Publications by authors named "Ali M Alalawi"

1 Publications

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Pharmacological activities of some new polycyclic triazolopyrazolopyridazine derivatives.

Int J Biol Macromol 2012 Jul-Aug;51(1-2):7-17. Epub 2012 May 8.

Pharmacy Department, College of Medical Rehabilitation Sciences, Taibah University, Madinah Munawara, Saudi Arabia.

In continuation of our previous work, a novel series of polycyclic derivatives were synthesized and their anti-inflammatory, analgesic and antimicrobial activities were evaluated. Initially the acute toxicity of the compounds was assayed via the determination of their LD(50). Some of the newly compounds exhibited better biological and pharmacological activities than the reference controls with low toxicity (LD(50)). The structure of the new compounds has been established on the bases of chemical and spectroscopic evidences. The detailed synthesis, spectroscopic data, LD(50) and pharmacological activities of the synthesized compounds were reported.
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October 2012