Alfonso Corrales

Alfonso Corrales

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Alfonso Corrales

Alfonso Corrales

Publications by authors named "Alfonso Corrales"

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Disease Activity Influences Cardiovascular Risk Reclassification Based on Carotid Ultrasound in Patients with Psoriatic Arthritis.

J Rheumatol 2019 Nov 15. Epub 2019 Nov 15.

From the Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain; Division of Rheumatology, Hospital Doctor Negrín, Las Palmas de Gran Canaria, Spain; University of Cantabria - IDIVAL, Santander, Spain and CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; School of Medicine, University of Cantabria, Santander, Spain; Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Division of Rheumatology, Hospital Universitario de Canarias, Tenerife, Spain. Address correspondence to Dr. Iván Ferraz-Amaro. Division of Rheumatology, Hospital Universitario de Canarias. 38320 Santa Cruz de Tenerife. Spain. Email: or Dr. Miguel Á. González-Gay. Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain. Email:

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http://dx.doi.org/10.3899/jrheum.190729DOI Listing
November 2019

Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice.

Semin Arthritis Rheum 2019 08 5;49(1):126-135. Epub 2019 Jan 5.

Departments of Rheumatology, Internal Medicine and Pathology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Universidad de Cantabria, Santander, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00490172183057
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http://dx.doi.org/10.1016/j.semarthrit.2019.01.003DOI Listing
August 2019

Predictors of positive F-FDG PET/CT-scan for large vessel vasculitis in patients with persistent polymyalgia rheumatica.

Semin Arthritis Rheum 2019 Feb 18;48(4):720-727. Epub 2018 May 18.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain; University of Cantabria, School of Medicine, Santander, Spain; Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2018.05.007DOI Listing
February 2019

Detection of high cardiovascular risk patients with ankylosing spondylitis based on the assessment of abdominal aortic calcium as compared to carotid ultrasound.

Arthritis Res Ther 2018 08 29;20(1):195. Epub 2018 Aug 29.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Avenida de Valdecilla, s/n, 39008, Santander, Spain.

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http://dx.doi.org/10.1186/s13075-018-1684-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116452PMC
August 2018

Implication of osteoprotegerin and sclerostin in axial spondyloarthritis cardiovascular disease: study of 163 Spanish patients.

Clin Exp Rheumatol 2018 Mar-Apr;36(2):302-309. Epub 2017 Dec 15.

Epidemiol., Genetics, Atherosclerosis Res. Group on Systemic Inflamm. Diseases, IDIVAL; School of Medicine, Univ. of Cantabria, Santander, Spain; Cardiovascular Pathophysiol. & Genomics Res. Unit, Faculty of Health Sciences, Univ. Witwatersrand, S.Africa.

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June 2018

Cardiovascular risk stratification in axial spondyloarthritis: carotid ultrasound is more sensitive than coronary artery calcification score to detect high-cardiovascular risk axial spondyloarthritis patients.

Clin Exp Rheumatol 2018 Jan-Feb;36(1):73-80. Epub 2017 Aug 28.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain.

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April 2018

Relative Risk Chart Score for the Assessment of the Cardiovascular Risk in Young Patients with Ankylosing Spondylitis.

Int J Rheumatol 2018 15;2018:1847894. Epub 2018 Feb 15.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain.

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http://dx.doi.org/10.1155/2018/1847894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832112PMC
February 2018

Carotid ultrasound in the cardiovascular risk stratification of patients with ankylosing spondylitis: results of a population-based study.

Clin Exp Rheumatol 2016 Sep-Oct;34(5):885-892. Epub 2016 Aug 31.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, University of Cantabria, Santander, Spain.

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January 2017

Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers.

Autoimmun Rev 2016 Nov 1;15(11):1013-1030. Epub 2016 Aug 1.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain; School of Medicine, University of Cantabria, Santander, Spain; Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972163017
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http://dx.doi.org/10.1016/j.autrev.2016.07.026DOI Listing
November 2016

Anti-tumor necrosis factor-alpha therapy improves endothelial function and arterial stiffness in patients with moderate to severe psoriasis: A 6-month prospective study.

J Dermatol 2016 Nov 7;43(11):1267-1272. Epub 2016 Apr 7.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marqués de Valdecilla, University of Cantabria, Santander, Spain.

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http://dx.doi.org/10.1111/1346-8138.13398DOI Listing
November 2016

Increased prevalence of subclinical atherosclerosis in patients with hidradenitis suppurativa (HS).

J Am Acad Dermatol 2016 Aug 8;75(2):329-35. Epub 2016 Jun 8.

Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, Instituto de Investigación Marqués de Valdecilla, University of Cantabria, Santander, Cantabria, Spain.

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http://dx.doi.org/10.1016/j.jaad.2016.03.025DOI Listing
August 2016

Asymmetric dimethylarginine but not osteoprotegerin correlates with disease severity in patients with moderate-to-severe psoriasis undergoing anti-tumor necrosis factor-α therapy.

J Dermatol 2016 Apr 14;43(4):389-94. Epub 2015 Sep 14.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain.

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http://dx.doi.org/10.1111/1346-8138.13094DOI Listing
April 2016

Subclinical atherosclerosis is not increased in patients with non-radiographic axial spondyloarthritis.

Clin Exp Rheumatol 2016 Jan-Feb;34(1):159-60. Epub 2016 Jan 8.

Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain.

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April 2016

Decreased expression of methylene tetrahydrofolate reductase (MTHFR) gene in patients with rheumatoid arthritis.

Clin Exp Rheumatol 2016 Jan-Feb;34(1):106-10. Epub 2016 Feb 2.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain.

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April 2016

The Framingham Score and the Systematic Coronary Risk Evaluation at Low Cutoff Values Are Useful Surrogate Markers of High-risk Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis.

J Rheumatol 2016 Mar 15;43(3):486-94. Epub 2016 Jan 15.

From the Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand; Department of Rheumatology, Charlotte Maxeke Johannesburg Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Instituto de Investigación Santaria Valdecilla (IDIVAL); Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander; Cardiology Division, Hospital Lucus Augusti, Lugo; Health Research Institute of Santiago de Compostela (IDIS), Division of Rheumatology, Clinical University Hospital of Santiago de Compostela, Santiago de Compostela, Spain.P.H. Dessein, MD, FCP (SA), FRCP (UK), PhD, Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand; A. Corrales, MD, Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL; R. Lopez-Mejias, PhD, Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL; A. Solomon, MBChB, FCP (SA), Department of Rheumatology, Charlotte Maxeke Johannesburg Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand; A.J. Woodiwiss, PhD, Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand; J. Llorca, MD, PhD, Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBERESP, IDIVAL; G.R. Norton, MBChB, PhD, Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand; F.

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http://dx.doi.org/10.3899/jrheum.150510DOI Listing
March 2016

Vitamin D receptor GATG haplotype association with atherosclerotic disease in patients with rheumatoid arthritis.

Atherosclerosis 2016 Feb 11;245:139-42. Epub 2015 Dec 11.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Department, IDIVAL, Santander, Spain; Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Health Research Institute of Santiago de Compostela (IDIS), Division of Rheumatology, Clinical University Hospital of Santiago de Compostela, Santiago de Compostela, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.12.011DOI Listing
February 2016

Lack of association between JAK3 gene polymorphisms and cardiovascular disease in Spanish patients with rheumatoid arthritis.

Biomed Res Int 2015 1;2015:318364. Epub 2015 Mar 1.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Disease, Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Avenida de Valdecilla s/n, 39008 Santander, Spain ; Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg 2000, South Africa.

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http://dx.doi.org/10.1155/2015/318364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359874PMC
December 2015

TNF-related apoptosis-inducing ligand and cardiovascular disease in rheumatoid arthritis.

Clin Exp Rheumatol 2015 Jul-Aug;33(4):491-7. Epub 2015 May 11.

Cardiovascular Pathophysiology and Genomics Research Unit, University of the Witwatersrand, Johannesburg, South Africa; and Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology, IDIVAL, Santander, Spain.

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October 2015

Atherosclerotic disease in axial spondyloarthritis: increased frequency of carotid plaques.

Clin Exp Rheumatol 2015 May-Jun;33(3):315-20. Epub 2015 May 25.

Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, and Cardiovascular Pathophysiology and Genomics Research Unit, University of the Witwatersrand, Johannesburg, South Africa.

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August 2015

Carotid artery plaque in women with rheumatoid arthritis and low estimated cardiovascular disease risk: a cross-sectional study.

Arthritis Res Ther 2015 Mar 11;17:55. Epub 2015 Mar 11.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Avenida Cardenal Herrera Oria s/n, Santander, 39011, Spain.

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http://arthritis-research.com/content/17/1/55
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http://dx.doi.org/10.1186/s13075-015-0576-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376096PMC
March 2015

Osteoprotegerin concentrations relate independently to established cardiovascular disease in rheumatoid arthritis.

J Rheumatol 2015 Jan 1;42(1):39-45. Epub 2014 Nov 1.

From the Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Department of Internal Medicine, Hospital Universitario Marques de Valdecilla, and the Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and Fundación Instituto de Investigación Marqués de Valdecilla, and Red Temática de Investigación Cooperativa en Envejecimiento y Fragilidad (RETICEF), and CIBER Epidemiología y Salud Pública (CIBERESP), Santander; the Rheumatology Division, Hospital Universitario de Canarias, Tenerife; the Cardiology Division, Hospital Lucus Augusti, Lugo, Spain; the Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.P.H. Dessein and M.A. Gonzalez-Gay share senior authorship.R. López-Mejias, PhD; B. Ubilla, BSc; F. Genre, PhD; A. Corrales, MD, PhD; R. Blanco, MD, PhD, Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marques de Valdecilla, IFIMAV; J.L. Hernández, MD, PhD, Department of Internal Medicine, Hospital Universitario Marques de Valdecilla, University of Cantabria, RETICEF, IFIMAV; I. Ferraz-Amaro, MD, Rheumatology Division, Hospital Universitario de Canarias; L. Tsang; P.H. Dessein, MD, FCP(SA), FRCP(UK), PhD, Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand; J. Llorca, MD, PhD, Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBERESP, IFIMAV; C. Gonzalez-Juanatey, MD, PhD, Cardiology Division, Hospital Lucus Augusti; M.A. Gonzalez-Gay, MD, PhD, Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marques de Valdecilla, IFIMAV

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http://www.jrheum.org/content/42/1/39.full.pdf
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http://www.jrheum.org/cgi/doi/10.3899/jrheum.140690
Publisher Site
http://dx.doi.org/10.3899/jrheum.140690DOI Listing
January 2015

Investigation of a PON1 gene polymorphism (rs662 polymorphism) as predictor of subclinical atherosclerosis in patients with rheumatoid arthritis.

Ann Rheum Dis 2014 Sep 15;73(9):1749-50. Epub 2014 May 15.

Department of Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain.

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http://dx.doi.org/10.1136/annrheumdis-2014-205543DOI Listing
September 2014

Carotid ultrasound is useful for the cardiovascular risk stratification of patients with rheumatoid arthritis: results of a population-based study.

Ann Rheum Dis 2014 Apr 16;73(4):722-7. Epub 2013 Mar 16.

Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, , Santander, Spain.

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http://dx.doi.org/10.1136/annrheumdis-2012-203101DOI Listing
April 2014

Angiopoietin-2 serum levels correlate with severity, early onset and cardiovascular disease in patients with rheumatoid arthritis.

Clin Exp Rheumatol 2013 Sep-Oct;31(5):761-6. Epub 2013 Jul 24.

Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IFIMAV, Santander, Spain.

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December 2013

Lack of association between Toll-like receptor 4 gene polymorphisms and giant cell arteritis.

Rheumatology (Oxford) 2011 Sep 17;50(9):1562-8. Epub 2011 May 17.

Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, Facultad de Medicina, Universidad de Cantabria, Santander, Spain.

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http://dx.doi.org/10.1093/rheumatology/ker168DOI Listing
September 2011

Interleukin-1RN gene polymorphisms in elderly patients with rheumatic inflammatory chronic conditions: Association of IL-1RN*2/2 genotype with polymyalgia rheumatica.

Hum Immunol 2009 Jan 19;70(1):49-54. Epub 2008 Nov 19.

Hospital Universitario Marqués de Valdecilla, Universidad de Cantabria, Santander, Fundación Marqués de Valdecilla-Instituto de Formación e Investigación Margués de Valdecilla, Spain.

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http://dx.doi.org/10.1016/j.humimm.2008.10.011DOI Listing
January 2009

Outcome of late-onset rheumatoid arthritis.

Clin Rheumatol 2005 Sep 5;24(5):485-9. Epub 2005 Mar 5.

Division of Rheumatology, Hospital Sierrallana, Universidad de Cantabria, Santander, Spain.

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http://dx.doi.org/10.1007/s10067-004-1067-4DOI Listing
September 2005

HLA-DRB1 allele distribution in polymyalgia rheumatica and giant cell arteritis: influence on clinical subgroups and prognosis.

Semin Arthritis Rheum 2004 Aug;34(1):454-64

Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, Facultad de Medicine, Universidad de Cantabria, Cantabria, Spain.

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http://dx.doi.org/10.1016/j.semarthrit.2003.12.001DOI Listing
August 2004