14(10):1003-1018. Epub 2019 Jun 14.

g Departments of Gynecology and Obstetrics & Psychiatry and Behavioral Science, Emory University School of Medicine , Atlanta , GA , USA.

View Article and Find Full Text PDF
October 2019

Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.

Authors:
Anthony S Zannas Meiwen Jia Kathrin Hafner Jens Baumert Tobias Wiechmann Julius C Pape Janine Arloth Maik Ködel Silvia Martinelli Maria Roitman Simone Röh Andreas Haehle Rebecca T Emeny Stella Iurato Tania Carrillo-Roa Jari Lahti Katri Räikkönen Johan G Eriksson Amanda J Drake Melanie Waldenberger Simone Wahl Sonja Kunze Susanne Lucae Bekh Bradley Christian Gieger Felix Hausch Alicia K Smith Kerry J Ressler Bertram Müller-Myhsok Karl-Heinz Ladwig Theo Rein Nils C Gassen Elisabeth B Binder

Proc Natl Acad Sci U S A 2019 06 21;116(23):11370-11379. Epub 2019 May 21.

Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, 80804 Munich, Germany;

View Article and Find Full Text PDF
June 2019

Oxytocin receptor DNA methylation and alterations of brain volumes in maltreated children.

Authors:
Takashi X Fujisawa Shota Nishitani Shinichiro Takiguchi Koji Shimada Alicia K Smith Akemi Tomoda

Neuropsychopharmacology 2019 11 9;44(12):2045-2053. Epub 2019 May 9.

Research Center for Child Mental Development, University of Fukui, Fukui, Japan.

View Article and Find Full Text PDF
November 2019

Decidual cells from women with preeclampsia exhibit inadequate decidualization and reduced sFlt1 suppression.

Authors:
Margaret B Sahu Venkataraman Deepak Stephen K Gonzales Bassam Rimawi Keiana K Watkins Alicia K Smith Martina L Badell Neil Sidell Augustine Rajakumar

Pregnancy Hypertens 2019 Jan 17;15:64-71. Epub 2018 Nov 17.

Division of Research, Atlanta, GA, USA; Department of Gynecology and Obstetrics, Atlanta, GA, USA; Emory University School of Medicine, Atlanta, GA, USA. Electronic address:

View Article and Find Full Text PDF
January 2019

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation.

Authors:
Hari K Somineni Suresh Venkateswaran Varun Kilaru Urko M Marigorta Angela Mo David T Okou Richard Kellermayer Kajari Mondal Dawayland Cobb Thomas D Walters Anne Griffiths Joshua D Noe Wallace V Crandall Joel R Rosh David R Mack Melvin B Heyman Susan S Baker Michael C Stephens Robert N Baldassano James F Markowitz Marla C Dubinsky Judy Cho Jeffrey S Hyams Lee A Denson Greg Gibson David J Cutler Karen N Conneely Alicia K Smith Subra Kugathasan

Gastroenterology 2019 06 16;156(8):2254-2265.e3. Epub 2019 Feb 16.

Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia; Department of Human Genetics, Emory University, Atlanta, Georgia. Electronic address:

View Article and Find Full Text PDF
June 2019

School-age social behavior and pragmatic language ability in children with prenatal serotonin reuptake inhibitor exposure.

Authors:
Erica L Smearman Cassandra L Hendrix Dominika A Winiarski Katrina C Johnson Alicia K Smith Opal Y Ousley Zachary N Stowe D Jeffrey Newport Patricia A Brennan

Dev Psychopathol 2020 02;32(1):21-30

Department of Psychology, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
February 2020

Dynamic Patterns of Threat-Associated Gene Expression in the Amygdala and Blood.

Authors:
Adriana Lori Stephanie A Maddox Sumeet Sharma Raül Andero Kerry J Ressler Alicia K Smith

Front Psychiatry 2018 17;9:778. Epub 2019 Jan 17.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.

View Article and Find Full Text PDF
January 2019

Exposure to polybrominated biphenyl (PBB) associates with genome-wide DNA methylation differences in peripheral blood.

Authors:
Sarah W Curtis Dawayland O Cobb Varun Kilaru Metrecia L Terrell Elizabeth M Kennedy M Elizabeth Marder Dana Boyd Barr Carmen J Marsit Michele Marcus Karen N Conneely Alicia K Smith

Epigenetics 2019 01 24;14(1):52-66. Epub 2019 Jan 24.

a Genetics and Molecular Biology Program, Laney Graduate SchoolLaney Graduate School , Emory University School of Medicine , Atlanta , GA , USA.

View Article and Find Full Text PDF
January 2019

OXTR methylation modulates exogenous oxytocin effects on human brain activity during social interaction.

Authors:
Xu Chen Shota Nishitani Ebrahim Haroon Alicia K Smith James K Rilling

Genes Brain Behav 2020 01 10;19(1):e12555. Epub 2019 Feb 10.

Department of Anthropology, Emory University, Atlanta, Georgia.

View Article and Find Full Text PDF
January 2020

DNA Methylation Changes in Whole Blood and CD16+ Neutrophils in Response to Chronic Folic Acid Supplementation in Women of Childbearing Age.

Authors:
Deanna C Shade Hea Jin Park Dorothy B Hausman Natalie Hohos Richard B Meagher Gail P A Kauwell Varun Kilaru Richard D Lewis Alicia K Smith Lynn B Bailey

Int J Vitam Nutr Res 2017 Sep 30;87(5-6):271-278. Epub 2018 Nov 30.

1 Department of Foods and Nutrition, University of Georgia, Athens, GA, USA.

View Article and Find Full Text PDF
September 2017

Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies.

Authors:
Eline J Kraaijenvanger Yujie He Hannah Spencer Alicia K Smith Peter A Bos Marco P M Boks

Neurosci Biobehav Rev 2019 01 26;96:127-142. Epub 2018 Nov 26.

Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, the Netherlands.

View Article and Find Full Text PDF
January 2019

Associations Between Features of Placental Morphology and Birth Weight in Dichorionic Twins.

Authors:
Alexa A Freedman Carol J Hogue Carmen J Marsit Augustine Rajakumar Alicia K Smith Katherine L Grantz Robert L Goldenberg Donald J Dudley George R Saade Robert M Silver Karen J Gibbins Radek Bukowski Carolyn Drews-Botsch

Am J Epidemiol 2019 03;188(3):518-526

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.

View Article and Find Full Text PDF
March 2019

Association between one-carbon metabolism indices and DNA methylation status in maternal and cord blood.

Authors:
Anna K Knight Hea Jin Park Dorothy B Hausman Jennifer M Fleming Victoria L Bland Gisselle Rosa Elizabeth M Kennedy Marie A Caudill Olga Malysheva Gail P A Kauwell Andrew Sokolow Susan Fisher Alicia K Smith Lynn B Bailey

Sci Rep 2018 11 15;8(1):16873. Epub 2018 Nov 15.

Department of Foods and Nutrition, University of Georgia, Athens, GA, USA.

View Article and Find Full Text PDF
November 2018

Impact of male partner characteristics and semen parameters on in vitro fertilization and obstetric outcomes in a frozen oocyte donor model.

Authors:
Sarah M Capelouto Zsolt Peter Nagy Daniel B Shapiro Sydney R Archer Deandrea P Ellis Alicia K Smith Jessica B Spencer Heather S Hipp

Fertil Steril 2018 10;110(5):859-869

Division of Reproductive Endocrinology & Infertility, Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia.

View Article and Find Full Text PDF
October 2018

Oxytocin receptor gene methylation and substance use problems among young African American men.

Authors:
Steven M Kogan Junhan Cho Steven R H Beach Alicia K Smith Shota Nishitani

Drug Alcohol Depend 2018 11 4;192:309-315. Epub 2018 Oct 4.

Department of Gynecology and Obstetrics, Emory University School of Medicine, 101 Woodruff Circle, Suite 4217, Atlanta, GA, 30322, USA. Electronic address:

View Article and Find Full Text PDF
November 2018

Characterization of gene expression changes over healthy term pregnancies.

Authors:
Anna K Knight Anne L Dunlop Varun Kilaru Dawayland Cobb Elizabeth J Corwin Karen N Conneely Alicia K Smith

PLoS One 2018 10;13(10):e0204228. Epub 2018 Oct 10.

Genetics and Molecular Biology Program, Emory University, Atlanta, GA, United States of America.

View Article and Find Full Text PDF
March 2019

Comparison of diameter-based and image-based measures of surface area from gross placental pathology for use in epidemiologic studies.

Authors:
Alexa A Freedman Lauren M Kipling Katie Labgold Carmen J Marsit Carol J Hogue Augustine Rajakumar Alicia K Smith Halit Pinar Deborah L Conway Radek Bukowski Michael W Varner Robert L Goldenberg Donald J Dudley Carolyn Drews-Botsch

Placenta 2018 09 27;69:82-85. Epub 2018 Jul 27.

Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
September 2018

Maternal Trauma Exposure and Childhood Anxiety Outcomes: Examining Psychosocial Mechanisms of Risk.

Authors:
Brittany A Robinson Cassandra L Hendrix H Sloan Krakovsky Alicia K Smith Patricia A Brennan

J Abnorm Child Psychol 2019 04;47(4):645-657

Department of Psychology, Emory University, 36 Eagle Row, Atlanta, GA, 30322, USA.

View Article and Find Full Text PDF
April 2019

Neuroepigenetics of Post-Traumatic Stress Disorder.

Authors:
Grace S Kim Alicia K Smith Caroline M Nievergelt Monica Uddin

Prog Mol Biol Transl Sci 2018 29;158:227-253. Epub 2018 May 29.

Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, United States; Department of Psychology, University of Illinois at Urbana-Champaign, Urbana, IL, United States; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, United States. Electronic address:

View Article and Find Full Text PDF
July 2019

Associations Between the Features of Gross Placental Morphology and Birthweight.

Authors:
Alexa A Freedman Carol J Hogue Carmen J Marsit Augustine Rajakumar Alicia K Smith Robert L Goldenberg Donald J Dudley George R Saade Robert M Silver Karen J Gibbins Barbara J Stoll Radek Bukowski Carolyn Drews-Botsch

Pediatr Dev Pathol 2019 May-Jun;22(3):194-204. Epub 2018 Jul 16.

1 Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.

View Article and Find Full Text PDF
September 2019

Epigenetic Modification of is Associated with Openness to Experience.

Authors:
Brian W Haas Alicia K Smith Shota Nishitani

Personal Neurosci 2018 18;1:e7. Epub 2018 Jul 18.

Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.

View Article and Find Full Text PDF
July 2018

CD4 and CD8 T-Cell-Specific DNA Cytosine Methylation Differences Associated With Obesity.

Authors:
Natalie M Hohos Alicia K Smith Varun Kilaru Hea Jin Park Dorothy B Hausman Lynn B Bailey Richard D Lewis Bradley G Phillips Richard B Meagher

Obesity (Silver Spring) 2018 08 28;26(8):1312-1321. Epub 2018 Jun 28.

Department of Genetics, University of Georgia, Athens, Georgia, USA.

View Article and Find Full Text PDF
August 2018

An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells.

Authors:
Elizabeth M Kennedy George N Goehring Michael H Nichols Chloe Robins Divya Mehta Torsten Klengel Eleazar Eskin Alicia K Smith Karen N Conneely

BMC Genomics 2018 Jun 19;19(1):476. Epub 2018 Jun 19.

Genetics and Molecular Biology Program, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
June 2018

DNA methylation analysis from saliva samples for epidemiological studies.

Authors:
Shota Nishitani Sasha E Parets Brian W Haas Alicia K Smith

Epigenetics 2018 1;13(4):352-362. Epub 2018 Aug 1.

a Department of Gynecology and Obstetrics , Emory University School of Medicine , Atlanta , GA , USA.

View Article and Find Full Text PDF
February 2019

Intergenerational effects of endocrine-disrupting compounds: a review of the Michigan polybrominated biphenyl registry.

Authors:
Sarah W Curtis Karen N Conneely Mary E Marder Metrecia L Terrell Michele Marcus Alicia K Smith

Epigenomics 2018 06 11;10(6):845-858. Epub 2018 Jun 11.

Genetics and Molecular Biology Program, Emory University, Atlanta, GA 30322, USA.

View Article and Find Full Text PDF
June 2018

Maternal depression and cortisol in pregnancy predict offspring emotional reactivity in the preschool period.

Authors:
Danielle A Swales Dominika A Winiarski Alicia K Smith Zachary N Stowe D Jeffrey Newport Patricia A Brennan

Dev Psychobiol 2018 07 25;60(5):557-566. Epub 2018 May 25.

Department of Psychology, Emory University, Atlanta, Georgia.

View Article and Find Full Text PDF
July 2018

Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.

Authors:
Anthony S Zannas Janine Arloth Tania Carrillo-Roa Stella Iurato Simone Röh Kerry J Ressler Charles B Nemeroff Alicia K Smith Bekh Bradley Christine Heim Andreas Menke Jennifer F Lange Tanja Brückl Marcus Ising Naomi R Wray Angelika Erhardt Elisabeth B Binder Divya Mehta

Genome Biol 2018 05 23;19(1):61. Epub 2018 May 23.

The University of Queensland, Queensland Brain Institute, St Lucia, Australia.

View Article and Find Full Text PDF
May 2018

The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems.

Authors:
Anna Suarez Jari Lahti Darina Czamara Marius Lahti-Pulkkinen Anna K Knight Polina Girchenko Esa Hämäläinen Eero Kajantie Jari Lipsanen Hannele Laivuori Pia M Villa Rebecca M Reynolds Alicia K Smith Elisabeth B Binder Katri Räikkönen

J Am Acad Child Adolesc Psychiatry 2018 05 15;57(5):321-328.e2. Epub 2018 Mar 15.

University of Helsinki, Finland.

View Article and Find Full Text PDF
May 2018

Relationship between Epigenetic Maturity and Respiratory Morbidity in Preterm Infants.

Authors:
Anna K Knight Alicia K Smith Karen N Conneely Philippa Dalach Yuk J Loke Jeanie L Cheong Peter G Davis Jeffrey M Craig Lex W Doyle Christiane Theda

J Pediatr 2018 07 25;198:168-173.e2. Epub 2018 Apr 25.

Murdoch Childrens Research Institute, Melbourne, Victoria, Australia; Department of Obstetrics and Gynecology, University of Melbourne, Melbourne, Victoria, Australia; Neonatal Research, The Royal Women's Hospital, Melbourne, Victoria, Australia.

View Article and Find Full Text PDF
July 2018

Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative.

Authors:
Caroline M Nievergelt Allison E Ashley-Koch Shareefa Dalvie Michael A Hauser Rajendra A Morey Alicia K Smith Monica Uddin

Biol Psychiatry 2018 05 2;83(10):831-839. Epub 2018 Feb 2.

Carl R. Woese Institute for Genomic Biology, University of Illinois-Urbana-Champaign, Champaign, Illinois; Department of Psychology, University of Illinois-Urbana-Champaign, Champaign, Illinois.

View Article and Find Full Text PDF
May 2018

Traumatic stress and accelerated DNA methylation age: A meta-analysis.

Authors:
Erika J Wolf Hannah Maniates Nicole Nugent Adam X Maihofer Don Armstrong Andrew Ratanatharathorn Allison E Ashley-Koch Melanie Garrett Nathan A Kimbrel Adriana Lori Va Mid-Atlantic Mirecc Workgroup Allison E Aiello Dewleen G Baker Jean C Beckham Marco P Boks Sandro Galea Elbert Geuze Michael A Hauser Ronald C Kessler Karestan C Koenen Mark W Miller Kerry J Ressler Victoria Risbrough Bart P F Rutten Murray B Stein Robert J Ursano Eric Vermetten Christiaan H Vinkers Monica Uddin Alicia K Smith Caroline M Nievergelt Mark W Logue

Psychoneuroendocrinology 2018 06 27;92:123-134. Epub 2017 Dec 27.

National Center for PTSD at VA Boston Healthcare System, United States; Department of Psychiatry, Boston University School of Medicine, United States; Biomedical Genetics, Boston University School of Medicine, United States.

View Article and Find Full Text PDF
June 2018

SLC9B1 methylation predicts fetal intolerance of labor.

Authors:
Anna K Knight Karen N Conneely Varun Kilaru Dawayland Cobb Jennifer L Payne Samantha Meilman Elizabeth J Corwin Zachary A Kaminsky Anne L Dunlop Alicia K Smith

Epigenetics 2018 25;13(1):33-39. Epub 2018 Jan 25.

a Genetics and Molecular Biology Program , Emory University , 1462 Clifton Road, Atlanta , GA , 30322.

View Article and Find Full Text PDF
December 2018

Problematic alcohol use associates with sodium channel and clathrin linker 1 (SCLT1) in trauma-exposed populations.

Authors:
Lynn M Almli Adriana Lori Jacquelyn L Meyers Jaemin Shin Negar Fani Adam X Maihofer Caroline M Nievergelt Alicia K Smith Kristina B Mercer Kimberly Kerley Jennifer M Leveille Hao Feng Duna Abu-Amara Janine D Flory Rachel Yehuda Charles R Marmar Dewleen G Baker Bekh Bradley Karestan C Koenen Karen N Conneely Kerry J Ressler

Addict Biol 2018 09 30;23(5):1145-1159. Epub 2017 Oct 30.

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
September 2018

Serum Polybrominated Biphenyls (PBBs) and Polychlorinated Biphenyls (PCBs) and Thyroid Function among Michigan Adults Several Decades after the 1973-1974 PBB Contamination of Livestock Feed.

Authors:
Melanie H Jacobson Lyndsey A Darrow Dana Boyd Barr Penelope P Howards Robert H Lyles Metrecia L Terrell Alicia K Smith Karen N Conneely M Elizabeth Marder Michele Marcus

Environ Health Perspect 2017 09 26;125(9):097020. Epub 2017 Sep 26.

Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University , Atlanta, Georgia, USA.

View Article and Find Full Text PDF
September 2017

Exposure to Violence Accelerates Epigenetic Aging in Children.

Authors:
Tanja Jovanovic L Alexander Vance Dorthie Cross Anna K Knight Varun Kilaru Vasiliki Michopoulos Torsten Klengel Alicia K Smith

Sci Rep 2017 08 21;7(1):8962. Epub 2017 Aug 21.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 101 Woodruff Circle NE (Clifton RD NE), Atlanta, GA, 30322, USA.

View Article and Find Full Text PDF
August 2017

The correlation of methylation levels measured using Illumina 450K and EPIC BeadChips in blood samples.

Authors:
Mark W Logue Alicia K Smith Erika J Wolf Hannah Maniates Annjanette Stone Steven A Schichman Regina E McGlinchey William Milberg Mark W Miller

Epigenomics 2017 11 15;9(11):1363-1371. Epub 2017 Aug 15.

National Center for PTSD, VA Boston Healthcare System, USA.

View Article and Find Full Text PDF
November 2017

Distinctions in gene-specific changes in DNA methylation in response to folic acid supplementation between women with normal weight and obesity.

Authors:
Hea Jin Park Lynn B Bailey Deanna C Shade Dorothy B Hausman Natalie M Hohos Richard B Meagher Gail Pa Kauwell Richard D Lewis Alicia K Smith

Obes Res Clin Pract 2017 Nov - Dec;11(6):665-676. Epub 2017 Jul 18.

Psychiatry and Behavioral Sciences, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
June 2018

A Gene-Based Analysis of Acoustic Startle Latency.

Authors:
Alicia K Smith Tanja Jovanovic Varun Kilaru Adriana Lori Lauren Gensler Samuel S Lee Seth Davin Norrholm Nicholas Massa Bruce Cuthbert Bekh Bradley Kerry J Ressler Erica Duncan

Front Psychiatry 2017 6;8:117. Epub 2017 Jul 6.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, United States.

View Article and Find Full Text PDF
July 2017

Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.

Authors:
Andrew Ratanatharathorn Marco P Boks Adam X Maihofer Allison E Aiello Ananda B Amstadter Allison E Ashley-Koch Dewleen G Baker Jean C Beckham Evelyn Bromet Michelle Dennis Melanie E Garrett Elbert Geuze Guia Guffanti Michael A Hauser Varun Kilaru Nathan A Kimbrel Karestan C Koenen Pei-Fen Kuan Mark W Logue Benjamin J Luft Mark W Miller Colter Mitchell Nicole R Nugent Kerry J Ressler Bart P F Rutten Murray B Stein Eric Vermetten Christiaan H Vinkers Nagy A Youssef Monica Uddin Caroline M Nievergelt Alicia K Smith

Am J Med Genet B Neuropsychiatr Genet 2017 Sep 10;174(6):619-630. Epub 2017 Jul 10.

Department of Gynecology and Obstetrics, Emory University, Atlanta, Georgia.

View Article and Find Full Text PDF
September 2017

Methylation differences reveal heterogeneity in preterm pathophysiology: results from bipartite network analyses.

Authors:
Suresh K Bhavnani Bryant Dang Varun Kilaru Maria Caro Shyam Visweswaran George Saade Alicia K Smith Ramkumar Menon

J Perinat Med 2018 Jul;46(5):509-521

Department of Obstetrics and Gynecology, Division of Maternal Fetal-Medicine Perinatal Research, The University of Texas Medical Branch, MRB 11.138, 301 University Blvd, Galveston, TX 77555,USA.

View Article and Find Full Text PDF
July 2018

Locus-specific DNA methylation changes and phenotypic variability in children with attention-deficit hyperactivity disorder.

Authors:
Sarojini M Sengupta Alicia K Smith Natalie Grizenko Ridha Joober

Psychiatry Res 2017 10 20;256:298-304. Epub 2017 Jun 20.

Douglas Mental Health University Institute, Verdun, Quebec, Canada; Department of Psychiatry, McGill University, Montreal, Quebec, Canada; Department of Human Genetics, McGill University, Montreal, Quebec, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada.

View Article and Find Full Text PDF
October 2017

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth.

Authors:
Polina Girchenko Jari Lahti Darina Czamara Anna K Knight Meaghan J Jones Anna Suarez Esa Hämäläinen Eero Kajantie Hannele Laivuori Pia M Villa Rebecca M Reynolds Michael S Kobor Alicia K Smith Elisabeth B Binder Katri Räikkönen

Clin Epigenetics 2017 8;9:49. Epub 2017 May 8.

Institute of Behavioral Sciences, University of Helsinki, Helsinki, 00014 Finland.

View Article and Find Full Text PDF
March 2018

Comparison of different cell type correction methods for genome-scale epigenetics studies.

Authors:
Akhilesh Kaushal Hongmei Zhang Wilfried J J Karmaus Meredith Ray Mylin A Torres Alicia K Smith Shu-Li Wang

BMC Bioinformatics 2017 Apr 14;18(1):216. Epub 2017 Apr 14.

National Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli, Taiwan.

View Article and Find Full Text PDF
April 2017

Non-linear patterns in age-related DNA methylation may reflect CD4 T cell differentiation.

Authors:
Nicholas D Johnson Howard W Wiener Alicia K Smith Shota Nishitani Devin M Absher Donna K Arnett Stella Aslibekyan Karen N Conneely

Epigenetics 2017 06 7;12(6):492-503. Epub 2017 Apr 7.

a Department of Human Genetics , Emory University , Atlanta , GA , USA.

View Article and Find Full Text PDF
June 2017

The impact of psychological distress during pregnancy on the developing fetus: biological mechanisms and the potential benefits of mindfulness interventions.

Authors:
Monica Isgut Alicia K Smith Eduardo Schuch Reimann Omer Kucuk Joanne Ryan

J Perinat Med 2017 Dec;45(9):999-1011

.

View Article and Find Full Text PDF
December 2017

Gestational age predicted by DNA methylation: potential clinical and research utility.

Authors:
Anna K Knight Karen N Conneely Alicia K Smith

Epigenomics 2017 Jan 23. Epub 2017 Jan 23.

Genetics & Molecular Biology Program, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
January 2017

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.

Authors:
Symen Ligthart Carola Marzi Stella Aslibekyan Michael M Mendelson Karen N Conneely Toshiko Tanaka Elena Colicino Lindsay L Waite Roby Joehanes Weihua Guan Jennifer A Brody Cathy Elks Riccardo Marioni Min A Jhun Golareh Agha Jan Bressler Cavin K Ward-Caviness Brian H Chen Tianxiao Huan Kelly Bakulski Elias L Salfati Giovanni Fiorito Simone Wahl Katharina Schramm Jin Sha Dena G Hernandez Allan C Just Jennifer A Smith Nona Sotoodehnia Luke C Pilling James S Pankow Phil S Tsao Chunyu Liu Wei Zhao Simonetta Guarrera Vasiliki J Michopoulos Alicia K Smith Marjolein J Peters David Melzer Pantel Vokonas Myriam Fornage Holger Prokisch Joshua C Bis Audrey Y Chu Christian Herder Harald Grallert Chen Yao Sonia Shah Allan F McRae Honghuang Lin Steve Horvath Daniele Fallin Albert Hofman Nicholas J Wareham Kerri L Wiggins Andrew P Feinberg John M Starr Peter M Visscher Joanne M Murabito Sharon L R Kardia Devin M Absher Elisabeth B Binder Andrew B Singleton Stefania Bandinelli Annette Peters Melanie Waldenberger Giuseppe Matullo Joel D Schwartz Ellen W Demerath André G Uitterlinden Joyce B J van Meurs Oscar H Franco Yii-Der Ida Chen Daniel Levy Stephen T Turner Ian J Deary Kerry J Ressler Josée Dupuis Luigi Ferrucci Ken K Ong Themistocles L Assimes Eric Boerwinkle Wolfgang Koenig Donna K Arnett Andrea A Baccarelli Emelia J Benjamin Abbas Dehghan

Genome Biol 2016 12 12;17(1):255. Epub 2016 Dec 12.

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.

View Article and Find Full Text PDF
December 2016

Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation.

Authors:
Benjamin T Mayne Shalem Y Leemaqz Alicia K Smith James Breen Claire T Roberts Tina Bianco-Miotto

Epigenomics 2017 03 29;9(3):279-289. Epub 2016 Nov 29.

Robinson Research Institute, University of Adelaide, SA, 5005, Australia.

View Article and Find Full Text PDF
March 2017

Accelerated placental aging in early onset preeclampsia pregnancies identified by DNA methylation.

Authors:
Benjamin T Mayne Shalem Y Leemaqz Alicia K Smith James Breen Claire T Roberts Tina Bianco-Miotto

Epigenomics 2017 03 29;9(3):279-289. Epub 2016 Nov 29.

Robinson Research Institute, University of Adelaide, SA, 5005, Australia.

View Article and Find Full Text PDF
March 2017

Epigenetic Signatures of Cigarette Smoking.

Authors:
Roby Joehanes Allan C Just Riccardo E Marioni Luke C Pilling Lindsay M Reynolds Pooja R Mandaviya Weihua Guan Tao Xu Cathy E Elks Stella Aslibekyan Hortensia Moreno-Macias Jennifer A Smith Jennifer A Brody Radhika Dhingra Paul Yousefi James S Pankow Sonja Kunze Sonia H Shah Allan F McRae Kurt Lohman Jin Sha Devin M Absher Luigi Ferrucci Wei Zhao Ellen W Demerath Jan Bressler Megan L Grove Tianxiao Huan Chunyu Liu Michael M Mendelson Chen Yao Douglas P Kiel Annette Peters Rui Wang-Sattler Peter M Visscher Naomi R Wray John M Starr Jingzhong Ding Carlos J Rodriguez Nicholas J Wareham Marguerite R Irvin Degui Zhi Myrto Barrdahl Paolo Vineis Srikant Ambatipudi André G Uitterlinden Albert Hofman Joel Schwartz Elena Colicino Lifang Hou Pantel S Vokonas Dena G Hernandez Andrew B Singleton Stefania Bandinelli Stephen T Turner Erin B Ware Alicia K Smith Torsten Klengel Elisabeth B Binder Bruce M Psaty Kent D Taylor Sina A Gharib Brenton R Swenson Liming Liang Dawn L DeMeo George T O'Connor Zdenko Herceg Kerry J Ressler Karen N Conneely Nona Sotoodehnia Sharon L R Kardia David Melzer Andrea A Baccarelli Joyce B J van Meurs Isabelle Romieu Donna K Arnett Ken K Ong Yongmei Liu Melanie Waldenberger Ian J Deary Myriam Fornage Daniel Levy Stephanie J London

Circ Cardiovasc Genet 2016 Oct 20;9(5):436-447. Epub 2016 Sep 20.

View Article and Find Full Text PDF
October 2016

An epigenetic clock for gestational age at birth based on blood methylation data.

Authors:
Anna K Knight Jeffrey M Craig Christiane Theda Marie Bækvad-Hansen Jonas Bybjerg-Grauholm Christine S Hansen Mads V Hollegaard David M Hougaard Preben B Mortensen Shantel M Weinsheimer Thomas M Werge Patricia A Brennan Joseph F Cubells D Jeffrey Newport Zachary N Stowe Jeanie L Y Cheong Philippa Dalach Lex W Doyle Yuk J Loke Andrea A Baccarelli Allan C Just Robert O Wright Mara M Téllez-Rojo Katherine Svensson Letizia Trevisi Elizabeth M Kennedy Elisabeth B Binder Stella Iurato Darina Czamara Katri Räikkönen Jari M T Lahti Anu-Katriina Pesonen Eero Kajantie Pia M Villa Hannele Laivuori Esa Hämäläinen Hea Jin Park Lynn B Bailey Sasha E Parets Varun Kilaru Ramkumar Menon Steve Horvath Nicole R Bush Kaja Z LeWinn Frances A Tylavsky Karen N Conneely Alicia K Smith

Genome Biol 2016 10 7;17(1):206. Epub 2016 Oct 7.

Genetics and Molecular Biology Program, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
October 2016

Childhood Trauma and COMT Genotype Interact to Increase Hippocampal Activation in Resilient Individuals.

Authors:
Sanne J H van Rooij Jennifer S Stevens Timothy D Ely Negar Fani Alicia K Smith Kimberly A Kerley Adriana Lori Kerry J Ressler Tanja Jovanovic

Front Psychiatry 2016 14;7:156. Epub 2016 Sep 14.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine , Atlanta, GA , USA.

View Article and Find Full Text PDF
September 2016

Epigenetic modification of OXT and human sociability.

Authors:
Brian W Haas Megan M Filkowski R Nick Cochran Lydia Denison Alexandra Ishak Shota Nishitani Alicia K Smith

Proc Natl Acad Sci U S A 2016 07 20;113(27):E3816-23. Epub 2016 Jun 20.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA 30322;

View Article and Find Full Text PDF
July 2016

Maternal Prenatal Psychological Distress and Preschool Cognitive Functioning: the Protective Role of Positive Parental Engagement.

Authors:
Julia C Schechter Patricia A Brennan Alicia K Smith Zachary N Stowe D Jeffrey Newport Katrina C Johnson

J Abnorm Child Psychol 2017 02;45(2):249-260

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 201 Dowman Drive, Atlanta, GA, 30322, USA.

View Article and Find Full Text PDF
February 2017

Epigenetic Biomarkers of Preterm Birth and Its Risk Factors.

Authors:
Anna K Knight Alicia K Smith

Genes (Basel) 2016 Apr 13;7(4). Epub 2016 Apr 13.

Genetics and Molecular Biology Program, Emory University, Atlanta, GA 30322, USA.

View Article and Find Full Text PDF
April 2016

Corrigendum: DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.

Authors:
Aliza P Wingo Lynn M Almli Jennifer S Stevens Torsten Klengel Monica Uddin Yujing Li Angela C Bustamante Adriana Lori Nastassja Koen Dan J Stein Alicia K Smith Allison E Aiello Karestan C Koenen Derek E Wildman Sandro Galea Bekh Bradley Elisabeth B Binder Peng Jin Greg Gibson Kerry J Ressler

Nat Commun 2016 Mar 3;7:10958. Epub 2016 Mar 3.

View Article and Find Full Text PDF
March 2016

Preschool outcomes following prenatal serotonin reuptake inhibitor exposure: differences in language and behavior, but not cognitive function.

Authors:
Katrina C Johnson Alicia K Smith Zachary N Stowe D Jeffrey Newport Patricia A Brennan

J Clin Psychiatry 2016 Feb;77(2):e176-82

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia.

View Article and Find Full Text PDF
February 2016

Oxytocin Receptor Genetic and Epigenetic Variations: Association With Child Abuse and Adult Psychiatric Symptoms.

Authors:
Erica L Smearman Lynn M Almli Karen N Conneely Gene H Brody Jessica M Sales Bekh Bradley Kerry J Ressler Alicia K Smith

Child Dev 2016 Jan-Feb;87(1):122-34

Emory University School of Medicine.

View Article and Find Full Text PDF
December 2016

Insights into genetic susceptibility in the etiology of spontaneous preterm birth.

Authors:
Sasha E Parets Anna K Knight Alicia K Smith

Appl Clin Genet 2015 14;8:283-90. Epub 2015 Dec 14.

Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA ; Genetics and Molecular Biology Program, Emory University, Atlanta, GA, USA.

View Article and Find Full Text PDF
December 2015

Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling.

Authors:
Anthony S Zannas Janine Arloth Tania Carrillo-Roa Stella Iurato Simone Röh Kerry J Ressler Charles B Nemeroff Alicia K Smith Bekh Bradley Christine Heim Andreas Menke Jennifer F Lange Tanja Brückl Marcus Ising Naomi R Wray Angelika Erhardt Elisabeth B Binder Divya Mehta

Genome Biol 2015 Dec 17;16:266. Epub 2015 Dec 17.

The University of Queensland, Queensland Brain Institute, St Lucia, Qld 4072, Australia.

View Article and Find Full Text PDF
December 2015

DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression.

Authors:
Aliza P Wingo Lynn M Almli Jennifer S Stevens Jennifer J Stevens Torsten Klengel Monica Uddin Yujing Li Angela C Bustamante Adriana Lori Nastassja Koen Dan J Stein Alicia K Smith Allison E Aiello Karestan C Koenen Derek E Wildman Sandro Galea Bekh Bradley Elisabeth B Binder Peng Jin Greg Gibson Kerry J Ressler

Nat Commun 2015 Dec 3;6:10106. Epub 2015 Dec 3.

Department of Psychiatry, School of Medicine, Emory University, Atlanta, Georgia 30322, USA.

View Article and Find Full Text PDF
December 2015

The transcriptional landscape of age in human peripheral blood.

Authors:
Marjolein J Peters Roby Joehanes Luke C Pilling Claudia Schurmann Karen N Conneely Joseph Powell Eva Reinmaa George L Sutphin Alexandra Zhernakova Katharina Schramm Yana A Wilson Sayuko Kobes Taru Tukiainen Yolande F Ramos Harald H H Göring Myriam Fornage Yongmei Liu Sina A Gharib Barbara E Stranger Philip L De Jager Abraham Aviv Daniel Levy Joanne M Murabito Peter J Munson Tianxiao Huan Albert Hofman André G Uitterlinden Fernando Rivadeneira Jeroen van Rooij Lisette Stolk Linda Broer Michael M P J Verbiest Mila Jhamai Pascal Arp Andres Metspalu Liina Tserel Lili Milani Nilesh J Samani Pärt Peterson Silva Kasela Veryan Codd Annette Peters Cavin K Ward-Caviness Christian Herder Melanie Waldenberger Michael Roden Paula Singmann Sonja Zeilinger Thomas Illig Georg Homuth Hans-Jörgen Grabe Henry Völzke Leif Steil Thomas Kocher Anna Murray David Melzer Hanieh Yaghootkar Stefania Bandinelli Eric K Moses Jack W Kent Joanne E Curran Matthew P Johnson Sarah Williams-Blangero Harm-Jan Westra Allan F McRae Jennifer A Smith Sharon L R Kardia Iiris Hovatta Markus Perola Samuli Ripatti Veikko Salomaa Anjali K Henders Nicholas G Martin Alicia K Smith Divya Mehta Elisabeth B Binder K Maria Nylocks Elizabeth M Kennedy Torsten Klengel Jingzhong Ding Astrid M Suchy-Dicey Daniel A Enquobahrie Jennifer Brody Jerome I Rotter Yii-Der I Chen Jeanine Houwing-Duistermaat Margreet Kloppenburg P Eline Slagboom Quinta Helmer Wouter den Hollander Shannon Bean Towfique Raj Noman Bakhshi Qiao Ping Wang Lisa J Oyston Bruce M Psaty Russell P Tracy Grant W Montgomery Stephen T Turner John Blangero Ingrid Meulenbelt Kerry J Ressler Jian Yang Lude Franke Johannes Kettunen Peter M Visscher G Gregory Neely Ron Korstanje Robert L Hanson Holger Prokisch Luigi Ferrucci Tonu Esko Alexander Teumer Joyce B J van Meurs Andrew D Johnson

Nat Commun 2015 Oct 22;6:8570. Epub 2015 Oct 22.

The National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts 01702, USA.

View Article and Find Full Text PDF
October 2015

Down-regulation of PRKCB1 expression in Han Chinese patients with subsyndromal symptomatic depression.

Authors:
Xiaoyun Guo Zezhi Li Chen Zhang Zhenghui Yi Haozhe Li Lan Cao Chengmei Yuan Wu Hong Zhiguo Wu Daihui Peng Jun Chen Weiping Xia Guoqing Zhao Fan Wang Shunying Yu Donghong Cui Yifeng Xu Chowdhury M I Golam Alicia K Smith Tong Wang Yiru Fang

J Psychiatr Res 2015 Oct 17;69:1-6. Epub 2015 Jul 17.

Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

View Article and Find Full Text PDF
October 2015

DNA methylation provides insight into intergenerational risk for preterm birth in African Americans.

Authors:
Sasha E Parets Karen N Conneely Varun Kilaru Ramkumar Menon Alicia K Smith

Epigenetics 2015 19;10(9):784-92. Epub 2015 Jun 19.

a Genetics and Molecular Biology Program; Emory University ; Atlanta , GA USA.

View Article and Find Full Text PDF
June 2016

A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces.

Authors:
Lynn M Almli Jennifer S Stevens Alicia K Smith Varun Kilaru Qian Meng Janine Flory Duna Abu-Amara Rasha Hammamieh Ruoting Yang Kristina B Mercer Elizabeth B Binder Bekh Bradley Steven Hamilton Marti Jett Rachel Yehuda Charles R Marmar Kerry J Ressler

Am J Med Genet B Neuropsychiatr Genet 2015 Jul 18;168B(5):327-36. Epub 2015 May 18.

Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia.

View Article and Find Full Text PDF
July 2015

The Psychiatric Genomics Consortium Posttraumatic Stress Disorder Workgroup: Posttraumatic Stress Disorder Enters the Age of Large-Scale Genomic Collaboration.

Authors:
Mark W Logue Ananda B Amstadter Dewleen G Baker Laramie Duncan Karestan C Koenen Israel Liberzon Mark W Miller Rajendra A Morey Caroline M Nievergelt Kerry J Ressler Alicia K Smith Jordan W Smoller Murray B Stein Jennifer A Sumner Monica Uddin

Neuropsychopharmacology 2015 Sep 23;40(10):2287-97. Epub 2015 Apr 23.

1] Carl R Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA [2] Department of Psychology, University of Illinois Urbana-Champaign, Champaign, IL, USA.

View Article and Find Full Text PDF
September 2015