Alfred L George

Ann Neurol 2019 Dec 24;86(6):899-912. Epub 2019 Oct 24.

Departments of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL.

J Am Coll Cardiol 2019 Dec;74(23):2952-2953

Heart Rhythm 2019 Oct 5. Epub 2019 Oct 5.

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Electronic address:

Eur Heart J 2019 Sep;40(35):2964-2975

Istituto Auxologico Italiano, IRCCS, Center for Cardiac Arrhythmias of Genetic Origin, Milan, Italy.

Cell Calcium 2019 Sep 30;82:102063. Epub 2019 Jul 30.

Center for Arrhythmia Research and Therapeutics, Vanderbilt University Medical Center, Nashville, TN 37240, USA.

Circ Genom Precis Med 2019 Sep 27;12(9):375-385. Epub 2019 Aug 27.

From the Department of Pharmacology (L.M.W., F.P., P.W.B., A.L.G.), Northwestern University Feinberg School of Medicine, Chicago, IL.

PLoS One 2019 13;14(9):e0220415. Epub 2019 Sep 13.

Center for Structural Biology, Vanderbilt University, Nashville, Tennessee, United States of America.

Ann Clin Transl Neurol 2019 Sep 15;6(9):1606-1615. Epub 2019 Jul 15.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

J Physiol 2019 Aug 20;597(16):4293-4307. Epub 2019 May 20.

Department of Physiology, Northwestern University, Chicago, IL, 60611, USA.

J Am Coll Cardiol 2019 Aug;74(6):759-770

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Heart Rhythm 2019 Feb 25;16(2):279-280. Epub 2018 Sep 25.

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Electronic address:

Comput Struct Biotechnol J 2019 1;17:206-214. Epub 2019 Feb 1.

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

Eur Heart J 2018 11;39(44):3925-3931

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Searle 8-510, East Superior Street, Chicago, IL, USA.

Circ Genom Precis Med 2018 11;11(11):e002345

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL (C.G.V., R.R.D., K.L.F., S.L.G., F.P., J.-M.D., A.L.G.).

Forensic Sci Med Pathol 2018 09 8;14(3):367-371. Epub 2018 Jun 8.

Section of Forensic Pediatric Medicine, Clinic of Laboratory Medicine, Oslo University Hospital, Oslo, Norway.

Neurobiol Dis 2018 07 19;115:29-38. Epub 2018 Mar 19.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA. Electronic address:

Trends Neurosci 2018 07 23;41(7):442-456. Epub 2018 Apr 23.

Department of Neurology, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

Epilepsia 2018 06 21;59(6):1166-1176. Epub 2018 May 21.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Structure 2018 05 5;26(5):683-694.e3. Epub 2018 Apr 5.

Department of Biochemistry, Vanderbilt University, Nashville, TN 37205, USA; Department of Chemistry, Vanderbilt University, Nashville, TN 37235, USA; Center for Structural Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

Clin Pharmacol Ther 2018 04 2;103(4):574-581. Epub 2018 Feb 2.

Department of Pharmacology, University of Liverpool, Liverpool, UK.

Epilepsia 2018 04 30;59(4):e56-e62. Epub 2018 Mar 30.

Robert's Program on Sudden Death in Pediatrics, Boston Children's Hospital, Boston, MA, USA.

J Clin Invest 2018 03 12;128(3):1043-1056. Epub 2018 Feb 12.

Department of Physiology and Biophysics.

Sci Adv 2018 03 7;4(3):eaar2631. Epub 2018 Mar 7.

Department of Biochemistry, Vanderbilt University, Nashville, TN 37240, USA.

Neurol Genet 2017 Dec 11;3(6):e198. Epub 2017 Dec 11.

Department of Pharmacology (J.D.C., C.G.V., A.L.G., J.A.K.), Northwestern University Feinberg School of Medicine, Chicago, IL; Human Genome and Stem Cell Research Center (F.K.), Biosciences Institute, University of Sao Paulo, Brazil; and Mendelics Análise Genomica (F.K.), Sao Paulo, Brazil.

Circ Cardiovasc Genet 2017 Oct;10(5)

From the Department of Chemistry (B.L., J.L.M., J.M.), Center for Structural Biology (B.L., J.L.M., B.M.K., K.C.T., H.H., C.R.S., J.M.), Department of Biochemistry (B.M.K., H.H., C.R.S.), and Department of Biostatistics (D.K.S., J.D.B.), Vanderbilt University, Nashville, TN; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN (B.M.K., C.R.S.); and Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL (C.G.V., A.L.G.).

Genome Biol 2017 09 14;18(1):170. Epub 2017 Sep 14.

Cardiovascular and Metabolic Sciences, Max-Delbrück-Center for Molecular Medicine (MDC) in the Helmholtz Association, Robert-Rössle-Str. 10, 13125, Berlin, Germany.

BMJ Case Rep 2017 Aug 7;2017. Epub 2017 Aug 7.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Int J Mol Sci 2017 Jul 27;18(8). Epub 2017 Jul 27.

CEINGE Biotecnologie Avanzate s.c.ar.l., 80145 Naples, Italy.

J Clin Invest 2017 Jun 22;127(7):2805-2814. Epub 2017 May 22.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

Sci Rep 2017 05 10;7(1):1682. Epub 2017 May 10.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Ann Clin Transl Neurol 2017 05 26;4(5):326-339. Epub 2017 Apr 26.

Department of Pharmacology Northwestern University Feinberg School of Medicine Chicago Illinois.

Cardiovasc Res 2017 Apr;113(5):531-541

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

Neurol Genet 2017 Apr 2;3(2):e139. Epub 2017 Mar 2.

Department of Pediatrics and Pediatric Neurology (H.R.), Georg August University, Göttingen, Germany; Division of Clinical Genetics (L.V.), Department of Pediatrics (T.N., M.T.S.) and Department of Neurology (M.T.S.), University of Utah, Salt Lake City; Center for Human Genetics (S.D.), University Hospitals and Case Western Reserve University, Cleveland, OH; Division of Pediatric Neurology (K.E.), Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN; Center for Human Genetics Research (L.O., M.M., K. Swoboda), Department of Neurology, Massachusetts General Hospital, Boston; Neurogenetics Unit (E.A.) and Epilepsy Research Group (E.A., F.A.), Montreal Neurological Hospital and Institute; Department of Neurology and Neurosurgery (E.A., F.A.), Department of Human Genetics (E.A.), and Department of Pediatrics (F.A.), McGill University, Quebec, Canada; Alternating Hemiplegia of Childhood Foundation (G.A., S.C., L.E., V.P.), Southfield, MI; BCBA (A. Belgrade), Belgrade Behavior Consulting, Chicago, IL; Department of Neurology (A. Brashear), Wake Forest School of Medicine, Winston-Salem, NC; Department of Pharmacology (A.L.G.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Pediatrics (A.L.), University of Florida College of Medicine, Jacksonville; Integrative Neuropsychology (J.M.), Fairlawn, OH; Association Française de l'Hémiplégie Alternante (D.P.), Paris, France; Rare Disease Innovation Unit (S.R.), Clinical Development Program, Biogen, Cambridge, MA; Department of Child Neurology (M.S.), National Center of Neurology and Psychiatry, Kodaira, Japan; Swedish Neuroscience Institute (M.S.d.M.), Swedish Medical Center, Seattle, WA; Department of Neurosurgery (K. Sweadner), Massachusetts General Hospital and Harvard Medical School, Boston; Neuroscience Institute (M.Z.), Children's Hospital of Orange County, CA; and Departments of Pediatrics and Neurology (K. Silver), University of Chicago and Comer Children's Hospital, Chicago, IL.

Circ Arrhythm Electrophysiol 2017 Apr;10(4)

From the Department of Medicine and Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN.

Proc Natl Acad Sci U S A 2017 02 30;114(7):1696-1701. Epub 2017 Jan 30.

Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.

Heart Rhythm 2016 10 1;13(10):2012-9. Epub 2016 Jul 1.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

Anal Chem 2016 09 12;88(17):8604-9. Epub 2016 Aug 12.

Department of Cell and Molecular Biology, Northwestern University Feinberg School of Medicine , Chicago, Illinois 60611, United States.

Sci Adv 2016 09 9;2(9):e1501228. Epub 2016 Sep 9.

Department of Biochemistry, Vanderbilt University, Nashville, TN 37240, USA.; Center for Structural Biology, Vanderbilt University, Nashville, TN 37240, USA.; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37240, USA.

Heart Rhythm 2016 08 7;13(8):1716-23. Epub 2016 May 7.

Krannert Institute of Cardiology and Division of Cardiology, Department of Medicine, Indiana University, Indianapolis, Indiana. Electronic address:

Mol Pharmacol 2016 07 2;90(1):52-60. Epub 2016 May 2.

Department of Pharmacology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois

Conf Proc IEEE Eng Med Biol Soc 2014 ;2014:6671-4

Trends Cardiovasc Med 2015 Oct 4;25(7):646-52. Epub 2015 Mar 4.

Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL; Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address:

Circ Arrhythm Electrophysiol 2015 Aug 28;8(4):933-41. Epub 2015 May 28.

From the Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL (F.P., A.L.G.); and Department of Medicine (F.P., J.D.K., A.L.G.) and Department of Pharmacology (T.M.B., A.L.G.), Vanderbilt University, Nashville, TN.

Circ Arrhythm Electrophysiol 2015 Aug;8(4):769-71

From the Department of Pharmacology and Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, IL.

Biochemistry 2015 Apr 15;54(16):2551-9. Epub 2015 Apr 15.

†Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States.

Gut Microbes 2014 Mar-Apr;5(2):192-201. Epub 2014 Mar 5.

Department of Pediatrics; Vanderbilt University; Nashville, TN USA.

PLoS One 2014 20;9(5):e97380. Epub 2014 May 20.

Department of Experimental Cardiology, Heart Failure Research Centre, Academic Medical Center, Amsterdam, The Netherlands.

Heart Rhythm 2015 Feb 18;12(2):423-4. Epub 2014 Nov 18.

Department of Pharmacology and Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address:

J Am Coll Cardiol 2015 Feb;65(4):367-374

Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy.

PLoS One 2014 4;9(4):e93808. Epub 2014 Apr 4.

Department of Biomedical Sciences for Health, University of Milan, Milan, Italy; IRCCS Galeazzi Orthopedic Institute, Milan, Italy.

Cardiovasc Res 2014 Nov 22;104(2):355-63. Epub 2014 Jul 22.

Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, 2215B Garland Avenue, Room 1285A MRB IV, Nashville, TN 37323-6602, USA Division of Clinical Pharmacology, Vanderbilt University School of Medicine, 2215B Garland Avenue, Room 1285A MRB IV, Nashville, TN 37323-6602, USA

Lancet Neurol 2014 Nov;13(11):1068-1070

Department of Pharmacology and Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address:

Circulation 2014 Nov;130(22):1971-80

From the Department of Pharmacology and Center for Pharmacogenomics, Northwestern University Feinberg School of Medicine, Chicago, IL.

Circ Cardiovasc Genet 2014 Oct 2;7(5):599-606. Epub 2014 Aug 2.

From the Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Medical Research Council (MRC) Centre for Molecular and Cellular Biology, (C.P.d.V., L.v.d.M., J.C.M.-S., V.A.C.), and Department of Internal Medicine (A.G., P.A.B.), Stellenbosch University, Stellenbosch, South Africa; Department of Statistics, University of Western Cape, Bellville, South Africa (L.v.d.M.); IRCCS Istituto Auxologico Italiano, Center for Cardiac Arrhythmias of Genetic Origin and Laboratory of Cardiovascular Genetics, Milan, Italy (L.C., P.J.S.); Department of Molecular Medicine, University of Pavia, Pavia, Italy (L.C.); Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany (L.C.); and Departments of Medicine and Pharmacology, and Institute for Integrative Genomics, Vanderbilt University, Nashville, TN (A.L.G.).

Ann Neurol 2014 Oct 19;76(4):529-540. Epub 2014 Sep 19.

Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.

J Mol Cell Cardiol 2014 Sep 8;74:115-24. Epub 2014 May 8.

Calcium Signals Laboratory, Department of Biomedical Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205; Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205. Electronic address:

PLoS One 2013 6;8(11):e78511. Epub 2013 Nov 6.

Cardiovascular Sciences and Genetics Research Centers, St George's University of London, London, United Kingdom.

Heart Rhythm 2014 Aug 9;11(8):1446-53. Epub 2014 May 9.

Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, Tennessee. Electronic address:

Epilepsia 2014 Aug 23;55(8):1274-83. Epub 2014 May 23.

Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, U.S.A.

Circ Cardiovasc Genet 2014 Aug 10;7(4):466-74. Epub 2014 Jun 10.

J Am Heart Assoc 2014 Jun 23;3(3):e000996. Epub 2014 Jun 23.

Department of Physiology, University of Kentucky College of Medicine, Lexington, KY (G.Y., F.H., A.R.H., J.S.).

Neurobiol Dis 2014 May 14;65:1-11. Epub 2014 Jan 14.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-0275, USA. Electronic address:

J Am Coll Cardiol 2014 Apr 19;63(14):1430-7. Epub 2014 Feb 19.

Departments of Medicine and Pharmacology, Vanderbilt University, Nashville, Tennessee. Electronic address:

Curr Opin Pharmacol 2014 Apr 11;15:47-52. Epub 2013 Dec 11.

Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA; Department of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

Circ Res 2014 Mar 21;114(7):1114-24. Epub 2014 Feb 21.

From the Departments of Medicine (H.S.H., M.F., A.L.G., B.C.K.), Biochemistry (C.N.J., W.J.C.), Chemistry (W.J.C.), and Pharmacology (A.L.G., B.C.K.), Vanderbilt University, Nashville, TN; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis (F.R.N., R.L.C.); Department of Pharmacology, University of California, Davis (Y.Y., L.P., D.M.B.); and Department of School of Biomedical Sciences and Pharmacy, University of Newcastle, New South Wales, Australia (K.W., D.L.).

Neurobiol Dis 2014 Feb 21;62:313-22. Epub 2013 Oct 21.

Department of Medicine, Vanderbilt University, Nashville, TN, USA. Electronic address:

J Am Coll Cardiol 2014 Feb 27;63(6):549-59. Epub 2013 Nov 27.

Heart Failure Research Center, Department of Clinical and Experimental Cardiology, Academic Medical Center, Amsterdam, the Netherlands. Electronic address:

Mol Pharmacol 2014 Jan 7;85(1):162-74. Epub 2013 Nov 7.

Department of Biology (Cardiovascular Therapeutic Area), Gilead Sciences, Inc., Foster City and Fremont, California (K.M.K., R.H., L.L., L.B., S.R.); Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee (A.L.G.).

Mol Oncol 2013 Dec 20;7(6):1019-30. Epub 2013 Jul 20.

Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA; Minimally Invasive Urology Center, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China. Electronic address:

Exp Neurol 2013 Oct 8;248:530-40. Epub 2013 Aug 8.

Section of Pharmacology, Department of Pharmacy & Drug Sciences, University of Bari-Aldo Moro, Bari, Italy. Electronic address:

Circ Arrhythm Electrophysiol 2013 Oct 4;6(5):960-6. Epub 2013 Sep 4.

Department of Pharmacology and Department of Medicine, Vanderbilt University, Nashville, TN; and Department of Engineering Management, Information, and Systems, Southern Methodist University, Dallas, TX.

Circ Cardiovasc Genet 2013 Aug 15;6(4):354-61. Epub 2013 Jul 15.

INSERM, UMR S956, Paris, France.

PLoS One 2013 29;8(1):e54979. Epub 2013 Jan 29.

Department of Medicine, Vanderbilt University, Nashville, TN, USA.

J Am Coll Cardiol 2013 Jul 15;62(3):169-180. Epub 2013 May 15.

Department of Cardiology, Heart Failure Research Centre, Academic Medical Centre, Amsterdam, the Netherlands; Princess Al Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University, Jeddah, Saudi Arabia.

Nat Genet 2013 Jul 26;45(7):822-4. Epub 2013 May 26.

Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK.

Int J Cardiol 2013 May 12;165(2):362-5. Epub 2012 Sep 12.

JAMA 2013 Apr;309(14):1473-82

Department of Molecular Medicine, University of Pavia, and Molecular Cardiology Laboratory, Fondazione IRRCCS Policlinico S Matteo, Pavia, Italy.

Circulation 2013 Mar 6;127(9):1009-17. Epub 2013 Feb 6.

Section of Cardiology, Department of Molecular Medicine, University of Pavia, Pavia, Italy.

J Gen Physiol 2013 Feb;141(2):193-202

Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA.

J Am Soc Nephrol 2013 Feb 14;24(3):329-30. Epub 2013 Feb 14.

J Clin Invest 2013 Jan 2;123(1):75-83. Epub 2013 Jan 2.

Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA.

J Biol Chem 2012 Dec 19;287(50):42001-8. Epub 2012 Oct 19.

Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA.

J Am Coll Cardiol 2012 Dec 14;60(24):2515-24. Epub 2012 Nov 14.

Department of Molecular Medicine, Section of Cardiology, University of Pavia, Pavia, Italy.

J Clin Invest 2012 Dec 26;122(12):4333-6. Epub 2012 Nov 26.

Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232, USA.

J Biol Chem 2012 Nov 2;287(47):39613-25. Epub 2012 Oct 2.

Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee 37232, USA.

J Am Coll Cardiol 2012 Aug 6;60(9):841-50. Epub 2012 Jun 6.

St. George's University of London, London, UK.

Heart Rhythm 2012 Jul 8;9(7):1113-4. Epub 2012 May 8.

Heart Rhythm 2012 Apr 7;9(4):590-7. Epub 2011 Nov 7.

Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232-0275, USA.

J Cardiovasc Pharmacol 2012 Mar;59(3):249-53

Laboratory of Cardiovascular Genetics, IRCCS Istituto Auxologico Italiano, Milan, Italy.

Circ Cardiovasc Genet 2012 Feb 18;5(1):91-9. Epub 2011 Nov 18.

Department of Medicine I, University Hospital Munich, Campus Grosshadern, Ludwig-Maximilians University, Munich, Germany.

Am J Physiol Heart Circ Physiol 2012 Feb 18;302(3):H782-9. Epub 2011 Nov 18.

Departments of Medicine and Pharmacology Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

PLoS One 2011 30;6(9):e25354. Epub 2011 Sep 30.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

J Am Soc Nephrol 2011 Nov 13;22(11):1955-8. Epub 2011 Oct 13.

Eur J Neurosci 2011 Oct 22;34(8):1268-75. Epub 2011 Aug 22.

Division of Biomedical Genetics, Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands.

Mol Ther 2011 Sep 5;19(9):1636-44. Epub 2011 Jul 5.

Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

Circulation 2011 Aug 8;124(9):1001-11. Epub 2011 Aug 8.

Department of Medicine, Vanderbilt University School of Medicine, 2215B Garland Ave, 1285 MRBIV Light Hall, Nashville, TN 37232-0575, USA.

Channels (Austin) 2011 Mar-Apr;5(2):161-72. Epub 2011 Mar 1.

Department of Biology,Gilead Sciences, Palo Alto, CA, USA.

Epilepsia 2011 May 31;52(5):1000-9. Epub 2011 Mar 31.

Department of Medicine, Vanderbilt University, Nashville, Tennessee 37232-0275, USA.

Circ Cardiovasc Genet 2011 Apr 15;4(2):139-44. Epub 2011 Feb 15.

Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232-0700, USA.

Proc Natl Acad Sci U S A 2011 Mar 14;108(13):5443-8. Epub 2011 Mar 14.

Department of Pharmacology and Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.