Alfredo Fusco

Alfredo Fusco

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Alfredo Fusco

Publications by authors named "Alfredo Fusco"

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HMGA2 cooperates with either p27 deficiency or Cdk4 mutation in pituitary tumorigenesis.

Cell Cycle 2018 30;17(5):580-588. Epub 2018 Jan 30.

a CNR - Institute of Experimental Endocrinology and Oncology - c/o Department of Molecular Medicine and Medical Biotechnologies , University of Naples "Federico II" , Naples , Italy.

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http://dx.doi.org/10.1080/15384101.2017.1403682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969540PMC
September 2019

Emerging Role of USP8, HMGA, and Non-Coding RNAs in Pituitary Tumorigenesis.

Cancers (Basel) 2019 Sep 4;11(9). Epub 2019 Sep 4.

Istituto di Endocrinologia ed Oncologia Sperimentale-Consiglio Nazionale delle Ricerche (CNR) c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", 80131 Naples, Italy.

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http://dx.doi.org/10.3390/cancers11091302DOI Listing
September 2019

HMGA and Cancer: A Review on Patent Literatures.

Recent Pat Anticancer Drug Discov 2019 Sep 19. Epub 2019 Sep 19.

Istituto di Endocrinologia e Oncologia Sperimentale-CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", via Pansini 5, 80131 Naples. Italy.

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http://dx.doi.org/10.2174/1574892814666190919152001DOI Listing
September 2019

Role of Dicer1 in thyroid cell proliferation and differentiation.

Cell Cycle 2017 9;16(23):2282-2289. Epub 2017 Nov 9.

a Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS) "G. Salvatore", Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II" , Naples , Italy.

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http://dx.doi.org/10.1080/15384101.2017.1380127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788491PMC
July 2019

RPSAP52 lncRNA is overexpressed in pituitary tumors and promotes cell proliferation by acting as miRNA sponge for HMGA proteins.

J Mol Med (Berl) 2019 Jul 10;97(7):1019-1032. Epub 2019 May 10.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS) "G. Salvatore", Consiglio Nazionale delle Ricerche (CNR) c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli "Federico II", Via Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s00109-019-01789-7DOI Listing
July 2019

HMGA1 negatively regulates NUMB expression at transcriptional and post transcriptional level in glioblastoma stem cells.

Cell Cycle 2019 Jul 22;18(13):1446-1457. Epub 2019 May 22.

a Istituto di Endocrinologia ed Oncologia Sperimentale - CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche , Università degli Studi di Napoli "Federico II" , Naples , Italy.

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http://dx.doi.org/10.1080/15384101.2019.1618541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592240PMC
July 2019

The () Gene Acts as Tumor Suppressor in Breast Cancer.

Cancers (Basel) 2019 Jun 8;11(6). Epub 2019 Jun 8.

Institute for Experimental Endocrinology and Oncology (IEOS) "G. Salvatore", National Research Council (CNR), Via Sergio Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.3390/cancers11060797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627064PMC
June 2019

Oncogenic Properties of the Antisense lncRNA in - and -Driven Papillary Thyroid Carcinomas.

Cancer Res 2019 May 12;79(9):2124-2135. Epub 2019 Mar 12.

Institute of Genetics and Biophysics "Adriano Buzzati-Traverso," CNR, Naples, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-2520DOI Listing
May 2019

The complex CBX7-PRMT1 has a critical role in regulating E-cadherin gene expression and cell migration.

Biochim Biophys Acta Gene Regul Mech 2019 04 28;1862(4):509-521. Epub 2019 Feb 28.

Istituto di Endocrinologia ed Oncologia Sperimentale - CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbagrm.2019.02.006DOI Listing
April 2019

Characterization of inflammatory infiltrate of ulcerative dermatitis in C57BL/6NCrl-Tg(HMGA1P6)1Pg mice.

Lab Anim 2018 Dec 6:23677218815718. Epub 2018 Dec 6.

1 Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Italy.

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http://dx.doi.org/10.1177/0023677218815718DOI Listing
December 2018

HMGA2, but not HMGA1, is overexpressed in human larynx carcinomas.

Histopathology 2018 Jun 9;72(7):1102-1114. Epub 2018 Mar 9.

Programa de Carcinogênese Molecular, Instituto Nacional de Câncer - INCA, Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1111/his.13456DOI Listing
June 2018

Ionizing Radiation Deregulates the MicroRNA Expression Profile in Differentiated Thyroid Cells.

Thyroid 2018 03;28(3):407-421

1 Istituto di Endocrinologia ed Oncologia Sperimentale-CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II," Naples, Italy .

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http://dx.doi.org/10.1089/thy.2017.0458DOI Listing
March 2018

UBE2C Is a Transcriptional Target of the Cell Cycle Regulator FOXM1.

Genes (Basel) 2018 Mar 29;9(4). Epub 2018 Mar 29.

Programa de Carcinogênese Molecular, Instituto Nacional de Câncer-INCA, Rua Andre Cavalcanti 37, Rio de Janeiro 20231-050, RJ, Brazil.

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http://dx.doi.org/10.3390/genes9040188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924530PMC
March 2018

Retraction for Fusco et al., "A Oncogene-Containing Retrovirus, Myeloproliferative Sarcoma Virus, Transforms Rat Thyroid Epithelial Cells and Irreversibly Blocks Their Differentiation Pattern".

J Virol 2018 03 26;92(6). Epub 2018 Feb 26.

Centro di Endocrinologia ed Oncologia Sperimentale del CNR, c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Il Facoltà di Medicina e Chirurgia dell'Università di Napoli, 80131 Naples, Italy.

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http://dx.doi.org/10.1128/JVI.02169-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827388PMC
March 2018

High mobility group A1 protein modulates autophagy in cancer cells.

Cell Death Differ 2017 11 4;24(11):1948-1962. Epub 2017 Aug 4.

Department of Molecular Medicine and Medical Biotechnology, University of Naples 'Federico II' and Istituto di Endocrinologia ed Oncologia Sperimentale (IEOS) of CNR, Naples, Italy.

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http://dx.doi.org/10.1038/cdd.2017.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635219PMC
November 2017

The HMGA1 Pseudogene 7 Induces miR-483 and miR-675 Upregulation by Activating Egr1 through a ceRNA Mechanism.

Genes (Basel) 2017 Nov 17;8(11). Epub 2017 Nov 17.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli "Federico II", via Pansini, 5, 80131 Naples, Italy.

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http://dx.doi.org/10.3390/genes8110330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704243PMC
November 2017

Complementary actions of dopamine D2 receptor agonist and anti-vegf therapy on tumoral vessel normalization in a transgenic mouse model.

Int J Cancer 2017 05 14;140(9):2150-2161. Epub 2017 Feb 14.

CNRS, UMR-5203, Institut de Génomique Fonctionnelle, Département de Physiologie, Montpellier, F-34094, France.

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http://doi.wiley.com/10.1002/ijc.30628
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http://dx.doi.org/10.1002/ijc.30628DOI Listing
May 2017

Identification and Synthesis of Mycalol Analogues with Improved Potency against Anaplastic Thyroid Carcinoma Cell Lines.

J Nat Prod 2017 04 6;80(4):1125-1133. Epub 2017 Mar 6.

Istituto di Chimica Biomolecolare, Bio-Organic Chemistry Unit, Consiglio Nazionale delle Ricerche , Via Campi Flegrei 34, 80078, Pozzuoli, Naples, Italy.

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http://dx.doi.org/10.1021/acs.jnatprod.7b00043DOI Listing
April 2017

Critical role of HMGA proteins in cancer cell chemoresistance.

J Mol Med (Berl) 2017 04 14;95(4):353-360. Epub 2017 Mar 14.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, Via Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s00109-017-1520-xDOI Listing
April 2017

miR-155 is positively regulated by CBX7 in mouse embryonic fibroblasts and colon carcinomas, and targets the KRAS oncogene.

BMC Cancer 2017 03 4;17(1):170. Epub 2017 Mar 4.

Istituto di Endocrinologia ed Oncologia Sperimentale "G. Salvatore" - CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://dx.doi.org/10.1186/s12885-017-3158-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5336640PMC
March 2017

MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1.

Expert Opin Ther Targets 2015 24;19(8):1017-26. Epub 2015 Jun 24.

Università di Napoli "Federico II", Istituto per l'Endocrinologia e l'Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche , Naples , Italy +39 081 7464547 ; +39 081 7463749 ; +39 081 2296674 ; ;

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http://dx.doi.org/10.1517/14728222.2015.1057569DOI Listing
January 2017

Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities.

Cell Cycle 2016 ;15(6):812-8

a Istituto di Endocrinologia ed Oncologia Sperimentale del CNR and Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli "Federico II" , Naples , Italy.

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http://www.tandfonline.com/doi/full/10.1080/15384101.2016.11
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http://dx.doi.org/10.1080/15384101.2016.1146835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845974PMC
December 2016

HMGA1P7-pseudogene regulates H19 and Igf2 expression by a competitive endogenous RNA mechanism.

Sci Rep 2016 11 22;6:37622. Epub 2016 Nov 22.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli "Federico II", via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1038/srep37622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118720PMC
November 2016

HMGA1 silencing reduces stemness and temozolomide resistance in glioblastoma stem cells.

Expert Opin Ther Targets 2016 10 8;20(10):1169-79. Epub 2016 Sep 8.

a Istituto di Endocrinologia ed Oncologia Sperimentale - CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche , Università degli Studi di Napoli 'Federico II,' Naples , Italy.

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http://dx.doi.org/10.1080/14728222.2016.1220543DOI Listing
October 2016

Tyrosine Phosphatase PTPRJ/DEP-1 Is an Essential Promoter of Vascular Permeability, Angiogenesis, and Tumor Progression.

Cancer Res 2016 09 30;76(17):5080-91. Epub 2016 Jun 30.

CRCHUM - Centre de recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Quebec, Canada. Institut du cancer de Montréal, Montréal, Quebec, Canada. Département de Médecine, Université de Montréal, Montréal, Quebec, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1071DOI Listing
September 2016

High Mobility Group A proteins in esophageal carcinomas.

Cell Cycle 2016 Sep 2;15(18):2410-3. Epub 2016 Aug 2.

a Programa de Carcinogênese Molecular, Instituto Nacional de Câncer - INCA, Rua André Cavalcanti , Rio de Janeiro , RJ , Brazil.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026802PMC
http://dx.doi.org/10.1080/15384101.2016.1215388DOI Listing
September 2016

UbcH10 overexpression is less pronounced in older colorectal cancer patients.

Int J Colorectal Dis 2016 Jul 7;31(7):1367-8. Epub 2016 Jan 7.

Unit of Colorectal Surgery, Department of Medical, Surgical, Neurological, Metabolic and Geriatric Sciences, Second University of Naples, Piazza Miraglia 2, 80138, Naples, Italy.

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http://dx.doi.org/10.1007/s00384-015-2481-6DOI Listing
July 2016

UbcH10 expression can predict prognosis and sensitivity to the antineoplastic treatment for colorectal cancer patients.

Mol Carcinog 2016 May 27;55(5):793-807. Epub 2015 Apr 27.

Institute of Experimental Endocrinology and Oncology (IEOS), National Research Council (CNR), Department of Molecular Medicine and Medical Biotechnology (DMMBM), University of Naples "Federico II", Via S. Pansini 5, Naples, Italy.

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http://dx.doi.org/10.1002/mc.22322DOI Listing
May 2016

Downregulation of miR-410 targeting the cyclin B1 gene plays a role in pituitary gonadotroph tumors.

Cell Cycle 2015 30;14(16):2590-7. Epub 2015 Jun 30.

a Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche ; Scuola di Medicina e Chirurgia di Napoli; Università degli Studi di Napoli "Federico II" ; Naples , Italy.

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http://dx.doi.org/10.1080/15384101.2015.1064207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614981PMC
May 2016

HMGA1-pseudogenes and cancer.

Oncotarget 2016 May;7(19):28724-35

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053758PMC
http://dx.doi.org/10.18632/oncotarget.7427DOI Listing
May 2016

The "next-generation" knowledge of papillary thyroid carcinoma.

Cell Cycle 2015 ;14(13):2018-21

a Institute of Genetics and Biophysics "Adriano Buzzati-Traverso," CNR ; Naples , Italy.

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http://dx.doi.org/10.1080/15384101.2015.1049786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614799PMC
April 2016

PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells.

Sci Rep 2016 04 29;6:25268. Epub 2016 Apr 29.

Institute of Experimental Endocrinology and Oncology (IEOS), National Research Council (CNR), 80131 Naples, Italy.

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http://dx.doi.org/10.1038/srep25268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4850481PMC
April 2016

Hmga2 is necessary for Otx2-dependent exit of embryonic stem cells from the pluripotent ground state.

BMC Biol 2016 Mar 31;14:24. Epub 2016 Mar 31.

Department of Molecular Medicine and Medical Biotechnology, University of Napoli Federico II, via S. Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1186/s12915-016-0246-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818510PMC
March 2016

HMGA1-pseudogene expression is induced in human pituitary tumors.

Cell Cycle 2015 ;14(9):1471-5

a Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche; Scuola di Medicina e Chirurgia di Napoli; Università degli Studi di Napoli "Federico II" , Naples , Italy.

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http://dx.doi.org/10.1080/15384101.2015.1021520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615119PMC
February 2016

HMGA1 overexpression is associated with a particular subset of human breast carcinomas.

J Clin Pathol 2016 Feb 6;69(2):117-21. Epub 2015 Aug 6.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS) "G. Salvatore", Consiglio Nazionale delle Ricerche (CNR), Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://jcp.bmj.com/content/early/2015/08/06/jclinpath-2015-2
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http://jcp.bmj.com/lookup/doi/10.1136/jclinpath-2015-202907
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http://dx.doi.org/10.1136/jclinpath-2015-202907DOI Listing
February 2016

miR-130b-3p Upregulation Contributes to the Development of Thyroid Adenomas Targeting CCDC6 Gene.

Eur Thyroid J 2015 Dec 21;4(4):213-21. Epub 2015 Nov 21.

Istituto di Endocrinologia ed Oncologia Sperimentale-CNR, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli 'Federico II', Naples, Italy; Instituto Nacional de Cancer (INCA), Rio de Janeiro, Brazil.

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http://dx.doi.org/10.1159/000441355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716415PMC
December 2015

Restoration of CBX7 expression increases the susceptibility of human lung carcinoma cells to irinotecan treatment.

Naunyn Schmiedebergs Arch Pharmacol 2015 Nov 28;388(11):1179-86. Epub 2015 Jul 28.

Institute of Experimental Endocrinology and Oncology (IEOS), National Research Council (CNR), Department of Molecular Medicine and Medical Biotechnology (DMMBM), University of Naples "Federico II", Via S. Pansini 5, Naples, Italy.

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http://link.springer.com/content/pdf/10.1007%2Fs00210-015-11
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http://link.springer.com/10.1007/s00210-015-1153-y
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http://dx.doi.org/10.1007/s00210-015-1153-yDOI Listing
November 2015

2-Iodohexadecanal inhibits thyroid cell growth in part through the induction of let-7f microRNA.

Mol Cell Endocrinol 2015 Oct 16;414:224-32. Epub 2015 Jul 16.

Nuclear Biochemistry Division, Argentine National Atomic Energy Commission, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.07.007DOI Listing
October 2015

HMGA1-pseudogene overexpression contributes to cancer progression.

Cell Cycle 2014 ;13(23):3636-9

a Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli ; Università degli Studi di Napoli "Federico II," ; Naples , Italy.

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http://dx.doi.org/10.4161/15384101.2014.974440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613653PMC
September 2015

The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites.

J Biochem 2015 Sep 10;158(3):235-43. Epub 2015 Jun 10.

Division of Molecular Neurobiology, Department of Neurobiology, National Institute for Basic Biology, Okazaki 444-8787, Japan; Department of Basic Biology, School of Life Science, The Graduate University for Advanced Studies (SOKENDAI), Okazaki 444-8787, Japan;

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http://jb.oxfordjournals.org/content/158/3/235.full.pdf
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http://jb.oxfordjournals.org/lookup/doi/10.1093/jb/mvv045
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http://dx.doi.org/10.1093/jb/mvv045DOI Listing
September 2015

CBX7 modulates the expression of genes critical for cancer progression.

PLoS One 2014 27;9(5):e98295. Epub 2014 May 27.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098295PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4035280PMC
August 2015

Deregulation of miR-183 and KIAA0101 in Aggressive and Malignant Pituitary Tumors.

Front Med (Lausanne) 2015 10;2:54. Epub 2015 Aug 10.

Centre de Recherche en Cancérologie de Lyon, INSERM U1052/CNRS UMR 5286 Centre Léon Bérard , Lyon , France ; Université Lyon 1, Université de Lyon , Lyon , France ; ProfileXpert, SFR-Est, CNRS UMR-S3453, INSERM US7 , Lyon , France.

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http://dx.doi.org/10.3389/fmed.2015.00054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530307PMC
August 2015

Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes.

Oncotarget 2015 Jul;6(19):17342-53

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR and Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli "Federico II", 80131, Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627312PMC
http://dx.doi.org/10.18632/oncotarget.3944DOI Listing
July 2015

Epigenetic Mechanisms Leading to Overexpression of HMGA Proteins in Human Pituitary Adenomas.

Front Med (Lausanne) 2015 8;2:39. Epub 2015 Jun 8.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Istituto per l'Endocrinologia e l'Oncologia Sperimentale del CNR, Università degli Studi di Napoli "Federico II" , Naples , Italy ; Instituto Nacional de Câncer - INCA , Rio de Janeiro, Rio de Janeiro , Brazil.

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http://dx.doi.org/10.3389/fmed.2015.00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469109PMC
July 2015

Polycomb protein family member CBX7 plays a critical role in cancer progression.

Am J Cancer Res 2015 15;5(5):1594-601. Epub 2015 Apr 15.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli "Federico II" Via S. Pansini 5, 80131 Naples, Italy ; Instituto Nacional de Câncer - INCA Rua André Cavalcanti, 37-Centro, Rio de Janeiro, CEP 20231-050 RJ, Brazil.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4497428PMC
July 2015

Expression of CD133 in differentiated thyroid cancer of young patients.

J Clin Pathol 2015 Jun 13;68(6):434-40. Epub 2015 Mar 13.

Department of Pathology, CHU Sainte Justine, Université de Montréal, Montréal, Quebec, Canada Department of Pathology, Centre Hospitalier Universitaire Robert Debre, Université Paris 7, Paris, France.

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http://dx.doi.org/10.1136/jclinpath-2014-202625DOI Listing
June 2015

Ccdc6 knock-in mice develop thyroid hyperplasia associated to an enhanced CREB1 activity.

Oncotarget 2015 Jun;6(17):15628-38

Istituto per l'Endocrinologia ed Oncologia Sperimentale del CNR e/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558175PMC
http://dx.doi.org/10.18632/oncotarget.3858DOI Listing
June 2015

High mobility group a proteins as tumor markers.

Front Med (Lausanne) 2015 25;2:15. Epub 2015 Mar 25.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II , Naples , Italy ; Instituto Nacional de Câncer , Rio de Janeiro , Brazil.

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http://dx.doi.org/10.3389/fmed.2015.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373383PMC
April 2015

Inhibitory effects of 2-iodohexadecanal on FRTL-5 thyroid cells proliferation.

Mol Cell Endocrinol 2015 Mar 2;404:123-31. Epub 2015 Feb 2.

Nuclear Biochemistry Division, National Atomic Energy Commission, Buenos Aires, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2015.01.038DOI Listing
March 2015

The cl2/dro1/ccdc80 null mice develop thyroid and ovarian neoplasias.

Cancer Lett 2015 Feb 9;357(2):535-41. Epub 2014 Dec 9.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS) "G. Salvatore", Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli "Federico II", Via S. Pansini 5, Naples 80131, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.12.010DOI Listing
February 2015

CBX7 and HMGA1b proteins act in opposite way on the regulation of the SPP1 gene expression.

Oncotarget 2015 Feb;6(5):2680-92

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS) "G. Salvatore", Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli "Federico II", 80131 Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413610PMC
http://dx.doi.org/10.18632/oncotarget.2777DOI Listing
February 2015

miR-142-3p down-regulation contributes to thyroid follicular tumorigenesis by targeting ASH1L and MLL1.

J Clin Endocrinol Metab 2015 Jan;100(1):E59-69

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (M.C., F.P., E.R., A.U.B., A.F., S.B., A.F.), Università degli Studi di Napoli "Federico II," 80131 Naples, Italy; Department of Pathology (M. D-P.), Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Université Lyon 1, 69495 Pierre Bénite, France; CEINGE (M.G., L.D.V.), Biotecnologie Avanzate, 80145 Naples, Italy; Istituto dei Tumori di Napoli "G. Pascale" (C.A., G.C.) Via Mariano Semmola, 52, 80131 Naples, Italy; Dipartimento di Patologia Chirurgica, Medica, Molecolare e dell'Area Critica (L.T.), University of Pisa, I-56126 Pisa, Italy; and Instituto Nacional de Câncer (A.F.), 20230-130 Rio de Janeiro, RJ, Brazil.

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http://dx.doi.org/10.1210/jc.2014-2280DOI Listing
January 2015

CBX7 Expression in Oncocytic Thyroid Neoplastic Lesions (Hürthle Cell Adenomas and Carcinomas).

Eur Thyroid J 2014 Dec 15;3(4):211-6. Epub 2014 Oct 15.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS), Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli 'Federico II', Naples, Italy.

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https://www.karger.com/Article/FullText/367989
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http://dx.doi.org/10.1159/000367989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311303PMC
December 2014

High mobility group A1 protein expression reduces the sensitivity of colon and thyroid cancer cells to antineoplastic drugs.

BMC Cancer 2014 Nov 20;14:851. Epub 2014 Nov 20.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o, Università di Napoli Federico II, Via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1186/1471-2407-14-851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247615PMC
November 2014

CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation.

Biol Open 2014 Sep 4;3(9):871-9. Epub 2014 Sep 4.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR e/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", 80131 Naples, Italy

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http://bio.biologists.org/cgi/doi/10.1242/bio.20147872
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http://dx.doi.org/10.1242/bio.20147872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163664PMC
September 2014

HMGA1 pseudogenes as candidate proto-oncogenic competitive endogenous RNAs.

Oncotarget 2014 Sep;5(18):8341-54

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226687PMC
http://dx.doi.org/10.18632/oncotarget.2202DOI Listing
September 2014

NCOA4 transcriptional coactivator inhibits activation of DNA replication origins.

Mol Cell 2014 Jul 5;55(1):123-37. Epub 2014 Jun 5.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR/Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università di Napoli "Federico II," 80131 Naples, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765140036
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http://dx.doi.org/10.1016/j.molcel.2014.04.031DOI Listing
July 2014

H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC.

Oncotarget 2014 Jul;5(14):5736-49

Centro di Ingegneria Genetica e Biotecnologie Avanzate (CEINGE), Naples, Italy; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università 'Federico II' di Naples, Italy; Azienda Ospedaliera Federico II, DAI Medicina Trasfusionale Virologia, Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170634PMC
http://dx.doi.org/10.18632/oncotarget.2169DOI Listing
July 2014

Mir-23b and miR-130b expression is downregulated in pituitary adenomas.

Mol Cell Endocrinol 2014 Jun 28;390(1-2):1-7. Epub 2014 Mar 28.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Scuola di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli "Federico II", Naples, Italy. Electronic address:

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http://linkinghub.elsevier.com/retrieve/pii/S030372071400084
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http://dx.doi.org/10.1016/j.mce.2014.03.002DOI Listing
June 2014

HMGA1 silencing restores normal stem cell characteristics in colon cancer stem cells by increasing p53 levels.

Oncotarget 2014 May;5(10):3234-45

Istituto di Endocrinologia ed Oncologia Sperimentale - CNR e/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli "Federico II", Naples, Italy.

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http://www.oncotarget.com/fulltext/1914
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102806PMC
http://dx.doi.org/10.18632/oncotarget.1914DOI Listing
May 2014

Hmga1/Hmga2 double knock-out mice display a "superpygmy" phenotype.

Biol Open 2014 Apr 11;3(5):372-8. Epub 2014 Apr 11.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli "Federico II", via Pansini 5, 80131 Naples, Italy

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http://dx.doi.org/10.1242/bio.20146759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4021359PMC
April 2014

Deregulation of microRNA expression in thyroid neoplasias.

Nat Rev Endocrinol 2014 Feb 19;10(2):88-101. Epub 2013 Nov 19.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale (IEOS) "G. Salvatore", Consiglio Nazionale delle Ricerche (CNR), c/o Dipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), Università degli Studi di Napoli "Federico II", via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1038/nrendo.2013.223DOI Listing
February 2014

A miRNA signature associated with human metastatic medullary thyroid carcinoma.

Endocr Relat Cancer 2013 Dec 14;20(6):809-23. Epub 2013 Oct 14.

Departments of Endocrine Neoplasia and Hormonal Disorders Experimental Therapeutics Urology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA Department of Oncology, The University of Naples, Naples, Italy Department of Pathology, Centro Oncologico Fiorentino, Sesto Fiorentino, Florence, Italy Verna and Marrs McLean Department of Biochemistry and Molecular Biology Baylor College of Medicine, Houston, Texas, USA Department of Oncology, Istituto Toscano Tumori, Hospital of Prato, Prato, Italy Department of Gynecologic Oncology, Center for RNA Interference and Non-coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA Department of Endocrinology, University of Messina, Messina, Italy Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA Department of Internal Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1530/ERC-13-0357DOI Listing
December 2013

Mycalol: a natural lipid with promising cytotoxic properties against human anaplastic thyroid carcinoma cells.

Angew Chem Int Ed Engl 2013 Aug 15;52(35):9256-60. Epub 2013 Jul 15.

Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via Campi Flegrei 34, 80078, Pozzuoli, Napoli, Italy.

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http://dx.doi.org/10.1002/anie.201303039DOI Listing
August 2013

Tumor suppressor role of the CL2/DRO1/CCDC80 gene in thyroid carcinogenesis.

J Clin Endocrinol Metab 2013 Jul 10;98(7):2834-43. Epub 2013 May 10.

Istituto per l'Endocrinologia e l'Oncologia Sperimentale G Salvatore, Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università degli Studi di Napoli Federico II, Fondazione Pascale, 80131 Napoli, Italy.

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http://dx.doi.org/10.1210/jc.2012-2926DOI Listing
July 2013

DNA methylation state of the galectin-3 gene represents a potential new marker of thyroid malignancy.

Oncol Lett 2013 Jul 18;6(1):86-90. Epub 2013 Apr 18.

Department of Cellular and Molecular Biology and Pathology, University of Naples, Institute of Experimental Endocrinology and Oncology CNR, Naples, Italy ;

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http://dx.doi.org/10.3892/ol.2013.1312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742793PMC
July 2013

The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression.

Mol Oncol 2013 Jun 17;7(3):531-42. Epub 2013 Jan 17.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1016/j.molonc.2013.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528467PMC
June 2013

Up-regulation of miR-146b and down-regulation of miR-200b contribute to the cytotoxic effect of histone deacetylase inhibitors on ras-transformed thyroid cells.

J Clin Endocrinol Metab 2013 Jun 29;98(6):E1031-40. Epub 2013 Mar 29.

Istituto di Endocrinologia ed Oncologia Sperimentale-Consiglio Nazionale delle Ricerche c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II and European School of Molecular Medicine, Naples 80131, Italy.

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http://dx.doi.org/10.1210/jc.2012-4092DOI Listing
June 2013

The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin.

Eur J Cancer 2013 Mar 10;49(5):1142-51. Epub 2012 Nov 10.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1016/j.ejca.2012.10.014DOI Listing
March 2013