Alice Pébay

Alice Pébay

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Alice Pébay

Publications by authors named "Alice Pébay"

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Optimization of silk fibroin membranes for retinal implantation.

Mater Sci Eng C Mater Biol Appl 2019 Dec 29;105:110131. Epub 2019 Aug 29.

Queensland Eye Institute, South Brisbane, Queensland 4101, Australia; School of Biomedical Sciences and Institute of Health & Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland 4000, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2019.110131DOI Listing
December 2019

Human pluripotent stem cells for the modelling of diseases of the retina and optic nerve: toward a retina in a dish.

Curr Opin Pharmacol 2019 Oct 4;48:114-119. Epub 2019 Oct 4.

Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, Australia; Department of Surgery, The University of Melbourne, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2019.09.003DOI Listing
October 2019

Bio-engineering a tissue flap utilizing a porous scaffold incorporating a human induced pluripotent stem cell-derived endothelial cell capillary network connected to a vascular pedicle.

Acta Biomater 2019 Aug 30;94:281-294. Epub 2019 May 30.

O'Brien Institute Dept. of St Vincent's Institute, Melbourne, Australia; Univ. of Melbourne, Dept. of Surgery at St Vincent's Hospital, Melbourne, Australia; Faculty of Health Sciences, Australian Catholic University, Fitzroy, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.actbio.2019.05.067DOI Listing
August 2019

A Need for Better Understanding Is the Major Determinant for Public Perceptions of Human Gene Editing.

Hum Gene Ther 2019 Jan 3;30(1):36-43. Epub 2018 Oct 3.

1 Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1089/hum.2018.033DOI Listing
January 2019

The current state of stem cell therapy for ocular disease.

Exp Eye Res 2018 12 17;177:65-75. Epub 2018 Jul 17.

Prince of Wales Hospital Clinical School, High Street, Randwick, Sydney, New South Wales, 2031, Australia; Save Sight Institute, University of Sydney, 8 Macquarie Street, Sydney, New South Wales, 2000, Australia; Sydney Eye Hospital, 8 Macquarie Street, Sydney, New South Wales, 2000, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00144835183029
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http://dx.doi.org/10.1016/j.exer.2018.07.019DOI Listing
December 2018

Roles of lysophosphatidic acid and sphingosine-1-phosphate in stem cell biology.

Prog Lipid Res 2018 10 6;72:42-54. Epub 2018 Sep 6.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia; Ophthalmology, Department of Surgery, the University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.plipres.2018.09.001DOI Listing
October 2018

Single-Cell Profiling Identifies Key Pathways Expressed by iPSCs Cultured in Different Commercial Media.

iScience 2018 Sep 23;7:30-39. Epub 2018 Aug 23.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, 32 Gisborne Street, East Melbourne, VIC 3002, Australia; Ophthalmology, Department of Surgery, the University of Melbourne, Melbourne, VIC 3002, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S25890042183012
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http://dx.doi.org/10.1016/j.isci.2018.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135898PMC
September 2018

Automated Cell Culture Systems and Their Applications to Human Pluripotent Stem Cell Studies.

SLAS Technol 2018 08 2;23(4):315-325. Epub 2017 Jun 2.

1 Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1177/2472630317712220DOI Listing
August 2018

Maintenance of Human Embryonic Stem Cells by Sphingosine-1-Phosphate and Platelet-Derived Growth Factor.

Methods Mol Biol 2018 ;1697:133-140

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, The University of Melbourne, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.

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http://dx.doi.org/10.1007/7651_2017_4DOI Listing
July 2018

Role of lysophosphatidic acid in the retinal pigment epithelium and photoreceptors.

Biochim Biophys Acta Mol Cell Biol Lipids 2018 07 13;1863(7):750-761. Epub 2018 Apr 13.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Australia; Ophthalmology, Department of Surgery, The University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2018.04.007DOI Listing
July 2018

Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network.

Alzheimers Res Ther 2018 07 25;10(1):69. Epub 2018 Jul 25.

Department of Neuroscience and Department of Genetics and Genomic Sciences, Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY, 10029, USA.

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http://dx.doi.org/10.1186/s13195-018-0400-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060509PMC
July 2018

Development of a Modular Automated System for Maintenance and Differentiation of Adherent Human Pluripotent Stem Cells.

SLAS Discov 2017 09 13;22(8):1016-1025. Epub 2017 Mar 13.

1 Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital & Department of Ophthalmology, the University of Melbourne, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1177/2472555217696797DOI Listing
September 2017

Generation of a human induced pluripotent stem cell line CERAi001-A-6 using episomal vectors.

Stem Cell Res 2017 07 19;22:13-15. Epub 2017 May 19.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Australia; Ophthalmology, Department of Surgery, The University of Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2017.05.007DOI Listing
July 2017

Peeking into the molecular trove of discarded surgical specimens.

Clin Exp Ophthalmol 2016 Nov;44(8):661-662

Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/ceo.12837DOI Listing
November 2016

Role of ectonucleotide pyrophosphatase/phosphodiesterase 2 in the midline axis formation of zebrafish.

Sci Rep 2016 11 24;6:37678. Epub 2016 Nov 24.

Australian Regenerative Medicine Institute, Building 75, Monash University, Australia.

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http://dx.doi.org/10.1038/srep37678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121889PMC
November 2016

Enhancing Human Cardiomyocyte Differentiation from Induced Pluripotent Stem Cells with Trichostatin A.

Methods Mol Biol 2016 ;1357:415-21

Department of Surgery, O'Brien Institute, University of Melbourne, 42 Fitzroy Street, Fitzroy, VIC, 3065, Australia.

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http://dx.doi.org/10.1007/7651_2014_160DOI Listing
October 2016

ALPK3-deficient cardiomyocytes generated from patient-derived induced pluripotent stem cells and mutant human embryonic stem cells display abnormal calcium handling and establish that ALPK3 deficiency underlies familial cardiomyopathy.

Eur Heart J 2016 Sep 22;37(33):2586-90. Epub 2016 Apr 22.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Childrens Research Institute, Flemington Road, Parkville 3052, Victoria, Australia Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville 3052, Victoria, Australia

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http://dx.doi.org/10.1093/eurheartj/ehw160DOI Listing
September 2016

Participant understanding and recall of informed consent for induced pluripotent stem cell biobanking.

Cell Tissue Bank 2016 Sep 14;17(3):449-56. Epub 2016 Jun 14.

Department of Surgery, Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, 32 Gisborne Street, East Melbourne, VIC, Australia.

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http://dx.doi.org/10.1007/s10561-016-9563-8DOI Listing
September 2016

Enriched retinal ganglion cells derived from human embryonic stem cells.

Sci Rep 2016 08 10;6:30552. Epub 2016 Aug 10.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital &Ophthalmology, Department of Surgery, the University of Melbourne, Australia.

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http://dx.doi.org/10.1038/srep30552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978994PMC
August 2016

Genome engineering in ophthalmology: Application of CRISPR/Cas to the treatment of eye disease.

Prog Retin Eye Res 2016 07 13;53:1-20. Epub 2016 May 13.

Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Australia; Menzies Institute for Medical Research, School of Medicine, University of Tasmania, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.preteyeres.2016.05.001DOI Listing
July 2016

Using human pluripotent stem cells to study Friedreich ataxia cardiomyopathy.

Int J Cardiol 2016 Jun 21;212:37-43. Epub 2016 Mar 21.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Australia; Ophthalmology, Department of Surgery, The University of Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.03.040DOI Listing
June 2016

AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo.

Invest Ophthalmol Vis Sci 2016 Jun;57(7):3470-6

Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia 2Menzies Institute for Medical Research, School of Medicine, University of Tasmania, Hobart, Tasmania, Australia.

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http://dx.doi.org/10.1167/iovs.16-19316DOI Listing
June 2016

Study of Gap Junctions in Human Embryonic Stem Cells.

Methods Mol Biol 2016 ;1307:105-21

Department of Ophthalmology, Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Level 1 RVEEH, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia,

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http://dx.doi.org/10.1007/7651_2014_83DOI Listing
May 2016

Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells.

Aging (Albany NY) 2016 05;8(5):945-57

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital and Ophthalmology, Department of Surgery, The University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.18632/aging.100950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931846PMC
May 2016

A Global Social Media Survey of Attitudes to Human Genome Editing.

Cell Stem Cell 2016 05;18(5):569-72

Centre for Eye Research Australia, University of Melbourne, Melbourne, VIC 3002, Australia; Lions Eye Institute, University of Western Australia, Perth, WA 6150, Australia; Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS 7000, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.04.011DOI Listing
May 2016

Acute effect of endothelins on intercellular communication of human embryonic stem cells.

J Stem Cells 2009 ;4(1):47-56

Centre for Neuroscience, Department of Pharmacology, The University of Melbourne, Parkville, VIC 3010, Australia.

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http://dx.doi.org/jsc.2009.4.1.47DOI Listing
April 2016

Defined Medium Conditions for the Induction and Expansion of Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.

Stem Cell Rev Rep 2016 Apr;12(2):179-88

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital; Ophthalmology, University of Melbourne, Department of Surgery, 32 Gisborne Street, East Melbourne, VIC, 3002, Australia.

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http://dx.doi.org/10.1007/s12015-015-9636-2DOI Listing
April 2016

An Interactive Multimedia Approach to Improving Informed Consent for Induced Pluripotent Stem Cell Research.

Cell Stem Cell 2016 Mar;18(3):307-8

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital; University of Melbourne, Department of Surgery, 3002, VIC, Australia; Menzies Institute for Medical Research, School of Medicine, University of Tasmania, Hobart, 7000, TAS, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.02.006DOI Listing
March 2016

Electrical Stimulation Promotes Cardiac Differentiation of Human Induced Pluripotent Stem Cells.

Stem Cells Int 2016 14;2016:1718041. Epub 2015 Dec 14.

O'Brien Institute Department, St Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia; Department of Surgery, University of Melbourne, East Melbourne, VIC 3002, Australia.

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http://dx.doi.org/10.1155/2016/1718041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691644PMC
January 2016

Characterization of the retinal pigment epithelium in Friedreich ataxia.

Biochem Biophys Rep 2015 Dec 11;4:141-147. Epub 2015 Sep 11.

Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital & Department of Surgery, The University of Melbourne, East Melbourne, Australia.

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http://dx.doi.org/10.1016/j.bbrep.2015.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5668915PMC
December 2015

Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes.

J Vis Exp 2015 Aug 20(102):e53174. Epub 2015 Aug 20.

Centre for Eye Research Australia & Department of Ophthalmology, University of Melbourne;

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http://dx.doi.org/10.3791/53174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692540PMC
August 2015

Cell and gene therapy for Friedreich ataxia: progress to date.

Hum Gene Ther 2014 Aug 19;25(8):684-93. Epub 2014 Jun 19.

1 Bruce Lefroy Centre for Genetic Health Research, Murdoch Children's Research Institute , Parkville Victoria 3052, Australia .

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http://dx.doi.org/10.1089/hum.2013.180DOI Listing
August 2014

Human pluripotent stem cell strategies for age-related macular degeneration.

Optom Vis Sci 2014 Aug;91(8):887-93

*PhD †MD, PhD Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, and Department of Ophthalmology, the University of Melbourne, East Melbourne, Australia (KCD, RHG, AP); and Department of Anatomy and Neurosciences, the University of Melbourne, The Florey Institute of Neuroscience and Mental Health, Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia (MFP).

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http://dx.doi.org/10.1097/OPX.0000000000000282DOI Listing
August 2014

Complexities of lysophospholipid signalling in glioblastoma.

J Clin Neurosci 2014 Jun 18;21(6):893-8. Epub 2014 Apr 18.

University of Melbourne, Parkville, VIC, Australia; Department of Surgery, Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia; Department of Neurosurgery, Royal Melbourne Hospital, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2014.02.013DOI Listing
June 2014

Methods of Retinal Ganglion Cell Differentiation From Pluripotent Stem Cells.

Transl Vis Sci Technol 2014 May 1;3(4). Epub 2014 Jul 1.

Department of Ophthalmology, University of Melbourne, Melbourne East, VIC, Australia ; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital Melbourne East, VIC, Australia.

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http://dx.doi.org/10.1167/tvst.3.3.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356355PMC
May 2014

Molecular mechanism involved in the maintenance of pluripotent stem cells.

J Stem Cells 2011 ;6(4):213-32

Department of Biological Chemistry, University of California Irvine, Irvine, CA 92697, USA.

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June 2013

Maintenance of human embryonic stem cells by sphingosine-1-phosphate and platelet-derived growth factor.

Methods Mol Biol 2012 ;874:167-75

Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.

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http://link.springer.com/10.1007/978-1-61779-800-9_13
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http://dx.doi.org/10.1007/978-1-61779-800-9_13DOI Listing
November 2012

Biological effects of lysophosphatidic acid in the nervous system.

Int Rev Cell Mol Biol 2012 ;296:273-322

Department of Ophthalmology, The University of Melbourne, East Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1016/B978-0-12-394307-1.00005-9DOI Listing
October 2012

In vivo tissue engineering chamber supports human induced pluripotent stem cell survival and rapid differentiation.

Biochem Biophys Res Commun 2012 May 27;422(1):75-9. Epub 2012 Apr 27.

O'Brien Institute and University of Melbourne, Department of Surgery, St. Vincent's Hospital, Fitzroy, Victoria 3065, Australia.

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http://dx.doi.org/10.1016/j.bbrc.2012.04.108DOI Listing
May 2012

Late passage human fibroblasts induced to pluripotency are capable of directed neuronal differentiation.

Cell Transplant 2011 17;20(2):193-203. Epub 2010 Aug 17.

Centre for Reproduction and Development, Monash Institute of Medical Research, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.3727/096368910X514305DOI Listing
August 2011

Modulation of LPA receptor expression in the human brain following neurotrauma.

Cell Mol Neurobiol 2011 May 15;31(4):569-77. Epub 2011 Jan 15.

National Trauma Research Institute, The Alfred Hospital and Department of Medicine, Monash University, Melbourne, VIC, 3004, Australia.

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http://dx.doi.org/10.1007/s10571-011-9650-0DOI Listing
May 2011

G-protein coupled receptors in stem cell self-renewal and differentiation.

Stem Cell Rev Rep 2010 Sep;6(3):351-66

Stem Cell Medicine, O'Brien Institute, Melbourne, Australia.

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http://dx.doi.org/10.1007/s12015-010-9167-9DOI Listing
September 2010

LPA receptor expression in the central nervous system in health and following injury.

Cell Tissue Res 2010 Jul 22;341(1):23-32. Epub 2010 May 22.

Centre for Neuroscience, The University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1007/s00441-010-0977-5DOI Listing
July 2010

Study of gap junctions in human embryonic stem cells.

Methods Mol Biol 2010 ;584:211-28

Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.

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http://dx.doi.org/10.1007/978-1-60761-369-5_12DOI Listing
February 2010

Regulation of stem cell pluripotency and neural differentiation by lysophospholipids.

Neurosignals 2009 30;17(4):242-54. Epub 2009 Sep 30.

Division of Human Immunology, Centre for Cancer Biology, SA Pathology, University of Adelaide, Adelaide, S.A., Australia.

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http://dx.doi.org/10.1159/000231891DOI Listing
January 2010

Small-molecule induction of neural crest-like cells derived from human neural progenitors.

Stem Cells 2009 Dec;27(12):2896-905

Department of Anatomy & Cell Biology,, The University of Melbourne, Parkville, Victoria, Australia 3010.

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http://dx.doi.org/10.1002/stem.208DOI Listing
December 2009

Role of gap junctions in embryonic and somatic stem cells.

Stem Cell Rev 2008 Dec;4(4):283-92

Department of Biological Chemistry, University of California Irvine, Irvine, CA, USA.

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http://dx.doi.org/10.1007/s12015-008-9038-9DOI Listing
December 2008

Lysophosphatidic acid inhibits neuronal differentiation of neural stem/progenitor cells derived from human embryonic stem cells.

Stem Cells 2008 May 28;26(5):1146-54. Epub 2008 Feb 28.

Centre for Neuroscience, University of Melbourne, Parkville 3010, Victoria, Australia.

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http://dx.doi.org/10.1634/stemcells.2007-1118DOI Listing
May 2008

Anti-apoptotic effect of sphingosine-1-phosphate and platelet-derived growth factor in human embryonic stem cells.

Stem Cells Dev 2007 Dec;16(6):989-1001

Monash Institute of Medical Research, Monash University, Clayton, Victoria 3168, Australia.

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http://dx.doi.org/10.1089/scd.2007.0057DOI Listing
December 2007

Stem cell regulation by lysophospholipids.

Prostaglandins Other Lipid Mediat 2007 Nov 5;84(3-4):83-97. Epub 2007 Sep 5.

Centre for Neuroscience and Department of Pharmacology, The University of Melbourne, Parkville, Victoria 3010, Australia.

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http://dx.doi.org/10.1016/j.prostaglandins.2007.08.004DOI Listing
November 2007

Gap junctions modulate apoptosis and colony growth of human embryonic stem cells maintained in a serum-free system.

Biochem Biophys Res Commun 2006 May 17;344(1):181-8. Epub 2006 Apr 17.

Monash Institute of Medical Research, Laboratory of Embryonic Stem Cell Biology, Australian Stem Cell Centre, Building 75, STRIP Monash University, Wellington Road, Clayton, Vic. 3800, Australia.

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http://dx.doi.org/10.1016/j.bbrc.2006.03.127DOI Listing
May 2006

Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells.

Stem Cells 2005 Nov-Dec;23(10):1541-8. Epub 2005 Aug 4.

Monash Institute of Medical Research, Laboratory of Embryonic Stem Cell Biology, Australian Stem Cell Centre, STRIP Monash University, Clayton VIC 3800, Australia.

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http://dx.doi.org/10.1634/stemcells.2004-0338DOI Listing
March 2006

S1P inhibits gap junctions in astrocytes: involvement of G and Rho GTPase/ROCK.

Eur J Neurosci 2006 Mar;23(6):1453-64

INSERM U587, Collège de France, 11, Place Marcelin Berthelot, 75005 Paris, France.

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http://dx.doi.org/10.1111/j.1460-9568.2006.04671.xDOI Listing
March 2006

A role for neurotrophins in embryonic stem cell growth.

Dev Cell 2006 Feb;10(2):158-9

Monash Immunology and Stem Cell Laboratories, Monash University, Building 75, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1016/j.devcel.2006.01.007DOI Listing
February 2006

Presence of functional gap junctions in human embryonic stem cells.

Stem Cells 2004 ;22(6):883-9

Monash Institute of Reproduction and Development, Monash University, 246 Clayton Road, Clayton, VIC 3168, Australia.

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http://dx.doi.org/10.1634/stemcells.22-6-883DOI Listing
April 2005