Publications by authors named "Alfredo J Guerra"

15Publications

mSphere of Influence: Ushering in the CRISPR Revolution to Biology.

Authors:
Alfredo J Guerra

mSphere 2019 07 3;4(4). Epub 2019 Jul 3.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA

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July 2019

Development of a conditional localization approach to control apicoplast protein trafficking in malaria parasites.

Traffic 2019 08 17;20(8):571-582. Epub 2019 Jun 17.

Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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August 2019

Structural basis of Toxoplasma gondii perforin-like protein 1 membrane interaction and activity during egress.

PLoS Pathog 2018 12 4;14(12):e1007476. Epub 2018 Dec 4.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, United States of America.

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December 2018

Optimization of dipeptidic inhibitors of cathepsin L for improved Toxoplasma gondii selectivity and CNS permeability.

Bioorg Med Chem Lett 2018 06 9;28(10):1972-1980. Epub 2018 Mar 9.

Vahlteich Medicinal Chemistry Core, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, United States; Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, United States. Electronic address:

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June 2018

Structural Features of Apicomplexan Pore-Forming Proteins and Their Roles in Parasite Cell Traversal and Egress.

Toxins (Basel) 2017 08 29;9(9). Epub 2017 Aug 29.

Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109-5620, USA.

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August 2017

A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species.

Mol Microbiol 2017 Nov 8;106(3):439-451. Epub 2017 Sep 8.

Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

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November 2017

Crystal structure of lipoate-bound lipoate ligase 1, LipL1, from Plasmodium falciparum.

Proteins 2017 Sep 7;85(9):1777-1783. Epub 2017 Jun 7.

Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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September 2017

Solution NMR refinement of a metal ion bound protein using metal ion inclusive restrained molecular dynamics methods.

J Biomol NMR 2013 Jun 23;56(2):125-37. Epub 2013 Apr 23.

Department of Chemistry and the Quantum Theory Project, University of Florida, 2238 New Physics Building, P.O. Box 118435, Gainesville, FL 32611-8435, USA.

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June 2013

Energetics of zinc-mediated interactions in the allosteric pathways of metal sensor proteins.

J Am Chem Soc 2013 Jan 26;135(1):30-3. Epub 2012 Dec 26.

Department of Chemistry and Quantum Theory Project, University of Florida, Gainesville, Florida 32611-8435, United States.

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January 2013

Backbone and sterospecific methyl side chain resonance assignments of the homodimeric zinc sensor AdcR (32 kDa) in the apo- and Zn(II)-bound states.

Biomol NMR Assign 2014 Apr 9;8(1):11-4. Epub 2012 Nov 9.

Department of Chemistry, Indiana University, Bloomington, IN, 47405-7102, USA.

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April 2014

Metal site occupancy and allosteric switching in bacterial metal sensor proteins.

Arch Biochem Biophys 2012 Mar 8;519(2):210-22. Epub 2011 Dec 8.

Department of Chemistry, Indiana University, 212 S. Hawthorne Drive, Bloomington, IN 47405-7102, USA.

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March 2012

Crystal structure of the zinc-dependent MarR family transcriptional regulator AdcR in the Zn(II)-bound state.

J Am Chem Soc 2011 Dec 21;133(49):19614-7. Epub 2011 Nov 21.

Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.

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December 2011