Publications by authors named "Alfonso Valencia"

100Publications

Detection of SARS-CoV-2 in a cat owned by a COVID-19-affected patient in Spain.

Proc Natl Acad Sci U S A 2020 10 18;117(40):24790-24793. Epub 2020 Sep 18.

Centre de Recerca en Sanitat Animal, Institut de Recerca i Tecnologia Agroalimentàries, Campus Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

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http://dx.doi.org/10.1073/pnas.2010817117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547282PMC
October 2020

Understanding oncogenicity of cancer driver genes and mutations in the cancer genomics era.

FEBS Lett 2020 Apr 1. Epub 2020 Apr 1.

Division of Biomedical Sciences, University of California Riverside School of Medicine, Riverside, CA, USA.

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http://dx.doi.org/10.1002/1873-3468.13781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7529711PMC
April 2020

On the inconsistent treatment of gene-protein-reaction rules in context-specific metabolic models.

Bioinformatics 2020 03;36(6):1986-1988

Tecnun School of Engineering, University of Navarra, San Sebastián 20018, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btz832DOI Listing
March 2020

Patient Dossier: Healthcare queries over distributed resources.

PLoS Comput Biol 2019 10 17;15(10):e1007291. Epub 2019 Oct 17.

Barcelona Supercomputing Center (BSC), Barcelona, Spain.

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http://dx.doi.org/10.1371/journal.pcbi.1007291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797086PMC
October 2019

Association of Anorexia Nervosa With Risk of Cancer: A Systematic Review and Meta-analysis.

JAMA Netw Open 2019 06 5;2(6):e195313. Epub 2019 Jun 5.

Department of Medicine, University of Valencia, INCLIVA Health Research Institute, Centro de Investigación en Red de Salud Mental (CIBERSAM), Valencia, Spain.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.5313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563572PMC
June 2019

Big data analytics for personalized medicine.

Curr Opin Biotechnol 2019 08 6;58:161-167. Epub 2019 Apr 6.

Barcelona Supercomputing Center (BSC), C/Jordi Girona 29, 08034, Barcelona, Spain; ICREA, Pg. Lluís Companys 23, 08010, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.copbio.2019.03.004DOI Listing
August 2019

Reviewer-coerced citation: case report, update on journal policy and suggestions for future prevention.

Bioinformatics 2019 09;35(18):3217-3218

Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btz071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748764PMC
September 2019

Intronic CNVs and gene expression variation in human populations.

PLoS Genet 2019 01 24;15(1):e1007902. Epub 2019 Jan 24.

Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1007902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345438PMC
January 2019

Epigenetic and Transcriptional Variability Shape Phenotypic Plasticity.

Bioessays 2018 02 18;40(2). Epub 2017 Dec 18.

MRC/BHF Cardiovascular Epidemiology Unit Department of Public Health and Primary Care, University of Cambridge, Cambridge, CB1 8RN, UK.

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http://dx.doi.org/10.1002/bies.201700148DOI Listing
February 2018

Precision medicine needs pioneering clinical bioinformaticians.

Brief Bioinform 2019 05;20(3):752-766

Spanish National Cancer Research Centre.

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http://dx.doi.org/10.1093/bib/bbx144DOI Listing
May 2019

APPRIS 2017: principal isoforms for multiple gene sets.

Nucleic Acids Res 2018 01;46(D1):D213-D217

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.

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http://dx.doi.org/10.1093/nar/gkx997DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753224PMC
January 2018

Comparison of algorithms for the detection of cancer drivers at subgene resolution.

Nat Methods 2017 Aug 17;14(8):782-788. Epub 2017 Jul 17.

Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California, USA.

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http://dx.doi.org/10.1038/nmeth.4364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5935266PMC
August 2017

ChiPPI: a novel method for mapping chimeric protein-protein interactions uncovers selection principles of protein fusion events in cancer.

Nucleic Acids Res 2017 Jul;45(12):7094-7105

Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre (CNIO), M.F.Almagro 3, 28029 Madrid, Spain.

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http://dx.doi.org/10.1093/nar/gkx423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5499553PMC
July 2017

LimTox: a web tool for applied text mining of adverse event and toxicity associations of compounds, drugs and genes.

Nucleic Acids Res 2017 07;45(W1):W484-W489

Biological Text Mining Unit, Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.

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http://dx.doi.org/10.1093/nar/gkx462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570141PMC
July 2017

Most Alternative Isoforms Are Not Functionally Important.

Trends Biochem Sci 2017 06 5;42(6):408-410. Epub 2017 May 5.

Current address: Life Sciences Department, Barcelona Supercomputing Center (BSC-CNS), 08034 Barcelona, Spain.

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http://dx.doi.org/10.1016/j.tibs.2017.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449685PMC
June 2017

Information Retrieval and Text Mining Technologies for Chemistry.

Chem Rev 2017 Jun 5;117(12):7673-7761. Epub 2017 May 5.

Life Science Department, Barcelona Supercomputing Centre (BSC-CNS) , C/Jordi Girona, 29-31, Barcelona E-08034, Spain.

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http://dx.doi.org/10.1021/acs.chemrev.6b00851DOI Listing
June 2017

Anna Tramontano 1957-2017.

Nat Struct Mol Biol 2017 05;24(5):431-432

Biozentrum, University of Basel and SIB Swiss Institute of Bioinformatics, Basel, Switzerland.

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http://dx.doi.org/10.1038/nsmb.3410DOI Listing
May 2017

CImbinator: a web-based tool for drug synergy analysis in small- and large-scale datasets.

Bioinformatics 2017 Aug;33(15):2410-2412

Structural Computational Biology Group, Structural Biology and Biocomputing Programme, CNIO (Spanish National Cancer Research Centre), Madrid, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btx161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860113PMC
August 2017

Conservation of coevolving protein interfaces bridges prokaryote-eukaryote homologies in the twilight zone.

Proc Natl Acad Sci U S A 2016 12 13;113(52):15018-15023. Epub 2016 Dec 13.

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre, 28029 Madrid, Spain.

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http://www.pnas.org/lookup/doi/10.1073/pnas.1611861114
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http://dx.doi.org/10.1073/pnas.1611861114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206536PMC
December 2016

The BLUEPRINT Data Analysis Portal.

Cell Syst 2016 11 15;3(5):491-495.e5. Epub 2016 Nov 15.

Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain; Spanish Bioinformatics Institute INB-ISCIII ES-ELIXIR, Madrid 28029, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919098PMC
November 2016

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

Cell 2016 11;167(5):1415-1429.e19

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300907PMC
November 2016

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 11;167(5):1398-1414.e24

Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Strangeways Research Laboratory, University of Cambridge, Wort's Causeway, Cambridge CB1 8RN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674163144
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http://dx.doi.org/10.1016/j.cell.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119954PMC
November 2016

Alternative Splicing May Not Be the Key to Proteome Complexity.

Trends Biochem Sci 2017 02 3;42(2):98-110. Epub 2016 Oct 3.

Structural Biology and Bioinformatics Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro, 3, 28029 Madrid, Spain; National Bioinformatics Institute (INB), Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro, 3, 28029 Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2016.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526280PMC
February 2017

An expanded evaluation of protein function prediction methods shows an improvement in accuracy.

Authors:
Yuxiang Jiang Tal Ronnen Oron Wyatt T Clark Asma R Bankapur Daniel D'Andrea Rosalba Lepore Christopher S Funk Indika Kahanda Karin M Verspoor Asa Ben-Hur Da Chen Emily Koo Duncan Penfold-Brown Dennis Shasha Noah Youngs Richard Bonneau Alexandra Lin Sayed M E Sahraeian Pier Luigi Martelli Giuseppe Profiti Rita Casadio Renzhi Cao Zhaolong Zhong Jianlin Cheng Adrian Altenhoff Nives Skunca Christophe Dessimoz Tunca Dogan Kai Hakala Suwisa Kaewphan Farrokh Mehryary Tapio Salakoski Filip Ginter Hai Fang Ben Smithers Matt Oates Julian Gough Petri Törönen Patrik Koskinen Liisa Holm Ching-Tai Chen Wen-Lian Hsu Kevin Bryson Domenico Cozzetto Federico Minneci David T Jones Samuel Chapman Dukka Bkc Ishita K Khan Daisuke Kihara Dan Ofer Nadav Rappoport Amos Stern Elena Cibrian-Uhalte Paul Denny Rebecca E Foulger Reija Hieta Duncan Legge Ruth C Lovering Michele Magrane Anna N Melidoni Prudence Mutowo-Meullenet Klemens Pichler Aleksandra Shypitsyna Biao Li Pooya Zakeri Sarah ElShal Léon-Charles Tranchevent Sayoni Das Natalie L Dawson David Lee Jonathan G Lees Ian Sillitoe Prajwal Bhat Tamás Nepusz Alfonso E Romero Rajkumar Sasidharan Haixuan Yang Alberto Paccanaro Jesse Gillis Adriana E Sedeño-Cortés Paul Pavlidis Shou Feng Juan M Cejuela Tatyana Goldberg Tobias Hamp Lothar Richter Asaf Salamov Toni Gabaldon Marina Marcet-Houben Fran Supek Qingtian Gong Wei Ning Yuanpeng Zhou Weidong Tian Marco Falda Paolo Fontana Enrico Lavezzo Stefano Toppo Carlo Ferrari Manuel Giollo Damiano Piovesan Silvio C E Tosatto Angela Del Pozo José M Fernández Paolo Maietta Alfonso Valencia Michael L Tress Alfredo Benso Stefano Di Carlo Gianfranco Politano Alessandro Savino Hafeez Ur Rehman Matteo Re Marco Mesiti Giorgio Valentini Joachim W Bargsten Aalt D J van Dijk Branislava Gemovic Sanja Glisic Vladmir Perovic Veljko Veljkovic Nevena Veljkovic Danillo C Almeida-E-Silva Ricardo Z N Vencio Malvika Sharan Jörg Vogel Lakesh Kansakar Shanshan Zhang Slobodan Vucetic Zheng Wang Michael J E Sternberg Mark N Wass Rachael P Huntley Maria J Martin Claire O'Donovan Peter N Robinson Yves Moreau Anna Tramontano Patricia C Babbitt Steven E Brenner Michal Linial Christine A Orengo Burkhard Rost Casey S Greene Sean D Mooney Iddo Friedberg Predrag Radivojac

Genome Biol 2016 09 7;17(1):184. Epub 2016 Sep 7.

Department of Computer Science and Informatics, Indiana University, Bloomington, IN, USA.

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http://dx.doi.org/10.1186/s13059-016-1037-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015320PMC
September 2016

The Markyt visualisation, prediction and benchmark platform for chemical and gene entity recognition at BioCreative/CHEMDNER challenge.

Database (Oxford) 2016 19;2016. Epub 2016 Aug 19.

ESEI - Department of Computer Science, University of Vigo, Ourense, Spain Small Molecule Discovery Platform, Molecular Therapeutics Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain

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http://dx.doi.org/10.1093/database/baw120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001550PMC
November 2017

Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity.

Genome Biol 2016 07 8;17(1):152. Epub 2016 Jul 8.

Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1186/s13059-016-1003-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939006PMC
July 2016

KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily.

BMC Genomics 2016 06 23;17 Suppl 2:396. Epub 2016 Jun 23.

Center for Biological Sequence Analysis (CBS), Systems Biology Department, Technical University of Denmark (DTU), Kemitorvet, Building 208, 2800 Kgs., Lyngby, Denmark.

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http://dx.doi.org/10.1186/s12864-016-2723-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928150PMC
June 2016

Chromatin Regulators as a Guide for Cancer Treatment Choice.

Mol Cancer Ther 2016 07 16;15(7):1768-77. Epub 2016 May 16.

Institut Curie, PSL Research University, CNRS, UMR3664, Equipe Labellisée Ligue contre le Cancer, Paris, France. Sorbonne Universités, UPMC Universite Paris 06, CNRS, UMR3664, Paris, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-1008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936925PMC
July 2016

ISCB's initial reaction to New England Journal of Medicine editorial on data sharing.

Bioinformatics 2017 09;33(18):2968

International Society for Computational Biology, Inc. (ISCB), 9650 Rockville Pike Bethesda, Maryland 20814, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870847PMC
September 2017

Somatic Embryonic FGFR2 Mutations in Keratinocytic Epidermal Nevi.

J Invest Dermatol 2016 08 19;136(8):1718-1721. Epub 2016 Apr 19.

Department of Dermatology, Parc de Salut Mar, Hospital del Mar, Barcelona, Spain; Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.03.040DOI Listing
August 2016

Epigenomic Co-localization and Co-evolution Reveal a Key Role for 5hmC as a Communication Hub in the Chromatin Network of ESCs.

Cell Rep 2016 Feb 28;14(5):1246-1257. Epub 2016 Jan 28.

Structural Biology and BioComputing Programme, Spanish National Cancer Research Center - CNIO, Melchor Fernandez Almagro 3, 28029 Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.01.008DOI Listing
February 2016

The potential clinical impact of the release of two drafts of the human proteome.

Expert Rev Proteomics 2015 23;12(6):579-93. Epub 2015 Oct 23.

d Structural Biology and Bioinformatics Programme , Spanish National Cancer Research Centre (CNIO) , Madrid , Spain.

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http://dx.doi.org/10.1586/14789450.2015.1103186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732427PMC
April 2017

From residue coevolution to protein conformational ensembles and functional dynamics.

Proc Natl Acad Sci U S A 2015 Nov 20;112(44):13567-72. Epub 2015 Oct 20.

Institute of Structural and Molecular Biology, University College London, London WC1H 0AJ, United Kingdom; Department of Chemistry, University College London, London WC1H 0AJ, United Kingdom

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http://www.pnas.org/lookup/doi/10.1073/pnas.1508584112
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http://dx.doi.org/10.1073/pnas.1508584112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640757PMC
November 2015

wKinMut-2: Identification and Interpretation of Pathogenic Variants in Human Protein Kinases.

Hum Mutat 2016 Jan 20;37(1):36-42. Epub 2015 Oct 20.

Center for Biological Sequence Analysis (CBS), Systems Biology Department, Technical University of Denmark (DTU), Kongens Lyngby 2800, Denmark.

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http://dx.doi.org/10.1002/humu.22914DOI Listing
January 2016

APPRIS WebServer and WebServices.

Nucleic Acids Res 2015 Jul 18;43(W1):W455-9. Epub 2015 May 18.

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain

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http://dx.doi.org/10.1093/nar/gkv512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489225PMC
July 2015

The evolutionary fate of alternatively spliced homologous exons after gene duplication.

Genome Biol Evol 2015 Apr 29;7(6):1392-403. Epub 2015 Apr 29.

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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https://academic.oup.com/gbe/article-lookup/doi/10.1093/gbe/
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http://dx.doi.org/10.1093/gbe/evv076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494069PMC
April 2015

CHEMDNER: The drugs and chemical names extraction challenge.

J Cheminform 2015 19;7(Suppl 1 Text mining for chemistry and the CHEMDNER track):S1. Epub 2015 Jan 19.

Structural Computational Biology Group, Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre, Calle Melchor Fernndez Almagro, 3, Madrid, Spain.

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http://dx.doi.org/10.1186/1758-2946-7-S1-S1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331685PMC
March 2015

Structure-PPi: a module for the annotation of cancer-related single-nucleotide variants at protein-protein interfaces.

Bioinformatics 2015 Jul 11;31(14):2397-9. Epub 2015 Mar 11.

Structural Biology and BioComputing Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btv142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495296PMC
July 2015

Alternative splicing and co-option of transposable elements: the case of TMPO/LAP2α and ZNF451 in mammals.

Bioinformatics 2015 Jul 2;31(14):2257-61. Epub 2015 Mar 2.

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre, Madrid 28029, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btv132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495291PMC
July 2015

Most highly expressed protein-coding genes have a single dominant isoform.

J Proteome Res 2015 Apr 11;14(4):1880-7. Epub 2015 Mar 11.

†Unidad de Proteómica and ‡Laboratorio de Proteómica Cardiovascular, Centro Nacional de Investigaciones Cardiovasculares, 28029 Madrid, Spain.

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http://pubs.acs.org/doi/10.1021/pr501286b
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http://dx.doi.org/10.1021/pr501286bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4768900PMC
April 2015

Detection of significant protein coevolution.

Bioinformatics 2015 Jul 24;31(13):2166-73. Epub 2015 Feb 24.

Computational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), C/ Darwin 3, 28049 Madrid and Structural Bioinformatics Group, Spanish National Cancer Research Centre (CNIO), C/ Melchor Fernández Almagro 3, 28029 Madrid, Spain.

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http://bioinformatics.oxfordjournals.org/content/31/13/2166.
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http://bioinformatics.oxfordjournals.org/content/early/2015/
Web Search
http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
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http://dx.doi.org/10.1093/bioinformatics/btv102DOI Listing
July 2015

FUN-L: gene prioritization for RNAi screens.

Bioinformatics 2015 Jun 8;31(12):2052-3. Epub 2015 Feb 8.

Research Department of Structural & Molecular Biology, University College London, London, UK, Cell Biology/Biophysics Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany, Inflamex-Laboratoire Analyse Géométrie et Applications, Université Paris Nord-Sorbonne, France, Structural Bioinformatics Group, Spanish National Cancer Research Centre (CNIO) and Spanish National Bioinformatics Institute (INB), Madrid, Spain, Institute of Molecular and Cell Biology, and Institute of Computer Science, University of Tartu, Tartu, Estonia and Department of Molecular Biology and Biochemistry-CIBER de Enfermedades Raras, University of Malaga, Malaga, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btv073DOI Listing
June 2015

Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia.

Genome Med 2015 28;7(1). Epub 2015 Jan 28.

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Center (CNIO), 28029 Madrid, Spain.

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http://genomemedicine.com/content/7/1/8
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http://dx.doi.org/10.1186/s13073-014-0125-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308895PMC
January 2015

ChiTaRS 2.1--an improved database of the chimeric transcripts and RNA-seq data with novel sense-antisense chimeric RNA transcripts.

Nucleic Acids Res 2015 Jan 20;43(Database issue):D68-75. Epub 2014 Nov 20.

Structural Biology and BioComputing Program, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain.

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http://academic.oup.com/nar/article/43/D1/D68/2439073/ChiTaR
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http://dx.doi.org/10.1093/nar/gku1199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383979PMC
January 2015

Colorectal cancer classification based on gene expression is not associated with FOLFIRI response.

Nat Med 2014 Nov;20(11):1230-1

Gastrointestinal Cancer Clinical Research Unit, Clinical Research Programme, Spanish National Cancer Research Center (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1038/nm.3701DOI Listing
November 2014

Summary of the BioLINK SIG 2013 meeting at ISMB/ECCB 2013.

Bioinformatics 2015 Jan 14;31(2):297-8. Epub 2014 Jul 14.

Department of Computing and Information Systems, The University of Melbourne, Parkville VIC 3010, Australia Department of Computer and Information Sciences, University of Delaware, Newark, DE 19716, USA, MITRE Corporation, Bedford, MA 01730, USA, Spanish Institute of Bioinformatics, Madrid, Spain and Spanish National Centre for Cancer Research, Madrid, Spain.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btu412DOI Listing
January 2015

Analyzing the first drafts of the human proteome.

J Proteome Res 2014 Aug 16;13(8):3854-5. Epub 2014 Jul 16.

‡Spanish National Cancer Research Centre (CNIO), Melchor Fernandez Almagro, 3, Madrid 28029, Spain.

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http://dx.doi.org/10.1021/pr500572zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334283PMC
August 2014

The pseudo GTPase CENP-M drives human kinetochore assembly.

Elife 2014 Jul 8;3:e02978. Epub 2014 Jul 8.

Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Dortmund, Germany Centre for Medical Biotechnology, Faculty of Biology, University of Duisburg-Essen, Essen, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080450PMC
http://dx.doi.org/10.7554/eLife.02978DOI Listing
July 2014