Publications by authors named "Ali Khosrobeigi"

3 Publications

  • Page 1 of 1

Evaluation of blood pressure in children with idiopathic overactive bladder syndrome.

Saudi J Kidney Dis Transpl 2018 May-Jun;29(3):540-544

Students Research Committee, Arak University of Medical Sciences, Arak, Iran.

Children with an overactive bladder generally exhibit frequency, urgency, and urge incontinence. Often, a child will squat to try to prevent urinary incontinence. The bladder in these children is not anatomically and is functionally, smaller than normal and exhibits strong uncontrolled contractions. The aim of this study was to the evaluation of blood pressure (BP) in children with idiopathic overactive bladder syndrome. In this case-control study, we selected 110 children with overactive bladder as cases and 220 children without overactive bladder as controls. Children with overactive bladder and healthy children without overactive bladder were enrolled, and their BP was measured in children. P <0.05 was considered statistically significant in our comparisons. The mean age of the children was 8.8 ± 1.70 and 8.53 ± 2.44 years in overactive bladder and control group, respectively. The mean systolic and diastolic BP were a significant difference between case and control groups (P = 0.001). Systolic and diastolic BP were significantly higher in children with overactive bladder.
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http://dx.doi.org/10.4103/1319-2442.235177DOI Listing
October 2019

Incidence of obsessive-compulsive disorder in children with nonmonosymptomatic primary nocturnal enuresis.

J Pediatr Neurosci 2016 Jul-Sep;11(3):197-199

Department of Pediatric Nephrology, School of Medicine, Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran; Department of Pediatrics, Factuality of Medicine, Amirkabir Hospital, Arak University of Medical Sciences, Arak, Iran.

Introduction: Enuresis is defined as the repeated voiding of urine into clothes or bed at least twice a week for at least 3 consecutive months in a child who is at least 5 years of age. The behavior is not due exclusively to the direct physiologic effect of a substance or a general medical condition. Diurnal enuresis defines wetting, whereas awake and nocturnal enuresis refers to voiding during sleep. Primary enuresis occurs in children who have never been consistently dry through the night, whereas secondary enuresis refers the resumption of wetting after at least 6 months of dryness. Monosymptomatic enuresis has no associated daytime symptoms, and nonmonosymptomatic enuresis, which is more common, often has at least one subtle daytime symptom. Monosymptomatic enuresis is rarely associated with significant organic underlying abnormalities. Obsessive-compulsive disorder (OCD) is a chronic disabling illness characterized by repetitive, ritualistic behaviors over which the patients have little or no control. The purpose of this study was to investigate the relationship between OCD and nonmonosymptomatic nocturnal enuresis (NMNE).

Materials And Methods: In this case-control study, we evaluated 186 children aged 6-17 years old who were visited in the pediatric clinics of Amir Kabir Hospital, Arak, Iran. The control group included 93 healthy children, and the case group included 93 age- and sex-matched children with stage 1-3 chronic kidney disease (CKD). Then, the children's behavioral status was evaluated using the Children's Yale-Brown Obsessive-Compulsive Scale.

Results: The difference in compulsion was significant ( = 0.021), whereas the difference in obsession was significant between the two groups ( = 0.013). The most common symptom in CKD children with compulsion was silent repetition of words.

Conclusion: Compulsive and obsessive are more common in NMNE versus healthy children. The observed correlation between compulsive-obsessive and NMNE makes psychological counseling mandatory in children with NMNE.
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http://dx.doi.org/10.4103/1817-1745.193371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108120PMC
November 2016

Effects of olive leaves extract on LDL oxidation induced-CuSO(4) in vitro.

Pak J Pharm Sci 2012 Jul;25(3):571-5

Razi Herbal Medicine Research Center, Lorestan University of Medical Sciences, Khoramabad, Iran.

Oxidation of low-density lipoprotein (LDL) has been strongly implicated in the pathogenesis of atherosclerosis. The use of some natural antioxidant and herbal medicine may lead to the inhibition of production of oxidized LDL and may decrease both the development and the progression of atherosclerosis. The aim of this study was to investigate the effects of Olive leaves ethanol extract (OLE) on LDL oxidation induced-CuSO(4) quantitatively in vitro. Low-density lipoprotein was incubated with CuSO(4) and the formation of conjugated dienes and thiobarbituric acid reactive substances (TBARS). Inhibition of this Cu-induced oxidation was studied in the presence of vitamin E and various concentration of OLE. It was demonstrated that OLE reduced the formation of conjugated dienes and TBARS of LDL against oxidation in vitro (p<0.05). The inhibitory effects of the OLE on LDL oxidation were dose-dependent at concentrations ranging from (2μg/ml) to (200μg/ml). Moreover, we compared effects of OLE on LDL oxidation with vitamin E as positive control. This study showed that OLE is a source of potent antioxidants and prevented the oxidation of LDL in vitro and it may be suitable for use in food and pharmaceutical applications.
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July 2012