Alice M Arnold

Alice M Arnold

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Alice M Arnold

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A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 Aug 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

Trajectories of Nonagenarian Health: Sex, Age, and Period Effects.

Am J Epidemiol 2019 Feb;188(2):382-388

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

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https://academic.oup.com/aje/advance-article/doi/10.1093/aje
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http://dx.doi.org/10.1093/aje/kwy241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357807PMC
February 2019

Long-Term Cognitive Decline After Newly Diagnosed Heart Failure: Longitudinal Analysis in the CHS (Cardiovascular Health Study).

Circ Heart Fail 2018 03;11(3):e004476

From the Department of Statistics (C.A.H., N.J.B.) and Department of Public Health (E.L.T.), Brigham Young University, Provo, UT; Department of Internal Medicine, Yale School of Medicine, New Haven, CT (S.I.C.); Department of Medicine (J.A.D.) and Department of Population Health (J.A.D.), New York University Langone Medical Center; Cardiovascular Health Research Unit (S.R.H., B.M.P., C.M.S.), Department of Neurology (W.T.L.), Department of Epidemiology (W.T.L., S.R.H., B.M.P., S.D.), Department of Medicine (B.M.P., C.M.S.), Department of Health Services (B.M.P.), Department of Biostatistics (A.M.A.), and Department of Psychiatry and Behavioral Sciences (S.M.T.), University of Washington, Seattle; Kaiser Permanente Washington Health Research Institute, Seattle (S.R.H., B.M.P., S.D.); Department of Medicine, Rutgers New Jersey Medical School, Newark (J.M.G.); Geriatric Research, Education, and Clinical Center, Seattle VA Medical Center, WA (S.M.T.); Department of Medicine, Duke University School of Medicine, Durham, NC (M.G.N.); Department of Neurology, Johns Hopkins University, Baltimore, MD (R.F.G.); and Department of Epidemiology (A.B.N.), Department of Medicine (A.B.N.), and Clinical and Translational Science Institute (A.B.N.), University of Pittsburgh, PA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.117.004476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072263PMC
March 2018

Age, Race, and Gender Factors in Incident Disability.

J Gerontol A Biol Sci Med Sci 2018 01;73(2):194-197

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1093/gerona/glx194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861898PMC
January 2018

Mortality After Bereavement: The Role of Cardiovascular Disease and Depression.

Psychosom Med 2016 Jul-Aug;78(6):697-703

From the Departments of Psychiatry (Stahl, Schulz) and Biostatistics (Chen, Anderson) and University Center for Social and Urban Research (Stahl, Schulz), University of Pittsburgh, Pittsburgh, Pennsylvania; and Department of Biostatistics (Arnold), University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1097/PSY.0000000000000317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927386PMC
July 2017

Factors Associated With Ischemic Stroke Survival and Recovery in Older Adults.

Stroke 2017 07 19;48(7):1818-1826. Epub 2017 May 19.

From the School of Biological and Population Health Sciences, Oregon State University, Corvallis (D.T.W., M.C.O.); School of Medicine, Oregon Health and Science University, Portland (D.T.W.); Department of Neurology (W.T.L.), and Department of Biostatistics (A.M.A.), University of Washington, Seattle; Department of Oncology, John Hopkins University, Baltimore, MD (R.V.); Department of Public Health Sciences, University of Miami, Coral Gables, FL (A.Z.A.H.); Department of Pathology and Laboratory Medicine, and Department of Medicine, University of Vermont, Burlington (M.C.); and Department of Epidemiology, University of Pittsburgh, PA (A.B.N.).

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http://dx.doi.org/10.1161/STROKEAHA.117.016726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553701PMC
July 2017

Health and Functional Status of Adults Aged 90 Years in the United States.

JAMA Intern Med 2017 05;177(5):732-734

Graduate School of Public Health, University of Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1001/jamainternmed.2017.0242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639915PMC
May 2017

Meta-analysis of genome-wide association studies of HDL cholesterol response to statins.

J Med Genet 2016 12 1;53(12):835-845. Epub 2016 Sep 1.

Department of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, California, USA.

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http://dx.doi.org/10.1136/jmedgenet-2016-103966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309131PMC
December 2016

Can a Healthy Lifestyle Compress the Disabled Period in Older Adults?

J Am Geriatr Soc 2016 10 7;64(10):1952-1961. Epub 2016 Sep 7.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073015PMC
http://dx.doi.org/10.1111/jgs.14314DOI Listing
October 2016

Trajectories of function and biomarkers with age: the CHS All Stars Study.

Int J Epidemiol 2016 08 6;45(4):1135-1145. Epub 2016 Jun 6.

Collaborative Health Studies Coordinating Center, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1093/ije/dyw092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841627PMC
August 2016

Lipoprotein-Associated Phospholipase A2 and Incident Peripheral Arterial Disease in Older Adults: The Cardiovascular Health Study.

Arterioscler Thromb Vasc Biol 2016 Apr 4;36(4):750-6. Epub 2016 Feb 4.

From the Division of Cardiology, University of Southern California Keck School of Medicine, Los Angeles (P.K.G.); Department of Biostatistics, University of Washington, Seattle (A.M.A., K.D.H.S.); Glaxo Smith Kline, Collegeville, PA (C.K.); Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington (N.S.J., M.C.); Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA (K.J.M.); Department of Family and Preventive Medicine, University of California in San Diego School of Medicine, La Jolla (M.H.C.); Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC (C.D.F.); Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA (A.B.N.); and Department of Medicine, Cardiovascular Research Institute, University of Vermont College of Medicine, Burlington (M.C.).

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http://cdn.intechopen.com/pdfs-wm/49149.pdf
Web Search
http://atvb.ahajournals.org/lookup/doi/10.1161/ATVBAHA.115.3
Publisher Site
http://dx.doi.org/10.1161/ATVBAHA.115.306647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808367PMC
April 2016

Study of Cardiovascular Health Outcomes in the Era of Claims Data: The Cardiovascular Health Study.

Circulation 2016 Jan 4;133(2):156-64. Epub 2015 Nov 4.

From Cardiovascular Health Research Unit, Department of Medicine (B.M.P.), Department of Epidemiology (B.M.P., J.A.D., S.R.H.), Department of Health Services (B.M.P.), Department of Biostatistics (A.M.A., B.M.), Department of Global Health (A.L.F.), Department of Family Medicine (A.L.F.), and Department of Neurology (W.T.L.), University of Washington, Seattle; Group Health Research Institute, Group Health Cooperative, Seattle, WA (B.M.P., S.R.H.); Department of Medicine, Duke University, Durham, NC (L.H.C.); Department of Epidemiology, University of Pittsburgh, PA (D.I., L.H.K.); and Department of Medicine, University of Maryland, Baltimore (J.S.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.018610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814341PMC
January 2016

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Authors:
Felix R Day Katherine S Ruth Deborah J Thompson Kathryn L Lunetta Natalia Pervjakova Daniel I Chasman Lisette Stolk Hilary K Finucane Patrick Sulem Brendan Bulik-Sullivan Tõnu Esko Andrew D Johnson Cathy E Elks Nora Franceschini Chunyan He Elisabeth Altmaier Jennifer A Brody Lude L Franke Jennifer E Huffman Margaux F Keller Patrick F McArdle Teresa Nutile Eleonora Porcu Antonietta Robino Lynda M Rose Ursula M Schick Jennifer A Smith Alexander Teumer Michela Traglia Dragana Vuckovic Jie Yao Wei Zhao Eva Albrecht Najaf Amin Tanguy Corre Jouke-Jan Hottenga Massimo Mangino Albert V Smith Toshiko Tanaka Goncalo Abecasis Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Volker Arndt Alice M Arnold Caterina Barbieri Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Leslie Bernstein Suzette J Bielinski Carl Blomqvist Eric Boerwinkle Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Anne-Lise Borresen-Dale Thibaud S Boutin Hiltrud Brauch Hermann Brenner Thomas Brüning Barbara Burwinkel Archie Campbell Harry Campbell Stephen J Chanock J Ross Chapman Yii-Der Ida Chen Georgia Chenevix-Trench Fergus J Couch Andrea D Coviello Angela Cox Kamila Czene Hatef Darabi Immaculata De Vivo Ellen W Demerath Joe Dennis Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Alison M Dunning John D Eicher Peter A Fasching Jessica D Faul Jonine Figueroa Dieter Flesch-Janys Ilaria Gandin Melissa E Garcia Montserrat García-Closas Graham G Giles Giorgia G Girotto Mark S Goldberg Anna González-Neira Mark O Goodarzi Megan L Grove Daniel F Gudbjartsson Pascal Guénel Xiuqing Guo Christopher A Haiman Per Hall Ute Hamann Brian E Henderson Lynne J Hocking Albert Hofman Georg Homuth Maartje J Hooning John L Hopper Frank B Hu Jinyan Huang Keith Humphreys David J Hunter Anna Jakubowska Samuel E Jones Maria Kabisch David Karasik Julia A Knight Ivana Kolcic Charles Kooperberg Veli-Matti Kosma Jennifer Kriebel Vessela Kristensen Diether Lambrechts Claudia Langenberg Jingmei Li Xin Li Sara Lindström Yongmei Liu Jian'an Luan Jan Lubinski Reedik Mägi Arto Mannermaa Judith Manz Sara Margolin Jonathan Marten Nicholas G Martin Corrado Masciullo Alfons Meindl Kyriaki Michailidou Evelin Mihailov Lili Milani Roger L Milne Martina Müller-Nurasyid Michael Nalls Ben M Neale Heli Nevanlinna Patrick Neven Anne B Newman Børge G Nordestgaard Janet E Olson Sandosh Padmanabhan Paolo Peterlongo Ulrike Peters Astrid Petersmann Julian Peto Paul D P Pharoah Nicola N Pirastu Ailith Pirie Giorgio Pistis Ozren Polasek David Porteous Bruce M Psaty Katri Pylkäs Paolo Radice Leslie J Raffel Fernando Rivadeneira Igor Rudan Anja Rudolph Daniela Ruggiero Cinzia F Sala Serena Sanna Elinor J Sawyer David Schlessinger Marjanka K Schmidt Frank Schmidt Rita K Schmutzler Minouk J Schoemaker Robert A Scott Caroline M Seynaeve Jacques Simard Rossella Sorice Melissa C Southey Doris Stöckl Konstantin Strauch Anthony Swerdlow Kent D Taylor Unnur Thorsteinsdottir Amanda E Toland Ian Tomlinson Thérèse Truong Laufey Tryggvadottir Stephen T Turner Diego Vozzi Qin Wang Melissa Wellons Gonneke Willemsen James F Wilson Robert Winqvist Bruce B H R Wolffenbuttel Alan F Wright Drakoulis Yannoukakos Tatijana Zemunik Wei Zheng Marek Zygmunt Sven Bergmann Dorret I Boomsma Julie E Buring Luigi Ferrucci Grant W Montgomery Vilmundur Gudnason Tim D Spector Cornelia M van Duijn Behrooz Z Alizadeh Marina Ciullo Laura Crisponi Douglas F Easton Paolo P Gasparini Christian Gieger Tamara B Harris Caroline Hayward Sharon L R Kardia Peter Kraft Barbara McKnight Andres Metspalu Alanna C Morrison Alex P Reiner Paul M Ridker Jerome I Rotter Daniela Toniolo André G Uitterlinden Sheila Ulivi Henry Völzke Nicholas J Wareham David R Weir Laura M Yerges-Armstrong Alkes L Price Kari Stefansson Jenny A Visser Ken K Ong Jenny Chang-Claude Joanne M Murabito John R B Perry Anna Murray

Nat Genet 2015 Nov 28;47(11):1294-1303. Epub 2015 Sep 28.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.

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http://dx.doi.org/10.1038/ng.3412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661791PMC
November 2015

Years of able life in older persons--the role of cardiovascular imaging and biomarkers: the Cardiovascular Health Study.

J Am Heart Assoc 2015 Apr 23;4(4). Epub 2015 Apr 23.

Department of Internal Medicine, University of Iowa, Iowa City, IA (R.B.W.) Carver College of Medicine and the College of Public Health, University of Iowa, Iowa City, IA (L.I.A., R.B.W.).

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http://dx.doi.org/10.1161/JAHA.114.001745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579951PMC
April 2015

Multisystem physiologic impairments and changes in gait speed of older adults.

J Gerontol A Biol Sci Med Sci 2015 Mar 7;70(3):319-24. Epub 2014 Nov 7.

Department of Epidemiology, School of Public Health, University of Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1093/gerona/glu176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351395PMC
March 2015

Thyroid function in the euthyroid range and adverse outcomes in older adults.

J Clin Endocrinol Metab 2015 Mar 16;100(3):1088-96. Epub 2014 Dec 16.

Division of Endocrinology, Diabetes and Metabolism (A.R.C., K.W.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104; Department of Biostatistics (A.M.A.), University of Washington, Seattle, Washington ; Department of Mental Health (M.C.), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205; Division of General Medicine (J.R.), University of California, Davis, Sacramento, California 95817; Cardiovascular Health Research Unit (B.M.P.), Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington 98101; and Group Health Research Institute (B.M.P.), Group Health Cooperative, Seattle, Washington 98101.

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http://dx.doi.org/10.1210/jc.2014-3586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333030PMC
March 2015

Testosterone and dihydrotestosterone and incident ischaemic stroke in men in the Cardiovascular Health Study.

Clin Endocrinol (Oxf) 2014 Nov 5;81(5):746-53. Epub 2014 May 5.

VA Puget Sound Health Care System, Seattle, WA, USA; Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1111/cen.12452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169352PMC
November 2014

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins.

Authors:
Iris Postmus Stella Trompet Harshal A Deshmukh Michael R Barnes Xiaohui Li Helen R Warren Daniel I Chasman Kaixin Zhou Benoit J Arsenault Louise A Donnelly Kerri L Wiggins Christy L Avery Paula Griffin QiPing Feng Kent D Taylor Guo Li Daniel S Evans Albert V Smith Catherine E de Keyser Andrew D Johnson Anton J M de Craen David J Stott Brendan M Buckley Ian Ford Rudi G J Westendorp P Eline Slagboom Naveed Sattar Patricia B Munroe Peter Sever Neil Poulter Alice Stanton Denis C Shields Eoin O'Brien Sue Shaw-Hawkins Y-D Ida Chen Deborah A Nickerson Joshua D Smith Marie Pierre Dubé S Matthijs Boekholdt G Kees Hovingh John J P Kastelein Paul M McKeigue John Betteridge Andrew Neil Paul N Durrington Alex Doney Fiona Carr Andrew Morris Mark I McCarthy Leif Groop Emma Ahlqvist Joshua C Bis Kenneth Rice Nicholas L Smith Thomas Lumley Eric A Whitsel Til Stürmer Eric Boerwinkle Julius S Ngwa Christopher J O'Donnell Ramachandran S Vasan Wei-Qi Wei Russell A Wilke Ching-Ti Liu Fangui Sun Xiuqing Guo Susan R Heckbert Wendy Post Nona Sotoodehnia Alice M Arnold Jeanette M Stafford Jingzhong Ding David M Herrington Stephen B Kritchevsky Gudny Eiriksdottir Leonore J Launer Tamara B Harris Audrey Y Chu Franco Giulianini Jean G MacFadyen Bryan J Barratt Fredrik Nyberg Bruno H Stricker André G Uitterlinden Albert Hofman Fernando Rivadeneira Valur Emilsson Oscar H Franco Paul M Ridker Vilmundur Gudnason Yongmei Liu Joshua C Denny Christie M Ballantyne Jerome I Rotter L Adrienne Cupples Bruce M Psaty Colin N A Palmer Jean-Claude Tardif Helen M Colhoun Graham Hitman Ronald M Krauss J Wouter Jukema Mark J Caulfield

Nat Commun 2014 Oct 28;5:5068. Epub 2014 Oct 28.

1] NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK [2] Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine, Queen Mary University of London, London EC1M6BQ, UK.

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http://dx.doi.org/10.1038/ncomms6068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220464PMC
October 2014

Subclinical vascular disease burden and longer survival.

J Am Geriatr Soc 2014 Sep;62(9):1692-8

School of Biological and Population Health Sciences, Oregon State University, Corvallis, Oregon.

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http://dx.doi.org/10.1111/jgs.13018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176817PMC
September 2014

Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults: the cardiovascular health study.

J Clin Endocrinol Metab 2014 Aug 30;99(8):2657-64. Epub 2014 May 30.

Division of Endocrinology, Diabetes, and Metabolism (M.C.G., A.R.C.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104; Department of Biostatistics (A.M.A.), University of Washington, Seattle, Washington 98155; Division of Endocrinology, Gerontology, and Metabolism (J.S.L.), Stanford University School of Medicine and Veterans Affairs Palo Alto Health Care System (J.S.L.), Palo Alto, California 94305; and Division of General Medicine (J.R.), University of California, Davis, Sacramento, California 95817.

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http://dx.doi.org/10.1210/jc.2014-1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121038PMC
August 2014

Advanced glycation/glycoxidation endproduct carboxymethyl-lysine and incidence of coronary heart disease and stroke in older adults.

Atherosclerosis 2014 Jul 30;235(1):116-21. Epub 2014 Apr 30.

Division of Geriatrics and Clinical Gerontology, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2014.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169874PMC
July 2014

Testosterone, dihydrotestosterone, and incident cardiovascular disease and mortality in the cardiovascular health study.

J Clin Endocrinol Metab 2014 Jun 14;99(6):2061-8. Epub 2014 Mar 14.

VA Puget Sound Health Care System (M.M.S., N.L.S., A.M.M.), VA Epidemiologic Research and Information Center (N.L.S.), and Geriatric Research, Education, and Clinical Care (A.M.M.), Seattle, Washington 98108; Departments of Psychiatry and Behavioral Sciences (M.M.S.), Biostatistics (M.L.B., A.M.A.), Epidemiology (N.L.S., W.T.L.), Neurology (W.T.L.), and Medicine (A.M.M.), Division of Gerontology and Geriatric Medicine, University of Washington, Seattle, Washington 98195; Department of Medicine and Department of Epidemiology and Population Health (J.R.K.), Albert Einstein College of Medicine, Bronx, New York 10461; Department of Internal Medicine (C.H.H.), Geriatric Medicine, University of California-Davis, Davis, California 95616; and Department of Internal Medicine (A.R.C.), Endocrinology Division, University of Pennsylvania, Philadelphia, Pennsylvania 19104.

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http://dx.doi.org/10.1210/jc.2013-3576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4037728PMC
June 2014

Infection hospitalization increases risk of dementia in the elderly.

Crit Care Med 2014 May;42(5):1037-46

1Department of Acute and Tertiary Care, School of Nursing, University of Pittsburgh, Pittsburgh, PA. 2Department of Neurology, University of Pittsburgh, Pittsburgh, PA. 3Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. 4National Center for Complementary and Alternative Medicine (NCCAM), National Institutes of Health, Bethesda, MD. 5The Clinical Research, Investigation, and Systems Modeling of Acute Illness Center, University of Pittsburgh, Pittsburgh, PA. 6Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA. 7Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA. 8Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA. 9Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA. 10Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC. 11Department of Biostatistics, University of Washington, Seattle, WA. 12School of Medicine, University of Virginia, Charlottesville, VA.

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http://dx.doi.org/10.1097/CCM.0000000000000123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071960PMC
May 2014

Subclinical hypothyroidism, weight change, and body composition in the elderly: the Cardiovascular Health Study.

J Clin Endocrinol Metab 2014 Apr 16;99(4):1220-6. Epub 2014 Jan 16.

Division of Endocrinology, Diabetes, and Metabolism (M.C.G., A.R.C.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104; Department of Biostatistics (A.M.A.), University of Washington, Seattle, Washington 98155; Division of Endocrinology, Gerontology, and Metabolism (J.S.L.), Stanford University School of Medicine and Veterans Administration Palo Alto Health Care System, Palo Alto, California 94305; and Departments of Pathology and Biochemistry (R.P.T.), University of Vermont, Burlington, Vermont 05405.

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http://dx.doi.org/10.1210/jc.2013-3591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973778PMC
April 2014

Do changes in circulating biomarkers track with each other and with functional changes in older adults?

J Gerontol A Biol Sci Med Sci 2014 Feb 28;69(2):174-81. Epub 2013 Jun 28.

Bellefield Professional Building 4th Floor, 130 North Bellefield Avenue, Pittsburgh, PA 15213.

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http://dx.doi.org/10.1093/gerona/glt088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038245PMC
February 2014

Relations of plasma total and high-molecular-weight adiponectin to new-onset heart failure in adults ≥65 years of age (from the Cardiovascular Health study).

Am J Cardiol 2014 Jan 3;113(2):328-34. Epub 2013 Oct 3.

Department of Medicine, Albert Einstein College of Medicine, Bronx, New York; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2013.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968249PMC
January 2014

Atrial fibrillation and cognitive decline: a longitudinal cohort study.

Neurology 2013 Jul 5;81(2):119-25. Epub 2013 Jun 5.

Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1212/WNL.0b013e31829a33d1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770176PMC
July 2013

Results differ by applying distinctive multiple imputation approaches on the longitudinal cardiovascular health study data.

Exp Aging Res 2013 ;39(1):27-43

Section of Geriatrics, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1080/0361073X.2013.741968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547387PMC
June 2013

Persistent subclinical hypothyroidism and cardiovascular risk in the elderly: the cardiovascular health study.

J Clin Endocrinol Metab 2013 Feb 16;98(2):533-40. Epub 2012 Nov 16.

Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, 12-136 Translational Research Center, 3400 Civic Center Boulevard, Philadelphia, Pennsylvania 19104-5160, USA.

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http://dx.doi.org/10.1210/jc.2012-2180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565111PMC
February 2013

Hemoglobin decline, function, and mortality in the elderly: the cardiovascular health study.

Am J Hematol 2013 Jan 9;88(1):5-9. Epub 2012 Oct 9.

Departments of Medicine and Pathology, University of Vermont, Burlington, Vermont College of Medicine, USA.

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http://dx.doi.org/10.1002/ajh.23336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860593PMC
January 2013

Longitudinal changes in thyroid function in the oldest old and survival: the cardiovascular health study all-stars study.

J Clin Endocrinol Metab 2012 Nov 9;97(11):3944-50. Epub 2012 Aug 9.

Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, 12-136 Translational Research Center, 3400 Civic Center Boulevard, Philadelphia, Pennsylvania 19104-5160, USA.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
Publisher Site
http://dx.doi.org/10.1210/jc.2012-2481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485600PMC
November 2012

Long-term assessment of inflammation and healthy aging in late life: the Cardiovascular Health Study All Stars.

J Gerontol A Biol Sci Med Sci 2012 Sep 24;67(9):970-6. Epub 2012 Feb 24.

Department of Pathology, University of Vermont College of Medicine, 208 South Park Drive, Colchester, VT 05446, USA.

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http://dx.doi.org/10.1093/gerona/glr261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436091PMC
September 2012

The natural history of subclinical hypothyroidism in the elderly: the cardiovascular health study.

J Clin Endocrinol Metab 2012 Jun 21;97(6):1962-9. Epub 2012 Mar 21.

Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-5160, USA.

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http://dx.doi.org/10.1210/jc.2011-3047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3387427PMC
June 2012

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

Authors:
Lisette Stolk John R B Perry Daniel I Chasman Chunyan He Massimo Mangino Patrick Sulem Maja Barbalic Linda Broer Enda M Byrne Florian Ernst Tõnu Esko Nora Franceschini Daniel F Gudbjartsson Jouke-Jan Hottenga Peter Kraft Patrick F McArdle Eleonora Porcu So-Youn Shin Albert V Smith Sophie van Wingerden Guangju Zhai Wei V Zhuang Eva Albrecht Behrooz Z Alizadeh Thor Aspelund Stefania Bandinelli Lovorka Barac Lauc Jacques S Beckmann Mladen Boban Eric Boerwinkle Frank J Broekmans Andrea Burri Harry Campbell Stephen J Chanock Constance Chen Marilyn C Cornelis Tanguy Corre Andrea D Coviello Pio d'Adamo Gail Davies Ulf de Faire Eco J C de Geus Ian J Deary George V Z Dedoussis Panagiotis Deloukas Shah Ebrahim Gudny Eiriksdottir Valur Emilsson Johan G Eriksson Bart C J M Fauser Liana Ferreli Luigi Ferrucci Krista Fischer Aaron R Folsom Melissa E Garcia Paolo Gasparini Christian Gieger Nicole Glazer Diederick E Grobbee Per Hall Toomas Haller Susan E Hankinson Merli Hass Caroline Hayward Andrew C Heath Albert Hofman Erik Ingelsson A Cecile J W Janssens Andrew D Johnson David Karasik Sharon L R Kardia Jules Keyzer Douglas P Kiel Ivana Kolcic Zoltán Kutalik Jari Lahti Sandra Lai Triin Laisk Joop S E Laven Debbie A Lawlor Jianjun Liu Lorna M Lopez Yvonne V Louwers Patrik K E Magnusson Mara Marongiu Nicholas G Martin Irena Martinovic Klaric Corrado Masciullo Barbara McKnight Sarah E Medland David Melzer Vincent Mooser Pau Navarro Anne B Newman Dale R Nyholt N Charlotte Onland-Moret Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Petra H M Peeters Giorgio Pistis Andrew S Plump Ozren Polasek Victor J M Pop Bruce M Psaty Katri Räikkönen Emil Rehnberg Jerome I Rotter Igor Rudan Cinzia Sala Andres Salumets Angelo Scuteri Andrew Singleton Jennifer A Smith Harold Snieder Nicole Soranzo Simon N Stacey John M Starr Maria G Stathopoulou Kathleen Stirrups Ronald P Stolk Unnur Styrkarsdottir Yan V Sun Albert Tenesa Barbara Thorand Daniela Toniolo Laufey Tryggvadottir Kim Tsui Sheila Ulivi Rob M van Dam Yvonne T van der Schouw Carla H van Gils Peter van Nierop Jacqueline M Vink Peter M Visscher Marlies Voorhuis Gérard Waeber Henri Wallaschofski H Erich Wichmann Elisabeth Widen Colette J M Wijnands-van Gent Gonneke Willemsen James F Wilson Bruce H R Wolffenbuttel Alan F Wright Laura M Yerges-Armstrong Tatijana Zemunik Lina Zgaga M Carola Zillikens Marek Zygmunt Alice M Arnold Dorret I Boomsma Julie E Buring Laura Crisponi Ellen W Demerath Vilmundur Gudnason Tamara B Harris Frank B Hu David J Hunter Lenore J Launer Andres Metspalu Grant W Montgomery Ben A Oostra Paul M Ridker Serena Sanna David Schlessinger Tim D Spector Kari Stefansson Elizabeth A Streeten Unnur Thorsteinsdottir Manuela Uda André G Uitterlinden Cornelia M van Duijn Henry Völzke Anna Murray Joanne M Murabito Jenny A Visser Kathryn L Lunetta

Nat Genet 2012 Jan 22;44(3):260-8. Epub 2012 Jan 22.

Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288642PMC
January 2012

Progression of magnetic resonance imaging-defined brain vascular disease predicts vascular events in elderly: the Cardiovascular Health Study.

Stroke 2011 Oct 4;42(10):2970-2. Epub 2011 Aug 4.

Department of Neurology, University of Washington, Box 359775, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104-2420, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183167PMC
October 2011

Serum 25-hydroxyvitamin D and physical function in older adults: the Cardiovascular Health Study All Stars.

J Am Geriatr Soc 2011 Oct 21;59(10):1793-801. Epub 2011 Sep 21.

Section on Gerontology and Geriatric Medicine, Department of Internal Medicine, Sticht Center on Aging, Wake Forest School of Medicine, Winston Salem, NC 27157, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228270PMC
October 2011

Subclinical vascular disease burden and risk for death and cardiovascular events in older community dwellers.

J Gerontol A Biol Sci Med Sci 2011 Sep 24;66(9):986-93. Epub 2011 Jun 24.

Pere Virgili Hospital and Institute on Aging, Autonomous University of Barcelona, C Esteve Terrades 30, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202905PMC
September 2011

Predictors of thyroid hormone initiation in older adults: results from the cardiovascular health study.

J Gerontol A Biol Sci Med Sci 2011 Jul 31;66(7):809-14. Epub 2011 May 31.

Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143350PMC
July 2011

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.

Authors:
Tuomas O Kilpeläinen M Carola Zillikens Alena Stančákova Francis M Finucane Janina S Ried Claudia Langenberg Weihua Zhang Jacques S Beckmann Jian'an Luan Liesbeth Vandenput Unnur Styrkarsdottir Yanhua Zhou Albert Vernon Smith Jing-Hua Zhao Najaf Amin Sailaja Vedantam So-Youn Shin Talin Haritunians Mao Fu Mary F Feitosa Meena Kumari Bjarni V Halldorsson Emmi Tikkanen Massimo Mangino Caroline Hayward Ci Song Alice M Arnold Yurii S Aulchenko Ben A Oostra Harry Campbell L Adrienne Cupples Kathryn E Davis Angela Döring Gudny Eiriksdottir Karol Estrada José Manuel Fernández-Real Melissa Garcia Christian Gieger Nicole L Glazer Candace Guiducci Albert Hofman Steve E Humphries Bo Isomaa Leonie C Jacobs Antti Jula David Karasik Magnus K Karlsson Kay-Tee Khaw Lauren J Kim Mika Kivimäki Norman Klopp Brigitte Kühnel Johanna Kuusisto Yongmei Liu Osten Ljunggren Mattias Lorentzon Robert N Luben Barbara McKnight Dan Mellström Braxton D Mitchell Vincent Mooser José Maria Moreno Satu Männistö Jeffery R O'Connell Laura Pascoe Leena Peltonen Belén Peral Markus Perola Bruce M Psaty Veikko Salomaa David B Savage Robert K Semple Tatjana Skaric-Juric Gunnar Sigurdsson Kijoung S Song Timothy D Spector Ann-Christine Syvänen Philippa J Talmud Gudmar Thorleifsson Unnur Thorsteinsdottir André G Uitterlinden Cornelia M van Duijn Antonio Vidal-Puig Sarah H Wild Alan F Wright Deborah J Clegg Eric Schadt James F Wilson Igor Rudan Samuli Ripatti Ingrid B Borecki Alan R Shuldiner Erik Ingelsson John-Olov Jansson Robert C Kaplan Vilmundur Gudnason Tamara B Harris Leif Groop Douglas P Kiel Fernando Rivadeneira Mark Walker Inês Barroso Peter Vollenweider Gérard Waeber John C Chambers Jaspal S Kooner Nicole Soranzo Joel N Hirschhorn Kari Stefansson H-Erich Wichmann Claes Ohlsson Stephen O'Rahilly Nicholas J Wareham Elizabeth K Speliotes Caroline S Fox Markku Laakso Ruth J F Loos

Nat Genet 2011 Jun 26;43(8):753-60. Epub 2011 Jun 26.

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262230PMC
June 2011

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

Authors:
Iris M Heid Anne U Jackson Joshua C Randall Thomas W Winkler Lu Qi Valgerdur Steinthorsdottir Gudmar Thorleifsson M Carola Zillikens Elizabeth K Speliotes Reedik Mägi Tsegaselassie Workalemahu Charles C White Nabila Bouatia-Naji Tamara B Harris Sonja I Berndt Erik Ingelsson Cristen J Willer Michael N Weedon Jian'an Luan Sailaja Vedantam Tõnu Esko Tuomas O Kilpeläinen Zoltán Kutalik Shengxu Li Keri L Monda Anna L Dixon Christopher C Holmes Lee M Kaplan Liming Liang Josine L Min Miriam F Moffatt Cliona Molony George Nicholson Eric E Schadt Krina T Zondervan Mary F Feitosa Teresa Ferreira Hana Lango Allen Robert J Weyant Eleanor Wheeler Andrew R Wood Karol Estrada Michael E Goddard Guillaume Lettre Massimo Mangino Dale R Nyholt Shaun Purcell Albert Vernon Smith Peter M Visscher Jian Yang Steven A McCarroll James Nemesh Benjamin F Voight Devin Absher Najaf Amin Thor Aspelund Lachlan Coin Nicole L Glazer Caroline Hayward Nancy L Heard-Costa Jouke-Jan Hottenga Asa Johansson Toby Johnson Marika Kaakinen Karen Kapur Shamika Ketkar Joshua W Knowles Peter Kraft Aldi T Kraja Claudia Lamina Michael F Leitzmann Barbara McKnight Andrew P Morris Ken K Ong John R B Perry Marjolein J Peters Ozren Polasek Inga Prokopenko Nigel W Rayner Samuli Ripatti Fernando Rivadeneira Neil R Robertson Serena Sanna Ulla Sovio Ida Surakka Alexander Teumer Sophie van Wingerden Veronique Vitart Jing Hua Zhao Christine Cavalcanti-Proença Peter S Chines Eva Fisher Jennifer R Kulzer Cecile Lecoeur Narisu Narisu Camilla Sandholt Laura J Scott Kaisa Silander Klaus Stark Mari-Liis Tammesoo Tanya M Teslovich Nicholas John Timpson Richard M Watanabe Ryan Welch Daniel I Chasman Matthew N Cooper John-Olov Jansson Johannes Kettunen Robert W Lawrence Niina Pellikka Markus Perola Liesbeth Vandenput Helene Alavere Peter Almgren Larry D Atwood Amanda J Bennett Reiner Biffar Lori L Bonnycastle Stefan R Bornstein Thomas A Buchanan Harry Campbell Ian N M Day Mariano Dei Marcus Dörr Paul Elliott Michael R Erdos Johan G Eriksson Nelson B Freimer Mao Fu Stefan Gaget Eco J C Geus Anette P Gjesing Harald Grallert Jürgen Grässler Christopher J Groves Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Aki S Havulinna Karl-Heinz Herzig Andrew A Hicks Jennie Hui Wilmar Igl Pekka Jousilahti Antti Jula Eero Kajantie Leena Kinnunen Ivana Kolcic Seppo Koskinen Peter Kovacs Heyo K Kroemer Vjekoslav Krzelj Johanna Kuusisto Kirsti Kvaloy Jaana Laitinen Olivier Lantieri G Mark Lathrop Marja-Liisa Lokki Robert N Luben Barbara Ludwig Wendy L McArdle Anne McCarthy Mario A Morken Mari Nelis Matt J Neville Guillaume Paré Alex N Parker John F Peden Irene Pichler Kirsi H Pietiläinen Carl G P Platou Anneli Pouta Martin Ridderstråle Nilesh J Samani Jouko Saramies Juha Sinisalo Jan H Smit Rona J Strawbridge Heather M Stringham Amy J Swift Maris Teder-Laving Brian Thomson Gianluca Usala Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Claudia B Volpato Henri Wallaschofski G Bragi Walters Elisabeth Widen Sarah H Wild Gonneke Willemsen Daniel R Witte Lina Zgaga Paavo Zitting John P Beilby Alan L James Mika Kähönen Terho Lehtimäki Markku S Nieminen Claes Ohlsson Lyle J Palmer Olli Raitakari Paul M Ridker Michael Stumvoll Anke Tönjes Jorma Viikari Beverley Balkau Yoav Ben-Shlomo Richard N Bergman Heiner Boeing George Davey Smith Shah Ebrahim Philippe Froguel Torben Hansen Christian Hengstenberg Kristian Hveem Bo Isomaa Torben Jørgensen Fredrik Karpe Kay-Tee Khaw Markku Laakso Debbie A Lawlor Michel Marre Thomas Meitinger Andres Metspalu Kristian Midthjell Oluf Pedersen Veikko Salomaa Peter E H Schwarz Tiinamaija Tuomi Jaakko Tuomilehto Timo T Valle Nicholas J Wareham Alice M Arnold Jacques S Beckmann Sven Bergmann Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Francis S Collins Gudny Eiriksdottir Vilmundur Gudnason Ulf Gyllensten Anders Hamsten Andrew T Hattersley Albert Hofman Frank B Hu Thomas Illig Carlos Iribarren Marjo-Riitta Jarvelin W H Linda Kao Jaakko Kaprio Lenore J Launer Patricia B Munroe Ben Oostra Brenda W Penninx Peter P Pramstaller Bruce M Psaty Thomas Quertermous Aila Rissanen Igor Rudan Alan R Shuldiner Nicole Soranzo Timothy D Spector Ann-Christine Syvanen Manuela Uda André Uitterlinden Henry Völzke Peter Vollenweider James F Wilson Jacqueline C Witteman Alan F Wright Gonçalo R Abecasis Michael Boehnke Ingrid B Borecki Panos Deloukas Timothy M Frayling Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Kari E North Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Joel N Hirschhorn Themistocles L Assimes H-Erich Wichmann Unnur Thorsteinsdottir Cornelia M van Duijn Kari Stefansson L Adrienne Cupples Ruth J F Loos Inês Barroso Mark I McCarthy Caroline S Fox Karen L Mohlke Cecilia M Lindgren

Nat Genet 2010 Nov 10;42(11):949-60. Epub 2010 Oct 10.

Regensburg University Medical Center, Department of Epidemiology and Preventive Medicine, Regensburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000924PMC
November 2010

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Authors:
Elizabeth K Speliotes Cristen J Willer Sonja I Berndt Keri L Monda Gudmar Thorleifsson Anne U Jackson Hana Lango Allen Cecilia M Lindgren Jian'an Luan Reedik Mägi Joshua C Randall Sailaja Vedantam Thomas W Winkler Lu Qi Tsegaselassie Workalemahu Iris M Heid Valgerdur Steinthorsdottir Heather M Stringham Michael N Weedon Eleanor Wheeler Andrew R Wood Teresa Ferreira Robert J Weyant Ayellet V Segrè Karol Estrada Liming Liang James Nemesh Ju-Hyun Park Stefan Gustafsson Tuomas O Kilpeläinen Jian Yang Nabila Bouatia-Naji Tõnu Esko Mary F Feitosa Zoltán Kutalik Massimo Mangino Soumya Raychaudhuri Andre Scherag Albert Vernon Smith Ryan Welch Jing Hua Zhao Katja K Aben Devin M Absher Najaf Amin Anna L Dixon Eva Fisher Nicole L Glazer Michael E Goddard Nancy L Heard-Costa Volker Hoesel Jouke-Jan Hottenga Asa Johansson Toby Johnson Shamika Ketkar Claudia Lamina Shengxu Li Miriam F Moffatt Richard H Myers Narisu Narisu John R B Perry Marjolein J Peters Michael Preuss Samuli Ripatti Fernando Rivadeneira Camilla Sandholt Laura J Scott Nicholas J Timpson Jonathan P Tyrer Sophie van Wingerden Richard M Watanabe Charles C White Fredrik Wiklund Christina Barlassina Daniel I Chasman Matthew N Cooper John-Olov Jansson Robert W Lawrence Niina Pellikka Inga Prokopenko Jianxin Shi Elisabeth Thiering Helene Alavere Maria T S Alibrandi Peter Almgren Alice M Arnold Thor Aspelund Larry D Atwood Beverley Balkau Anthony J Balmforth Amanda J Bennett Yoav Ben-Shlomo Richard N Bergman Sven Bergmann Heike Biebermann Alexandra I F Blakemore Tanja Boes Lori L Bonnycastle Stefan R Bornstein Morris J Brown Thomas A Buchanan Fabio Busonero Harry Campbell Francesco P Cappuccio Christine Cavalcanti-Proença Yii-Der Ida Chen Chih-Mei Chen Peter S Chines Robert Clarke Lachlan Coin John Connell Ian N M Day Martin den Heijer Jubao Duan Shah Ebrahim Paul Elliott Roberto Elosua Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Maurizio F Facheris Stephan B Felix Pamela Fischer-Posovszky Aaron R Folsom Nele Friedrich Nelson B Freimer Mao Fu Stefan Gaget Pablo V Gejman Eco J C Geus Christian Gieger Anette P Gjesing Anuj Goel Philippe Goyette Harald Grallert Jürgen Grässler Danielle M Greenawalt Christopher J Groves Vilmundur Gudnason Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Alistair S Hall Aki S Havulinna Caroline Hayward Andrew C Heath Christian Hengstenberg Andrew A Hicks Anke Hinney Albert Hofman Georg Homuth Jennie Hui Wilmar Igl Carlos Iribarren Bo Isomaa Kevin B Jacobs Ivonne Jarick Elizabeth Jewell Ulrich John Torben Jørgensen Pekka Jousilahti Antti Jula Marika Kaakinen Eero Kajantie Lee M Kaplan Sekar Kathiresan Johannes Kettunen Leena Kinnunen Joshua W Knowles Ivana Kolcic Inke R König Seppo Koskinen Peter Kovacs Johanna Kuusisto Peter Kraft Kirsti Kvaløy Jaana Laitinen Olivier Lantieri Chiara Lanzani Lenore J Launer Cecile Lecoeur Terho Lehtimäki Guillaume Lettre Jianjun Liu Marja-Liisa Lokki Mattias Lorentzon Robert N Luben Barbara Ludwig Paolo Manunta Diana Marek Michel Marre Nicholas G Martin Wendy L McArdle Anne McCarthy Barbara McKnight Thomas Meitinger Olle Melander David Meyre Kristian Midthjell Grant W Montgomery Mario A Morken Andrew P Morris Rosanda Mulic Julius S Ngwa Mari Nelis Matt J Neville Dale R Nyholt Christopher J O'Donnell Stephen O'Rahilly Ken K Ong Ben Oostra Guillaume Paré Alex N Parker Markus Perola Irene Pichler Kirsi H Pietiläinen Carl G P Platou Ozren Polasek Anneli Pouta Suzanne Rafelt Olli Raitakari Nigel W Rayner Martin Ridderstråle Winfried Rief Aimo Ruokonen Neil R Robertson Peter Rzehak Veikko Salomaa Alan R Sanders Manjinder S Sandhu Serena Sanna Jouko Saramies Markku J Savolainen Susann Scherag Sabine Schipf Stefan Schreiber Heribert Schunkert Kaisa Silander Juha Sinisalo David S Siscovick Jan H Smit Nicole Soranzo Ulla Sovio Jonathan Stephens Ida Surakka Amy J Swift Mari-Liis Tammesoo Jean-Claude Tardif Maris Teder-Laving Tanya M Teslovich John R Thompson Brian Thomson Anke Tönjes Tiinamaija Tuomi Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Jorma Viikari Sophie Visvikis-Siest Veronique Vitart Carla I G Vogel Benjamin F Voight Lindsay L Waite Henri Wallaschofski G Bragi Walters Elisabeth Widen Susanna Wiegand Sarah H Wild Gonneke Willemsen Daniel R Witte Jacqueline C Witteman Jianfeng Xu Qunyuan Zhang Lina Zgaga Andreas Ziegler Paavo Zitting John P Beilby I Sadaf Farooqi Johannes Hebebrand Heikki V Huikuri Alan L James Mika Kähönen Douglas F Levinson Fabio Macciardi Markku S Nieminen Claes Ohlsson Lyle J Palmer Paul M Ridker Michael Stumvoll Jacques S Beckmann Heiner Boeing Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock Francis S Collins L Adrienne Cupples George Davey Smith Jeanette Erdmann Philippe Froguel Henrik Grönberg Ulf Gyllensten Per Hall Torben Hansen Tamara B Harris Andrew T Hattersley Richard B Hayes Joachim Heinrich Frank B Hu Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Jaakko Kaprio Fredrik Karpe Kay-Tee Khaw Lambertus A Kiemeney Heiko Krude Markku Laakso Debbie A Lawlor Andres Metspalu Patricia B Munroe Willem H Ouwehand Oluf Pedersen Brenda W Penninx Annette Peters Peter P Pramstaller Thomas Quertermous Thomas Reinehr Aila Rissanen Igor Rudan Nilesh J Samani Peter E H Schwarz Alan R Shuldiner Timothy D Spector Jaakko Tuomilehto Manuela Uda André Uitterlinden Timo T Valle Martin Wabitsch Gérard Waeber Nicholas J Wareham Hugh Watkins James F Wilson Alan F Wright M Carola Zillikens Nilanjan Chatterjee Steven A McCarroll Shaun Purcell Eric E Schadt Peter M Visscher Themistocles L Assimes Ingrid B Borecki Panos Deloukas Caroline S Fox Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Karen L Mohlke Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Cornelia M van Duijn H-Erich Wichmann Timothy M Frayling Unnur Thorsteinsdottir Gonçalo R Abecasis Inês Barroso Michael Boehnke Kari Stefansson Kari E North Mark I McCarthy Joel N Hirschhorn Erik Ingelsson Ruth J F Loos

Nat Genet 2010 Nov 10;42(11):937-48. Epub 2010 Oct 10.

Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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November 2010

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

Authors:
Hana Lango Allen Karol Estrada Guillaume Lettre Sonja I Berndt Michael N Weedon Fernando Rivadeneira Cristen J Willer Anne U Jackson Sailaja Vedantam Soumya Raychaudhuri Teresa Ferreira Andrew R Wood Robert J Weyant Ayellet V Segrè Elizabeth K Speliotes Eleanor Wheeler Nicole Soranzo Ju-Hyun Park Jian Yang Daniel Gudbjartsson Nancy L Heard-Costa Joshua C Randall Lu Qi Albert Vernon Smith Reedik Mägi Tomi Pastinen Liming Liang Iris M Heid Jian'an Luan Gudmar Thorleifsson Thomas W Winkler Michael E Goddard Ken Sin Lo Cameron Palmer Tsegaselassie Workalemahu Yurii S Aulchenko Asa Johansson M Carola Zillikens Mary F Feitosa Tõnu Esko Toby Johnson Shamika Ketkar Peter Kraft Massimo Mangino Inga Prokopenko Devin Absher Eva Albrecht Florian Ernst Nicole L Glazer Caroline Hayward Jouke-Jan Hottenga Kevin B Jacobs Joshua W Knowles Zoltán Kutalik Keri L Monda Ozren Polasek Michael Preuss Nigel W Rayner Neil R Robertson Valgerdur Steinthorsdottir Jonathan P Tyrer Benjamin F Voight Fredrik Wiklund Jianfeng Xu Jing Hua Zhao Dale R Nyholt Niina Pellikka Markus Perola John R B Perry Ida Surakka Mari-Liis Tammesoo Elizabeth L Altmaier Najaf Amin Thor Aspelund Tushar Bhangale Gabrielle Boucher Daniel I Chasman Constance Chen Lachlan Coin Matthew N Cooper Anna L Dixon Quince Gibson Elin Grundberg Ke Hao M Juhani Junttila Lee M Kaplan Johannes Kettunen Inke R König Tony Kwan Robert W Lawrence Douglas F Levinson Mattias Lorentzon Barbara McKnight Andrew P Morris Martina Müller Julius Suh Ngwa Shaun Purcell Suzanne Rafelt Rany M Salem Erika Salvi Serena Sanna Jianxin Shi Ulla Sovio John R Thompson Michael C Turchin Liesbeth Vandenput Dominique J Verlaan Veronique Vitart Charles C White Andreas Ziegler Peter Almgren Anthony J Balmforth Harry Campbell Lorena Citterio Alessandro De Grandi Anna Dominiczak Jubao Duan Paul Elliott Roberto Elosua Johan G Eriksson Nelson B Freimer Eco J C Geus Nicola Glorioso Shen Haiqing Anna-Liisa Hartikainen Aki S Havulinna Andrew A Hicks Jennie Hui Wilmar Igl Thomas Illig Antti Jula Eero Kajantie Tuomas O Kilpeläinen Markku Koiranen Ivana Kolcic Seppo Koskinen Peter Kovacs Jaana Laitinen Jianjun Liu Marja-Liisa Lokki Ana Marusic Andrea Maschio Thomas Meitinger Antonella Mulas Guillaume Paré Alex N Parker John F Peden Astrid Petersmann Irene Pichler Kirsi H Pietiläinen Anneli Pouta Martin Ridderstråle Jerome I Rotter Jennifer G Sambrook Alan R Sanders Carsten Oliver Schmidt Juha Sinisalo Jan H Smit Heather M Stringham G Bragi Walters Elisabeth Widen Sarah H Wild Gonneke Willemsen Laura Zagato Lina Zgaga Paavo Zitting Helene Alavere Martin Farrall Wendy L McArdle Mari Nelis Marjolein J Peters Samuli Ripatti Joyce B J van Meurs Katja K Aben Kristin G Ardlie Jacques S Beckmann John P Beilby Richard N Bergman Sven Bergmann Francis S Collins Daniele Cusi Martin den Heijer Gudny Eiriksdottir Pablo V Gejman Alistair S Hall Anders Hamsten Heikki V Huikuri Carlos Iribarren Mika Kähönen Jaakko Kaprio Sekar Kathiresan Lambertus Kiemeney Thomas Kocher Lenore J Launer Terho Lehtimäki Olle Melander Tom H Mosley Arthur W Musk Markku S Nieminen Christopher J O'Donnell Claes Ohlsson Ben Oostra Lyle J Palmer Olli Raitakari Paul M Ridker John D Rioux Aila Rissanen Carlo Rivolta Heribert Schunkert Alan R Shuldiner David S Siscovick Michael Stumvoll Anke Tönjes Jaakko Tuomilehto Gert-Jan van Ommen Jorma Viikari Andrew C Heath Nicholas G Martin Grant W Montgomery Michael A Province Manfred Kayser Alice M Arnold Larry D Atwood Eric Boerwinkle Stephen J Chanock Panos Deloukas Christian Gieger Henrik Grönberg Per Hall Andrew T Hattersley Christian Hengstenberg Wolfgang Hoffman G Mark Lathrop Veikko Salomaa Stefan Schreiber Manuela Uda Dawn Waterworth Alan F Wright Themistocles L Assimes Inês Barroso Albert Hofman Karen L Mohlke Dorret I Boomsma Mark J Caulfield L Adrienne Cupples Jeanette Erdmann Caroline S Fox Vilmundur Gudnason Ulf Gyllensten Tamara B Harris Richard B Hayes Marjo-Riitta Jarvelin Vincent Mooser Patricia B Munroe Willem H Ouwehand Brenda W Penninx Peter P Pramstaller Thomas Quertermous Igor Rudan Nilesh J Samani Timothy D Spector Henry Völzke Hugh Watkins James F Wilson Leif C Groop Talin Haritunians Frank B Hu Robert C Kaplan Andres Metspalu Kari E North David Schlessinger Nicholas J Wareham David J Hunter Jeffrey R O'Connell David P Strachan H-Erich Wichmann Ingrid B Borecki Cornelia M van Duijn Eric E Schadt Unnur Thorsteinsdottir Leena Peltonen André G Uitterlinden Peter M Visscher Nilanjan Chatterjee Ruth J F Loos Michael Boehnke Mark I McCarthy Erik Ingelsson Cecilia M Lindgren Gonçalo R Abecasis Kari Stefansson Timothy M Frayling Joel N Hirschhorn

Nature 2010 Oct 29;467(7317):832-8. Epub 2010 Sep 29.

Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter EX1 2LU, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955183PMC
October 2010

Effect of Ginkgo biloba on blood pressure and incidence of hypertension in elderly men and women.

Am J Hypertens 2010 May 18;23(5):528-33. Epub 2010 Feb 18.

Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.

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http://dx.doi.org/10.1038/ajh.2010.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989407PMC
May 2010

Long-term retention of older adults in the Cardiovascular Health Study: implications for studies of the oldest old.

J Am Geriatr Soc 2010 Apr;58(4):696-701

Center for Aging and Population Health, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Room 515, Pittsburgh, Pennsylvania 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903735PMC
April 2010

Total and cause-specific mortality in the cardiovascular health study.

J Gerontol A Biol Sci Med Sci 2009 Dec 1;64(12):1251-61. Epub 2009 Sep 1.

Departments of Epidemiology and Medicine, University of Pittsburgh, 130 North Bellefield Avenue Room 532, Pittsburgh, PA 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773812PMC
December 2009

Left atrial volume and geometry in healthy aging: the Cardiovascular Health Study.

Circ Cardiovasc Imaging 2009 Jul 11;2(4):282-9. Epub 2009 May 11.

University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA.

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http://dx.doi.org/10.1161/CIRCIMAGING.108.826602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156514PMC
July 2009

High frequency of and factors associated with thyroid hormone over-replacement and under-replacement in men and women aged 65 and over.

J Clin Endocrinol Metab 2009 Apr 6;94(4):1342-5. Epub 2009 Jan 6.

Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1210/jc.2008-1696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682480PMC
April 2009

Associations of pentraxin 3 with cardiovascular disease and all-cause death: the Cardiovascular Health Study.

Arterioscler Thromb Vasc Biol 2009 Apr 22;29(4):594-9. Epub 2009 Jan 22.

Department of Pathology, University of Vermont, Colchester, VT 05446, USA.

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http://dx.doi.org/10.1161/ATVBAHA.108.178947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661204PMC
April 2009

Long-term function in an older cohort--the cardiovascular health study all stars study.

J Am Geriatr Soc 2009 Mar 29;57(3):432-40. Epub 2009 Jan 29.

Department ofEpidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2008.02152.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736556PMC
March 2009

Prevalence, prognosis, and implications of isolated minor nonspecific ST-segment and T-wave abnormalities in older adults: Cardiovascular Health Study.

Circulation 2008 Dec 8;118(25):2790-6. Epub 2008 Dec 8.

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.108.772541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729590PMC
December 2008

White matter grade and ventricular volume on brain MRI as markers of longevity in the cardiovascular health study.

Neurobiol Aging 2007 Sep 20;28(9):1307-15. Epub 2006 Jul 20.

Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, 130 N. Bellefield Ave., Rm. 550, Pittsburgh, PA 15213, United States.

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http://dx.doi.org/10.1016/j.neurobiolaging.2006.06.010DOI Listing
September 2007

Association of carotid artery intima-media thickness, plaques, and C-reactive protein with future cardiovascular disease and all-cause mortality: the Cardiovascular Health Study.

Circulation 2007 Jul 18;116(1):32-8. Epub 2007 Jun 18.

National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, MSC 1061, Bldg 10, Room B1D-416, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.106.645606DOI Listing
July 2007

Serum amyloid P and cardiovascular disease in older men and women: results from the Cardiovascular Health Study.

Arterioscler Thromb Vasc Biol 2007 Feb 30;27(2):352-8. Epub 2006 Nov 30.

Department of Pathology, College of Medicine, University of Vermont, 208 South Park Drive, Suite 2, Colchester, VT 05446, USA.

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http://dx.doi.org/10.1161/01.ATV.0000254150.97741.feDOI Listing
February 2007

Association between levels of blood pressure and measures of subclinical disease multi-ethnic study of atherosclerosis.

Am J Hypertens 2006 Nov;19(11):1110-7

Cardiovascular Health Research Unit, Department of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington 98101, USA.

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http://dx.doi.org/10.1016/j.amjhyper.2006.04.002DOI Listing
November 2006

Thyroid status, cardiovascular risk, and mortality in older adults.

JAMA 2006 Mar;295(9):1033-41

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104-6021, USA.

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http://dx.doi.org/10.1001/jama.295.9.1033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1387822PMC
March 2006

Left atrial volume, geometry, and function in systolic and diastolic heart failure of persons > or =65 years of age (the cardiovascular health study).

Am J Cardiol 2006 Jan 15;97(1):83-9. Epub 2005 Nov 15.

Division of Cardiology, University of Maryland Medical Center, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/j.amjcard.2005.07.126DOI Listing
January 2006

Subclinical brain magnetic resonance imaging abnormalities predict physical functional decline in high-functioning older adults.

J Am Geriatr Soc 2005 Apr;53(4):649-54

Department of Epidemiology, School of Public Health, University of Pittsburgh, 130 N. Bellefield Avenue, Pittsburgh, PA 15260, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2005.53214.xDOI Listing
April 2005

A national neuroimaging database: a call to action.

AJNR Am J Neuroradiol 2004 Jun-Jul;25(6):908-9

The Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, Baltimore, MD 21287, USA.

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October 2004

White matter hyperintensity on cranial magnetic resonance imaging: a predictor of stroke.

Stroke 2004 Aug 3;35(8):1821-5. Epub 2004 Jun 3.

Department of Epidemiology, University of Pittsburgh, 130 N. Bellefield Avenue, Room 550, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1161/01.STR.0000132193.35955.69DOI Listing
August 2004

A national neuroimaging database: a call to action.

Acad Radiol 2004 Jul;11(7):829-31

The Russell H. Morgan Department of Radiology and Radiological Sciences, The Johns Hopkins Hospital, 600 N. Wolfe Street/Phipps B-112, Baltimore, MD 21287, USA.

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July 2004

Prevalence of specific variant carotid geometric patterns and incidence of cardiovascular events in older persons. The Cardiovascular Health Study (CHS E-131).

J Am Coll Cardiol 2004 Jan;43(2):187-93

Laboratory of Cardiovascular Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1016/j.jacc.2003.08.035DOI Listing
January 2004

"Successful aging": effect of subclinical cardiovascular disease.

Arch Intern Med 2003 Oct;163(19):2315-22

Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1001/archinte.163.19.2315DOI Listing
October 2003