Ali Shamseddine

Department of Internal Medicine, Hematology and Oncology, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut, Lebanon.

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August 2020

Ga-Prostate-Specific Membrane Antigen, A Potential Radiopharmaceutical in PET/CT To detect primary Cholangiocarcinoma.

Authors:

Rita Chahinian Ahmad El-Amine Sayed Matar Mostafa Annan Ali Shamseddine Mohamad Haidar

Asia Ocean J Nucl Med Biol 2020 ;8(2):136-140

Department of Clinical Diagnostic Radiology, American University of Beirut Medical Center, Riad El Solh, Beirut, Lebanon.

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January 2020

CYR61/CCN1 expression in resected pancreatic ductal adenocarcinoma: A retrospective pilot study of the interaction between the tumors and their surrounding microenvironment.

Authors:

Wassim Abou-Kheir Deborah Mukherji Ola Hadadeh Eman Saleh Hisham F Bahmad Mariam Kanso Mohamad Khalifeh Ali Shamseddine Sally Tamraz Rola Jaafar Christelle Dagher Ibrahim Khalifeh Walid Faraj

Heliyon 2020 May 3;6(5):e03842. Epub 2020 May 3.

Department of Surgery, Division of General Surgery, Liver Transplantation and Hepatopancreaticobiliary (HPB) Unit, American University of Beirut Medical Center, Beirut, Lebanon.

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May 2020

Resistance Mechanisms to Anti-angiogenic Therapies in Cancer.

Authors:

Yolla Haibe Malek Kreidieh Hiba El Hajj Ibrahim Khalifeh Deborah Mukherji Sally Temraz Ali Shamseddine

Front Oncol 2020 27;10:221. Epub 2020 Feb 27.

Division of Hematology/Oncology, Department of Internal Medicine, American University of Beirut-Medical Center, Beirut, Lebanon.

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February 2020

Exosomal Non Coding RNA in LIQUID Biopsies as a Promising Biomarker for Colorectal Cancer.

Authors:

Amro Baassiri Farah Nassar Deborah Mukherji Ali Shamseddine Rihab Nasr Sally Temraz

Int J Mol Sci 2020 Feb 19;21(4). Epub 2020 Feb 19.

Department of Internal Medicine, Hematology/Oncology division, American University of Beirut Medical Center, Riad El Solh, Beirut 1107, Lebanon.

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February 2020

Expanding the Scope of Immunotherapy in Colorectal Cancer: Current Clinical Approaches and Future Directions.

Authors:

Malek Kreidieh Deborah Mukherji Sally Temraz Ali Shamseddine

Biomed Res Int 2020 25;2020:9037217. Epub 2020 Jan 25.

Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.

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November 2020

High-Cost Cancer Treatment Across Borders in Conflict Zones: Experience of Iraqi Patients in Lebanon.

Authors:

Mac Skelton Raafat Alameddine Omran Saifi Miza Hammoud Maya Zorkot Marilyne Daher Maya Charafeddine Sally Temraz Ali Shamseddine Layth Mula-Hussain Mohammed Saleem Kazim F Namiq Omar Dewachi Ghassan Abu Sitta Zahi Abdul-Sater Talar Telvizian Walid Faraj Deborah Mukherji

JCO Glob Oncol 2020 02;6:59-66

Department of Hematology/Oncology, American University of Beirut Medical Center, Beirut, Lebanon.

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February 2020

Gut Microbiome: A Promising Biomarker for Immunotherapy in Colorectal Cancer.

Authors:

Sally Temraz Farah Nassar Rihab Nasr Maya Charafeddine Deborah Mukherji Ali Shamseddine

Int J Mol Sci 2019 Aug 25;20(17). Epub 2019 Aug 25.

Department of Internal Medicine, Hematology/Oncology Division, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.

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August 2019

Management of patients with high-risk and advanced prostate cancer in the Middle East: resource-stratified consensus recommendations.

World J Urol 2020 Mar 11;38(3):681-693. Epub 2019 Jul 11.

Division of Urology, Department of Surgery, American University of Beirut Medical Center, Riad El Solh, 1107 2020, Beirut, Lebanon.

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March 2020

Female oncologists in the Middle East and North Africa: progress towards gender equality.

Authors:

Rana Salem Yolla Haibe Christelle Dagher Charelle Salem Ali Shamseddine Nizar Bitar Joseph Makdessi Sami Khatib Hamouda Boussen Farouk Benna Sana Al Sukhun Nagi El Saghir Sally Temraz Deborah Mukherji

ESMO Open 2019 14;4(3):e000487. Epub 2019 Jun 14.

Department of Internal Medicine, American University of Beirut Medical Center, NK Basile Cancer Institute, Beirut, Lebanon.

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June 2019

The Combination of Stereotactic Body Radiation Therapy and Immunotherapy in Primary Liver Tumors.

Authors:

Malek Kreidieh Youssef H Zeidan Ali Shamseddine

J Oncol 2019 28;2019:4304817. Epub 2019 Apr 28.

Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.

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April 2019

Maximizing response: a case report of salvage chemotherapy after immune checkpoint inhibition in a patient with previous chemo-refractory metastatic esophageal carcinoma.

Authors:

Megan Greally Rajiv Agarwal Imane El Dika Ali Shamseddine Ashwaq El-Olayan Yolla Haibe Viktoriya Paroder Jinru Shia Ghassan K Abou-Alfa Geoffrey Y Ku

J Gastrointest Oncol 2019 Apr;10(2):367-372

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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April 2019

EMT Markers in Locally-Advanced Prostate Cancer: Predicting Recurrence?

Front Oncol 2019 11;9:131. Epub 2019 Mar 11.

Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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March 2019

Proportion of cancers attributable to major lifestyle and environmental risk factors in the Eastern Mediterranean region.

Authors:

Ivana Kulhánová Ariana Znaor Kevin D Shield Melina Arnold Jérôme Vignat Maya Charafeddine Ibtihal Fadhil Heba Fouad Amal Al-Omari Ali Saeed Al-Zahrani Amani El-Basmy Ali Shamseddine Freddie Bray Isabelle Soerjomataram

Int J Cancer 2020 02 29;146(3):646-656. Epub 2019 Apr 29.

Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.

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February 2020

Pancreaticoduodenectomy in the Middle East: Achieving optimal results through specialization and standardization.

Authors:

Walid Faraj Hussein Nassar Ahmad Zaghal Deborah Mukherji Ali Shamseddine Mariam Kanso Rola F Jaafar Mohamad Khalife

Hepatobiliary Pancreat Dis Int 2019 Oct 21;18(5):478-483. Epub 2019 Feb 21.

Liver Transplantation and Hepatopancreaticobiliary Surgery, Department of General Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

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October 2019

The unveiling of a new risk factor associated with bladder cancer in Lebanon.

Authors:

Sally Temraz Yolla Haibe Maya Charafeddine Omran Saifi Deborah Mukherji Ali Shamseddine

BMC Urol 2019 Mar 5;19(1):16. Epub 2019 Mar 5.

Department of Internal Medicine, American University of Beirut Medical Center, P.o.Box: 11-0236, Riad El Solh, Riad El Solh, Beirut, 110 72020, Lebanon.

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March 2019

Ascorbic Acid in Colon Cancer: From the Basic to the Clinical Applications.

Authors:

Ibrahim El Halabi Rachelle Bejjany Rihab Nasr Deborah Mukherji Sally Temraz Farah J Nassar Haidar El Darsa Ali Shamseddine

Int J Mol Sci 2018 Sep 13;19(9). Epub 2018 Sep 13.

Department of Internal Medicine-Division of Hematology-Oncology, American University of Beirut Medical Center, Riad El Solh, Beirut 1107 2020, Lebanon.

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September 2018

Ki67 and P53 in Relation to Disease Progression in Metastatic Pancreatic Cancer: a Single Institution Analysis.

Authors:

Sally Temraz Ali Shamseddine Deborah Mukherji Maya Charafeddine Arafat Tfayli Hazem Assi Miza Salim Hammoud Iman Makki Samer Nassif

Pathol Oncol Res 2019 Jul 5;25(3):1059-1066. Epub 2018 Sep 5.

Department of Pathology & Laboratory Medicine, American University of Beirut Medical Center, Riad El Solh, Beirut, 110 72020, Lebanon.

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July 2019

Reduced Contrast Volume and Radiation Dose During Computed Tomography of the Pancreas: Timing-Specific Contrast Media Protocol.

Authors:

Charbel Saade Jad Chokr Lena Naffaa Walid Faraj Ali Shamseddine Deborah Mukherji Skye El Sayegh Rita Assi Ali Haydar

Acad Radiol 2019 04 17;26(4):480-488. Epub 2018 Aug 17.

Diagnostic Radiology Department, American University of Beirut Medical Center, P.O. Box: 11-0236 Riad El-Solh, Beirut 1107 2020, Lebanon. Electronic address:

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April 2019

Perceptions of Cancer Status Disclosure in Lebanon.

Authors:

Sally Temraz Miza Salim Hammoud Ahmad Saleh Maya Charafeddine Deborah Mukherji Ali Shamseddine

J Cancer Educ 2019 Oct;34(5):874-881

Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, Beirut, 1107 2020, Lebanon.

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October 2019

Inflammatory Markers and MicroRNAs: The Backstage Actors Influencing Prognosis in Colorectal Cancer Patients.

Authors:

Rihab Nasr Miza Salim Hammoud Farah Nassar Deborah Mukherji Ali Shamseddine Sally Temraz

Int J Mol Sci 2018 06 26;19(7). Epub 2018 Jun 26.

Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, Beirut 110 72020, Lebanon.

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June 2018

Primary synovial sarcoma of the kidney: a case report of complete pathological response at a Lebanese tertiary care center.

Authors:

Alissar El Chediak Deborah Mukherji Sally Temraz Samer Nassif Sara Sinno Rami Mahfouz Ali Shamseddine

BMC Urol 2018 May 11;18(1):40. Epub 2018 May 11.

Department of Internal Medicine, Division of Hematology/Oncology, American University of Beirut - Medical Center, P.o.Box: 11-0236, Riad El Solh, Beirut, 110 72020, Lebanon.

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May 2018

Increase in spleen volume as a predictor of oxaliplatin toxicity.

Authors:

Alissar El Chediak Ali A Haydar Ayman Hakim Sarah Abdel Massih Lara Hilal Deborah Mukherji Sally Temraz Ali Shamseddine

Ther Clin Risk Manag 2018 11;14:653-657. Epub 2018 Apr 11.

Department of Internal Medicine, Division of Hematology-Oncology, American University of Beirut-Medical Center, Beirut, Lebanon.

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April 2018

Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer.

Authors:

Rami Fakih Mahmoud Rahal Lara Hilal Lana Hamieh Mohammed Dany Simone Karam Latifa Shehab Nagi S El Saghir Arafat Tfayli Ziad Salem Hazem Assi Sally Temraz Ali Shamseddine Deborah Mukherji

Indian J Palliat Care 2018 Jan-Mar;24(1):35-38

Naef K. Basile Cancer Institute, American University of Beirut Medical Centre, Beirut, Lebanon.

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February 2018

Appendiceal Mucinous Neoplasms: Diagnosis and Management.

Authors:

Walid L Shaib Rita Assi Ali Shamseddine Olatunji B Alese Charles Staley Bahar Memis Volkan Adsay Tanios Bekaii-Saab Bassel F El-Rayes

Oncologist 2018 01;23(1):137

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January 2018

Perceptions and Attitudes of Cancer Patients and Caregivers Towards Enrollment in Clinical Trials in Lebanon.

Authors:

Rana Salem Charbel Matar Rita Assi Raafat Alameddine Sally Temraz Ali Shamseddine Deborah Mukherji

J Cancer Educ 2019 04;34(2):334-338

Hematology and Oncology Division, Department of Internal Medicine, American University of Beirut, P.O. Box 113-6044, Beirut, Lebanon.

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April 2019

Distribution and Role of N-acetyltransferase 2 Genetic Polymorphisms in Bladder Cancer Risk in a Lebanese Population

Authors:

Rami Nasr Sally Temraz Deborah Mukherji Ali Shamseddine Reem Akika Sehrish Abbasi Raja Khauli Muhammad Bulbul Hani Tamim Nathalie K Zgheib

Asian Pac J Cancer Prev 2017 09 27;18(9):2561-2568. Epub 2017 Sep 27.

Division of Urology, Department of Surgery, American University of Beirut Faculty of Medicine, Beirut, Lebanon. Email:

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September 2017

Nadir PSA is a strong predictor of treatment outcome in intermediate and high risk localized prostate cancer patients treated by definitive external beam radiotherapy and androgen deprivation.

Authors:

Fady B Geara Muhammad Bulbul Raja B Khauli Therese Y Andraos Mirna Abboud Abdelatif Al Mousa Nasim Sarhan Ahmed Salem Hamza Ghatasheh Anoud Alnsour Zeina Ayoub Ibrahim Abu Gheida Maya Charafeddine Mohammed Shahait Ali Shamseddine Rami Abu Gheida Jamal Khader

Radiat Oncol 2017 Sep 7;12(1):149. Epub 2017 Sep 7.

Department of Radiation Oncology, King Hussein Cancer Center, Amman, Jordan.

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September 2017

Optimizing tumor immune response through combination of radiation and immunotherapy.

Authors:

Alissar El Chediak Ali Shamseddine Larry Bodgi Jean-Pierre Obeid Fady Geara Youssef H Zeidan

Med Oncol 2017 Aug 21;34(9):165. Epub 2017 Aug 21.

Department of Radiation Oncology, American University of Beirut Medical Center, Beirut, Lebanon.

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August 2017

Trends in lung cancer incidence in Lebanon by gender and histological type over the period 2005-2008.

Authors:

Sally Temraz Maya Charafeddine Deborah Mukherji Ali Shamseddine

J Epidemiol Glob Health 2017 09 29;7(3):161-167. Epub 2017 Apr 29.

Department of Internal Medicine, Hematology/Oncology Division, American University of Beirut Medical Center, Riad El Solh 110 72020, Beirut, Lebanon. Electronic address:

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September 2017

An elderly man with remote history of metastatic melanoma now with localized pancreas cancer and new liver masses.

Authors:

Neil Vasan Maria Ignez Braghiroli Alexander N Shoushtari Richard Kinh Gian Do Marcia Edelweiss Ali Shamseddine Walid Faraj Deborah Mukherji Ali Haydar Ashwaq Olayan Fouad Sabatin Rita Assi Imane El Dika Leonard B Saltz Ghassan K Abou-Alfa Eileen M O'Reilly

J Gastrointest Oncol 2017 Jun;8(3):596-602

Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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June 2017

Practice and Impact of Multidisciplinary Tumor Boards on Patient Management: A Prospective Study.

Authors:

Raghid N Charara Firas Y Kreidieh Rania A Farhat Karine A Al-Feghali Katia E Khoury Ali Haydar Lara Nassar Ghina Berjawi Ali Shamseddine Nagi S El Saghir

J Glob Oncol 2017 Jun 10;3(3):242-249. Epub 2016 Aug 10.

, . , , , , , and , American University of Beirut Medical Center, Beirut, Lebanon; , Institute for Health Metrics and Evaluation, Seattle, WA; , St Louis University Hospital, St Louis, MO; and , University Hospitals Case Medical Center, Cleveland, OH.

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June 2017

Younger age is an independent predictor of worse prognosis among Lebanese nonmetastatic breast cancer patients: analysis of a prospective cohort.

Authors:

Alissar El Chediak Raafat S Alameddine Ayman Hakim Lara Hilal Sarah Abdel Massih Lana Hamieh Deborah Mukherji Sally Temraz Maya Charafeddine Ali Shamseddine

Breast Cancer (Dove Med Press) 2017 10;9:407-414. Epub 2017 Jun 10.

Division of Hematology/Oncology, Department of Internal Medicine.

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June 2017

Appendiceal Mucinous Neoplasms: Diagnosis and Management.

Authors:

Walid L Shaib Rita Assi Ali Shamseddine Olatunji B Alese Charles Staley Bahar Memis Volkan Adsay Tanios Bekaii-Saab Bassel F El-Rayes

Oncologist 2017 09 29;22(9):1107-1116. Epub 2017 Jun 29.

Department of Hematology and Oncology, Atlanta, Georgia, USA.

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September 2017

Proportion of cancer in a Middle eastern country attributable to established risk factors.

Authors:

Maya A Charafeddine Sara H Olson Deborah Mukherji Sally N Temraz Ghassan K Abou-Alfa Ali I Shamseddine

BMC Cancer 2017 05 18;17(1):337. Epub 2017 May 18.

Department of Hematology-Oncology, American University of Beirut Medical Center, P.O Box 11-0236, Riad El Solh, Beirut, 1107 2020, Lebanon.

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May 2017

The Elusive Diagnosis of Primary Esophageal Lymphoma

Authors:

Rachel Abou Mrad Nadim El-Majzoub Ali Shamseddine Assaad Soweid

Turk J Haematol 2018 08 8;35(3):199. Epub 2017 Mar 8.

American University of Beirut Medical Center, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Beirut, Lebanon

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August 2018

Profile of cancer in the Eastern Mediterranean region: The need for action.

Authors:

Ivana Kulhánová Freddie Bray Ibtihal Fadhil Ali Saeed Al-Zahrani Amani El-Basmy Wagida A Anwar Amal Al-Omari Ali Shamseddine Ariana Znaor Isabelle Soerjomataram

Cancer Epidemiol 2017 04 6;47:125-132. Epub 2017 Mar 6.

Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France.

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April 2017

Prevalence of EGFR and ALK Mutations in Lung Adenocarcinomas in the Levant Area - a Prospective Analysis

Asian Pac J Cancer Prev 2017 01 1;18(1):107-114. Epub 2017 Jan 1.

American University of Beirut Medical Center, Department of Internal Medicine PO Box: 11-0236, Riad El Solh, Beirut 1107 2020, Beirut- Lebanon. Email:

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January 2017

The role of 68Ga-DOTA-NOC PET/CT in evaluating neuroendocrine tumors: real-world experience from two large neuroendocrine tumor centers.

Authors:

Mohamad Haidar Ali Shamseddine Emmanouil Panagiotidis Mario Jreige Deborah Mukherji Rita Assi Rayan Abousaid Toni Ibrahim Marwan M Haddad Sobhan Vinjamuri

Nucl Med Commun 2017 Feb;38(2):170-177

aDepartment of Nuclear Medicine, Royal Liverpool University Hospital, Liverpool, UK Departments of bRadiology cInternal Medicine, American University of Beirut dDepartment of Nuclear Medicine, Mount Lebanon Hospital eDepartment of Internal Medicine, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

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February 2017

Metastatic colorectal cancer presenting with bone marrow metastasis: a case series and review of literature.

Authors:

Rita Assi Deborah Mukherji Ali Haydar Maya Saroufim Sally Temraz Ali Shamseddine

J Gastrointest Oncol 2016 Apr;7(2):284-97

1 Department of Internal Medicine, Division of Hematology-Oncology, 2 Department of Radiology, 3 Department of Pathology, American University of Beirut Medical Center, Beirut 1103, Lebanon.

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April 2016

Dual targeting of HER3 and EGFR in colorectal tumors might overcome anti-EGFR resistance.

Authors:

Sally Temraz Deborah Mukherji Ali Shamseddine

Crit Rev Oncol Hematol 2016 May 10;101:151-7. Epub 2016 Mar 10.

Department of Internal Medicine, Hematology/Oncology Division, American University of Beirut Medical Center, Riad El Solh, 110 72020 Beirut, Lebanon.

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May 2016

Pancreatic neuroendocrine tumor with aneurysms of the gastroduodenal artery: a case report.

Authors:

Karim Rebeiz Ali Shamseddine Ralph Hachem Karen Brown Deborah Mukherji Walid Faraj Ghassan K Abou-Alfa Layla A Nasr Ali A Haydar

Clin Imaging 2016 Mar-Apr;40(2):228-31. Epub 2015 Nov 11.

American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

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November 2016

Gastrointestinal (GI) leiomyosarcoma (LMS) case series and review on diagnosis, management, and prognosis.

Authors:

Lara Hilal Kassem Barada Deborah Mukherji Sally Temraz Ali Shamseddine

Med Oncol 2016 Feb 20;33(2):20. Epub 2016 Jan 20.

Department of Internal Medicine, Naef K. Basile Cancer Institute, American University of Beirut Medical Center, Beirut, Lebanon.

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February 2016

Programmed Death-Ligand 1 Expression in Muscle-Invasive Bladder Cancer Cystectomy Specimens and Lymph Node Metastasis: A Reliable Treatment Selection Biomarker?

Authors:

Deborah Mukherji Mark N Jabbour Maya Saroufim Sally Temraz Rami Nasr Maya Charafeddine Rita Assi Ali Shamseddine Ayman N Tawil

Clin Genitourin Cancer 2016 Apr 17;14(2):183-7. Epub 2015 Dec 17.

Department of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

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April 2016

Leptomeningeal metastasis as initial manifestation of signet ring colorectal adenocarcinoma: a case report with review of literature.

Authors:

Rita Assi Lana Hamieh Deborah Mukherji Ali Haydar Sally Temraz Imane El-Dika Ali Shamseddine

J Gastrointest Oncol 2015 Dec;6(6):E89-E101

1 Department of Internal Medicine, Division of Hematology-Oncology, 2 Department of Radiology, American University of Beirut Medical Center, Beirut 1103, Lebanon.

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December 2015

A multicenter, phase II study of the RAF-kinase inhibitor sorafenib in patients with advanced renal cell carcinoma.

Authors:

Hussein Khaled Hamdy Abdel Azim Emad Barsoum George Chahine Ali Shamseddine Gamal Abdel Metaal Abbas Omar Abdul Rahman Jazeih Rasha Haggag Atef Badran

Mol Clin Oncol 2015 Sep 16;3(5):1099-1102. Epub 2015 Jul 16.

Department of Medical Oncology, National Cancer Institute, Cairo University, Cairo 11796, Egypt.

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September 2015

Liver resection for metastatic colorectal leiomyosarcoma: a single center experience.

Authors:

Walid Faraj Jessica El-Kehdy Ghina El Nounou Samer Deeba Hawraa Fakih Mark Jabbour Ali Haydar Abdallah Abou El Naaj Ghassan K Abou-Alfa Eileen M O'Reilly Ali Shamseddine Mohamad Khalife Deborah Mukherji

J Gastrointest Oncol 2015 Oct;6(5):E70-6

1 Liver Transplantation and Hepatopancreaticobiliary Surgery, Department of General Surgery, 2 Department of Surgery, 3 Division of Hematology and Oncology, Department of Internal Medicine, 4 Department of Pathology, American University of Beirut Medical Center, Beirut, Lebanon ; 5 Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA ; 6 Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

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October 2015

"This is not me": patient, family, cultural and clinician considerations in cases of severe cancer-related debility.

Authors:

Daneng Li Ghassan K Abou-Alfa Aaron D Viny Meredith Cammarata Ali Shamseddine Ashwaq Al-Olayan Hibah Osman Ali Haydar Ghassan Kanazi Mohamed Naghy Eileen M O'Reilly Andrew S Epstein

J Gastrointest Oncol 2015 Oct;6(5):589-93

1 Memorial Sloan Kettering Cancer Center, New York, NY, USA ; 2 Weill Cornell Medical College, New York, NY, USA ; 3 American University of Beirut, Beirut, Lebanon ; 4 National Guard Hospital at King Abdul-Aziz Medical City, Riyadh, Saudi Arabia.

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October 2015

Dual Inhibition of MEK and PI3K Pathway in KRAS and BRAF Mutated Colorectal Cancers.

Authors:

Sally Temraz Deborah Mukherji Ali Shamseddine

Int J Mol Sci 2015 Sep 23;16(9):22976-88. Epub 2015 Sep 23.

Department of Internal Medicine, Hematology/Oncology Division, American University of Beirut Medical Center, Beirut 110 72020, Lebanon.

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September 2015

New Compounds Targeting the Androgen Receptor for Treatment of Advanced Prostate Cancer.

Authors:

Rita Assi Sally Temraz Ali Shamseddine Deborah Mukherji

Curr Drug Targets 2016 ;17(3):290-302

Department of Internal Medicine, Division of Hematology Oncology American University of Beirut Medical Center Beirut, Lebanon.

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October 2016

Prostate Cancer in the Arab World: A View From the Inside.

Authors:

Lara Hilal Mohammad Shahait Deborah Mukherji Maya Charafeddine Zein Farhat Sally Temraz Raja Khauli Ali Shamseddine

Clin Genitourin Cancer 2015 Dec 6;13(6):505-11. Epub 2015 Jun 6.

Naef K. Basile Cancer Institute and Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

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December 2015

Cardiac and vascular toxicities of angiogenesis inhibitors: The other side of the coin.

Authors:

Raafat S Alameddine Ahmad Sharif Yakan Hadi Skouri Deborah Mukherji Sally Temraz Ali Shamseddine

Crit Rev Oncol Hematol 2015 Nov 16;96(2):195-205. Epub 2015 May 16.

Division of Hematology and Oncology, American University of Beirut, Beirut, Lebanon. Electronic address:

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November 2015

Liver-directed conversion therapy in metastatic colon cancer.

Authors:

Alexandra Snyder Nancy Kemeny Ali Shamseddine Ashwaq Al-Olayan Fadi El-Merhi David P Kelsen Faek Jamali Mustafa Sidani Deborah Mukherji Mahmoud El-Naghy Eileen M O'Reilly Leonard B Saltz Ghassan K Abou-Alfa

J Gastrointest Oncol 2015 Jun;6(3):322-8

1 Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA ; 2 Weill Cornell Medical College, New York, NY, USA ; 3 American University of Beirut, Beirut, Lebanon ; 4 National Guard Hospital at King Abdul-Aziz Medical City, Riyadh, Saudi Arabia.

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June 2015

Controversial indications for sentinel lymph node biopsy in breast cancer patients.

Authors:

Hazem Assi Eman Sbaity Mahmoud Abdelsalam Ali Shamseddine

Biomed Res Int 2015 3;2015:405949. Epub 2015 Mar 3.

Department of Internal Medicine, American University of Beirut Medical Center, Cairo Street, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon.

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December 2015

BRCA1 and BRCA2 mutations in ethnic Lebanese Arab women with high hereditary risk breast cancer.

Oncologist 2015 Apr 16;20(4):357-64. Epub 2015 Mar 16.

Division of Hematology-Oncology, Department of Internal Medicine, and Departments of Pharmacology and Toxicology, Surgery, and Obstetrics and Gynecology, American University of Beirut, Lebanon; University of Auvergne and Laboratoire Diagnostique Génétique et Moléculaire, Centre Jean Perrin, Clermont-Ferrand, France; Sidney Kimmel Comprehensive Cancer Center and Department of Gynecology and Obstetrics, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

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April 2015

B-type proto-oncogene-mutated tumors of colon cancer: promising therapeutic approaches.

Authors:

Sally Temraz Raafat Alameddine Ali Shamseddine

Curr Opin Oncol 2015 May;27(3):276-81

Division of Medical Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

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May 2015

Malignant fibrous histiocytoma presenting with complete opacification of the hemithorax: A case report.

Authors:

Jean Salem Ali Shamseddine Mohamad Khalife Ghina El Nounou Abdallah Abou El Naaj Deborah Mukherji Ali Haydar Walid Faraj

Int J Surg Case Rep 2014 11;5(12):1162-3. Epub 2014 Nov 11.

Department of Surgery, Division of General Surgery, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

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December 2014

Sunitinib Induced Thrombotic Thrombocytopenic Purpura in addition to Severe Hypothyroidism: A Case Report and Review of the Literature.

Authors:

Imane El Dika Deborah Mukherji Sally Temraz Rita Assi Ali Shamseddine

Case Rep Med 2014 7;2014:958414. Epub 2014 Oct 7.

Department of Internal Medicine, Division of Medical Oncology, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El-Solh, Beirut 1107 2020, Lebanon.

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October 2014

Challenges in combining antiangiogenic therapy with transarterial chemoembolization for hepatocellular carcinoma.

Authors:

Ali A Haydar Deborah Mukherji Walid Faraj Mohammad Khalifeh Bedros Taslakian Zeinab Abou Yehia Sally Temraz Karen T Brown Ghassan K Abou-Alfa Ali Shamseddine

Gastrointest Cancer Res 2014 May;7(3-4):98-102

Divison of Oncology.

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May 2014

Preoperative lymphocyte-to-monocyte ratio predicts clinical outcome in patients undergoing radical cystectomy for transitional cell carcinoma of the bladder: a retrospective analysis.

Authors:

Sally Temraz Deborah Mukherji Zein Al Abideen Farhat Rami Nasr Maya Charafeddine Mohammed Shahait Mohammad Rachad Wehbe Rami Abou Ghaida Ibrahim Abu Gheida Ali Shamseddine

BMC Urol 2014 Sep 19;14:76. Epub 2014 Sep 19.

Departments of Hematology-Oncology, Riad El Solh, Beirut, Lebanon.

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September 2014

From sprouting angiogenesis to erythrocytes generation by cancer stem cells: evolving concepts in tumor microcirculation.

Authors:

Raafat S Alameddine Lana Hamieh Ali Shamseddine

Biomed Res Int 2014 4;2014:986768. Epub 2014 Aug 4.

Division of Hematology and Oncology, Faculty of Medicine, American University of Beirut, P.O. Box 11-0236, Riad El Solh, Beirut 1107-2020, Lebanon.

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May 2015

Evolving treatment approaches for the management of metastatic castration-resistant prostate cancer - role of radium-223.

Authors:

Deborah Mukherji Imane El Dika Sally Temraz Mohammed Haidar Ali Shamseddine

Ther Clin Risk Manag 2014 23;10:373-80. Epub 2014 May 23.

Department of Hematology/Oncology, American University of Beirut Medical Center, Beirut, Lebanon.

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June 2014

Secondary bile acids: an underrecognized cause of colon cancer.

Authors:

Hana Ajouz Deborah Mukherji Ali Shamseddine

World J Surg Oncol 2014 May 24;12:164. Epub 2014 May 24.

Department of Hematology/Oncology, American University of Beirut Medical Center, PO Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon.

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May 2014

A 39-year-old female patient with metastatic rectal cancer develops thrombocytopenia.

Authors:

Haifaa Dbouk Simon Mentha Deborah Mukherji Jean Lee Ali Haydar Ali Shamseddine Eileen M O'Reilly Leonard Saltz Ghassan K Abou-Alfa

Gastrointest Cancer Res 2014 Mar;7(2):55-8

Memorial Sloan-Kettering Cancer Center New York, NY ; Weill Cornell Medical College New York, NY.

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March 2014

Sequencing of treatment in metastatic colorectal cancer: where to fit the target.

Authors:

Sally Temraz Deborah Mukherji Ali Shamseddine

World J Gastroenterol 2014 Feb;20(8):1993-2004

Sally Temraz, Deborah Mukherji, Ali Shamseddine, Division of Hematology/Oncology, Department of Internal Medicine, American University of Beirut Medical Center (AUBMC), Riad El Solh 110 72020, Beirut, Lebanon.

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February 2014

Cancer trends in Lebanon: a review of incidence rates for the period of 2003-2008 and projections until 2018.

Authors:

Ali Shamseddine Ahmad Saleh Maya Charafeddine Muhieddine Seoud Deborah Mukherji Sally Temraz Abla Mehio Sibai

Popul Health Metr 2014 Mar 4;12(1). Epub 2014 Mar 4.

Division of Hematology and Oncology, Department of Internal Medicine, American University of Beirut Medical Center, P,O Box 11-0236, Riad el Solh, Beirut 1107 2802, Lebanon.

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March 2014

A woman with metastatic pancreatic neuroendocrine tumor.

Authors:

Alexander N Shoushtari Anne M Covey Ghazi Zaatari Ali Shamseddine Andrew S Epstein Ali Haydar Mohamed Naghy Deborah Mukherji David P Kelsen Ghassan K Abou-Alfa Eileen M O'Reilly

Gastrointest Cancer Res 2014 Jan;7(1):27-32

Memorial Sloan-Kettering Cancer Center New York, NY ; Weill Medical College at Cornell University New York, NY.

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January 2014

Metastatic castration-resistant prostate cancer (CRPC): preclinical and clinical evidence for the sequential use of novel therapeutics.

Authors:

Deborah Mukherji Aurelius Omlin Carmel Pezaro Ali Shamseddine Johann de Bono

Cancer Metastasis Rev 2014 Sep;33(2-3):555-66

Department of Internal Medicine, Division of Hematology/Oncology, American University of Beirut Medical Center, PO box 11-0236, Riad El Solh, Beirut, 1107 2020, Lebanon,

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September 2014

Modified GTX as second-line therapy for advanced pancreatic adenocarcinoma.

Authors:

Hana Ajouz Deborah Mukherji Ali Haydar Ahmad Sharif Yakan Ahmad Saleh Elias Elias Sally Temraz Walid Faraj Mohammad Khalife Ali Shamseddine

J Gastrointest Cancer 2014 Mar;45(1):109-12

Division of Hematology and Oncology, American University of Beirut Medical Center, Beirut, Lebanon,

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March 2014

Metastatic castration resistant prostate cancer: current strategies of management in the Middle East.

Authors:

Shouki Bazarbashi Marwan Bachour Muhammad Bulbul Mohammed Alotaibi Mohamed Jaloudi Hassan Jaafar Deborah Mukherji Naim Farah Tahseen Alrubai Ali Shamseddine

Crit Rev Oncol Hematol 2014 Apr 8;90(1):36-48. Epub 2013 Nov 8.

Division of Hematology & Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. Electronic address:

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April 2014

Modified GTX as Second-Line Chemotherapy in Advanced Pancreatic Cancer.

Authors:

Haifa Dbouk Hana Ajouz Ali Shamseddine Deborah Mukherji Eileen M O'Reilly Ali Haydar David Kelsen Mohamed Naghy Mohamed Eloubeidi Fadi Geara Leonard Saltz Ghassan K Abou-Alfa

Gastrointest Cancer Res 2013 Jul;6(4):115-7

American University of Beirut Beirut, Lebanon.

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July 2013

Methods of overcoming treatment resistance in colorectal cancer.

Authors:

Sally Temraz Deborah Mukherji Raafat Alameddine Ali Shamseddine

Crit Rev Oncol Hematol 2014 Feb 8;89(2):217-30. Epub 2013 Sep 8.

American University of Beirut Medical Center (AUBMC), Lebanon.

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February 2014

Potential targets for colorectal cancer prevention.

Authors:

Sally Temraz Deborah Mukherji Ali Shamseddine

Int J Mol Sci 2013 Aug 22;14(9):17279-303. Epub 2013 Aug 22.

Division of Hematology/Oncology, American University of Beirut Medical Center, Beirut 1107 2020, Lebanon.

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August 2013

A 40-year-old woman with locally advanced rectal cancer and a solitary liver metastasis.

Authors:

Carla Hajj Karyn Goodman David Kelsen Jinru Shia Ali Shamseddine Mohamed Naghy Mustafa Sidani Mohamed Eloubeidi Fady Merhi Fady Geara Celina Ang Leonard Saltz Ghassan K Abou-Alfa

Gastrointest Cancer Res 2013 May;6(3):87-9

Memorial Sloan-Kettering Cancer Center New York, NY.

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May 2013

Pharmacogenomics variation in drug metabolizing enzymes and transporters in relation to docetaxel toxicity in Lebanese breast cancer patients: paving the way for OMICs in low and middle income countries.

Authors:

Zainab Awada Syed Haider Arafat Tfayli Ali Bazarbachi Nagi S El-Saghir Ziad Salem Ali Shamseddine Ali Taher Nathalie Khoueiry Zgheib

OMICS 2013 Jul 11;17(7):353-67. Epub 2013 Jun 11.

Department of Pharmacology and Toxicology, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.

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July 2013

Management of a patient diagnosed with pancreatic cancer and myelodysplastic syndrome.

Authors:

Elizabeth Won Kenneth H Yu Ali Shamseddine Leonard Saltz Deborah Mukherjee Ali Haydar Ashwaq El-Olayan Sally Temraz Mohamed Naghy Dorothy Makanjoula Eileen M O'Reilly Ghassan K Abou-Alfa

Gastrointest Cancer Res 2013 Mar;6(2):56-60

Memorial Sloan-Kettering Cancer Center New York, NY.

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March 2013

Postoperative outcomes following pancreaticoduodenectomy: how should age affect clinical practice?

Authors:

Walid Faraj Raafat Alameddine Deborah Mukherji Khaled Musallam Ali Haydar Mohamed Eloubiedi Ali Shamseddine Ali Halal Ghassan K Abou-Alfa Eileen M O'Reilly Faek Jamali Mohamed Khalife

World J Surg Oncol 2013 Jun 6;11:131. Epub 2013 Jun 6.

Liver Transplantation and Hepatopancreaticobiliary Surgery, Department of General Surgery, American University of Beirut, Cairo Street, Beirut 1107 2020, Lebanon.

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June 2013

Genetic polymorphisms of CYP2E1, GST, and NAT2 enzymes are not associated with risk of breast cancer in a sample of Lebanese women.

Authors:

Nathalie K Zgheib Ashraf A Shamseddine Eddy Geryess Arafat Tfayli Ali Bazarbachi Ziad Salem Ali Shamseddine Ali Taher Nagi S El-Saghir

Mutat Res 2013 Jul-Aug;747-748:40-7. Epub 2013 Apr 27.

Department of Pharmacology & Toxicology, Faculty of Medicine, American University of Beirut, Lebanon.

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August 2013

Crosstalk between HER2 signaling and angiogenesis in breast cancer: molecular basis, clinical applications and challenges.

Authors:

Raafat S Alameddine Zaher K Otrock Ahmad Awada Ali Shamseddine

Curr Opin Oncol 2013 May;25(3):313-24

Department of Internal Medicine, Division of Hematology and Oncology, American University of Beirut Medical Center, Beirut, Lebanon.

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May 2013

A young woman with liver cancer.

Authors:

Celina S Ang Richard K Do Ali Shamseddine Eileen M O'Reilly Ali Haydar Ashwaq Al-Olayan Walid Faraj Fouad Boulos Mohamed Naghy Dorothy Makanjoula Hassan Farran Hassan Sibai David Wehbe David P Kelsen Ghassan K Abou-Alfa

Gastrointest Cancer Res 2013 Jan;6(1):17-21

Memorial Sloan-Kettering Cancer Center New York, NY.

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January 2013

Angiogenesis and anti-angiogenic therapy in prostate cancer.

Authors:

Deborah Mukherji Sally Temraz David Wehbe Ali Shamseddine

Crit Rev Oncol Hematol 2013 Aug 29;87(2):122-31. Epub 2013 Jan 29.

Department of Hematology/Oncology, American University of Beirut Medical Center, PO Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon.

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August 2013

Management of a locally advanced rectal cancer in a patient who declined surgery.

Authors:

Raafat Alameddine David Wehbe Martin Weiser Neil Segal Karyn Goodman Ali Shamseddine Celina Ang Ali Haydar Mustafa Sidani Fady Geara Mohamed Naghy Eileen M O'Reilly Ghassan K Abou-Alfa

Gastrointest Cancer Res 2012 Nov;5(6):205-9

American University of Beirut Beirut, Lebanon.

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November 2012

New treatment developments applied to elderly patients with advanced prostate cancer.

Authors:

Deborah Mukherji Carmel J Pezaro Ali Shamseddine Johann S De Bono

Cancer Treat Rev 2013 Oct 3;39(6):578-83. Epub 2013 Jan 3.

Department of Hematology/Oncology, American University of Beirut Medical Center, P.O. Box 11-0236, Riad El Solh, Beirut 1107 2020, Lebanon.

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October 2013

High-dose calcitriol, docetaxel and zoledronic acid in patients with castration-resistant prostate cancer: a phase II study.

Authors:

Ali Shamseddine Fadi S Farhat Elias Elias Raja B Khauli Ahmad Saleh Mohammad A Bulbul

Urol Int 2013 8;90(1):56-61. Epub 2012 Nov 8.

Division of Hematology/Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon. as04 @ aub.edu.lb

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July 2013

Neoadjuvant Therapy in Clinical Stage II Pancreatic Adenocarcinoma.

Authors:

Alexandra Snyder Peter Allen Ali Shamseddine Ali Haydar Mohamed Eloubeidi Walid Faraj Mohamed Khalife Sally Temraz Ashwaq El-Olayan David P Kelsen Fadi El-Merhi Mohamed Naghy Leonard B Saltz Ghassan K Abou-Alfa Eileen M O'Reilly

Gastrointest Cancer Res 2012 Sep;5(5):169-73

Memorial Sloan-Kettering Cancer Center New York, NY.

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September 2012

Lymph node ratio is an independent prognostic factor after resection of periampullary malignancies: data from a tertiary referral center in the middle East.

Authors:

Ali I Shamseddine Deborah Mukherji Christian Melki Elias Elias Mohammad Eloubeidi Hani Dimassi Mohammad Khalife Ghassan Abou-Alfa Eileen O'Reilly Walid Faraj

Am J Clin Oncol 2014 Feb;37(1):13-8

*Department of Internal Medicine, Division of Hematology and Oncology †Liver Transplantation and Hepatopancreaticobiliary Surgery, Department of General Surgery ‡Department of Internal Medicine, Division of Gastroenterology, American University of Beirut, Beirut §Lebanese American University, School of Pharmacy, Byblos, Lebanon ∥Memorial Sloan-Kettering Cancer Center, Section of Gastrointestinal Oncology, New York, NY.

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February 2014